Lauren Gonzalez, PhD
Assistant Director of Scientific CommunicationAbout
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Titles
Assistant Director of Scientific Communication
Biography
Lauren received her dual B.A. in Biology & Literature from Claremont McKenna College, where she characterized novel proteins involved in plant stress responses, and her Ph.D. from Yale Genetics, where her research focused on the maternal contributions of small noncoding RNAs to germ cell development. She has also spent a collective 6 years teaching scientific communication, first as a Writing Consultant in the Center for Writing and Public Discourse at the Claremont Colleges and later as a Writing Fellow in Yale's Graduate Writing Lab. In 2021, she joined the Greco and Reinke labs in Yale Genetics as a Research Development fellow, focused on grant development and mentoring students and postdocs through manuscript writing.
Departments & Organizations
- All Institutions
Education & Training
- PhD
- Yale University, Genetics (2021)
- BA
- Claremont McKenna College, Biology & Literature (2014)
Research
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Research at a Glance
Yale Co-Authors
Publications Timeline
Haifan Lin, PhD
Susan Baserga, MD, PhD
Publications
2021
Maternal Piwi regulates primordial germ cell development to ensure the fertility of female progeny in Drosophila
Gonzalez LE, Tang X, Lin H. Maternal Piwi regulates primordial germ cell development to ensure the fertility of female progeny in Drosophila. Genetics 2021, 219: iyab091. PMID: 34142134, PMCID: PMC8757300, DOI: 10.1093/genetics/iyab091.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPIWI-interacting RNAsGermline developmentPiwi knockdownPIWI proteinsEarly embryosPiwi/piRNA complexesPIWI/piRNA pathwayFemale progenyPrimordial germ cell developmentGermline sex determinationLoss of PiwiGermline stem cellsDrosophila early embryosGerm cell developmentGerm cell proliferationGonad coalescencePiRNA complexesPiRNA pathwayPiRNA poolTransposon suppressionZygotic genesEmbryonic germlineEmbryonic functionEarly embryogenesisPiwi
2020
Piwi in the stem cell niche regulates nurse cell number and oocyte specification
Zhu G, Gonzalez LE, Lin H. Piwi in the stem cell niche regulates nurse cell number and oocyte specification. MicroPublication Biology 2020, 2020: 10.17912/micropub.biology.000327. PMID: 33274324, PMCID: PMC7704254, DOI: 10.17912/micropub.biology.000327.Peer-Reviewed Original ResearchOvarian somatic Piwi regulates nurse cell proliferation and oocyte specification in Drosophila
Gonzalez LE, Zhu G, Lin H. Ovarian somatic Piwi regulates nurse cell proliferation and oocyte specification in Drosophila. MicroPublication Biology 2020, 2020: 10.17912/micropub.biology.000324. PMID: 33274329, PMCID: PMC7704259, DOI: 10.17912/micropub.biology.000324.Peer-Reviewed Original ResearchCitationsAltmetricNop9 recognizes structured and single-stranded RNA elements of preribosomal RNA
Zhang J, Teramoto T, Qiu C, Wine RN, Gonzalez LE, Baserga SJ, Hall T. Nop9 recognizes structured and single-stranded RNA elements of preribosomal RNA. RNA 2020, 26: 1049-1059. PMID: 32371454, PMCID: PMC7373996, DOI: 10.1261/rna.075416.120.Peer-Reviewed Original ResearchCitations
2017
Transcriptome analysis uncovers Arabidopsis F-BOX STRESS INDUCED 1 as a regulator of jasmonic acid and abscisic acid stress gene expression.
Gonzalez LE, Keller K, Chan KX, Gessel MM, Thines BC. Transcriptome analysis uncovers Arabidopsis F-BOX STRESS INDUCED 1 as a regulator of jasmonic acid and abscisic acid stress gene expression. BMC Genomics 2017, 18: 533. PMID: 28716048, DOI: 10.1186/s12864-017-3864-6.Peer-Reviewed Original ResearchStructural analysis reveals the flexible C-terminus of Nop15 undergoes rearrangement to recognize a pre-ribosomal RNA folding intermediate.
Zhang J, Gonzalez LE, Hall TMT. Structural analysis reveals the flexible C-terminus of Nop15 undergoes rearrangement to recognize a pre-ribosomal RNA folding intermediate. Nucleic Acids Res 2017, 45: 2829-2837. PMID: 27789691, DOI: 10.1093/nar/gkw961.Peer-Reviewed Original Research
2016
Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA
Zhang J, McCann KL, Qiu C, Gonzalez LE, Baserga SJ, Hall TM. Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA. Nature Communications 2016, 7: 13085. PMID: 27725644, PMCID: PMC5062617, DOI: 10.1038/ncomms13085.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsEukaryotic ribosome biogenesisCorrect subcellular locationRibosome assembly factorsPre-ribosomal RNAPumilio repeatsRibosome biogenesisHuman ribosomopathiesAssembly factorsBiogenesis factorsRepeat proteinsMature rRNASubcellular locationNop9RNA complexCleavage siteRRNATimely cleavageProteinStructural featuresFinal processing stepRibosomopathiesBiogenesisCleavageYeastNuclease
Academic Achievements & Community Involvement
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