Shubham Bansal
Postdoctoral AssociateAbout
Titles
Postdoctoral Associate
Biography
Shubham Bansal is a Postdoctoral Associate in the Department of Radiology & Biomedical Imaging at the Yale School of Medicine. His doctoral research focuses on advancing drug discovery and targeted drug delivery systems, with specific expertise in reactive oxygen species (ROS), gaseous signaling molecules, and click chemistry. Dr. Bansal earned both his PhD and MS in Chemistry from Georgia State University. Throughout his academic career, his work has been recognized with numerous distinctions, including the David W. Boykin Graduate Fellowship in Medicinal Chemistry and the Center for Diagnostics and Therapeutics “Fellow of the Year” award. He is a co-inventor of a pending patent for redox-sensitive prodrugs, and his research is widely published in high-impact scientific journals, including the Journal of Medicinal Chemistry, Chemical Science, and Analytical Chemistry.
Last Updated on July 25, 2026.
Appointments
Radiology & Biomedical Imaging
Postdoctoral AssociatePrimary
Other Departments & Organizations
Education & Training
- PhD
- Georgia State University, Department of Chemistry (2026)
- MS
- Georgia State University, Department of Chemistry (2022)
Research
Publications
2026
Targeting Highly Reactive Oxygen Species (hROS) for Prodrug Activation through a Cascade Reaction with Kinetic Tunability (CReKT) to Effect Linker Cleavage
Kondengadan S, Bansal S, Lu W, Choudhury M, Wang B. Targeting Highly Reactive Oxygen Species (hROS) for Prodrug Activation through a Cascade Reaction with Kinetic Tunability (CReKT) to Effect Linker Cleavage. Journal Of Medicinal Chemistry 2026, 69: 9196-9214. PMID: 41837562, PMCID: PMC13126685, DOI: 10.1021/acs.jmedchem.5c03627.Peer-Reviewed Original ResearchReactive oxygen species (ROS) research in drug discovery and drug delivery: Can the medium Be a Trojan Horse disguised as something benign?
Bansal S, Wang B. Reactive oxygen species (ROS) research in drug discovery and drug delivery: Can the medium Be a Trojan Horse disguised as something benign? Journal Of Enzyme Inhibition And Medicinal Chemistry 2026, 41: 2631215. PMID: 41711685, PMCID: PMC12922419, DOI: 10.1080/14756366.2026.2631215.Peer-Reviewed Original ResearchClick Chemistry in Delivering Gaseous Signaling Molecules
Liu D, Bansal S, Gori M, Wang B. Click Chemistry in Delivering Gaseous Signaling Molecules. Topics In Heterocyclic Chemistry 2026, 1-26. DOI: 10.1007/7081_2025_104.Peer-Reviewed Original Research
2025
Entry Inhibitors of SARS-CoV-2 Targeting the Transmembrane Domain of the Spike Protein
Lyles K, Stone S, Singh P, Patterson L, Natekar J, Pathak H, Varshnaya R, Elsharkawy A, Liu D, Bansal S, Faniyi O, Tang S, Yang X, Mulpuri N, Hamelberg D, Kang C, Wang B, Kumar M, Luo M. Entry Inhibitors of SARS-CoV-2 Targeting the Transmembrane Domain of the Spike Protein. Viruses 2025, 17: 989. PMID: 40733606, PMCID: PMC12300635, DOI: 10.3390/v17070989.Peer-Reviewed Original ResearchDetection and Analysis of Reactive Oxygen Species (ROS): Buffer Components Are Not Bystanders
Bansal S, Gori M, Quaye J, Gadda G, Wang B. Detection and Analysis of Reactive Oxygen Species (ROS): Buffer Components Are Not Bystanders. Analytical Chemistry 2025, 97: 14931-14942. PMID: 40459125, PMCID: PMC12291042, DOI: 10.1021/acs.analchem.4c07070.Peer-Reviewed Original ResearchThioether Oxidation Chemistry in Reactive Oxygen Species (ROS)-Sensitive Trigger Design: A Kinetic Analysis
Abdelfattah A, Bansal S, Quaye J, Kondengadan S, Gadda G, Wang B. Thioether Oxidation Chemistry in Reactive Oxygen Species (ROS)-Sensitive Trigger Design: A Kinetic Analysis. Organic Letters 2025, 27: 3071-3076. PMID: 40106701, PMCID: PMC11959603, DOI: 10.1021/acs.orglett.5c00747.Peer-Reviewed Original Research
2024
A critical factor in reactive oxygen species (ROS) studies: the need to understand the chemistry of the solvent used: the case of DMSO
Bansal S, Wang B. A critical factor in reactive oxygen species (ROS) studies: the need to understand the chemistry of the solvent used: the case of DMSO. Chemical Science 2024, 15: 17843-17851. PMID: 39397818, PMCID: PMC11469295, DOI: 10.1039/d4sc05038j.Peer-Reviewed Original ResearchCarbon Monoxide as a Potential Therapeutic Agent: A Molecular Analysis of Its Safety Profiles
Bansal S, Liu D, Mao Q, Bauer N, Wang B. Carbon Monoxide as a Potential Therapeutic Agent: A Molecular Analysis of Its Safety Profiles. Journal Of Medicinal Chemistry 2024, 67: 9789-9815. PMID: 38864348, PMCID: PMC11215727, DOI: 10.1021/acs.jmedchem.4c00823.Peer-Reviewed Original ResearchFolate-conjugated organic CO prodrugs: Synthesis and CO release kinetic studies
Kondengadan S, Bansal S, Yang X, Wang B. Folate-conjugated organic CO prodrugs: Synthesis and CO release kinetic studies. Medicinal Chemistry Research 2024, 33: 1410-1422. DOI: 10.1007/s00044-024-03232-0.Peer-Reviewed Original Research
2022
Click chemistry and drug delivery: A bird's-eye view
Kondengadan S, Bansal S, Yang C, Liu D, Fultz Z, Wang B. Click chemistry and drug delivery: A bird's-eye view. Acta Pharmaceutica Sinica B 2022, 13: 1990-2016. PMID: 37250163, PMCID: PMC10213991, DOI: 10.1016/j.apsb.2022.10.015.Peer-Reviewed Original Research