R. Ross MacLean, PhD
he/him/his
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Appointments
Psychiatry
Primary
Titles
Clinical Psychologist, VA CT Healthcare System
Contact Info
Psychiatry
VA Connecticut Healthcare System, 950 Campbell Ave (116B)
West Haven, CT 06516
United States
Appointments
Psychiatry
Primary
Titles
Clinical Psychologist, VA CT Healthcare System
Contact Info
Psychiatry
VA Connecticut Healthcare System, 950 Campbell Ave (116B)
West Haven, CT 06516
United States
Appointments
Psychiatry
Primary
Titles
Clinical Psychologist, VA CT Healthcare System
Contact Info
Psychiatry
VA Connecticut Healthcare System, 950 Campbell Ave (116B)
West Haven, CT 06516
United States
About
Titles
Associate Professor of Psychiatry
Clinical Psychologist, VA CT Healthcare SystemBiography
I graduated from Penn State with a PhD in Psychology in 2015. I completed both my predoctoral internship at VA Connecticut Healthcare System in West Haven after which I transitioned to a post-doctoral fellowship in the Mental Illness Research, Education, and Clinical Care (MIRECC). I joined the faculty at Yale School of Medicine in 2017 as an Assistant Professor. The gestalt of my clinical and research interests center around understanding the behavioral mechanisms underlying addictive behavior and developing treatments for addiction and co-occurring conditions that can be integrated into existing care. To that end, much of my current research uses mobile-based technology and experience sampling methodology to gain a better understanding of individual behavior an potentially highlight more effective ways of measuring treatment success.
Appointments
Psychiatry
Associate Professor on TermPrimary
Other Departments & Organizations
Education & Training
- Postdoctoral Fellowship (MIRECC)
- VA Connecticut Healthcare System (2017)
- PhD
- Pennsylvania State University, Psychology (2015)
- Predoctoral internship
- VA Connecticut Healthcare System (2015)
- MS
- Pennsylvania State University, Psychology (2011)
- BS
- University of Connecticut, Psychology (2004)
Research
Overview
Medical Subject Headings (MeSH)
Alcohol Drinking; Buprenorphine; Drug-Seeking Behavior; Mental Health; Methadone; Opioid-Related Disorders; Pain; Substance-Related Disorders; Tobacco Use
Research at a Glance
Yale Co-Authors
Frequent collaborators of R. Ross MacLean's published research.
Publications Timeline
A big-picture view of R. Ross MacLean's research output by year.
Research Interests
Research topics R. Ross MacLean is interested in exploring.
Mehmet Sofuoglu, MD, PhD
Elise DeVito, PhD
Tore Eid, MD, PhD
Mary Driscoll, PhD
Suzanne Spinola
Eugenia Buta, PhD
37Publications
304Citations
Opioid-Related Disorders
Alcohol Drinking
Buprenorphine
Methadone
Publications
2024
Efficacy of Integrating the Management of Pain and Addiction via Collaborative Treatment (IMPACT) in Individuals With Chronic Pain and Opioid Use Disorder: Protocol for a Randomized Clinical Trial of a Digital Cognitive Behavioral Treatment
MacLean R, Ankawi B, Driscoll M, Gordon M, Frankforter T, Nich C, Szollosy S, Loya J, Brito L, Ribeiro M, Edmond S, Becker W, Martino S, Sofuoglu M, Heapy A. Efficacy of Integrating the Management of Pain and Addiction via Collaborative Treatment (IMPACT) in Individuals With Chronic Pain and Opioid Use Disorder: Protocol for a Randomized Clinical Trial of a Digital Cognitive Behavioral Treatment. JMIR Research Protocols 2024, 13: e54342. PMID: 38506917, PMCID: PMC10993119, DOI: 10.2196/54342.Peer-Reviewed Original ResearchAltmetricThe relationship of pain intensity and opioid craving with delayed methadone dose: A preliminary study of individuals with opioid use disorder
MacLean R, Spinola S, Pittman B, Meyerovich J, Szollosy S, Wolkowicz N, Minnix S, Sofuoglu M. The relationship of pain intensity and opioid craving with delayed methadone dose: A preliminary study of individuals with opioid use disorder. British Journal Of Clinical Pharmacology 2024 PMID: 38439592, DOI: 10.1111/bcp.16027.Peer-Reviewed Original ResearchConceptsCold pressor testMethadone doseExperience of painOpioid cravingMethadone conditionTime course of painRelationship of pain intensityDose conditionsCourse of painAssessment of painOpioid use disorderCross-over designPain intensityPain thresholdIncreased riskPainStudy visitsPressor testDelayed dosesUse disorderCravingOpioidMethadone treatmentDoseMethadone
2023
Are opioids effective analgesics and is physiological opioid dependence benign? Revising current assumptions to effectively manage long‐term opioid therapy and its deprescribing
Manhapra A, MacLean R, Rosenheck R, Becker W. Are opioids effective analgesics and is physiological opioid dependence benign? Revising current assumptions to effectively manage long‐term opioid therapy and its deprescribing. British Journal Of Clinical Pharmacology 2023 PMID: 37990580, DOI: 10.1111/bcp.15972.Peer-Reviewed Original ResearchCitationsAltmetricConceptsLong-term opioid therapyOpioid therapyFunctional gainsChronic pain syndromeMaximum functional recoveryOngoing opioid crisisParadoxical worseningAnalgesic benefitAnalgesic therapyPain reliefPain syndromeEffective analgesicMost patientsAntinociceptive effectAntinociceptive systemChronic painFunctional recoveryOpioid actionOpioid dependenceMedical instabilityFunctional improvementPlacebo effectClinical principlesOpioid crisisTherapeutic inductionChronic pain and problematic substance use for veterans during COVID-19: the moderating role of psychological flexibility
Reilly E, Wolkowicz N, Heapy A, MacLean R, Duarte B, Chamberlin E, Harris J, Shirk S, Kelly M. Chronic pain and problematic substance use for veterans during COVID-19: the moderating role of psychological flexibility. Frontiers In Psychology 2023, 14: 1173641. PMID: 37205082, PMCID: PMC10185850, DOI: 10.3389/fpsyg.2023.1173641.Peer-Reviewed Original ResearchConceptsQuality of lifeProblematic substance useChronic painMental health functioningSubstance useHealth functioningCOVID-19Mental healthChronic pain diagnosesBetter mental health functioningPsychological flexibilityU.S. veteran populationPain severityComorbid conditionsPain diagnosisClinical managementPainBetter outcomesVeteran populationCertain veteransPhysical healthGreater psychological flexibilityShort ScreenerEmotional healthVeteransIntegrating cognitive bias modification for pain and opioid cues into medication for opioid use disorder clinical care: Feasibility, acceptability, and preliminary results
MacLean R, Heapy A, Waters A, Wolkowicz N, Szollosy S, Meyerovich J, Sofuoglu M. Integrating cognitive bias modification for pain and opioid cues into medication for opioid use disorder clinical care: Feasibility, acceptability, and preliminary results. Drug And Alcohol Dependence 2023, 246: 109857. PMID: 37004461, PMCID: PMC10189744, DOI: 10.1016/j.drugalcdep.2023.109857.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsTrial-level bias scoresOpioid cuesAB taskCognitive bias modification taskAttentional bias taskCognitive bias modificationComputer-based tasksPreliminary efficacyOpioid use disorderCurrent studyBias modificationBias taskBias scoresModification tasksCBM groupCBM tasksChronic painAcceptability measuresControl conditionTaskUse disordersClinical careCuesTime interactionParticipantsOpioid Use Disorder With Chronic Pain Increases Disease Burden and Service Use
MacLean RR, Sofuoglu M, Stefanovics E, Rosenheck R. Opioid Use Disorder With Chronic Pain Increases Disease Burden and Service Use. Psychological Services 2023, 20: 157-165. PMID: 34968125, PMCID: PMC9358616, DOI: 10.1037/ser0000607.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsOpioid use disorderChronic painMental health diagnosesService useUse disordersHealth AdministrationConcurrent opioid use disorderHealth diagnosisOngoing opioid epidemicOutpatient service useVeterans Health AdministrationMental health disordersSubstance use diagnosesSingle disorder groupsClinical service useOpioid prescriptionsAdditional comorbiditiesMultinomial regression analysisDisease burdenMedication fillsOpioid epidemicPrescription opiatesMedical conditionsMedical disordersUse diagnosesThreshold for the Pleasurable Effects of Nicotine Are Lower Than Its Reinforcing Effects During Self-Administration
MacLean RR, Eid T, Parida S, Gueorguieva R, DeVito EE, Sofuoglu M. Threshold for the Pleasurable Effects of Nicotine Are Lower Than Its Reinforcing Effects During Self-Administration. Experimental And Clinical Psychopharmacology 2023, 31: 37-45. PMID: 35254839, PMCID: PMC9448824, DOI: 10.1037/pha0000556.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsNicotine metabolite ratioDose of nicotineNicotine reinforcementSubjective effectsDiscriminative stimulus effectsHeart rate increaseDoses of nicotineSelf-administration procedureSubjective positive effectsDaily smokersBaseline cravingIntravenous nicotineOvernight abstinenceCigarette cravingDrug effectsMetabolite ratiosStimulus effectsSecondary analysisPlaceboSelf-AdministrationNicotine choiceTobacco productsNicotinePleasurable effectsYoung adults
2022
Pre‐implementation formative evaluation of cooperative pain education and self‐management expanding treatment for real‐world access: A pragmatic pain trial
Mattocks K, LaChappelle K, Krein S, DeBar L, Martino S, Edmond S, Ankawi B, MacLean R, Higgins D, Murphy J, Cooper E, Heapy A. Pre‐implementation formative evaluation of cooperative pain education and self‐management expanding treatment for real‐world access: A pragmatic pain trial. Pain Practice 2022, 23: 338-348. PMID: 36527287, DOI: 10.1111/papr.13195.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsCBT-CPChronic painPragmatic trialOngoing pragmatic trialVeterans Affairs sitesPrimary care cliniciansPragmatic clinical trialsVA Medical CenterEvidence-based treatmentsSystem-level factorsReal-world accessCognitive behavioral therapyPain intensityPain trialsCare cliniciansReferral pathwaysPain educationClinicians' lackClinical trialsMedical CenterSystem barriersQualitative interviewsReal-world settingIndividual qualitative interviewsClinicians' difficultyUsing Daily Ratings to Examine Treatment Dose and Response in Cognitive Behavioral Therapy for Chronic Pain: A Secondary Analysis of the Co-Operative Pain Education and Self-Management Clinical Trial
MacLean R, Buta E, Higgins D, Driscoll M, Edmond S, LaChappelle K, Ankawi B, Krein S, Piette J, Heapy A. Using Daily Ratings to Examine Treatment Dose and Response in Cognitive Behavioral Therapy for Chronic Pain: A Secondary Analysis of the Co-Operative Pain Education and Self-Management Clinical Trial. Pain Medicine 2022, 24: 846-854. PMID: 36484691, PMCID: PMC10250557, DOI: 10.1093/pm/pnac192.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPain intensityCognitive behavioral therapyCBT-CPChronic painTreatment responseDaily stepsSecondary analysisBehavioral therapyMeaningful changeChronic back painStrong evidence baseBack painPain educationTreatment weekClinical trialsNoninferiority trialTreatment benefitOutcome measuresWeek 4Treatment doseWeek 2Baseline weekMost respondersSurvival analysisStep countCocaine Use Disorder (CUD): Current Clinical Perspectives
Schwartz EKC, Wolkowicz NR, De Aquino JP, MacLean RR, Sofuoglu M. Cocaine Use Disorder (CUD): Current Clinical Perspectives. Substance Abuse And Rehabilitation 2022, 13: 25-46. PMID: 36093428, PMCID: PMC9451050, DOI: 10.2147/sar.s337338.Peer-Reviewed Original ResearchCitationsAltmetricConceptsCocaine use disorderCo-occurring disordersUse disordersCommon co-occurring disordersCurrent clinical perspectivesSubstance use disordersCognitive behavioral therapyMedication treatmentPharmacological treatmentRisk factorsCurrent treatmentDevastating disorderLarger sample sizeTreatment planChronic effectsCocaine useBehavioral treatmentClinical perspectiveBehavioral interventionsDisordersTreatmentFuture studiesMost individualsIndividualsSample size
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Psychiatry
VA Connecticut Healthcare System, 950 Campbell Ave (116B)
West Haven, CT 06516
United States