Nicholas S. Moore, MD
Assistant Professor of Therapeutic RadiologyAbout
Research
Publications
2025
Prediction of Lymph Node Metastasis in Non–Small Cell Lung Carcinoma Using Primary Tumor Somatic Mutation Data
Lee V, Moore N, Doyle J, Hicks D, Oh P, Bodofsky S, Hossain S, Patel A, Aneja S, Homer R, Park H. Prediction of Lymph Node Metastasis in Non–Small Cell Lung Carcinoma Using Primary Tumor Somatic Mutation Data. JCO Clinical Cancer Informatics 2025, 9: e2400303. PMID: 40446175, DOI: 10.1200/cci-24-00303.Peer-Reviewed Original ResearchThis study investigates machine learning models using tumor genetic data to predict lymph node metastasis in lung cancer, showing improved accuracy over traditional methods and more potential for personalized treatment.
2024
Radioresistant Pulmonary Oligometastatic and Oligoprogressive Lesions From Nonlung Primaries: Impact of Histology and Dose-Fractionation on Local Control After Radiation Therapy
Verma N, Laird J, Moore N, Hayman T, Housri N, Peters G, Knowlton C, Jairam V, Campbell A, Park H. Radioresistant Pulmonary Oligometastatic and Oligoprogressive Lesions From Nonlung Primaries: Impact of Histology and Dose-Fractionation on Local Control After Radiation Therapy. Advances In Radiation Oncology 2024, 9: 101500. PMID: 38699671, PMCID: PMC11063223, DOI: 10.1016/j.adro.2024.101500.Peer-Reviewed Original ResearchIntegrative Analysis of Germline Rare Variants in Clear and Non–clear Cell Renal Cell Carcinoma
Han S, Camp S, Chu H, Collins R, Gillani R, Park J, Bakouny Z, Ricker C, Reardon B, Moore N, Kofman E, Labaki C, Braun D, Choueiri T, AlDubayan S, Van Allen E. Integrative Analysis of Germline Rare Variants in Clear and Non–clear Cell Renal Cell Carcinoma. European Urology Open Science 2024, 62: 107-122. PMID: 38496821, PMCID: PMC10940785, DOI: 10.1016/j.euros.2024.02.006.Peer-Reviewed Original Research
2023
Recombinant human DNase-I improves acute respiratory distress syndrome via neutrophil extracellular trap degradation
Jarrahi A, Khodadadi H, Moore N, Lu Y, Awad M, Salles E, Vaibhav K, Baban B, Dhandapani K. Recombinant human DNase-I improves acute respiratory distress syndrome via neutrophil extracellular trap degradation. Journal Of Thrombosis And Haemostasis 2023, 21: 2473-2484. PMID: 37196848, PMCID: PMC10185489, DOI: 10.1016/j.jtha.2023.04.044.Peer-Reviewed Original ResearchInflammaging, cellular senescence, and cognitive aging after traumatic brain injury
Lu Y, Jarrahi A, Moore N, Bartoli M, Brann D, Baban B, Dhandapani K. Inflammaging, cellular senescence, and cognitive aging after traumatic brain injury. Neurobiology Of Disease 2023, 180: 106090. PMID: 36934795, PMCID: PMC10763650, DOI: 10.1016/j.nbd.2023.106090.Peer-Reviewed Original ResearchBladder Cancer Radiation Oncology of the Future: Prognostic Modelling, Radiomics, and Treatment Planning With Artificial Intelligence
Moore N, McWilliam A, Aneja S. Bladder Cancer Radiation Oncology of the Future: Prognostic Modelling, Radiomics, and Treatment Planning With Artificial Intelligence. Seminars In Radiation Oncology 2023, 33: 70-75. PMID: 36517196, DOI: 10.1016/j.semradonc.2022.10.009.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2022
Comparison of Pulmonary Toxicity after Total Body Irradiation- and Busulfan-Based Myeloablative Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients
Liu K, Poux N, Shin K, Moore N, Chen Y, Margossian S, Whangbo J, Duncan C, Lehmann L, Marcus K. Comparison of Pulmonary Toxicity after Total Body Irradiation- and Busulfan-Based Myeloablative Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients. Transplantation And Cellular Therapy 2022, 28: 502.e1-502.e12. PMID: 35623615, PMCID: PMC11075968, DOI: 10.1016/j.jtct.2022.05.028.Peer-Reviewed Original ResearchRapid expansion and extinction of antibiotic resistance mutations during treatment of acute bacterial respiratory infections
Chung H, Merakou C, Schaefers M, Flett K, Martini S, Lu R, Blumenthal J, Webster S, Cross A, Al Ahmar R, Halpin E, Anderson M, Moore N, Snesrud E, Yu H, Goldberg J, O’Toole G, McGann P, Stam J, Hinkle M, McAdam A, Kishony R, Priebe G. Rapid expansion and extinction of antibiotic resistance mutations during treatment of acute bacterial respiratory infections. Nature Communications 2022, 13: 1231. PMID: 35264582, PMCID: PMC8907320, DOI: 10.1038/s41467-022-28188-w.Peer-Reviewed Original Research
2021
Integrating molecular profiles into clinical frameworks through the Molecular Oncology Almanac to prospectively guide precision oncology
Reardon B, Moore N, Moore N, Kofman E, AlDubayan S, Cheung A, Conway J, Elmarakeby H, Imamovic A, Kamran S, Keenan T, Keliher D, Konieczkowski D, Liu D, Mouw K, Park J, Vokes N, Dietlein F, Van Allen E. Integrating molecular profiles into clinical frameworks through the Molecular Oncology Almanac to prospectively guide precision oncology. Nature Cancer 2021, 2: 1102-1112. PMID: 35121878, PMCID: PMC9082009, DOI: 10.1038/s43018-021-00243-3.Peer-Reviewed Original Research
2020
Detection of Pathogenic Variants With Germline Genetic Testing Using Deep Learning vs Standard Methods in Patients With Prostate Cancer and Melanoma
AlDubayan S, Conway J, Camp S, Witkowski L, Kofman E, Reardon B, Han S, Moore N, Elmarakeby H, Salari K, Choudhry H, Al-Rubaish A, Al-Sulaiman A, Al-Ali A, Taylor-Weiner A, Van Allen E. Detection of Pathogenic Variants With Germline Genetic Testing Using Deep Learning vs Standard Methods in Patients With Prostate Cancer and Melanoma. JAMA: The Journal Of The American Medical Association 2020, 324: 1957-1969. PMID: 33201204, PMCID: PMC7672519, DOI: 10.1001/jama.2020.20457.Peer-Reviewed Original Research
Clinical Care
Overview
Nicholas S. Moore, MD, is a radiation oncologist specializing in therapeutic radiology. He focuses on treating central nervous system tumors in both adults and children, as well as managing cancers of the genitourinary system, head and neck, gastrointestinal tract, and blood. He utilizes advanced radiation techniques to target these malignancies.
As an assistant professor of therapeutic radiology at Yale School of Medicine, Dr. Moore is involved in research that applies artificial intelligence to enhance the precision and effectiveness of cancer treatments.
Dr. Moore earned his medical degree from Harvard Medical School, completing his internship in internal medicine at Beth Israel Deaconess Medical Center. He pursued residency training in therapeutic radiology at Yale New Haven Hospital.
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Therapeutic Radiology
35 Park St, LL
New Haven, CT 06519
United States
Locations
Hunter Building
Academic Office
15 York Street, Rm 138
New Haven, CT 06510
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