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Matthew Vesely, MD, PhD

Assistant Professor of Dermatology

Contact Information

Matthew Vesely, MD, PhD

Patient Care Location

Lab Location

  • West Campus Molecular Innovations Center
    600 West Campus Drive
    West Haven, CT 06516

Office Location

  • Hunter Building
    15 York Street, Rm HRT 603B
    New Haven, CT 06510

Mailing Address

  • Dermatology

    333 Cedar Street, LMP 5040, PO Box 208059

    New Haven, CT 06520-8059

    United States



I am a physician-scientist who has trained in immunology, molecular biology, genetics and clinical dermatology. My overall career goal as a physician-scientist are to integrate fundamental immunology with clinical dermatology. In particular, I am interested in the role of costimulatory and inhibitory immune receptors in cancer immunity, autoimmunity pathogenesis and immunotherapy. My interest in this field was driven by my experience in the Medical Scientist Training Program at Washington University in St. Louis, where I worked in the laboratory of Dr. Robert Schreiber to decipher key molecular regulators of cancer immunoediting. As a consequence, the expertise gained in skin immunology and the emerging immunotherapies to treat melanoma inspired me to become a dermatologist. During my dermatology residency, I joined the laboratory of Dr. Lieping Chen at Yale School of Medicine, who pioneered targeting the PD-1 axis for cancer immunotherapy and has discovered multiple novel immune checkpoint molecules including programmed death receptor-1 homolog (PD-1H) (also known as VISTA). My current research interests include: 1) identification of novel immune checkpoints such as PD-1H/VISTA and others in cutaneous malignancies (e.g., melanoma and keratinocyte carcinomas) and 2) elucidating the inhibitory immune landscape of chronic inflammatory disorders such as psoriasis and cutaneous lupus erythematosus.

Education & Training

  • Resident
    Yale School of Medicine (Dermatology) (2014-2017) (2017)
  • Intern
    Barnes Jewish Hospital (St. Louis) (2013-2014) (2014)
  • PhD
    Washington University School of Medicine, St. Louis, Immunology (2013)
  • MD
    Washington University School of Medicine (2013)
  • BS
    Creighton University, Biology, Theology, History (2003)

Honors & Recognition

AwardAwarding OrganizationDate
Dermatology Fellows AwardMelanoma Research Alliance2019
Physician-Scientist Career Development AwardDermatology Foundation2019
YCCI Research Scholar AwardYale Center for Clinical Investigation2019
Dermatologist Investigator Research FellowshipDermatology Foundation2017
Mentorship AwardMedical Dermatology Society2017

Professional Service

Lupus Research AllianceGrant Reviewer2022 - Present
International Dermatology Outcome Measures (IDEOM)Member2021 - Present
National Psoriasis FoundationMember2020 - Present
Rheumatological Dermatology SocietyMember2020 - Present
Society for Immunotherapy of Cancer (SITC)Member2020 - Present
American Academy of DermatologyFellow2018 - Present
Society of Investigative DermatologyBoard Member2018 - 2020
Society for Investigative DermatologyBoard Member2018 - 2020
New England Dermatological Society (NEDS)Member2017 - Present
Society for Investigative DermatologyMember2014 - Present
Medical Dermatology SocietyMember2014 - Present

Departments & Organizations