Michael Nanna, MD, MHS, FSCAI, FACC
Assistant Professor of Internal Medicine (Cardiovascular Medicine)DownloadHi-Res Photo
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Appointments
Cardiovascular Medicine
Primary
Contact Info
Cardiovascular Medicine
333 Cedar St.
New Haven, CT 06510
United States
About
Titles
Assistant Professor of Internal Medicine (Cardiovascular Medicine)
Biography
Dr. Nanna is an Interventional Cardiologist specializing in coronary interventions, with a focus on the care of older adults living with multiple chronic conditions. Dr. Nanna graduated Stony Brook University School of Medicine as a member of both the Alpha Omega Alpha and the Arnold P. Gold Foundation honor societies. He completed his training in internal medicine and served as a chief resident at Yale New Haven Hospital before training in Cardiology and Interventional Cardiology at Duke University Medical Center. In addition, he completed a Master of Health Sciences in Clinical Research degree through the Clinical Research Training Program at Duke University School of Medicine.
His research interests center around improving risk prediction, treatment utilization and shared decision-making for older adults at risk for or living with cardiovascular disease. He is the recipient of several awards including a GEMSSTAR (Grants for Early Medical/Surgical Specialists’ Transition to Aging Research) award from the NIH National Institute on Aging to address the medical needs of older adult patients at high risk for cardiovascular disease and dementia, as well as a geriatric cardiology professional development award from the American College of Cardiology Foundation supported by the George F. and Ann Harris Bellows Foundation. In collaboration with the Yale Pepper Center, he is the national PI for the LIVEBETTER trial, a randomized trial of anti-anginal therapies in older adults with stable ischemic heart disease and multiple chronic conditions funded by the Patient-Centered Outcomes Research Institute (PCORI). Most recently, he was selected as a Beeson Scholar by the National Institute on Aging, receiving a K76 award to investigate the treatment effects of cardiovascular medications on cognitive trajectory in older adults. Dr. Nanna currently serves as an Associate Editor at the American Heart Journal & JACC Advances. He has served as a reviewer for a number of scholarly journals including JAMA, JACC, and Circulation.
Appointments
Cardiovascular Medicine
Assistant ProfessorPrimary
Other Departments & Organizations
Education & Training
- Fellowship, Interventional Cardiology
- Duke University Medical Center (2021)
- MHS
- Duke University School of Medicine, Clinical Research (2020)
- Cardiovascular Research Fellowship
- Duke University/Duke Clinical Research Institute (2020)
- Fellowship, Cardiology
- Duke University Medical Center (2019)
- Chief Resident
- Yale School of Medicine (2016)
- Internship/Residency, Internal Medicine
- Yale New Haven Hospital (2015)
- MD
- Stony Brook School of Medicine (2012)
- BA
- Colgate University (2008)
Research
Overview
Medical Subject Headings (MeSH)
Cardiology
ORCID
0000-0001-5745-1636
Research at a Glance
Yale Co-Authors
Frequent collaborators of Michael Nanna's published research.
Publications Timeline
A big-picture view of Michael Nanna's research output by year.
Research Interests
Research topics Michael Nanna is interested in exploring.
Dae Yong Park, MD, MSCI
Sarwat Chaudhry, MD
Mary Geda, BSN, MSN, RN
Harlan Krumholz, MD, SM
Carlos Mena-Hurtado, MD, FACC, FSCAI, FAHA
Marc Samsky, MD, FACC
136Publications
1,326Citations
Publications
2024
Oral anticoagulants or antiplatelets for cryptogenic stroke: a systematic review and meta-analysis
Chi K, Song J, Zarif T, Chiang C, Lee P, Chang Y, Nanna M, Nanna M. Oral anticoagulants or antiplatelets for cryptogenic stroke: a systematic review and meta-analysis. European Heart Journal 2024, 45: ehae666.2309. DOI: 10.1093/eurheartj/ehae666.2309.Peer-Reviewed Original ResearchConceptsLeft atrial diameterRelevant randomized controlled trialsPatent foramen ovaleNAVIGATE ESUS trialOral anticoagulantsOral anticoagulant useRecurrent ischemic strokeCryptogenic strokeIschemic strokeMeta-analysisSubgroup analysisESUS patientsHazard ratioSafety of oral anticoagulantsInternational Society of ThrombosisSociety of ThrombosisOptimal antithrombotic strategyAtrial cardiopathyDiagnostic work-upRE-SPECT ESUSElectronic databases of PubMedCryptogenic stroke patientsSources of cardioembolismRandom-effects meta-analysisSystematic reviewMortality effects of beta-blockers on myocardial infarction in patients without reduced ejection fraction or heart failure in the contemporary reperfusion era : a systematic review and meta-analysis
Y K, Lee P, Chowdhury I, Schwartz R, Kang Y, Mangalesh S, Babapour G, Akman Z, Chang Y, Song J, Lessa Y, Damluji A, Nanna M, Nanna M. Mortality effects of beta-blockers on myocardial infarction in patients without reduced ejection fraction or heart failure in the contemporary reperfusion era : a systematic review and meta-analysis. European Heart Journal 2024, 45: ehae666.1640. DOI: 10.1093/eurheartj/ehae666.1640.Peer-Reviewed Original ResearchConceptsRandomized controlled trialsReduced ejection fractionBeta-blockersEjection fractionHeart failureMortality benefitReduced EFMeta-regressionEF patientsPreserved EFBB usersReperfusion eraMeta-analysisSubgroup analysisSystematic reviewPost-MIPost-MI careEffect of beta-blockersIncreased all-cause mortalityHistory of HFEvent-free periodAll-cause mortalityTemporal trendsStudy inclusion periodModern randomized controlled trialsPrognostic Value of Cardiovascular Biomarkers
Mangalesh S, Nanna M. Prognostic Value of Cardiovascular Biomarkers. JAMA 2024, 332: 1302-1303. PMID: 39292479, DOI: 10.1001/jama.2024.16522.Peer-Reviewed Original ResearchAltmetricMeSH KeywordsValidating the PREVENT Equations—A Contemporary Update to Cardiovascular Risk Assessment
Mangalesh S, Nanna M. Validating the PREVENT Equations—A Contemporary Update to Cardiovascular Risk Assessment. JAMA Network Open 2024, 7: e2438284. PMID: 39392636, DOI: 10.1001/jamanetworkopen.2024.38284.Peer-Reviewed Original ResearchAltmetricBeta-blockers for secondary prevention following myocardial infarction in patients without reduced ejection fraction or heart failure: an updated meta-analysis
Chi K, Lee P, Chowdhury I, Akman Z, Mangalesh S, Song J, Satish V, Babapour G, Kang Y, Schwartz R, Chang Y, Borkowski P, Nanna M, Damluji A, Nanna M. Beta-blockers for secondary prevention following myocardial infarction in patients without reduced ejection fraction or heart failure: an updated meta-analysis. European Journal Of Preventive Cardiology 2024, zwae298. PMID: 39298680, DOI: 10.1093/eurjpc/zwae298.Peer-Reviewed Original ResearchAltmetricConceptsReduced ejection fractionBeta-blockersEjection fractionHeart failureMortality benefitBB useReduced EFCV mortalityPost-MIRandom-effects meta-analysisMeta-analysisHistory of HFAll-cause mortalityTemporal trendsPrespecified subgroup analysesEvent-free periodCardiovascular (CVIncreased CV mortalityStudy inclusion periodPost-myocardial infarctionContemporary dataAssociated with detrimental effectsNon-significant trendSecondary preventionBB usersComparative Analysis of PCI Strategies in Aortic Stenosis Patients Undergoing TAVI: A Systematic Review and Network Meta‐Analysis
Fallahtafti P, Soleimani H, Ebrahimi P, Ghaseminejad‐Raeini A, Karimi E, Shirinezhad A, Sabri M, Mehrani M, Taheri H, Siegel R, Shah N, Nanna M, Hakim D, Hosseini K. Comparative Analysis of PCI Strategies in Aortic Stenosis Patients Undergoing TAVI: A Systematic Review and Network Meta‐Analysis. Clinical Cardiology 2024, 47: e24324. PMID: 39054901, PMCID: PMC11272956, DOI: 10.1002/clc.24324.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsTranscatheter aortic valve implantationCoronary artery diseasePercutaneous coronary interventionIn-hospital mortalityNetwork meta-analysisMyocardial infarctionAortic stenosisAssociated with worse 30-day outcomeMeta-analysisIncreased risk of 1-year mortalityAssociated with higher 1-year mortalityRisk of 1-year mortalitySevere aortic stenosisFrequentist network meta-analysisRates of myocardial infarctionPercutaneous coronary intervention timeTime of revascularizationAortic valve implantationSevere ASNo significant differencePacemaker implantationPost-TAVIValve implantationPatient characteristicsArtery diseaseTrend of Controlled Low-Density Lipoprotein Cholesterol in Older Adults With a History of Myocardial Infarction or Stroke
Park D, Jamil Y, Frampton J, Al Damluji A, Nanna M. Trend of Controlled Low-Density Lipoprotein Cholesterol in Older Adults With a History of Myocardial Infarction or Stroke. JACC Advances 2024, 3: 101091. PMID: 39099776, PMCID: PMC11294686, DOI: 10.1016/j.jacadv.2024.101091.Peer-Reviewed Original ResearchAltmetricAssociation Between Body Mass Index, Testing Performance And Clinical Outcomes In Patients With Stable Chest Pain: Insights From The PRECISE (Prospective Randomized Trial Of The Optimal Evaluation Of Cardiac Symptoms And Revascularization) Trial
Ferencik M, Vemulapalli S, Nanna M, Kelsey M, Mark D, Leipsic J, Ng N, Maurovich-Horvat P, Mullen S, Rogers C, Udelson J, Douglas P. Association Between Body Mass Index, Testing Performance And Clinical Outcomes In Patients With Stable Chest Pain: Insights From The PRECISE (Prospective Randomized Trial Of The Optimal Evaluation Of Cardiac Symptoms And Revascularization) Trial. Journal Of Cardiovascular Computed Tomography 2024, 18: s38. DOI: 10.1016/j.jcct.2024.05.087.Peer-Reviewed Original ResearchAltmetricPercutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis
Reddy R, Howard J, Jamil Y, Madhavan M, Nanna M, Lansky A, Leon M, Ahmad Y. Percutaneous Coronary Revascularization Strategies After Myocardial Infarction A Systematic Review and Network Meta-Analysis. Journal Of The American College Of Cardiology 2024, 84: 276-294. PMID: 38986670, DOI: 10.1016/j.jacc.2024.04.051.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsRelative riskCardiovascular mortalityMyocardial infarctionMultivessel coronary artery diseaseAll-cause mortalityAdverse cardiac eventsST-segment elevation myocardial infarctionComplete revascularizationCoronary artery diseaseBayesian network meta-analysesMortality reductionA systematic reviewNetwork meta-analysesElevation myocardial infarctionSystematic reviewMeta-analysesCardiac eventsArtery diseasePrimary outcomeNetwork meta-analysisRevascularization strategyMeta-analysisHead-to-head trialsCoronary revascularization strategyAcute kidney injuryRepresentation of Older Adults in the ACC/AHA/SCAI Guideline for Coronary Artery Revascularization
Jamil Y, Sibindi C, Park D, Frampton J, Damluji A, Nanna M. Representation of Older Adults in the ACC/AHA/SCAI Guideline for Coronary Artery Revascularization. JAMA Network Open 2024, 7: e2421547. PMID: 38995647, PMCID: PMC11245718, DOI: 10.1001/jamanetworkopen.2024.21547.Peer-Reviewed Original ResearchAltmetric
Clinical Trials
Current Trials
LIVEBETTER (a trial comparing the effectiveness and tolerability of medications in older adults with stable angina and multiple chronic conditions)
HIC ID2000034470RolePrincipal InvestigatorPrimary Completion Date05/30/2027Recruiting Participants
Academic Achievements & Community Involvement
activity American Heart Journal
Journal ServiceAssociate EditorDetails08/09/2021 - Presentactivity JAMA
Journal ServiceReviewerDetails12/03/2019 - Presentactivity JAMA Internal Medicine
Journal ServiceReviewerDetails08/05/2020 - Presentactivity JAMA Cardiology
Journal ServiceReviewerDetails05/20/2020 - Presentactivity JACC
Journal ServiceReviewerDetails01/05/2020 - Present
Clinical Care
Overview
Clinical Specialties
Interventional Cardiology; Cardiovascular Medicine
Fact Sheets
Heart Attack (Myocardial Infarction)
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News
- November 07, 2024Source: The New York Times
8 Factors That Can Raise Your Heart Disease Risk
- November 05, 2024
Yale Researchers at American Heart Association Scientific Session 2024
- October 24, 2024
New Analytics Center for Cardiovascular Medicine
- May 20, 2024Source: The Washington Post
Heart checkups you should have and those you can probably skip
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Cardiovascular Medicine
333 Cedar St.
New Haven, CT 06510
United States
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