Edward J Miller, MD, PhD

2026

• Hidden risk in normal myocardial perfusion scans: AI-detected proximal coronary calcium on CT attenuation maps improves prognosis

  Zhou J, Miller R, Shanbhag A, Killekar A, Han D, Patel K, Pieszko K, Yi J, Urs M, Ramirez G, Lemley M, Kavanagh P, Liang J, Kamagate A, Builoff V, Einstein A, Feher A, Miller E, Sinusas A, Ruddy T, Knight S, Le V, Mason S, Chareonthaitawee P, Wopperer S, Alexanderson E, Carvajal-Juarez I, Rosamond T, Slipczuk L, Travin M, Packard R, Acampa W, Al-Mallah M, deKemp R, Buechel R, Berman D, Dey D, Di Carli M, Slomka P. Hidden risk in normal myocardial perfusion scans: AI-detected proximal coronary calcium on CT attenuation maps improves prognosis. European Journal Of Nuclear Medicine And Molecular Imaging 2026, 1-11. PMID: 42517890, PMCID: PMC13492496, DOI: 10.1007/s00259-026-08084-x.

  Peer-Reviewed Original Research

• Diagnostic Performance of the Mayo ATTR-CM Score in Diverse Populations Comparison With the AMY Score

  Carey P, Barrera N, Tersalvi G, Ansari B, Alreshq R, Davies D, Dispenzieri A, Fine D, de Freitas C, Gallegos-Kattan C, Garmany A, Grogan M, Helmke S, Miller E, Pellikka P, Scott C, Teruya S, Ullah I, Ruberg F, Maurer M, AbouEzzeddine O. Diagnostic Performance of the Mayo ATTR-CM Score in Diverse Populations Comparison With the AMY Score. JACC Advances 2026, 5: 102843. PMID: 42312781, PMCID: PMC13308236, DOI: 10.1016/j.jacadv.2026.102843.

  Peer-Reviewed Original Research

• Blunted heart rate response to regadenoson predicts cardiovascular risk beyond quantitative positron emission tomography myocardial blood flow

  Barreto J, Vashist A, Gallegos Kattan C, Stendahl J, Sadeghi M, Sposito A, Miller E, Sinusas A, Feher A, Moura F. Blunted heart rate response to regadenoson predicts cardiovascular risk beyond quantitative positron emission tomography myocardial blood flow. Journal Of Nuclear Cardiology 2026, 61: 102766. PMID: 42190937, DOI: 10.1016/j.nuclcard.2026.102766.

  Peer-Reviewed Original Research

  Citations

• Quantitative cardiac amyloid radionuclide imaging

  Miller R, Clerc O, Cuddy S, Auer B, Kijewski M, Miller E, Slomka P, Dorbala S. Quantitative cardiac amyloid radionuclide imaging. Journal Of Nuclear Cardiology 2026, 59: 102724. PMID: 42142945, DOI: 10.1016/j.nuclcard.2026.102724.

  Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements

  MeSH Keywords

• Importance of Understanding the Kinetics of Cardiac Amyloid Radionuclide Imaging

  Miller E, Gallegos C, Sinusas A. Importance of Understanding the Kinetics of Cardiac Amyloid Radionuclide Imaging. Circulation Cardiovascular Imaging 2026, 19: e019837. PMID: 42059083, DOI: 10.1161/circimaging.126.019837.

  Commentaries, Editorials and Letters

• Fully Automated vs. Human Echocardiogram Interpretation in Transthyretin Amyloid Cardiomyopathy: The SCAN-MP Study

  McMenamin K, Teruya S, Slivnick J, Alreshq R, Ullah I, Fine D, Elzieny A, Helmke S, Gallegos C, Miller E, Asch F, Hasan S, Maurer M, Ruberg F. Fully Automated vs. Human Echocardiogram Interpretation in Transthyretin Amyloid Cardiomyopathy: The SCAN-MP Study. Journal Of The American Society Of Echocardiography 2026, s0894-7317(26)00176-8. PMID: 42066965, PMCID: PMC13182997, DOI: 10.1016/j.echo.2026.04.012.

  Peer-Reviewed Original Research

• Assessing Coronary Calcium Thresholds on Attenuation-Correction CT With Myocardial Perfusion Imaging Equating to Secondary Prevention

  Kyriakoulis I, Csecs I, Ahmed A, Wright C, Shanbhag A, Lemley M, Slomka P, Sinusas A, Miller E, Kokkinidis D, Feher A. Assessing Coronary Calcium Thresholds on Attenuation-Correction CT With Myocardial Perfusion Imaging Equating to Secondary Prevention. JACC Advances 2026, 5: 102732. PMID: 42000549, PMCID: PMC13098618, DOI: 10.1016/j.jacadv.2026.102732.

  Peer-Reviewed Original Research

• Association of rheumatoid arthritis with major adverse cardiovascular events despite normal myocardial perfusion imaging

  Frohlich B, Pires J, Kyrakoulis I, Wright C, Csecs I, Ahmed A, Jones X, Jacobs M, Hinchcliff M, Miller E, Feher A. Association of rheumatoid arthritis with major adverse cardiovascular events despite normal myocardial perfusion imaging. American Journal Of Preventive Cardiology 2026, 29: 101624. PMID: 42403439, PMCID: PMC13329586, DOI: 10.1016/j.ajpc.2026.101624.

  Peer-Reviewed Original Research

  Altmetric

• Coronary calcifications and myocardial flow reserve in heart transplant patients: a longitudinal study

  Wright C, Kiage J, Kyriakoulis I, Csecs I, Ahmed A, Tong G, Zeng Y, Liu Y, Bellumkonda L, Kokkinidis D, Sinusas A, Miller E, Feher A. Coronary calcifications and myocardial flow reserve in heart transplant patients: a longitudinal study. European Heart Journal 2026, 47: 3214-3216. PMID: 41780909, DOI: 10.1093/eurheartj/ehag163.

  Peer-Reviewed Original Research

  Citations

• Parametric Cardiac Imaging with 18F-Flutemetamol PET to Evaluate the Impact of Tafamidis in Patients with Transthyretin Cardiac Amyloidosis.

  Liu Q, Shi T, Sharma A, De Freitas C, Fazzone-Chettiar R, Van Laere K, Baldick A, Kattan C, Guo X, Guo L, Xie H, Chen X, Zhou B, Liu Y, Carson R, Liu C, Miller E. Parametric Cardiac Imaging with 18F-Flutemetamol PET to Evaluate the Impact of Tafamidis in Patients with Transthyretin Cardiac Amyloidosis. Journal Of Nuclear Medicine 2026, 67: 780-787. PMID: 41748295, DOI: 10.2967/jnumed.125.270003.

  Peer-Reviewed Original Research

  This study investigates dynamic 18F-flutemetamol PET imaging for measuring amyloid burden in transthyretin cardiac amyloidosis, showing significant reductions after 6 months of tafamidis treatment.

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