Nai Yang Yeat, PhD
Postdoctoral AssociateAbout
Research
Publications
2025
Extracellular vesicles: biogenesis mechanism and impacts on tumor immune microenvironment.
Yeat NY, Chen RH. Extracellular vesicles: biogenesis mechanism and impacts on tumor immune microenvironment. J Biomed Sci 2025, 32: 85. PMID: 40908470, DOI: 10.1186/s12929-025-01182-2.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsBro1 proteins determine tumor immune evasion and metastasis by controlling secretion or degradation of multivesicular bodies.
Yeat NY, Liu LH, Chang YH, Lai CP, Chen RH. Bro1 proteins determine tumor immune evasion and metastasis by controlling secretion or degradation of multivesicular bodies. Dev Cell 2025, 60: 2114-2130.e9. PMID: 40185104, DOI: 10.1016/j.devcel.2025.03.008.Peer-Reviewed Original Research
2023
PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target.
Singh S, Yeat NY, Wang YT, Lin SY, Kuo IY, Wu KP, Wang WJ, Wang WC, Su WC, Wang YC, Chen RH. PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target. Cell Death Dis 2023, 14: 671. PMID: 37821451, DOI: 10.1038/s41419-023-06201-4.Peer-Reviewed Original ResearchTRABID inhibition activates cGAS/STING-mediated anti-tumor immunity through mitosis and autophagy dysregulation.
Chen YH, Chen HH, Wang WJ, Chen HY, Huang WS, Kao CH, Lee SR, Yeat NY, Yan RL, Chan SJ, Wu KP, Chen RH. TRABID inhibition activates cGAS/STING-mediated anti-tumor immunity through mitosis and autophagy dysregulation. Nat Commun 2023, 14: 3050. PMID: 37237031, DOI: 10.1038/s41467-023-38784-z.Peer-Reviewed Original Research
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600 West Campus Drive, Fl 3, Rm 319
West Haven, CT 06516