Neill Epperson, MD
Director, Yale Program For Women’s Reproductive Behavioral Health (WRBH)About
Research
Publications
2025
Psychiatric symptoms on the ovarian hormone roller-coaster.
Comasco E, Epperson C, Kulkarni J. Psychiatric symptoms on the ovarian hormone roller-coaster. The British Journal Of Psychiatry 2025, 1-2. PMID: 40528482, DOI: 10.1192/bjp.2025.10298.Peer-Reviewed Original ResearchRefugee and Asylum Seeker Child and Adolescent Mental Health: A Systematic Review of Racial, Ethnic, and Contextual Disparities
Ali D, Olstein B, Vargas L, Hale E, Adi A, Savin D, Epperson C. Refugee and Asylum Seeker Child and Adolescent Mental Health: A Systematic Review of Racial, Ethnic, and Contextual Disparities. American Journal Of Orthopsychiatry 2025 PMID: 40504633, DOI: 10.1037/ort0000858.Peer-Reviewed Original ResearchSystematic reviewMental healthUnderuse of careMental health outcomesAdolescent mental health outcomesPreferred Reporting ItemsCare accessAPA PsycInfoHealth outcomesWeb of Science databasesAsylum-seeking populationReporting ItemsSociostructural factorsContextual disparitiesCareInclusion criteriaDisparitiesHealthAdolescent populationScience databasesAcculturative stressEthnic groupsInvestigated childrenAccess of refugeesOutcomesWhen the Bough Breaks: Are We Ever Going to Prevent Childhood Adversity?
Epperson C. When the Bough Breaks: Are We Ever Going to Prevent Childhood Adversity? American Journal Of Psychiatry 2025, 182: 322-325. PMID: 40165554, DOI: 10.1176/appi.ajp.20250121.Peer-Reviewed Original ResearchThe Trifecta of Industry, Academic, and Health System Partnership to Improve Mental Health Care Through Smartphone-Based Remote Patient Monitoring: Development and Usability Study
Epperson C, Davis R, Dempsey A, Haller H, Kupfer D, Love T, Villarreal P, Matthews M, Moore S, Muller K, Schneck C, Scott J, Zane R, Frank E. The Trifecta of Industry, Academic, and Health System Partnership to Improve Mental Health Care Through Smartphone-Based Remote Patient Monitoring: Development and Usability Study. JMIR Formative Research 2025, 9: e57624. PMID: 39773396, PMCID: PMC11751643, DOI: 10.2196/57624.Peer-Reviewed Original ResearchConceptsDigital mental health technologiesMental health careMental health technologiesMental health crisisHealth systemHealth careElectronic health record adaptationsHealth technologiesPatients' mental health statusClinic visitsMental health care providersHealth system partnershipsHealth care providersMental health statusElectronic health recordsMental health treatmentMonitoring patient symptomsHealth crisisPsychiatric outpatient clinicPatients' self-ratingsRemote patient monitoringCare providersDepressive disorderPatient experienceHealth records
2024
Field Notes from the Border: Lessons Learned in Conducting Mental Health Research Involving Newly Arrived Latinx Immigrants as Study Participants
Vargas L, Ariefdjohan M, Page C, Meisel Z, Ulrich C, Alegría M, Pimentel N, Epperson C, Richmond T. Field Notes from the Border: Lessons Learned in Conducting Mental Health Research Involving Newly Arrived Latinx Immigrants as Study Participants. Journal Of Immigrant And Minority Health 2024, 27: 181-189. PMID: 39503832, PMCID: PMC11781956, DOI: 10.1007/s10903-024-01643-0.Peer-Reviewed Original ResearchPublic health researchLatinx immigrantsImmigrant populationHealth researchCommunity partnersParticipant consentStudy participantsVulnerable populationsData collection proceduresStudy populationField notesResearch protocolParticipantsUnique issuesBest practicesCultural fluencyEthical considerationsCollection proceduresUS southern borderPopulationLatinxUnique perspectiveStress increases sperm respiration and motility in mice and men
Moon N, Morgan C, Marx-Rattner R, Jeng A, Johnson R, Chikezie I, Mannella C, Sammel M, Epperson C, Bale T. Stress increases sperm respiration and motility in mice and men. Nature Communications 2024, 15: 7900. PMID: 39261485, PMCID: PMC11391062, DOI: 10.1038/s41467-024-52319-0.Peer-Reviewed Original ResearchConceptsEpididymal epithelial cellsIncreased mitochondrial respirationIn vitro stress modelsCells secrete extracellular vesiclesSperm RNASperm respirationMouse spermSperm maturationDNA regionsSperm functionTranslational signaling pathwaysSperm motilitySemen qualitySpermMitochondrial respirationMetabolic pathwaysSignaling pathwayEnvironmental stressorsExtracellular vesiclesHuman cohort studiesEpithelial cellsMotilityCellular mechanismsEmbryo developmentCohort studyExtortion experiences of recent adult immigrants from Latin America: self-reported prevalence, associated costs, and current mental health
Vargas L, Epperson C, Richmond T, Sharif S, Berkowitz L, Giano Z, Hargarten S, Ungar M, Weigend-Vargas E, Sakai J. Extortion experiences of recent adult immigrants from Latin America: self-reported prevalence, associated costs, and current mental health. Injury Epidemiology 2024, 11: 43. PMID: 39238066, PMCID: PMC11376018, DOI: 10.1186/s40621-024-00524-2.Peer-Reviewed Original ResearchLatin AmericaLatinx immigrantsPost-traumatic stress disorderMental healthUS southern borderCurrent mental healthLatinx migrantsMigrant experienceImmigration officialsImmigrant adultsAdult immigrantsImmigrantsExtortionSeverity of post-traumatic stress disorderLatinLatinxViolencePerpetratorsSouthern borderSelf-reported prevalenceStress disorderSignificant stressorsUSAmericaAssociated with negative effectsMaternal adverse childhood experiences and infant visual-limbic white matter development
Demers C, Hankin B, Haase M, Todd E, Hoffman M, Epperson C, Styner M, Davis E. Maternal adverse childhood experiences and infant visual-limbic white matter development. Journal Of Affective Disorders 2024, 367: 49-57. PMID: 39191307, DOI: 10.1016/j.jad.2024.08.146.Peer-Reviewed Original ResearchMaternal adverse childhood experiencesAdverse childhood experiencesInferior longitudinal fasciculusFractional anisotropyLongitudinal fasciculusChildhood experiencesLeft inferior longitudinal fasciculusStructural magnetic resonance imagingPredictors of mental healthVisual processing networksNo group differencesExploratory analysisChildhood questionnaireEarly life adversity exposuresWhite matter microstructureMother-infant dyadsFollow-up analysisCognitive circuitsPreliminary supportNeural circuit developmentInfant brain developmentMagnetic resonance imagingGroup differencesSensory processingIntergenerational riskTrends in Individual Career Development Awards from National Institutes of Health to Physicians in Departments of Psychiatry (2013–2022)
Sakai J, Epperson C, Panchal Z, Ali D, Singhal S, Mikulich-Gilbertson S. Trends in Individual Career Development Awards from National Institutes of Health to Physicians in Departments of Psychiatry (2013–2022). Academic Psychiatry 2024, 49: 75-79. PMID: 39174721, DOI: 10.1007/s40596-024-02027-0.Peer-Reviewed Original ResearchDepartment of PsychiatryCareer development awardsDevelopment AwardNon-physician facultyNational InstituteNational Institutes of HealthNational Institutes of Health (NIHInstitutes of HealthPhysiciansPsychiatry facultyObjectiveThe authorsPsychiatryConclusionsThe numberDepartmentLinear regressionFacultyNationalMethodsDataHealthEstimated slopePsychiatristsLack of growthTreating new-onset cognitive complaints after risk-reducing salpingo-oophorectomy: A randomized controlled crossover trial of lisdexamfetamine
Metcalf C, Page C, Stocker B, Johnson R, Duffy K, Sammel M, Loughead J, Epperson C. Treating new-onset cognitive complaints after risk-reducing salpingo-oophorectomy: A randomized controlled crossover trial of lisdexamfetamine. Gynecologic Oncology 2024, 190: 62-69. PMID: 39146756, PMCID: PMC11702344, DOI: 10.1016/j.ygyno.2024.07.689.Peer-Reviewed Original ResearchRisk-reducing salpingo-oophorectomySelf-report measures of executive functionBrown Attention Deficit Disorder ScaleMeasures of executive functionMeasures of cognitive functionWorking memory performanceExecutive function difficultiesMeasures of attentionSelf-report measuresTrial completion ratesGenetically at-riskRandomized controlled crossover trialAttention/working memoryExecutive functionWorking memoryDisorder ScaleMemory performanceSustained attentionCognitive complaintsCognitive tasksLisdexamfetamineCognitive functionActive medicationTotal scoreFunctional difficulties