Skip to Main Content
Yale School of Medicine
YSM Home

INFORMATION FOR

Silvio Inzucchi, MD

DownloadHi-Res Photo

Research

About

Titles

Professor of Medicine (Endocrinology)

Biography

Dr. Inzucchi received his undergraduate degree from Fordham University in New York City and his M.D. degree from Harvard Medical School in Boston, Massachusetts. He completed his residency in Internal Medicine and his post-doctoral Fellowship in Endocrinology and Metabolism at Yale-New Haven Hospital, in New Haven, Connecticut, USA. He is currently Professor of Medicine at the Yale University School of Medicine in New Haven, where he serves as Clinical Chief of the Section of Endocrinology, Medical Director of the Yale Diabetes Center, and Program Director of the Endocrinology & Metabolism Fellowship.

Dr. Inzucchi has been an invited lecturer both nationally and internationally on many topics, most pertaining to clinical diabetes management. He has authored or co-authored more than 500 manuscripts, chapters, monographs, and abstracts, some published in the most prestigious medical journals, including the New England Journal of Medicineand JAMA. A former member of the editorial board of Diabetes Careand Associate Editor of the Journal of Clinical Endocrinology and Metabolism, Dr. Inzucchi served as co-chair of the writing group for the 2012 and 2015 ADA-EASD Position Statements on the Management of Hyperglycemia in Type 2 Diabetes.

His current research interests include pharmacological antihyperglycemic therapy in both the inpatient and outpatient settings; and the link between type 2 diabetes, insulin resistance, and cardiovascular complications. He has held leadership roles in several large clinical trials related to diabetes medications and their cardiovascular impact.

Dr. Inzucchi also has a large academic clinical practice involving a wide spectrum of patients with endocrine diseases, with a focus on diabetes and pituitary and adrenal diseases.

Last Updated on April 07, 2025.

Appointments

Other Departments & Organizations

Education & Training

MD
Harvard University (1985)
BS
Fordham University (1981)

Research

Overview

Medical Research Interests

Atherosclerosis; Diabetes Mellitus; Endocrinology; Hyperglycemia; Insulin Resistance; Metabolism

Research at a Glance

Yale Co-Authors

Frequent collaborators of Silvio Inzucchi's published research.

Publications

2026

2025

  • Impact of Oral Semaglutide on Kidney Outcomes in People With Type 2 Diabetes: Results From the SOUL Randomized Trial
    Mann J, Marx N, Deanfield J, Emerson S, Inzucchi S, McGuire D, Mulvagh S, Pop-Busui R, Poulter N, Engelmann M, Hovingh G, Belmar N, Idorn T, Jeppesen O, Birkenfeld A, Amod A, Mankovsky B, Desouza C, Gorgojo-Martinez J, Arechavaleta R, Tu S, Buse J, McGuire D, Buse J, Mann J, Marx N, Deanfield J, Emerson S, Inzucchi S, Mulvagh S, Pop-Busui R, Poulter N, Engelmann M, Hovingh G, Schelde P, Birkenfeld A, Amod A, Mankovsky B, Desouza C, Gorgojo-Martinez J, Arechavaleta R, Tu S, Francisco J, García R, Chow F, Watada H, Yoon K, Singh P, Matthew, Manghi F, Pozzi J, Lorenzatti A, Visco V, Piskorz D, Nardone L, Chahin M, Labarta M, Luquez C, MacKinnon I, Pieber T, Prager R, Fließer-Görzer E, Ebenbichler C, Fasching P, Mathieu C, De Block C, Duyck F, Heyns E, Lapauw B, Turatti L, Franco D, Rea R, Lisboa R, Salles J, Saraiva J, Fonseca A, Vidotti M, Leite S, Aggarwal N, Bajaj H, Schlosser R, Noronha L, Pedersen S, Peterson S, Tellier G, Weisnagel J, Beca S, Alasaad H, Punthakee Z, Mancini J, Tytus R, Ransom T, Connelly K, Husain M, Tsoukas M, Ji L, Liu J, Yuan G, Ye X, Dong X, Bian F, Angelo A, Garcia R, Erazo I, Ruiz E, Mesa J, Canecki-Varzic S, Loncar J, Simegi-Djekic V, Kurir T, Tusek S, Rahelic D, Marusic S, Kruljac I, Vitkovic D, Oznerova M, Vrkoc J, Doležalová B, Haluzik M, Jankovec Z, Olsovsky J, Zemanova J, Kyselova P, Smahelova A, Gregersen S, Olsen A, Mikkelsen D, Egstrup K, Pedersen-Bjergaard U, Potier L, Borot S, Gaborit B, Monier A, Pradignac A, Verges B, Larroumet A, Thuan J, Kellerer M, Lüdemann J, Esser M, Kahrmann G, Kempe H, Koch T, Axthelm C, Paschen B, Rose L, Schaum T, Schulze J, Staudenmeyer A, Wenzl-Bauer V, W. R, Thomas N, Mohan V, Reddy V, Rao P, Sahay R, Singh J, Prakash A, Tandon N, Marwah T, Chaudhury T, Ghosh S, Kanungo A, Mittal N, Jacob J, Chadha M, Chawla M, Bhagwat N, Jain S, Thulaseedharan N, Girithara G, Desai A, Sharma S, Murthy S, Sethi B, Kadam Y, Kesavadev J, Daxini B, Chawla R, Gopalakrishnan U, Baruah M, Reddy S, Suryanarayana K, Singh K, Saboo B, Aharon-Hananel G, Hochberg I, Sofer Y, Tirosh A, Shimon I, Vishlitzky V, Bashkin A, Tsur A, Shechter M, Andreozzi F, Setola E, Consoli A, Lupoli R, Genovese S, Maranghi M, Lauro D, Citarrella R, Fadini G, Murdolo G, Di Carlo A, Giorgino F, Buscemi S, Hanaoka K, Osonoi T, Ohashi H, Ezaki H, Yuki H, Kiyosue A, Hata Y, Sugawara M, Domae H, Iwata H, Nishida Y, Igarashi M, Fujino S, Oiwa A, Oh F, Sueyoshi A, Murakami T, Tanaka M, Idogaki A, Onaka H, Mizote I, Doi M, Ebisui O, Tanabe M, Natsuaki M, Jinnouchi H, Nakamura S, Mohamed W, Yahaya N, Ratnasingam J, Ong T, Mohamad M, Merican N, Ghani R, Adam N, Fam T, Tan F, Villegas E, Gonzalez-Galvez G, Peralta D, Pech C, Ulloa A, Molina H, Elizondo R, Ruiz J, Cantú E, van Bemmel T, de Valk H, Kooy A, Lieverse L, Landewe-Cleuren S, Hoogenberg K, van Raalte D, Jebbink M, Oldenburg-Ligtenberg C, Abbink-Zandbergen E, Mihai B, Crisan C, Filip I, Busegeanu M, Roman G, Mot A, Nicoara A, Anghel V, Pletea N, Suciu M, Strajer D, Cernea S, Zilov A, Kobalava Z, Ruyatkina L, Suplotova L, Sergeeva-Kondrachenko M, Yanovskaya M, Kargina L, Ignatyeva A, Astamirova K, Zalevskaya A, Zagrebelnaya O, Frolova E, Peskov A, Mishchenko O, Otroshchenko O, Gaysina L, Shabelnikova O, Saprina T, Lysenko T, Kunitsyna M, Zyangirova S, Lalic N, Lalic K, Zivkovic T, Kikovic S, Djukic A, Pesic M, Dimic D, Stokic E, Mitrovic M, Polovina S, Djordjevic M, Sosovec D, Pella D, Donicova V, Prasekova S, Koleny D, Culak J, Cerna K, Hundza V, Gmitrov J, Lacka J, Plasil R, Bacus H, Bhorat Q, Joshi P, Lakha D, Makan V, Ntusi N, Padayachee T, Seeber M, Pillay D, Joshi M, Mayet L, Lee J, Kim S, Min K, Kang E, Lee W, Choi S, Lee C, Suárez A, Ordóñez M, Quintana A, Ramos P, Cigarrán S, Barrios C, González A, Jodar E, Lista J, Portillo C, Carrasco C, Tinahones F, Cigarrán S, Huang C, Chen S, Buranasupkajorn P, Sriwijitkamol A, Buranapin S, Suwanagool A, Tantiwong P, Boonyavarakul A, Benjachareonwong S, Leelawattana R, Vathesatogkit P, Deerochanawong C, Sonmez Y, Oguz A, Tabak O, Kocak M, Sariakcali B, Bayram F, Guclu M, Gurkan E, Kebapci N, Comlekci A, Acibucu F, Ahbab S, Bilen H, Urbanovych A, Kuskalo P, Bondarets I, Petrosyan O, Pashkovska N, Oleksyk O, Kaydashev I, Maliar K, Myshanych G, Bain S, Black D, Johnston P, Dang C, Dhatariya K, English P, Field B, Grimmer P, Gunstone A, Ray S, Tatovic D, Kernohan A, Lindsay R, Mcknight J, Park A, Patel D, Philip S, Randeva H, Sathyapalan T, Turner W, Wyatt N, Allison D, Awasty V, Ayele E, Bajaj C, Budoff M, Busch R, Casaubon L, Chaidarun S, Chochinov R, Chu J, Daboul N, Dang A, Everhart B, Arambasick J, Fink R, Fitz-Patrick D, Fogarty C, Gilbert M, Johnson D, Krishnasamy S, Lane W, Nakhle S, Levenson D, O’Donnell P, Weiss D, Risser J, Wierum C, Sivalingam K, Gupta D, Philis-Tsimikas A, Pratley R, Mirza L, Snyder B, Rasouli N, Porter J, Ledesma G, Powell T, Tandron I, Lingvay I, Reed J, Patel M, Lovre D, Chaicha-Brom T, Jantzi C, Brautigam D, Bao S, Mbogua C, Zemel L, Hasan S, Rosenstock J, Tran H, Poremba J, Baker C, Prier K, Chilka S, Agaiby J, Condit J, Eagerton D, Huffman D, Cornett G, Traylor H, Brinson C, Bays H, Jerkins T, Nicol P, Siddiqui I, Hewitt M, Odugbesan A, Lillestol M, Thrasher J, Gandy W, Pant N, Nagelberg S, Cannon K, Anderson M, Bhargava A, Doshi A, Jardula M, Montero M, Purighalla R, Warren M, Harris K, Jackson R, Khaira A, Gonzalez-Orozco B, Gagianas P, Pantalone K, Murray A. Impact of Oral Semaglutide on Kidney Outcomes in People With Type 2 Diabetes: Results From the SOUL Randomized Trial. Diabetes Care 2025, 49: 257-265. PMID: 41380027, PMCID: PMC12824789, DOI: 10.2337/dc25-1080.
    Peer-Reviewed Original Research
  • Iodine for the Outpatient Management of Graves’ Disease: A Case Series of 7 Patients
    Magvanjav O, MacLeod R, Balasubramanian P, Mekala K, Peter P, Inzucchi S, Majumdar S. Iodine for the Outpatient Management of Graves’ Disease: A Case Series of 7 Patients. AACE Clinical Case Reports 2025, 13: 83-87. PMID: 41641309, PMCID: PMC12866150, DOI: 10.1016/j.aed.2025.10.015.
    Peer-Reviewed Case Reports and Technical Notes
  • Differences in Prevalence and Incidence of Electrocardiogram Abnormalities and Cardiovascular Autonomic Neuropathy Among Randomized Glucose-lowering Treatments in Early Type 2 Diabetes: The Glycemia Reduction Approaches in Diabetes (GRADE) Cohort
    Pop-Busui R, Rosin S, Butera N, Krause-Steinrauf H, Abou Assi H, Garg R, Inzucchi S, Katona A, McGill J, Mudaliar S, Schade D, Seaquist E, Tiktin M, Soliman E, Green J, Crandall J, McKee M, Behringer-Massera S, Brown-Friday J, Xhori E, Ballentine-Cargill K, Duran S, Estrella H, Gonzalez de la torre S, Lukin J, Phillips L, Burgess E, Olson D, Rhee M, Wilson P, Raines T, Boers J, Costello J, Maher-Albertelli M, Mungara R, Savoye L, White C, Gullett C, Holloway L, Morehead F, Person S, Sibymon M, Tanukonda S, Adams C, Ross A, Balasubramanyam A, Gaba R, Gonzalez Hattery E, Ideozu A, Jimenez J, Montes G, Wright C, Hollander P, Roe E, Jackson A, Smiley A, Burt P, Estrada L, Chionh K, Ismail-Beigi F, Falck-Ytter C, Sayyed Kassem L, Sood A, Tiktin M, Kulow T, Newman C, Stancil K, Cramer B, Iacoboni J, Kononets M, Sanders C, Tucker L, Werner A, Maxwell A, McPhee G, Patel C, Colosimo L, Krol A, Goland R, Pring J, Alfano L, Kringas P, Hausheer C, Tejada J, Gumpel K, Kirpitch A, Schneier H, Green J, AbouAssi H, Chatterjee R, Feinglos M, English Jones J, Khan S, Kimpel J, Zimmer R, Furst M, Satterwhite B, Thacker C, Evans Kreider K, Mariash C, Mather K, Ismail H, Lteif A, Mullen M, Hamilton T, Patel N, Riera G, Jackson M, Pirics V, Aguillar D, Howard D, Hurt S, Bergenstal R, Carlson A, Martens T, Johnson M, Hill R, Hyatt J, Jensen C, Madden M, Martin D, Willis H, Konerza W, Yang S, Kleeberger K, Passi R, Fortmann S, Herson M, Mularski K, Glauber H, Prihoda J, Ash B, Carlson C, Ramey P, Schield E, Torgrimson-Ojerio B, Arnold K, Kauffman B, Panos E, Sahnow S, Bays K, Berame K, Cook J, Ghioni D, Gluth J, Schell K, Criscola J, Friason C, Jones S, Nazarov S, Barzilay J, Rassouli N, Puttnam R, Ojoawo B, Nelson R, Curtis M, Hollis B, Sanders-Jones C, Stokes K, El-Haqq Z, Kolli A, Tran T, Wexler D, Larkin M, Meigs J, Chambers B, Dushkin A, Rocchio G, Yepes M, Steiner B, Dulin H, Cayford M, Chu K, DeManbey A, Hillard M, Martin K, Thangthaeng N, Gurry L, Kochis R, Raymond E, Ripley V, Stevens C, Park J, Aroda V, Ghazi A, Magee M, Ressing A, Loveland A, Hamm M, Hurtado M, Kuhn A, Leger J, Manandhar L, Mwicigi F, Sanchez O, Young T, Garg R, Lagari-Libhaber V, Florez H, Valencia W, Marks J, Casula S, Oropesa-Gonzalez L, Hue L, Cuadot A, Nieto-Martinez R, Riccio Veliz A, Gutt M, Kendal Y, Veciana B, Ahmann A, Aby-Daniel D, Joarder F, Morimoto V, Sprague C, Yamashita D, Cady N, Rivera-Eschright N, Kirchhoff P, Morales Gomez B, Adducci J, Goncharova A, Hox S, Petrovitch H, Matwichyna M, Jenkins V, Broadwater L, Ishii R, Bermudez N, Hsia D, Cefalu W, Greenway F, Waguespack C, King E, Fry G, Dragg A, Gildersleeve B, Arceneaux J, Haynes N, Thomassie A, Pavlionis M, Bourgeois B, Hazlett C, Mudaliar S, Henry R, Boeder S, Pettus J, Diaz E, Garcia-Acosta D, Maggs S, DeLue C, Stallings A, Castro E, Hernandez S, Krakoff J, Curtis J, Killean T, Khalid M, Joshevama E, Diaz E, Martin D, Tsingine K, Karshner T, Albu J, Pi-Sunyer F, Frances S, Maggio C, Ellis E, Bastawrose J, Gong X, Banerji M, August P, Lee M, Lorber D, Brown N, Josephson D, Thomas L, Tsovian M, Cherian A, Jacobson M, Mishko M, Kirkman M, Buse J, Diner J, Dostou J, Machineni S, Young L, Bergamo K, Goley A, Kerr J, Largay J, Guarda S, Cuffee J, Culmer D, Fraser R, Almeida H, Coffer S, Debnam E, Kiker L, Morton S, Josey K, Fuller G, Garvey W, Cherrington A, Dyer D, Lawson M, Griffith O, Agne A, McCullars S, Cohen R, Craig J, Rogge M, Burton K, Kersey K, Wilson C, Lipp S, Vonder Meulen M, Adkins C, Onadeko T, Rasouli N, Baker C, Schroeder E, Razzaghi M, Lyon C, Penaloza R, Underkofler C, Lorch R, Douglass S, Steiner S, Sivitz W, Cline E, Knosp L, McConnell J, Lowe T, Herman W, Pop-Busui R, Tan M, Martin C, Waltje A, Katona A, Goodhall L, Eggleston R, Kuo S, Bojescu S, Bule S, Kessler N, LaSalle E, Whitley K, Seaquist E, Bantle A, Harindhanavudhi T, Kumar A, Redmon B, Bantle J, Coe M, Mech M, Taddese A, Lesne L, Smith S, Desouza C, Kuechenmeister L, Shivaswamy V, Burbach S, Rodriguez M, Seipel K, Alfred A, Morales A, Eggert J, Lord G, Taylor W, Tillson R, Schade D, Adolphe A, Burge M, Duran-Valdez E, Martinez J, Bancroft A, Kunkel S, Ali Jamaleddin Ahmad F, Hernandez McGinnis D, Pucchetti B, Scripsick E, Zamorano A, DeFronzo R, Cersosimo E, Abdul-Ghani M, Triplitt C, Juarez D, Garza R, Verastiqui H, Wright K, Puckett C, Raskin P, Rhee C, Abraham S, Jordan L, Sao S, Morton L, Smith O, Osornio Walker L, Schnurr-Breen L, Ayala R, Kreymer R, Sturgess D, Utzschneider K, Kahn S, Alarcon-Casas Wright L, Boyko E, Tsai E, Trence D, Trikudanathan S, Fattaleh B, Montgomery B, Atkinson K, Kozedub A, Concepcion T, Moak C, Prikhodko N, Rhothisen S, Elasy T, Martin S, Shackelford L, Goidel R, Hinkle N, Lovell C, Myers J, Lipps Hogan J, McGill J, Salam M, Schweiger T, Kissel S, Recklein C, Clifton M, Tamborlane W, Camp A, Gulanski B, Inzucchi S, Pham K, Alguard M, Gatcomb P, Lessard K, Perez M, Iannone L, Magenheimer E, Montosa A, Cefalu W, Fradkin J, Burch H, Bremer A, Nathan D, Lachin J, Kahn S, Krause-Steinrauf H, Larkin M, Tiktin M, Wexler D, Burch H, Younes N, Bebu I, Butera N, Buys C, Fagan A, Gao Y, Ghosh A, Gramzinski M, Hall S, Kazemi E, Legowski E, Liu H, Suratt C, Tripputi M, Arey A, Backman M, Bethepu J, Lund C, Mangat Dhaliwal P, McGee P, Mesimer E, Ngo L, Steffes M, Seegmiller J, Saenger A, Arends V, Gabrielson D, Conner T, Warren S, Day J, Huminik J, Scrymgeour A, Soliman E, Pokharel Y, Zhang Z, Campbell C, Hu J, Keasler L, Hensley S, Li Y, Herman W, Kuo S, Martin C, Waltje A, Mihalcea R, Min D, Perez-Rosas V, Prosser L, Resnicow K, Ye W, Shao H, Zhang P, Luchsinger J, Sanchez D, Assuras S, Groessl E, Sakha F, Chong H, Hillery N. Differences in Prevalence and Incidence of Electrocardiogram Abnormalities and Cardiovascular Autonomic Neuropathy Among Randomized Glucose-lowering Treatments in Early Type 2 Diabetes: The Glycemia Reduction Approaches in Diabetes (GRADE) Cohort. Diabetes Care 2025, 48: 1960-1970. PMID: 40986645, PMCID: PMC12583396, DOI: 10.2337/dc25-1087.
    Peer-Reviewed Original Research
See All Publications

Clinical Care

Overview

Silvio E. Inzucchi, MD, director of the Yale Medicine Diabetes Center, treats patients who suffer from diabetes as well as pituitary and adrenal disorders. “Endocrinology is fascinating, and we are usually able to help patients improve their quality of life through multidisciplinary care and academic approaches to endocrine conditions,” he says.

Dr. Inzucchi is a professor or medicine (endocrinology) at Yale School of Medicine and the clinical director of the section of endocrinology. In his research, Dr. Inzucchi, studies the cardiovascular effects of diabetes medications and glucose management in the hospital. Named a “top doctor” locally and nationally, Dr. Inzucchi has also received Yale’s David J. Leffell Prize for Clinical Excellence. The prize is given to individuals who demonstrate the highest level of clinical expertise, commitment to teaching and compassion for patients.

He says he has developed an effective personal approach to treating patients, carefully honed over 30 years at Yale. It includes being on top of the latest advances, but also responding to each patient’s individual needs. “I like to try to draw people out in terms of who they are, what’s important to them, their life experiences and their family. Such an approach resonates with patients because they don’t want to be seen as a patient, they want to be treated as a person,” he says.

Clinical Specialties

Endocrinology; Diabetes Medicine & Management

Fact Sheets

See All Fact Sheets On Yale Medicine

Board Certifications

  • Internal Medicine

    Certification Organization
    AB of Internal Medicine
    Original Certification Date
    1988

Yale Medicine News

See All News On Yale Medicine

Are You a Patient?

View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.

View Doctor Profile

Get In Touch

Contacts

Email
Appointment Number
Clinic Fax Number

Locations

  • Patient Care Locations

    Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.

    See Patient Care Locations

Events

Jul 202615Wednesday
Aug 20265Wednesday
Aug 202619Wednesday
Sep 20262Wednesday
See All Events