Shubham Bansal
Postdoctoral AssociateAbout
Titles
Postdoctoral Associate
Biography
Shubham Bansal is a Postdoctoral Associate in the Department of Radiology & Biomedical Imaging at the Yale School of Medicine. His doctoral research focuses on advancing drug discovery and targeted drug delivery systems, with specific expertise in reactive oxygen species (ROS), gaseous signaling molecules, and click chemistry. Dr. Bansal earned both his PhD and MS in Chemistry from Georgia State University. Throughout his academic career, his work has been recognized with numerous distinctions, including the David W. Boykin Graduate Fellowship in Medicinal Chemistry and the Center for Diagnostics and Therapeutics “Fellow of the Year” award. He is a co-inventor of a pending patent for redox-sensitive prodrugs, and his research is widely published in high-impact scientific journals, including the Journal of Medicinal Chemistry, Chemical Science, and Analytical Chemistry.
Appointments
Radiology & Biomedical Imaging
Postdoctoral AssociatePrimary
Other Departments & Organizations
Education & Training
- PhD
- Georgia State University, Department of Chemistry (2026)
- MS
- Georgia State University, Department of Chemistry (2022)
Research
Overview
- Conceived and developed a bidirectional fluorescent probe for simultaneous detection of oxidative and reductive stress in living cells, providing a new way to monitor dynamic changes in cellular redox environments. Beyond this dual redox-sensing capability, this work introduces a new chemistry of selective sulfone reduction in hypoxia, opening new opportunities for the development of hypoxia-responsive fluorescent probes.
- Identified and demonstrated that commonly used solvents (DMSO), buffers, and cell culture media can skew experimental results and their interpretations. Additionally, provided a framework that improves future work.
- Developed new ROS-responsive prodrug system and co-inventor on two patent applications involving redox-responsive probes and prodrug technologies.