Suhas Ganesh
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Assistant Professor (Adjunct) of Psychiatry
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Research at a Glance
Yale Co-Authors
Frequent collaborators of Suhas Ganesh's published research.
Publications Timeline
A big-picture view of Suhas Ganesh's research output by year.
Deepak Cyril Dsouza, MBBS, MD
Angus Nairn, PhD
Rolando Garcia Milian, MLS, AHIP
TuKiet Lam, PhD, BS
19Publications
125Citations
Publications
2024
Behavioral, Cognitive and Electrophysiological Presentation and Short-Term Course of Cannabis Related First Episode Psychosis
D'Souza D, Raj J, Ganesh S, Goyal N, Vidya K, Tikka S, Shreekantiah U, Murthy P, Sinha V, Ram D, Cortes J. Behavioral, Cognitive and Electrophysiological Presentation and Short-Term Course of Cannabis Related First Episode Psychosis. Biological Psychiatry 2024, 95: s29. DOI: 10.1016/j.biopsych.2024.02.076.Peer-Reviewed Original ResearchAltered neuroepithelial morphogenesis and migration defects in iPSC-derived cerebral organoids and 2D neural stem cells in familial bipolar disorder
Phalnikar K, Srividya M, Mythri S, Vasavi N, Ganguly A, Kumar A, S P, Kalia K, Mishra S, Dhanya S, Paul P, Holla B, Ganesh S, Reddy P, Sud R, Viswanath B, Muralidharan B. Altered neuroepithelial morphogenesis and migration defects in iPSC-derived cerebral organoids and 2D neural stem cells in familial bipolar disorder. Oxford Open Neuroscience 2024, 3: kvae007. PMID: 38638145, PMCID: PMC11024480, DOI: 10.1093/oons/kvae007.Peer-Reviewed Original ResearchAltmetricConceptsPatient organoidsNeural stem cellsBipolar disorderStem cellsTranscriptome analysis of controlPatient-derived organoidsFamilial bipolar disorderMigration defectsNeural stem cell culturesDysregulation of genesFamilial BDBD patientsCausative genetic variantsSox2-positiveNeurodevelopmental aberrationsNeurodevelopmental anomaliesIPSC-derived cerebral organoidsProgenitor proliferationStem cell culturesAbnormal positionPatientsNeuronal migrationCortical organoidsMolecular deficitsCycling progenitorsHybrid Tele-cognitive Behavioural Therapy (Ht-CBT) for Obsessive-compulsive Disorder: An Innovation Integrating In-person and Online Psychotherapy
Ganesh S, Sharma L, Das B. Hybrid Tele-cognitive Behavioural Therapy (Ht-CBT) for Obsessive-compulsive Disorder: An Innovation Integrating In-person and Online Psychotherapy. Indian Journal Of Psychological Medicine 2024, 46: 276-278. PMID: 38699761, PMCID: PMC11062316, DOI: 10.1177/02537176231219768.Peer-Reviewed Original ResearchAltmetricPsychopharmacological Treatment of Schizophrenia
Singh N, Ganesh S, D'Souza D. Psychopharmacological Treatment of Schizophrenia. 2024 DOI: 10.1016/b978-0-323-95702-1.00177-9.Peer-Reviewed Original ResearchConceptsAntipsychotic drugsPositive symptoms of schizophreniaPharmacological treatment of schizophreniaTreatment-resistant schizophreniaPharmacological treatmentSymptoms of schizophreniaTreatment of schizophreniaAcute psychotic episodeNeuroleptic malignant syndromeNegative symptomsPositive symptomsExtrapyramidal symptomsPsychotic episodeCognitive deficitsCognitive symptomsMalignant syndromeSchizophreniaPrevent relapseSide effectsMaintenance treatmentLong-actingDopamineAssociated with significant side effectsMedication adherenceProportion of patients
2023
The Acute Effects of Cannabinoids in Patients with Psychotic Illness
Ganesh S, Henquet C, Sewell R, Kuepper R, Ranganathan M, D’Souza D. The Acute Effects of Cannabinoids in Patients with Psychotic Illness. 2023, 225-239. DOI: 10.1017/9781108943246.023.Peer-Reviewed Original ResearchAltmetricConceptsMental illnessMental health teamsHealth policy implicationsHigh-potency cannabisStages of neurodevelopmentPotential adverse effectsAcute effectsHealth teamsPsychotic illnessImpact of exposureCannabis dependenceAdverse effectsIllnessCannabisCannabinoidsSynthetic cannabinoidsPsychosisNew research findingsAssociationComplex associationPatientsNeurodevelopmentPutative modelSchizophreniaPeripheral signature of altered synaptic integrity in young onset cannabis use disorder: A proteomic study of circulating extracellular vesicles
Ganesh S, Lam T, Garcia-Milian R, D'Souza D, Nairn A, Elgert K, Eitan E, Ranganathan M. Peripheral signature of altered synaptic integrity in young onset cannabis use disorder: A proteomic study of circulating extracellular vesicles. The World Journal Of Biological Psychiatry 2023, 24: 603-613. PMID: 36994633, PMCID: PMC10471733, DOI: 10.1080/15622975.2023.2197039.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsNeuron-derived extracellular vesiclesLabel-free quantification mass spectrometryProteomic studiesCannabis use disorderExtracellular vesiclesMass spectrometry proteomic analysisDifferential proteomic profilesAdapter proteinProteomic analysisPost-synaptic densityPeripheral signatureMolecular basisProteomic profilesProteinMarkers of neuropathologyBrain tissue samplesSynaptic pathologyVesiclesSynaptic integrityImmunoaffinity methodUse disordersFunctional integrityImportant insightsNeuropathologyPilot study
2022
Whole exome sequencing in dense families suggests genetic pleiotropy amongst Mendelian and complex neuropsychiatric syndromes
Ganesh S, Vemula A, Bhattacharjee S, Mathew K, Ithal D, Navin K, Nadella R, Viswanath B, Sullivan P, Jain S, Purushottam M. Whole exome sequencing in dense families suggests genetic pleiotropy amongst Mendelian and complex neuropsychiatric syndromes. Scientific Reports 2022, 12: 21128. PMID: 36476812, PMCID: PMC9729597, DOI: 10.1038/s41598-022-25664-7.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSequence kernel association testKernel association testWhole-exome sequencing studiesExome sequencing studiesUnique genesGenetic architectureCase-control association analysisDeleterious variantsSequencing studiesWhole-exome sequencingMendelian syndromesAssociation analysisCriteria of rarityPleiotropic influenceGenesWES studyFunctional consequencesSignificant overrepresentationGenetic pleiotropyExome sequencingAffected individualsFamilyImportant insightsUnrelated controlsAssociation Test
2020
Association of SLC1A1 Gene Polymorphism With Obsessive Compulsive Disorder in a Sample From Southern India
Shukla T, Nadella R, J. R, Ganesh S, Nestadt G, Purushottam M, Jain S, Reddy Y, Viswanath B. Association of SLC1A1 Gene Polymorphism With Obsessive Compulsive Disorder in a Sample From Southern India. Experimental And Clinical Psychopharmacology 2020, 28: 617-621. PMID: 31985241, DOI: 10.1037/pha0000348.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsObsessive-compulsive disorderTreatment responseAge of onsetSRI treatment responseSignificant associationClinical parametersMini International Neuropsychiatric InterviewGenotype/allele frequenciesSymptom dimensionsSpecialty OCD clinicAdequate trialFull respondersNeuropsychiatric InterviewHealthy controlsBrain volumeGene polymorphismsOCD clinicDisease severityCase-control association analysisSymptom severityOCD patientsOCD casesGenotype frequenciesCompulsive disorderAssociationAdverse childhood experiences in families with multiple members diagnosed to have psychiatric illnesses
Someshwar A, Holla B, Pansari Agarwal P, Thomas A, Jose A, Joseph B, Raju B, Karle H, Muthukumaran M, Kodancha P, Kumar P, Reddy P, Kumar Nadella R, Naik S, Mitra S, Mallappagiri S, Sreeraj V, Balachander S, Ganesh S, Murthy P, Benegal V, Reddy J, Jain S, Mahadevan J, Viswanath B, Rao N, Narayanaswamy J, Sivakumar P, Kandasamy A, Kesavan M, Mehta U, Venkatasubramanian G, John J, Mukherjee O, Purushottam M, Kannan R, Mehta B, Kandavel T, Binukumar B, Saini J, Jayarajan D, Shyamsundar A, Moirangthem S, Vijay Kumar K, Thirthalli J, Chandra P, Gangadhar B, Panicker M, Bhalla U, Chattarji S, Varghese M, Raghu P, Rao M. Adverse childhood experiences in families with multiple members diagnosed to have psychiatric illnesses. Australian & New Zealand Journal Of Psychiatry 2020, 54: 1086-1094. PMID: 32538179, DOI: 10.1177/0004867420931157.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsFirst-degree relativesAdverse childhood experience exposureMajor psychiatric conditionsAdverse childhood experiencesObsessive-compulsive disorderSeverity scorePsychiatric conditionsSubstance dependencePsychiatric illnessBipolar disorderAdverse Childhood Experiences International QuestionnaireRisk first-degree relativesChildhood experiencesCo-occurring diagnosesAge of onsetEarly ageInteraction of diagnosisOngoing longitudinal studyPsychiatric diagnosis
2019
O11.2. CHARACTERIZING CANNABINOID INDUCED ACUTE PERSISTENT PSYCHOSIS (CIAPP) AS A POSSIBLE SUBTYPE OF SCHIZOPHRENIA USING DEEP LEARNING
Ganesh S, Vidya K, Tikka S, Raj J, Gahalout R, Skosnik P, Luddy C, Goyal N, Ram D, D’Souza D, Cortes-Briones J. O11.2. CHARACTERIZING CANNABINOID INDUCED ACUTE PERSISTENT PSYCHOSIS (CIAPP) AS A POSSIBLE SUBTYPE OF SCHIZOPHRENIA USING DEEP LEARNING. Schizophrenia Bulletin 2019, 45: s194-s194. PMCID: PMC6455269, DOI: 10.1093/schbul/sbz021.258.Peer-Reviewed Original Research
Links & Media
News
- January 02, 2022Source: The American Journal of Psychiatry
Cannabis and Psychosis: Recent Epidemiological Findings Continuing the “Causality Debate”
- August 10, 2021
Ganesh Receives ECIP Travel Award for 2021 Virtual World Congress of Psychiatric Genetics
- December 09, 2020Source: Molecular Psychiatry
Preliminary in vivo evidence of lower hippocampal synaptic density in cannabis use disorder
- September 04, 2018
Eight Yale affiliates awarded NARSAD Young Investigator Grants