Ilan Harpaz-Rotem, PhD, ABPP
Glenn H. Greenberg Professor of Psychiatry and of PsychologyDownloadHi-Res Photo
Cards
Appointments
Psychiatry
Primary
Department of Psychology
Secondary
Additional Titles
Director, PTSD Advanced Fellowship in Mental Illness Research and Treatment
Deputy Director, Evaluation Division at the National Center for PTSD, VA Connecticut Healthcare System
Contact Info
Appointments
Psychiatry
Primary
Department of Psychology
Secondary
Additional Titles
Director, PTSD Advanced Fellowship in Mental Illness Research and Treatment
Deputy Director, Evaluation Division at the National Center for PTSD, VA Connecticut Healthcare System
Contact Info
Appointments
Psychiatry
Primary
Department of Psychology
Secondary
Additional Titles
Director, PTSD Advanced Fellowship in Mental Illness Research and Treatment
Deputy Director, Evaluation Division at the National Center for PTSD, VA Connecticut Healthcare System
Contact Info
About
Copy Link
Titles
Glenn H. Greenberg Professor of Psychiatry and of Psychology
Director, PTSD Advanced Fellowship in Mental Illness Research and Treatment
Positions outside Yale
Deputy Director, Evaluation Division at the National Center for PTSD, VA Connecticut Healthcare System
Biography
Dr. Harpaz-Rotem is a Professor of Psychiatry and of Psychology at Yale University. He is a clinical psychologist who, for many years, has conducted research and provided treatment to individuals exposed to trauma. Dr. Harpaz-Rotem serves as an investigator at the National Center for PTSD, and he also directs the evaluation of VA PTSD treatment programs at the Department of Veterans Affairs, Northeast Program Evaluation Center, Office of Mental Health and Suicide Prevention, VA Central Office. Research into how to modify traumatic memories and their associated emotions is one of the core questions that guide his work.
Last Updated on December 15, 2022.
Appointments
Psychiatry
ProfessorPrimaryDepartment of Psychology
ProfessorSecondary
Other Departments & Organizations
- Center for Brain & Mind Health
- Department of Psychology
- Harpaz-Rotem Lab
- MR Core
- Psychiatry
- Psychology Section
- VA National Center for PTSD
- VA-Yale Clinical Neurosciences PTSD Research Program
- Wu Tsai Institute
- Yale Ventures
Education & Training
- PhD
- New School for Social Research (2002)
- Clinical training
- Albert Einstein School of Medicine Bronx Lebanon Hospital (2001)
Research
Copy Link
Overview
Medical Research Interests
Afghanistan; Anxiety Disorders; Biomarkers, Pharmacological; Depression; Iraq; Magnetic Resonance Imaging; Mental Health Services; Positron Emission Tomography Computed Tomography; Psychiatry; Psychotherapy; Stress Disorders, Post-Traumatic; Veterans
ORCID
0000-0002-6066-9406- View Lab Website
Harpaz-Rotem PTSD Treatment & Research Lab
Research at a Glance
Yale Co-Authors
Frequent collaborators of Ilan Harpaz-Rotem's published research.
Publications Timeline
A big-picture view of Ilan Harpaz-Rotem's research output by year.
Research Interests
Research topics Ilan Harpaz-Rotem is interested in exploring.
Jack Tsai
Or Duek, PhD
John Krystal, MD
Robert Pietrzak, PhD, MPH
Tobias Spiller, MD
Ifat Levy, PhD
202Publications
6,223Citations
Stress Disorders, Post-Traumatic
Veterans
Magnetic Resonance Imaging
Psychotherapy
Mental Health Services
Depression
Publications
2026
A Continuum Is Not a Hammer: Response to Lowell and Markowitz (2026) on the Exposure Continuum Model
Rubinstein D, Korem N, Bullard D, Harpaz-Rotem I. A Continuum Is Not a Hammer: Response to Lowell and Markowitz (2026) on the Exposure Continuum Model. Journal Of Anxiety Disorders 2026, 103200. PMID: 42297653, DOI: 10.1016/j.janxdis.2026.103200.Peer-Reviewed Original ResearchBeyond Drinking: Psychosocial Complexity and Dropout From Department of Veterans Affairs Posttraumatic Stress Disorder (PTSD) Residential Treatment
Ingram P, Gross G, Harpaz-Rotem I, Meshberg-Cohen S. Beyond Drinking: Psychosocial Complexity and Dropout From Department of Veterans Affairs Posttraumatic Stress Disorder (PTSD) Residential Treatment. Psychological Services 2026 PMID: 42207653, DOI: 10.1037/ser0001045.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderAlcohol use disorderPsychiatric symptom severityResidential rehabilitation treatment programsSymptom severityRehabilitation treatment programStress disorderDrinking daysUse disorderSubstance useTreatment programsPosttraumatic stress disorder treatmentAlcohol use disorder diagnosisPredictors of treatment completionBinge drinking daysSubstance use disordersIllicit substance useResidential treatmentTreatment dropoutDrinking behaviorU.S. veteransAlcohol useTreatment completionComplex comorbiditiesNoncompletionNational Trends in Posttraumatic Stress Disorder Among US Military Veterans: Results From the 2025-2026 National Health and Resilience in Veterans Study.
Pietrzak R, Fischer I, Na P, Harpaz-Rotem I, Petrakis I, Krystal J. National Trends in Posttraumatic Stress Disorder Among US Military Veterans: Results From the 2025-2026 National Health and Resilience in Veterans Study. The Journal Of Clinical Psychiatry 2026, 87 PMID: 42207989, DOI: 10.4088/jcp.26m16378.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsNational Health and ResilienceWeighted prevalence estimatesMethods: DataUS military veteransFunctional disabilityTrauma burdenPosttraumatic stress disorderWeighted prevalenceVeterans StudyUS veteransAssociated with functional disabilityMilitary veteransPast-month prevalenceResults:Racial/ethnic minority veteransLife-threatening illnessPrevalence of posttraumatic stress disorderWeb-based surveyStress disorderTrauma exposureNational surveillance dataLifetime trauma exposureMinority veteransClinical careVeteran populationReconciling hippocampal semantic representations of traumatic memory in PTSD
Schiller D, Perl O, Duek O, levy I, Harpaz-Rotem I. Reconciling hippocampal semantic representations of traumatic memory in PTSD. Neuropsychopharmacology 2026, 51: 1524-1525. PMID: 42174026, PMCID: PMC13291350, DOI: 10.1038/s41386-026-02451-w.Peer-Reviewed Original ResearchAltmetricImproving PTSD Treatment With Ketamine-Augmented Exposure Therapy: A Double-Blind Randomized Clinical Trial
Harpaz-Rotem I, Abargail M, Duek O, Korem N, Rubinstein D, Keynan N, Harari A, Eizenbach T, Kang M, Koryto Y, Sharon H, Nia A, Krystal J, Hendler T. Improving PTSD Treatment With Ketamine-Augmented Exposure Therapy: A Double-Blind Randomized Clinical Trial. Biological Psychiatry 2026, 99: s45. DOI: 10.1016/j.biopsych.2026.03.114.Peer-Reviewed Original Research612. Childhood Maltreatment is Associated With Blunted Hippocampal Offline Reinstatement After Idiosyncratic Trauma Recall in PTSD
Qu Y, Basol E, Paterson M, Davydovska T, Samonek K, Ben-Zion Z, Korem N, Cocuzza C, Joormann J, Harpaz-Rotem I. 612. Childhood Maltreatment is Associated With Blunted Hippocampal Offline Reinstatement After Idiosyncratic Trauma Recall in PTSD. Biological Psychiatry 2026, 99: s361-s362. DOI: 10.1016/j.biopsych.2026.03.846.Peer-Reviewed Original Research604. A Naturalistic fMRI Encoding Framework for Autobiographical Trauma Recall in PTSD: A Proof-Of-Concept Study
Duek O, Sulem E, Gordon C, Harpaz-Rotem I. 604. A Naturalistic fMRI Encoding Framework for Autobiographical Trauma Recall in PTSD: A Proof-Of-Concept Study. Biological Psychiatry 2026, 99: s358. DOI: 10.1016/j.biopsych.2026.03.838.Peer-Reviewed Original Research603. Facial Emotion Dynamics During Prolonged Exposure Therapy in a Ketamine-Enhanced PTSD Trial
Davydovska T, Abargil M, Harpaz-Rotem I. 603. Facial Emotion Dynamics During Prolonged Exposure Therapy in a Ketamine-Enhanced PTSD Trial. Biological Psychiatry 2026, 99: s358. DOI: 10.1016/j.biopsych.2026.03.837.Peer-Reviewed Original Research233. Knowledge-Informed Natural Language Processing for PTSD Identification From Free Recall Transcriptions
Sulem E, Duek O, Goldshtein E, Magrisso N, Harpaz-Rotem I. 233. Knowledge-Informed Natural Language Processing for PTSD Identification From Free Recall Transcriptions. Biological Psychiatry 2026, 99: s198. DOI: 10.1016/j.biopsych.2026.03.467.Peer-Reviewed Original Research241. Neural Circuitry of “Hotspots” During Free Trauma Recollection in PTSD
Rubinstein D, Korem N, Duek O, Abargail M, Basol E, Davydovska T, Gordon C, O'Brien E, Metviner S, Harpaz-Rotem I, Basol E. 241. Neural Circuitry of “Hotspots” During Free Trauma Recollection in PTSD. Biological Psychiatry 2026, 99: s202. DOI: 10.1016/j.biopsych.2026.03.475.Peer-Reviewed Original Research
Clinical Trials
Current Trials
Eligibility for Participation in Neuroimaging Studies
IRB ID2000027842RoleSub InvestigatorPrimary Completion Date12/31/2023Recruiting ParticipantsUsing Neuroimaging to track symptom change in PTSD treatment
IRB ID2000025892RolePrincipal InvestigatorPrimary Completion Date07/31/2029Recruiting ParticipantsImaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
IRB ID1005006735RoleSub InvestigatorPrimary Completion Date12/31/2016Recruiting ParticipantsGenderMaleAge18 years - 55 yearsImaging mGluR5 and synaptic density in psychiatric disorders
IRB ID2000020186RoleSub InvestigatorPrimary Completion Date01/31/2018Recruiting ParticipantsGenderBothAge18 years - 80 yearsIntensive 7-day Treatment for PTSD Combining Ketamine With Exposure Therapy (PTSD)
IRB ID1509016530RolePrincipal InvestigatorPrimary Completion Date08/01/2030Recruiting ParticipantsGenderBothAge21 years - 70 years
Academic Achievements & Community Involvement
Copy Link
Honors
honor Distinguished Mentorship Award
11/11/2022National AwardInternational Society for Traumatic Stress Studies (ISTSS)DetailsUnited States
News & Links
Copy Link
News
- May 26, 2026Source: The Journal of Clinical Psychiatry
National Trends in Posttraumatic Stress Disorder Among US Military Veterans: Results From the 2025–2026 National Health and Resilience in Veterans Study
- January 13, 2026
More Than Just Fear: A New Profile of Post-traumatic Stress Disorder
- October 20, 2025
Understanding PTSD and Dissociation in Wartime: Direct and Indirect Trauma Exposure
- September 18, 2025
Yale Scientists Seek to Uncover Neural and Genomic Mechanisms that Drive Anxiety
Get In Touch
Copy Link
Contacts
Academic Office Number
Mailing Address
Psychiatry
300 George Street
New Haven, CT 06511
United States
Locations
300 George Street
Academic Office
Rm 836
New Haven, CT 06511