Margaret Altemus
Associate Professor of PsychiatryCards
About
Research
Publications
2024
The role of neurosteroids in posttraumatic stress disorder and alcohol use disorder: A review of 10 years of clinical literature and treatment implications
Peltier M, Verplaetse T, Altemus M, Zakiniaeiz Y, Ralevski E, Mineur Y, Gueorguieva R, Picciotto M, Cosgrove K, Petrakis I, McKee S. The role of neurosteroids in posttraumatic stress disorder and alcohol use disorder: A review of 10 years of clinical literature and treatment implications. Frontiers In Neuroendocrinology 2024, 73: 101119. PMID: 38184208, PMCID: PMC11185997, DOI: 10.1016/j.yfrne.2023.101119.Peer-Reviewed Original ResearchPosttraumatic stress disorderAlcohol use disorderStress disorderContext of PTSDPTSD/AUDConcurrent posttraumatic stress disorderUnderlying neurobiological mechanismsUse disordersAlcohol-related variablesNeurobiological mechanismsPTSD diagnosisTreatment developmentTreatment implicationsBody of literatureNovel interventionsClinical literatureRole of neurosteroidsDisordersTreatment outcomesYears of researchAlcohol consumptionExogenous pregnenolonePharmacological treatmentBiological variablesAllopregnanolone
2023
Does Symptom-Onset Treatment With Sertraline Improve Functional Impairment for Individuals With Premenstrual Dysphoric Disorder?
Yonkers K, Altemus M, Gilstad-Hayden K, Kornstein S, Gueorguieva R. Does Symptom-Onset Treatment With Sertraline Improve Functional Impairment for Individuals With Premenstrual Dysphoric Disorder? Journal Of Clinical Psychopharmacology 2023, 43: 320-325. PMID: 37212651, PMCID: PMC10313784, DOI: 10.1097/jcp.0000000000001700.Peer-Reviewed Original ResearchConceptsPremenstrual dysphoric disorderFunctional impairmentSymptom onsetPMDD symptomsDysphoric disorderAnger/irritabilityDaily treatmentActive treatmentFunctional outcomeClinical trialsFunctional improvementSecondary analysisCausal mediation analysisSertralineSeverity of problemsImpairmentNonsignificant direct effectDaily ratingsPlaceboTreatmentFace validitySymptomsIrritabilityDisordersSignificant indirect effect
2019
Chapter 55 Mental Health and Behavioral Disorders in Pregnancy ∗ ∗ Text for this chapter is available at ExpertConsult.com.
Wisner K, Sit D, Bogen D, Altemus M, Pearlstein T, Svikis D, Misra D, Miller E. Chapter 55 Mental Health and Behavioral Disorders in Pregnancy ∗ ∗ Text for this chapter is available at ExpertConsult.com. 2019, 409-410.e7. DOI: 10.1016/b978-0-323-60974-6.00055-4.Peer-Reviewed Original Research
2017
Chapter 55 Mental Health and Behavioral Disorders in Pregnancy
Wisner K, Sit D, Bogen D, Altemus M, Pearlstein T, Svikis D, Misra D, Miller E. Chapter 55 Mental Health and Behavioral Disorders in Pregnancy. 2017, 1147-1172.e5. DOI: 10.1016/b978-0-323-32108-2.00055-x.Peer-Reviewed Original Research
2015
Transcranial stimulation with low voltage, pulsed alternating current enhances parasympathetic activity
Altemus M, Mari S, Banerjee S, Yang R. Transcranial stimulation with low voltage, pulsed alternating current enhances parasympathetic activity. Brain Stimulation 2015, 8: 395. DOI: 10.1016/j.brs.2015.01.263.Peer-Reviewed Original Research
2014
Cranial Electrical Stimulation
Mindes J, Dubin M, Altemus M. Cranial Electrical Stimulation. 2014, 127-150. DOI: 10.1007/978-1-4939-1408-1_11.Peer-Reviewed Original ResearchCranial electrical stimulation (CES): Comparison with cranial nerve stimulation, transcranial direct current stimulation and transcranial low voltage pulsed electromagnetic fields
Mindes J, Dubin M, Altemus M. Cranial electrical stimulation (CES): Comparison with cranial nerve stimulation, transcranial direct current stimulation and transcranial low voltage pulsed electromagnetic fields. Brain Stimulation 2014, 7: e13. DOI: 10.1016/j.brs.2014.01.047.Peer-Reviewed Original ResearchCranial electrical stimulation (CES): Barriers to acceptance and new advances
Mindes J, Dubin M, Altemus M. Cranial electrical stimulation (CES): Barriers to acceptance and new advances. Brain Stimulation 2014, 7: e13. DOI: 10.1016/j.brs.2014.01.046.Peer-Reviewed Original ResearchThyroid Function And Depression In Pregnant Women In Qatar
Nasir M, Mari S, Abdulmalik M, Sheikh J, Altemus M. Thyroid Function And Depression In Pregnant Women In Qatar. 2014 DOI: 10.5339/qfarc.2014.hbpp0646.Peer-Reviewed Original Research
2013
A sensitive and selective LC-differential mobility-mass spectrometric analysis of allopregnanolone and pregnanolone in human plasma
Jin W, Jarvis M, Star-Weinstock M, Altemus M. A sensitive and selective LC-differential mobility-mass spectrometric analysis of allopregnanolone and pregnanolone in human plasma. Analytical And Bioanalytical Chemistry 2013, 405: 9497-9508. PMID: 24121434, PMCID: PMC3984615, DOI: 10.1007/s00216-013-7391-2.Peer-Reviewed Original ResearchMS/MS detectionSimple liquid-liquid extractionLinear calibration curveHexane/ethyl acetateHuman plasmaIntra-day precisionLiquid-liquid extractionIntra-day accuracyMobility separationQuality control samplesUnderivatized compoundsMS detectionSelective methodSpectrometric analysisConcentration rangeCalibration curveEthyl acetateLower limitSeparationColumnReagentsCompoundsEpimersPlasma samplesPg/mL