Benjamin Landis, MD
Associate Professor TermCards
About
Research
Publications
2026
Rapid Genome Sequencing Shows Diagnostic Utility in Infants With Congenital Heart Defects
Durbin M, Helvaty L, Posorske A, Zhang S, Huang M, Li M, Abreu D, Fairman K, Geddes G, Helm B, Landis B, McEntire A, Mitchell D, Ware S. Rapid Genome Sequencing Shows Diagnostic Utility in Infants With Congenital Heart Defects. Circulation Genomic And Precision Medicine 2026, 19: e005367. PMID: 41958385, DOI: 10.1161/circgen.125.005367.Peer-Reviewed Original Research
2025
Combined genome and transcriptome analysis identifies molecular signatures of aortic disease in patients with Marfan syndrome
Stanley K, Mederos A, Barksdale E, Corvera J, Davis J, Fang F, Gao H, Vujakovich C, Liu Y, Ware S, Landis B. Combined genome and transcriptome analysis identifies molecular signatures of aortic disease in patients with Marfan syndrome. Journal Of Molecular And Cellular Cardiology Plus 2025, 13: 100467. PMID: 40678173, PMCID: PMC12269431, DOI: 10.1016/j.jmccpl.2025.100467.Peer-Reviewed Original ResearchDysmorphology-Based Prediction Model for Genetic Disorders in Infants With Congenital Heart Disease
Helm B, Wetherill L, Landis B, Ware S. Dysmorphology-Based Prediction Model for Genetic Disorders in Infants With Congenital Heart Disease. Circulation Genomic And Precision Medicine 2025, 18: e004895. PMID: 40151936, PMCID: PMC11999770, DOI: 10.1161/circgen.124.004895.Peer-Reviewed Original ResearchIdentification of Long Noncoding RNA Candidate Disease Genes Associated With Clinically Reported Copy Number Variants in Congenital Heart Disease
Penaloza J, Moreland B, Gaither J, Landis B, Ware S, McBride K, White P, Helvaty L, Geddes G, Hodge J, Garg V, Lo C, Yatsenko S, Lin J, Wechsler S, Lalani S. Identification of Long Noncoding RNA Candidate Disease Genes Associated With Clinically Reported Copy Number Variants in Congenital Heart Disease. Journal Of The American Heart Association 2025, 14: e039177. PMID: 40079339, PMCID: PMC12132622, DOI: 10.1161/jaha.124.039177.Peer-Reviewed Original Research
2024
Performance of Dysmorphology‐Based Screening for Genetic Disorders in Pediatric Congenital Heart Disease Supports Wider Genetic Testing
Helm B, Helvaty L, Conboy E, Geddes G, Graham B, Lah M, Wetherill L, Landis B, Ware S. Performance of Dysmorphology‐Based Screening for Genetic Disorders in Pediatric Congenital Heart Disease Supports Wider Genetic Testing. Molecular Genetics & Genomic Medicine 2024, 12: e70040. PMID: 39587733, PMCID: PMC11588853, DOI: 10.1002/mgg3.70040.Peer-Reviewed Original ResearchA Novel Echocardiography Feature-Tracking Algorithm for Stabilized Frame-to-Frame Extraction of Aortic Root Diameters in the Parasternal Long Axis
Damen F, Ghajar-Rahimi E, Lai D, Goergen C, Landis B. A Novel Echocardiography Feature-Tracking Algorithm for Stabilized Frame-to-Frame Extraction of Aortic Root Diameters in the Parasternal Long Axis. Journal Of The American Society Of Echocardiography 2024, 38: 44-47. PMID: 39299353, PMCID: PMC11700755, DOI: 10.1016/j.echo.2024.09.005.Peer-Reviewed Original ResearchEarly ascertainment of genetic diagnoses clarifies impact on medium-term survival following neonatal congenital heart surgery
Landis B, Helm B, Durbin M, Helvaty L, Herrmann J, Johansen M, Geddes G, Ware S. Early ascertainment of genetic diagnoses clarifies impact on medium-term survival following neonatal congenital heart surgery. Journal Of Clinical Investigation 2024, 134: e180098. PMID: 39078715, PMCID: PMC11405028, DOI: 10.1172/jci180098.Peer-Reviewed Original ResearchSilencing COQ8B in Aortic Smooth Muscle Cells Reveals Cellular Dysfunction Related to Changes in Cell Proliferation
Davis J, Landis B. Silencing COQ8B in Aortic Smooth Muscle Cells Reveals Cellular Dysfunction Related to Changes in Cell Proliferation. Proceedings Of IMPRS 2024, 6 DOI: 10.18060/27779.Peer-Reviewed Original Research
2023
A Multicenter Analysis of Abnormal Chromosomal Microarray Findings in Congenital Heart Disease
Landis B, Helvaty L, Geddes G, Lin J, Yatsenko S, Lo C, Border W, Wechsler S, Murali C, Azamian M, Lalani S, Hinton R, Garg V, McBride K, Hodge J, Ware S. A Multicenter Analysis of Abnormal Chromosomal Microarray Findings in Congenital Heart Disease. Journal Of The American Heart Association 2023, 12: e029340. PMID: 37681527, PMCID: PMC10547279, DOI: 10.1161/jaha.123.029340.Peer-Reviewed Original ResearchClinical exome sequencing efficacy and phenotypic expansions involving anomalous pulmonary venous return
Huth E, Zhao X, Owen N, Luna P, Vogel I, Dorf I, Joss S, Clayton-Smith J, Parker M, Louw J, Gewillig M, Breckpot J, Kraus A, Sasaki E, Kini U, Burgess T, Tan T, Armstrong R, Neas K, Ferrero G, Brusco A, Kerstjens-Frederikse W, Rankin J, Helvaty L, Landis B, Geddes G, McBride K, Ware S, Shaw C, Lalani S, Rosenfeld J, Scott D. Clinical exome sequencing efficacy and phenotypic expansions involving anomalous pulmonary venous return. European Journal Of Human Genetics 2023, 31: 1430-1439. PMID: 37673932, PMCID: PMC10689790, DOI: 10.1038/s41431-023-01451-4.Peer-Reviewed Original Research