Adjunct Faculty
Adjunct Faculty are scientists or others who are employed outside of the school but have a specific, mutually beneficial role to Yale School of Medicine department programs.
Adjunct rank detailsRajesh Rajagopalan Tampi, MBBS, MS, DFAPA
Professor Adjunct, PsychiatryAbout
Research
Publications
2025
Neurobiology of Behavioral and Psychological Symptoms of Dementia A Focus on Agitation/Aggression, Apathy, and Psychosis
Tampi R, Joshi P, Zdanys K. Neurobiology of Behavioral and Psychological Symptoms of Dementia A Focus on Agitation/Aggression, Apathy, and Psychosis. Advances In Psychiatry And Behavioral Health 2025, 5: 129-137. DOI: 10.1016/j.ypsc.2025.01.002.Peer-Reviewed Original ResearchLecanemab for mild Alzheimer disease – is there a way forward?
Tampi R. Lecanemab for mild Alzheimer disease – is there a way forward? Drugs In Context 2025, 14: 1-6. PMID: 40078953, PMCID: PMC11900888, DOI: 10.7573/dic.2024-12-2.Peer-Reviewed Original Research
2024
A Review of Dextromethorphan-Quinidine for the Treatment of Agitation in Dementia.
Khan A, Murphy K, Tampi R. A Review of Dextromethorphan-Quinidine for the Treatment of Agitation in Dementia. The Primary Care Companion For CNS Disorders 2024, 26 PMID: 39546373, DOI: 10.4088/pcc.24nr03737.Peer-Reviewed Original ResearchConceptsRandomized Controlled TrialsFull-text reviewDextromethorphan-quinidineTreatment of agitationDementia-related agitationAPA PsycInfoCase reportCochrane CollaborationAbstracted dataDementiaTreatment settingsDuration of treatmentPatient diagnosisPatient populationSymptom responseTreatment doseEnglish languageQualitative analysisAuthor affiliationTreatment studiesPsycINFOSymptomsTreatmentDextromethorphanPatientsDexmedetomidine for agitation in dementia: Current data and future direction
Murphy K, Golden J, Tampi R. Dexmedetomidine for agitation in dementia: Current data and future direction. Journal Of The American Geriatrics Society 2024, 73: 552-557. PMID: 39295447, DOI: 10.1111/jgs.19196.Peer-Reviewed Original ResearchConceptsPrevalence of dementiaDementia-relatedHospital deliriumPsychological symptomsDementiaCochrane DatabaseEnglish-language journalsBPSDStudy typeLanguage journalsDeliriumControlled studiesSample sizeBipolar disorderSymptomsRoute of administrationCochraneHospitalEfficacious optionPubMedEffective treatmentPrevalenceIs there evidence for using ketamine among individuals with dementia?
Kapoor A, Estevez T, Chan C, Yamagata N, Doumlele K, Tampi R. Is there evidence for using ketamine among individuals with dementia? Journal Of International Medical Research 2024, 52: 03000605241258473. PMID: 38907362, PMCID: PMC11193926, DOI: 10.1177/03000605241258473.Peer-Reviewed Original ResearchConceptsBehavioral disturbancesNon-English languageTreatment of depressionDementiaInclusion criteriaNarrative reviewNo significant adverse effectsDepressionAgitation associated with dementiaProspective studyAcute agitationSubcutaneous ketamineSignificant adverse effectsIndividualsTreat behavioral disturbancesCase reportElectroconvulsive therapyS-ketamineClinical useAnimal studiesBipolar Disorders
Tampi R, Tampi D. Bipolar Disorders. 2024, 139-149. DOI: 10.1007/978-3-031-55711-8_10.Peer-Reviewed Original ResearchOlder age bipolar disorderEarly-onset bipolar disorderCases of bipolar disorderBipolar disorderElectroconvulsive therapyFamily history of mood disordersHistory of mood disorderInpatient psychiatric hospitalizationTreatment of individualsMental health servicesPsychosocial treatmentsMood disordersCompared to age-matched controlsPsychiatric hospitalAge-matched controlsAdjunctive treatmentTreated individualsDisordersMedication classesHealth servicesFamily historyIndividualsNeurological disordersCerebrovascular diseaseRefractory casesBehavioral and Psychological Symptoms of Major Neurocognitive Disorders
Tampi R, Tampi D. Behavioral and Psychological Symptoms of Major Neurocognitive Disorders. 2024, 75-89. DOI: 10.1007/978-3-031-55711-8_6.Peer-Reviewed Original ResearchNon-pharmacological interventionsTreatment of BPSDNeuropsychiatric InventoryAssociated with greater caregiver burdenPsychological symptomsNon-pharmacologicalAssessment of BPSDGreater caregiver burdenStandardized assessment toolsSymptoms of BPSDNeurocognitive disordersMajor neurocognitive disorderMental status examinationCaregiver burdenPharmacological interventionsBPSDNoncognitive symptomsAssessment toolDementiaInterventionPharmacological managementPhysical examinationIncreased morbidityComprehensive assessmentSymptomsNicotine Use Disorder
Khan A, Tampi R, Tampi D. Nicotine Use Disorder. 2024, 227-239. DOI: 10.1007/978-3-031-55711-8_16.Peer-Reviewed Original ResearchOlder adultsNicotine use disorderCombination of pharmacotherapyCessation interventionsNicotine replacement therapyRelapse preventionUse disorderBehavioral interventionsRelapsing conditionQuit smokingPopulation of older adultsSmoking cessationFood and Drug AdministrationNicotineReplacement therapyAdultsDrug AdministrationEffective cessation interventionsTobacco useInterventionRelapseBupropionVareniclinePharmacotherapyCessationDepressive Disorders
Tampi R, Tampi D. Depressive Disorders. 2024, 127-138. DOI: 10.1007/978-3-031-55711-8_9.Peer-Reviewed Original ResearchTreatment of depressionRepetitive transcranial magnetic stimulationDepressive disorderElectroconvulsive therapyComprehensive mental status examinationTreatment of depressive disordersOlder adultsBenefits of ketamineMental status examinationDiagnosis of depressionPsychotic featuresNeuropsychological testsHomicidal behaviorTranscranial magnetic stimulationCatatonic featuresCollaborative care approachDepressionTreatment responseDisordersMagnetic stimulationRefractory to other treatmentsScreening laboratory studiesOlder individualsAdultsCare approachThe Utilization of Preoperative Steroids Safely Decreases the Risk of Postoperative Delirium in Geriatric Patients After Hip Fracture Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Baumann A, Talaski G, Uhler M, Anastasio A, Walley K, Pean C, Tampi R, Farivar M. The Utilization of Preoperative Steroids Safely Decreases the Risk of Postoperative Delirium in Geriatric Patients After Hip Fracture Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Journal Of Orthopaedic Trauma 2024, 38: e182-e190. PMID: 38300234, DOI: 10.1097/bot.0000000000002781.Peer-Reviewed Original ResearchConceptsRisk of postoperative deliriumHip fracture surgeryAll-cause infectionPreoperative steroidsFracture surgeryRandomized Controlled TrialsPostoperative deliriumSurgical interventionHip fractureGeriatric patientsMeta-analysis of randomized controlled trialsRandomized controlled trial of patientsControlled TrialsPreoperative steroid administrationControlled trials of patientsIncidence of postoperative deliriumDescription of levels of evidenceMeta-analysisTrial of patientsOutcomes of geriatric patientsTherapeutic Level IIPrevent postoperative deliriumSystematic reviewLevel of evidenceAbsolute risk difference
Academic Achievements & Community Involvement
News
News
- May 22, 2024
Tampi Edits 'Treatment of Psychiatric Disorders Among Older Adults'
- February 15, 2024
Tampi Chosen to Receive AAGP Diversity Award
- January 03, 2024Source: Psychiatric Times
Geriatric Psychiatry in the U.S.