Brian Feldman, MD, PhD
C.N.H. Long Professor of Pediatrics (Endocrinology)Cards
About
Research
Publications
2025
Characterization and lineage tracing of a mouse adipose depot reveal properties conserved with human supraclavicular brown adipose tissue
Li L, Feldman B. Characterization and lineage tracing of a mouse adipose depot reveal properties conserved with human supraclavicular brown adipose tissue. Stem Cell Reports 2025, 20: 102509. PMID: 40409261, PMCID: PMC12181967, DOI: 10.1016/j.stemcr.2025.102509.Peer-Reviewed Original Research
2024
White adipocytes in subcutaneous fat depots require KLF15 for maintenance in preclinical models
Li L, Feldman B. White adipocytes in subcutaneous fat depots require KLF15 for maintenance in preclinical models. Journal Of Clinical Investigation 2024, 134: e172360. PMID: 38949025, PMCID: PMC11213504, DOI: 10.1172/jci172360.Peer-Reviewed Original ResearchRepurposing mebendazole against triple-negative breast cancer CNS metastasis
Rodrigues A, Chernikova S, Wang Y, Trinh T, Solow-Cordero D, Alexandrova L, Casey K, Alli E, Aggarwal A, Quill T, Koegel A, Feldman B, Ford J, Hayden-Gephart M. Repurposing mebendazole against triple-negative breast cancer CNS metastasis. Journal Of Neuro-Oncology 2024, 168: 125-138. PMID: 38563850, PMCID: PMC11093727, DOI: 10.1007/s11060-024-04654-x.Peer-Reviewed Original Research
2023
Glucocorticoid signaling and the impact of high-fat diet on adipogenesis in vivo
Babel N, Feldman B. Glucocorticoid signaling and the impact of high-fat diet on adipogenesis in vivo. Steroids 2023, 201: 109336. PMID: 37944652, PMCID: PMC11005958, DOI: 10.1016/j.steroids.2023.109336.Peer-Reviewed Original ResearchQuantification of cell energetics in human subcutaneous adipose progenitor cells after target gene knockdown
Li L, Gunewardena A, Nyima T, Feldman B. Quantification of cell energetics in human subcutaneous adipose progenitor cells after target gene knockdown. STAR Protocols 2023, 4: 102607. PMID: 37742183, PMCID: PMC10751552, DOI: 10.1016/j.xpro.2023.102607.Peer-Reviewed Original ResearchIdentification of an adipose tissue-resident pro-preadipocyte population
Chen M, Kim S, Li L, Chattopadhyay S, Rando T, Feldman B. Identification of an adipose tissue-resident pro-preadipocyte population. Cell Reports 2023, 42: 112440. PMID: 37119138, PMCID: PMC10370484, DOI: 10.1016/j.celrep.2023.112440.Peer-Reviewed Original Research
2021
MYH9 facilitates autoregulation of adipose tissue depot development
Cheung S, Sayeed M, Nakuluri K, Li L, Feldman B. MYH9 facilitates autoregulation of adipose tissue depot development. JCI Insight 2021, 6: e136233. PMID: 33986190, PMCID: PMC8262332, DOI: 10.1172/jci.insight.136233.Peer-Reviewed Original Research14 The Adrenal Cortex and Its Disorders
Miller W, Flück C, Breault D, Feldman B. 14 The Adrenal Cortex and Its Disorders. 2021, 425-490. DOI: 10.1016/b978-0-323-62520-3.00014-2.Chapters
2020
A Novel Radioligand Reveals Tissue Specific Pharmacological Modulation of Glucocorticoid Receptor Expression with Positron Emission Tomography
Huang Y, Zhao N, Wang Y, Truillet C, Wei J, Blecha J, VanBrocklin H, Seo Y, Sayeed M, Feldman B, Aggarwal R, Behr S, Shao H, Wilson D, Villanueva-Meyer J, Gestwicki J, Evans M. A Novel Radioligand Reveals Tissue Specific Pharmacological Modulation of Glucocorticoid Receptor Expression with Positron Emission Tomography. ACS Chemical Biology 2020, 15: 1381-1391. PMID: 32255605, PMCID: PMC8031368, DOI: 10.1021/acschembio.9b01043.Peer-Reviewed Original Research
2019
A novel platform for isotype-specific testing of autoantibodies
Carter K, Treurnicht A, Davis K, Kumar R, Feldman B. A novel platform for isotype-specific testing of autoantibodies. PLOS ONE 2019, 14: e0211596. PMID: 30730939, PMCID: PMC6366878, DOI: 10.1371/journal.pone.0211596.Peer-Reviewed Original Research
Clinical Care
Overview
Brian Feldman, MD, PhD, is a pediatric endocrinologist who specializes in treating hormonal disorders in children, including diabetes and conditions affecting growth and metabolism. He employs a comprehensive approach to care, using his expertise to improve the lives of young patients with complex endocrine challenges.
As the C.N.H. Long Professor of Pediatrics (endocrinology) at Yale School of Medicine, Dr. Feldman conducts research on the role of steroid hormones in determining cell fate, with particular interest in obesity, type 2 diabetes, and the development of brown fat. His work aims to uncover new treatment pathways for metabolic conditions and has garnered significant recognition, including prestigious awards such as the Clinical Scholars Award from the Pediatric Endocrine Society and the NIH Director’s New Innovator Award.
Dr. Feldman received his medical and doctoral degrees from Stanford University. He completed his residency in pediatrics at Harvard University-affiliated Boston Children’s Hospital and pursued a fellowship in pediatric endocrinology at the University of California, San Francisco.
News
News
Get In Touch
Contacts
Locations
Patient Care Locations
Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.