Rima Fawaz, MD
Associate Professor of Pediatrics (Gastroenterology & Hepatology)Cards
About
Research
Publications
2026
Liver stiffness in patients with Shwachman‐Diamond syndrome
Sabharwal S, Grover A, Mitchell P, Serino‐Cipoletta J, Shimamura A, Fawaz R. Liver stiffness in patients with Shwachman‐Diamond syndrome. JPGN Reports 2026, 7: 200-206. PMID: 42110137, PMCID: PMC13150996, DOI: 10.1002/jpr3.70138.Peer-Reviewed Original Research
2025
Diagnostic approaches for infants with cholestatic liver diseases: Position paper and perspectives of the Federation of International Societies of Pediatric Gastroenterology, Hepatology, and Nutrition
Chen H, Taylor S, Lee W, Ciocca M, El‐Guindi M, Yachha S, Fawaz R, Botero V, Treepongkaruna S, Gonzales E, Hadžić N. Diagnostic approaches for infants with cholestatic liver diseases: Position paper and perspectives of the Federation of International Societies of Pediatric Gastroenterology, Hepatology, and Nutrition. Journal Of Pediatric Gastroenterology And Nutrition 2025, 81: 1360-1377. PMID: 40977420, DOI: 10.1002/jpn3.70207.Peer-Reviewed Original ResearchPhenotypic Divergence of JAG1‐ and NOTCH2‐Associated Alagille Syndrome & Disease‐Specific NOTCH2 Variant Classification Guidelines
Vandriel S, Li L, She H, Wang J, Loomes K, Piccoli D, Jankowska I, Czubkowski P, Gliwicz‐Miedzińska D, D'Antiga L, Nicastro E, Lacaille F, Debray D, Sokal É, Demaret T, Fawaz R, Nastasio S, Kim K, Oh S, Fischler B, Arnell H, Larson‐Nath C, Hardikar W, Shankar S, Sundaram S, Chaidez A, Bulut P, Calvo P, Kasahara M, Blondet N, Lurz E, Kavallar A, Gonzales E, Jacquemin E, Bouligand J, Ebel N, Feinstein J, Siew S, Stormon M, Karpen S, Romero R, Jensen M, Jaramillo C, Squires J, Bedoyan S, Kelly D, Hartley J, Verkade H, Lee W, Lertudomphonwanit C, Fischer R, Lin H, Rock N, Mozer‐Glassberg Y, Roberts A, Evans H, Karnsakul W, Nebbia G, Wolters V, Valentino P, Bernabeu J, Aqul A, Arikan C, Tamara M, Busoms C, Sandahl T, Indolfi G, Zizzo A, Zellos A, Quiros‐Tejeira R, Santos‐Silva E, Schwarz K, Brecelj J, Sanchez M, Cavalieri M, Tzivinikos C, Wiecek S, Eshun J, Kerkar N, Mujawar Q, Önal Z, Gonçalves C, Garcia J, Alam S, Jimenez‐Rivera C, Bujanda L, Thompson R, Hansen B, Spinner N, Gilbert M, Kamath B, Group T. Phenotypic Divergence of JAG1‐ and NOTCH2‐Associated Alagille Syndrome & Disease‐Specific NOTCH2 Variant Classification Guidelines. Liver International 2025, 45: e70251. PMID: 40742203, PMCID: PMC12312628, DOI: 10.1111/liv.70251.Peer-Reviewed Original ResearchRecent advances in the management of pediatric cholestatic liver diseases
Mysore K, Cheng K, Suri L, Fawaz R, Mavis A, Kogan‐Liberman D, Mohammad S, Taylor S. Recent advances in the management of pediatric cholestatic liver diseases. Journal Of Pediatric Gastroenterology And Nutrition 2025, 80: 549-558. PMID: 39840645, PMCID: PMC11961318, DOI: 10.1002/jpn3.12462.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2024
Topiramate treatment of pediatric metabolic dysfunction–associated steatotic liver disease: A descriptive cohort study
Kohut T, Tou A, Carr E, Xanthakos S, Arce‐Clachar A, Fawaz R, Valentino P, Panganiban J, Mouzaki M. Topiramate treatment of pediatric metabolic dysfunction–associated steatotic liver disease: A descriptive cohort study. Journal Of Parenteral And Enteral Nutrition 2024, 49: 308-313. PMID: 39720872, DOI: 10.1002/jpen.2722.Peer-Reviewed Original ResearchPharmacological management of pediatric metabolic dysfunction‐associated steatotic liver disease
Jaoudeh R, Hartmann P, Olson O, Gupta O, Kumar S, Ibrahim S, Fawaz R, Aqul A, Hassan S. Pharmacological management of pediatric metabolic dysfunction‐associated steatotic liver disease. Journal Of Pediatric Gastroenterology And Nutrition 2024, 80: 14-24. PMID: 39526564, DOI: 10.1002/jpn3.12402.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2023
Event-free survival of maralixibat-treated patients with Alagille syndrome compared to a real-world cohort from GALA
Hansen B, Vandriel S, Vig P, Garner W, Mogul D, Loomes K, Piccoli D, Rand E, Jankowska I, Czubkowski P, Gliwicz-Miedzińska D, Gonzales E, Jacquemin E, Bouligand J, D’Antiga L, Nicastro E, Arnell H, Fischler B, Sokal É, Demaret T, Siew S, Stormon M, Karpen S, Romero R, Ebel N, Feinstein J, Roberts A, Evans H, Sundaram S, Chaidez A, Hardikar W, Shankar S, Fischer R, Lacaille F, Debray D, Lin H, Jensen M, Jaramillo C, Karthikeyan P, Indolfi G, Verkade H, Larson-Nath C, Quiros-Tejeira R, Valentino P, Rogalidou M, Dezsőfi A, Squires J, Schwarz K, Calvo P, Bernabeu J, Zizzo A, Nebbia G, Bulut P, Santos-Silva E, Fawaz R, Nastasio S, Karnsakul W, Tamara M, Busoms C, Kelly D, Sandahl T, Jimenez-Rivera C, Banales J, Mujawar Q, Li L, She H, Wang J, Kim K, Oh S, Sanchez M, Cavalieri M, Lee W, Hajinicolaou C, Lertudomphonwanit C, Waisbourd-Zinman O, Arikan C, Alam S, Carvalho E, Melere M, Eshun J, Önal Z, Desai D, Wiecek S, Pinto R, Wolters V, Garcia J, Beretta M, Kerkar N, Brecelj J, Rock N, Lurz E, Blondet N, Shah U, Thompson R, Kamath B, Group T. Event-free survival of maralixibat-treated patients with Alagille syndrome compared to a real-world cohort from GALA. Hepatology 2023, 79: 1279-1292. PMID: 38146932, PMCID: PMC11095900, DOI: 10.1097/hep.0000000000000727.Peer-Reviewed Original ResearchFood Insecurity and Pediatric Nonalcoholic Fatty Liver Disease Severity
Orkin S, Zhao X, Setchell K, Carr E, Arce-Clachar A, Bramlage K, Huang R, Fei L, Beck A, Fawaz R, Valentino P, Xanthakos S, Mouzaki M. Food Insecurity and Pediatric Nonalcoholic Fatty Liver Disease Severity. The Journal Of Pediatrics 2023, 265: 113818. PMID: 37931698, PMCID: PMC11108653, DOI: 10.1016/j.jpeds.2023.113818.Peer-Reviewed Original ResearchA quality improvement intervention to decrease the decline in renal function in pediatric liver transplant recipients
Batsis I, Elisofon S, Ferguson M, Jonas M, Kimball B, Lee C, Mitchell P, Fawaz R. A quality improvement intervention to decrease the decline in renal function in pediatric liver transplant recipients. Pediatric Transplantation 2023, 27: e14506. PMID: 36938904, DOI: 10.1111/petr.14506.Peer-Reviewed Original Research
2022
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study
Vandriel S, Li L, She H, Wang J, Gilbert M, Jankowska I, Czubkowski P, Gliwicz‐Miedzińska D, Gonzales E, Jacquemin E, Bouligand J, Spinner N, Loomes K, Piccoli D, D'Antiga L, Nicastro E, Sokal É, Demaret T, Ebel N, Feinstein J, Fawaz R, Nastasio S, Lacaille F, Debray D, Arnell H, Fischler B, Siew S, Stormon M, Karpen S, Romero R, Kim K, Baek W, Hardikar W, Shankar S, Roberts A, Evans H, Jensen M, Kavan M, Sundaram S, Chaidez A, Karthikeyan P, Sanchez M, Cavalieri M, Verkade H, Lee W, Squires J, Hajinicolaou C, Lertudomphonwanit C, Fischer R, Larson‐Nath C, Mozer‐Glassberg Y, Arikan C, Lin H, Bernabeu J, Alam S, Kelly D, Carvalho E, Ferreira C, Indolfi G, Quiros‐Tejeira R, Bulut P, Calvo P, Önal Z, Valentino P, Desai D, Eshun J, Rogalidou M, Dezsőfi A, Wiecek S, Nebbia G, Pinto R, Wolters V, Tamara M, Zizzo A, Garcia J, Schwarz K, Beretta M, Sandahl T, Jimenez‐Rivera C, Kerkar N, Brecelj J, Mujawar Q, Rock N, Busoms C, Karnsakul W, Lurz E, Santos‐Silva E, Blondet N, Bujanda L, Shah U, Thompson R, Hansen B, Kamath B, Group T. Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Hepatology 2022, 77: 512-529. PMID: 36036223, PMCID: PMC9869940, DOI: 10.1002/hep.32761.Peer-Reviewed Original Research
Clinical Trials
Current Trials
Wilson Disease Registry
IRB ID1609018429REGRoleSub InvestigatorPrimary Completion Date10/01/2022Recruiting ParticipantsGenderBothPrevalence of Carbohydrate Intolerance in Lean and Obese Children
IRB ID9909011190RoleSub InvestigatorPrimary Completion Date09/30/2025Recruiting ParticipantsGenderBothAge8 years - 18 years
Clinical Care
Overview
Rima Fawaz, MD, is the medical director of the Pediatric Liver Transplant Program and says the best part of her job is giving patients a new lease on life.
“It’s a happy field,” Dr. Fawaz says of transplant hepatology. “It’s truly the gift of life. In pediatric liver transplant, 60 to 70% of the causes are either inherited or something you are born with. Only a small fraction is something acquired, like from an infection. When we transplant, the outcomes are excellent with survival at 80% for patients 20 to 30 years later, which is astounding.”
Thanks to advances in anti-rejection medications, children who receive liver transplants today are able to live normal, healthy lives, Dr. Fawaz says. “Whereas it used to be about keeping them alive, now we are focused on long-term outcomes and finding the perfect balance of giving them just enough medication to prevent rejection, but also not harming any other organs from the medications,” she says.
In children, the main reason for liver transplant is biliary atresia, a congenital condition in which the bile ducts inside or outside of the liver do not develop properly. “This accounts for 40 to 50% of all liver transplants in pediatrics. The child cannot grow and life is so unhappy,” Dr. Fawaz says. “Then you transplant them, and you turn back time. Life returns. The kids typically do so well that we see them once or twice a year. It’s amazing.”
Dr. Fawaz is involved in several research efforts, including a study on acute liver failure funded by the National Institutes of Health.
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Polycystic Kidney Disease (PKD)
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