Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsKatrin Preller
Assistant Professor Adjunct, PsychiatryAbout
Research
Publications
2026
An international mega-analysis of psychedelic drug effects on brain circuit function
Girn M, Doss M, Roseman L, Preller K, Palhano-Fontes F, Pasquini L, Barrett F, Mallaroni P, Mason N, Timmermann C, McCulloch D, Fisher P, Winston B, Moujaes F, Muller F, Liechti M, Vollenweider F, Ramaekers J, Kuypers K, Araujo D, Sporns O, Siegel J, Dosenbach N, Nutt D, Carhart-Harris R, Stamatakis E, Bzdok D. An international mega-analysis of psychedelic drug effects on brain circuit function. Nature Medicine 2026, 32: 1543-1554. PMID: 41942645, PMCID: PMC13099416, DOI: 10.1038/s41591-026-04287-9.Peer-Reviewed Original ResearchConceptsResting-state functional magnetic resonance imaging studyPsychedelic effectsPsychedelic drugsFunctional connectivityMega-AnalysisWithin-network functional connectivityAcute psychedelic effectsPsychedelic drug effectsBrain circuit functionFunctional magnetic resonance imaging datasetsNeuroimaging researchWithin-networkSubcortical circuitryNeural mechanismsSubcortical regionsResting-state functional magnetic resonance imaging datasetsSensorimotor networkBrain functionBrain actionInconsistent findingsDrug effectsCortical organizationPsychedelicsCircuit functionWeak-to-moderateRelationship between rumination and symptoms of posttraumatic stress disorder – a cross-sectional network analysis
Zhabenko O, Ben-Zion Z, Raffelhüschen P, Burrer A, Seifritz E, Just S, Preller K, Duek O, Paterson M, Pietrzak R, Joormann J, Spiller T, Harpaz-Rotem I. Relationship between rumination and symptoms of posttraumatic stress disorder – a cross-sectional network analysis. Frontiers In Psychiatry 2026, 17: 1786768. DOI: 10.3389/fpsyt.2026.1786768.Peer-Reviewed Original ResearchSymptoms of posttraumatic stress disorderItem levelPosttraumatic Stress Disorder ChecklistAdult survivorsSurvivors of traumatic eventsCross-sectional network analysisMaintenance of PTSDGeneralized anxiety disorderRepetitive Thinking QuestionnairePosttraumatic stress disorderSymptoms of PTSDPatient Health QuestionnaireRisk-taking behaviorRTQ-10Hyperarousal clustersIntrusive memoriesAnxiety disordersPTSD symptomsRepetitive thoughtsPCL-5Stress disorderMood clusterCognitive processesGAD-7Thinking Questionnaire
2025
Dissecting Fear and Emotional Pain in PTSD: From Symptom Networks to Neural Signatures
Ben-Zion Z, Basol E, Simon A, Abargil M, Samonek K, Paterson M, Spiller T, Duek O, Just S, Preller K, Keynan J, Admon R, Liberzon I, Shalev A, Hendler T, Levy I, Joormann J, Scheinost D, Harpaz-Rotem I. Dissecting Fear and Emotional Pain in PTSD: From Symptom Networks to Neural Signatures. Biological Psychiatry 2025 PMID: 41319905, PMCID: PMC12784315, DOI: 10.1016/j.biopsych.2025.11.016.Peer-Reviewed Original ResearchPosttraumatic stress disorderConnectome-based predictive modelingEmotional painSymptom networksNeural signaturesSymptom severityStudy 1PTSD dimensionsPosttraumatic Stress Disorder ChecklistPosttraumatic stress disorder symptomsSubjective ratingsTrauma-exposed individualsTrauma-related psychopathologyDiverse symptom presentationsPost-traumaRatings of fearMechanism-based interventionsCentral executiveEmotional reactivityDSM-5PCL-5Distressing memoriesStress disorderDefault-modeCentral symptomsCorrection: Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging and phenomenology
Shinozuka K, Jerotic K, Mediano P, Zhao A, Preller K, Carhart-Harris R, Kringelbach M. Correction: Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging and phenomenology. Translational Psychiatry 2025, 15: 470. PMID: 41233360, PMCID: PMC12615698, DOI: 10.1038/s41398-025-03731-7.Commentaries, Editorials and LettersMemory deficits of MDMA users are linked to cortical thinning related to 5-HT receptor densities
Coray R, Beliveau V, Zimmermann J, Preller K, Wunderli M, Baumgartner M, Seifritz E, Stock A, Beste C, Cole D, Quednow B. Memory deficits of MDMA users are linked to cortical thinning related to 5-HT receptor densities. Brain 2025, 149: 1410-1421. PMID: 41123310, PMCID: PMC13058468, DOI: 10.1093/brain/awaf391.Peer-Reviewed Original ResearchGray matter volumeMDMA usersMatter volumeMemory deficitsMemory dysfunctionMDMA useVerbal long-term memoryRobust reductionReceptor densityReduction of gray matter volumeBrain gray matter structureVerbal memory dysfunctionStructural brain alterationsGray matter differencesVerbal memory performanceLong-term memoryShort-term recallLong-term recallMemory performance scoresGray matter structuresSerotonergic basisVerbal learningMemory performanceMnemonic functionsBrain alterationsVisual Hallucinations in Serotonergic Psychedelics and Lewy Body Diseases
Heller N, Barrett F, Buchborn T, Collerton D, Dupuis D, Halberstadt A, Jardri R, Noorani T, Preller K, Taylor J, Waters F, Winston B, Leptourgos P. Visual Hallucinations in Serotonergic Psychedelics and Lewy Body Diseases. Schizophrenia Bulletin 2025, 51: s273-s291. PMID: 41051875, PMCID: PMC12498954, DOI: 10.1093/schbul/sbaf068.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsVisual hallucinationsSerotonergic psychedelicsNeural mechanismsCortical activation patternsSerotonin 2ACore symptomsCognitive neuroscienceNeuroimaging studiesSerotonergic modulationAssociation cortexCortical signatureLewy body diseaseHallucinatory episodesCortical functionHallucinationsNeuromodulatory mechanismsSensory cortexReceptor upregulationSystems neuroscienceComplex hallucinationsActivity patternsPsychedelicsBody diseaseCortexNeuroscienceThe emotional architecture of the psychedelic brain
Moujaes F, Rieser N, Belinger L, Herdener M, Zahid Z, Preller K. The emotional architecture of the psychedelic brain. Trends In Cognitive Sciences 2025, 29: 1007-1022. PMID: 40830011, DOI: 10.1016/j.tics.2025.07.006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsEffects of psychedelicsImpact of psychedelicsEmotional processingMood disordersEmotional empathySerotonergic psychedelicsPsychiatric conditionsEmotion management strategiesPsychedelicsNeuroplastic changesMoodEmotional statesTemporal dynamicsEmotionsMechanism of actionComplex pictureTherapeutic impactEmotional architectureEmpathyDisordersBrainTherapeutic potentialClinical studiesTreatment approaches and efficacy in psychedelic-induced psychosis: A systematic review
Sulstarova A, Scheuerlein L, Monari S, Seragnoli F, Gabriel T, Preller K, Böge K, Sentissi O, Kaiser S, Solmi M, Kirschner M, Sabé M. Treatment approaches and efficacy in psychedelic-induced psychosis: A systematic review. Asian Journal Of Psychiatry 2025, 110: 104604. PMID: 40614615, DOI: 10.1016/j.ajp.2025.104604.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsFirst-generation antipsychoticsSecond-generation antipsychoticsElectroconvulsive therapySchizophrenia spectrum disordersRisk of psychosisSecond-generation agentsCase seriesCase reportFollow-upBipolar disorderAntipsychoticsMinority of usersPsychosisSpectrum disorderAverage patient agePrimary substanceFollow-up dataSystematic reviewInterpretation of findingsComprehensive follow-upTreatment approachesSecond-generationPatient ageProspective studyTreatment optionsA Consensus Taxonomy of Altered (Nonordinary) States of Consciousness: Bringing Order to Disarray
Cardeña E, Berkovich-Ohana A, Valli K, Barttfeld P, Gomez-Marin A, Greyson B, Kumar V, Laureys S, Luhrmann T, Newberg A, Preller K, Putnam F, Tagliazucchi E, Walsh R, Carter O, Yaden D. A Consensus Taxonomy of Altered (Nonordinary) States of Consciousness: Bringing Order to Disarray. Psychology Of Consciousness Theory Research And Practice 2025 DOI: 10.1037/cns0000431.Peer-Reviewed Original ResearchNeurocognitive effects of psilocybin: A systematic and comprehensive review of neuroimaging studies in humans
Berkovitch L, Fauvel B, Preller K, Gaillard R. Neurocognitive effects of psilocybin: A systematic and comprehensive review of neuroimaging studies in humans. Neuroscience & Biobehavioral Reviews 2025, 175: 106239. PMID: 40456393, DOI: 10.1016/j.neubiorev.2025.106239.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEffects of psilocybinPsilocybin effectsNeuroimaging studiesBrain changesNeuroimaging techniquesTherapeutic effects of psilocybinTreat various psychiatric disordersFunctional brain changesSamples of healthy volunteersSerotonergic compoundsEmotional processingNeurobiological mechanismsMode networkPsychiatric disordersCognitive tasksPsychoactive effectsBrain activityNeuroimaging dataPsilocybinSelf-experienceAssociated with acute alterationsSocial functioningTherapeutic effectBrainNeuronal networks