Sarah McCollum
BiostatisticianCards
About
Research
Publications
2025
Prevalence and phenotype of food allergy in children with cystic fibrosis
Nguyen H, Shabanova V, McCollum S, Polk B, Lee T, Whittington K, Cunha P, Bruscia E, Egan M, Emmenegger M, Leeds S. Prevalence and phenotype of food allergy in children with cystic fibrosis. Annals Of Allergy Asthma & Immunology 2025, 135: 419-424. PMID: 40550267, DOI: 10.1016/j.anai.2025.06.024.Peer-Reviewed Original ResearchCystic fibrosisCF patientsFood allergyUS pediatric populationElectronic medical recordsPediatric populationPhenotypes of food allergyRetrospective pediatric cohort studyPrevalence of FAFA prevalenceCystic Fibrosis Foundation RegistryMale CF patientsUnited StatesPediatric CF patientsPancreatic enzyme replacementPediatric cohort studyIgE-mediated FACohort studyEstimated prevalenceInclusion criteriaMedical informationDevelopment of FAMedical recordsFA diagnosisPrevalence1186-P: A Short-Term Low Carbohydrate Diet Improves Glycemia in Adolescents and Young Adults with Type 1 Diabetes—Results from a Randomized Crossover Study
NALLY L, LUKASIK J, HERZOG R, MITTENDORFER B, GOSS A, SAVOYE M, ROSE P, MCCOLLUM S, SHABANOVA V, SHERR J. 1186-P: A Short-Term Low Carbohydrate Diet Improves Glycemia in Adolescents and Young Adults with Type 1 Diabetes—Results from a Randomized Crossover Study. Diabetes 2025, 74 DOI: 10.2337/db25-1186-p.Peer-Reviewed Original ResearchLow-carbohydrate dietRandomized Crossover StudyCrossover studyCarbohydrate dietPotential treatment optionStandard carbohydrate dietLower glycemic variabilityRandomized Controlled TrialsDietary recallsMetabolic kitchenTreatment optionsIncreasing hypoglycemiaImprove glycemiaGlycemic variabilityControlled TrialsT1DGlycemic benefitsWeekend daysHypoglycemiaIncreasing timeYoung adultsDietYouthGlycemiaHyperglycemiaPrevalence of Food Allergy in Children with Cystic Fibrosis
Nguyen H, Whittington K, McCollum S, Shabanova V, Polk B, Lee T, Bruscia E, Egan M, Leeds S. Prevalence of Food Allergy in Children with Cystic Fibrosis. The Journal Of Allergy And Clinical Immunology 2025, 155: ab41. DOI: 10.1016/j.jaci.2024.12.132.Peer-Reviewed Original ResearchAlterations in newborn metabolite patterns with preterm birth and diabetes in pregnancy
Buck C, McCollum S, Wang W, Lam T, Taylor S, Shabanova V. Alterations in newborn metabolite patterns with preterm birth and diabetes in pregnancy. Pediatric Research 2025, 98: 1023-1032. PMID: 39824937, PMCID: PMC12267566, DOI: 10.1038/s41390-025-03844-1.Peer-Reviewed Original ResearchPreterm infantsCardiometabolic outcomesMetabolite patternsStudy of termMetabolic changesInfluence of prematuritySkin fold thickness measurementsCohort of infantsUnique metabolic signatureNon-DM groupAdipose developmentExposure to diabetesArm circumference measurementsBody composition assessmentAssociated with adiposityBody fat percentAdverse growthDM exposurePreterm birthTargeted metabolomicsInfant bloodTerm groupDM groupGA groupPreterm
2024
Association Between High-Sensitivity Troponin (hs-cTnT) and Diagnosis of Myocarditis in Previously Healthy Pediatric Patients
Degen M, Leviter J, Bradley A, Karnik R, Ferdman D, McCollum S, Faherty E. Association Between High-Sensitivity Troponin (hs-cTnT) and Diagnosis of Myocarditis in Previously Healthy Pediatric Patients. Pediatric Cardiology 2024, 46: 2207-2213. PMID: 39126513, DOI: 10.1007/s00246-024-03621-7.Peer-Reviewed Original ResearchDiagnosis of myocarditisPediatric patientsHs-cTnTTroponin levelsCardiac diagnosisHigh-sensitivity troponin THealthy pediatric patientsHigh-sensitivity troponinHs-cTnT groupMedian peak levelSensitivity troponin levelsElevated hs-cTnTCut-off valueInitial troponin levelMyocarditis diagnosisAcute myocarditisTroponin valuesCardiac troponinPediatric populationTroponin TMyocarditisPatientsPeak levelsDiagnosisMyocardial tissue
2023
Longitudinal Assessment of Left Ventricular Function in Patients with Myopericarditis After mRNA COVID-19 Vaccination
NV B, McCollum S, Faherty E, Steele J, Karnik R. Longitudinal Assessment of Left Ventricular Function in Patients with Myopericarditis After mRNA COVID-19 Vaccination. Pediatric Cardiology 2023, 45: 1524-1532. PMID: 37294336, PMCID: PMC10251331, DOI: 10.1007/s00246-023-03200-2.Peer-Reviewed Original ResearchLeft ventricular longitudinal strainMRNA COVID-19 vaccinationCOVID-19 vaccinationSubclinical myocardial injuryEjection fractionFractional shorteningInitial presentationMyocardial injurySingle-center reviewMedian ejection fractionLeft ventricular functionVentricular longitudinal strainTime 0Area-length methodWilcoxon signed-rank testAcute illnessDiastolic functionVentricular functionDiastolic parametersLV functionRisk stratificationMyocardial recoveryTissue DopplerSigned-rank testMyopericarditisImpact of school‐supervised ultra‐long‐acting basal insulin injections on ketosis in youth with T1D and elevated haemoglobin A1c: A pilot study
Nally L, Sherr J, Tichy E, Weyman K, Urban A, Shabanova V, McCollum S, Steffen A, Tamborlane W, Van Name M. Impact of school‐supervised ultra‐long‐acting basal insulin injections on ketosis in youth with T1D and elevated haemoglobin A1c: A pilot study. Diabetic Medicine 2023, 40: e15123. PMID: 37078999, PMCID: PMC10524154, DOI: 10.1111/dme.15123.Peer-Reviewed Original ResearchConceptsBasal insulin injectionsDiabetic ketoacidosisPercent of participantsBlood β-hydroxybutyrateInsulin injectionsBasal insulin dosesBasal insulin typeType 1 diabetesManagement of youthDegludec groupSignificant ketosisAcute complicationsBasal insulinInsulin dosesRisk of ketosisInjected insulinHigher hemoglobinInsulin administrationElevated hemoglobinInsulin typeKetone levelsHigh riskSchool nursesDegludecLarger sample sizeParent Priorities in End-of-Life Care for Children With Cancer
Ananth P, Lindsay M, Mun S, McCollum S, Shabanova V, de Oliveira S, Pitafi S, Kirch R, Ma X, Gross C, Boyden J, Feudtner C, Wolfe J. Parent Priorities in End-of-Life Care for Children With Cancer. JAMA Network Open 2023, 6: e2313503. PMID: 37184834, PMCID: PMC10878399, DOI: 10.1001/jamanetworkopen.2023.13503.Peer-Reviewed Original ResearchValidated anxiety assessments among pediatric patients with peanut allergy on oral immunotherapy
Kaman K, Dhodapkar M, Shabanova V, McCollum S, Factor J, Leeds S. Validated anxiety assessments among pediatric patients with peanut allergy on oral immunotherapy. Annals Of Allergy Asthma & Immunology 2023, 130: 657-663. PMID: 36738780, DOI: 10.1016/j.anai.2023.01.028.Peer-Reviewed Original ResearchConceptsPeanut oral immunotherapyOral immunotherapyNon-white racePeanut allergyAnxiety scoresOlder cohortProspective cross-sectional cohort studyCross-sectional cohort studyHigher mean anxiety scoresMean anxiety scoreDiagnosable anxietyCohort studyMale patientsPediatric patientsFemale patientsFood allergySimilar patientsHigh prevalenceHigher scoresLife measuresLow prevalencePatientsSeparation anxiety scoresElectronic survey questionnaireAllergy
2022
Mechanistic Insights Into the Heterogeneity of Glucose Response Classes in Youths With Obesity: A Latent Class Trajectory Approach
Tricò D, McCollum S, Samuels S, Santoro N, Galderisi A, Groop L, Caprio S, Shabanova V. Mechanistic Insights Into the Heterogeneity of Glucose Response Classes in Youths With Obesity: A Latent Class Trajectory Approach. Diabetes Care 2022, 45: 1841-1851. PMID: 35766976, PMCID: PMC9346992, DOI: 10.2337/dc22-0110.Peer-Reviewed Original ResearchConceptsOral glucose tolerance testΒ-cell functionΒ-cell glucose sensitivityInsulin sensitivityGenetic risk profileMultiple oral glucose tolerance testsDifferent genetic risk profilesRisk profileMin oral glucose tolerance testLatent class trajectory analysisGlucose tolerance testImpaired insulin sensitivityPlasma glucose responseGlucose sensitivityClass 3Model-predicted probabilityClass 1Tolerance testProgressive impairmentMultiethnic cohortGlucose responseLongitudinal changesObesityTransient reductionInsulin kinetics