Bao Wang
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About
Appointments
Departments & Organizations
Education & Training
- BS
- Nanjing University, Biological Sciences (2018)
Research
Overview
Medical Subject Headings (MeSH)
Epithelial Cells; Immunity, Innate; Rhinovirus
ORCID
0000-0002-6472-2307- View Lab Website
Foxman Lab
Research at a Glance
Yale Co-Authors
Frequent collaborators of Bao Wang's published research.
Research Interests
Research topics Bao Wang is interested in exploring.
Ellen F Foxman, MD, PhD
David van Dijk, PhD, MSc, BSc
Guilin Wang, PhD
Akiko Iwasaki, PhD
Allison M. Greaney, PhD
Anna Marie Pyle, PhD
Immunity, Innate
Publications
2023
Causal identification of single-cell experimental perturbation effects with CINEMA-OT
Dong M, Wang B, Wei J, de O. Fonseca A, Perry C, Frey A, Ouerghi F, Foxman E, Ishizuka J, Dhodapkar R, van Dijk D. Causal identification of single-cell experimental perturbation effects with CINEMA-OT. Nature Methods 2023, 20: 1769-1779. PMID: 37919419, PMCID: PMC10630139, DOI: 10.1038/s41592-023-02040-5.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and Concepts
2021
Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics
Cheemarla NR, Watkins TA, Mihaylova VT, Wang B, Zhao D, Wang G, Landry ML, Foxman EF. Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics. Journal Of Experimental Medicine 2021, 218: e20210583. PMID: 34128960, PMCID: PMC8210587, DOI: 10.1084/jem.20210583.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAdultAgedAged, 80 and overAngiotensin-Converting Enzyme 2Case-Control StudiesChemokine CXCL10COVID-19Disease SusceptibilityFemaleGene Expression ProfilingHost-Pathogen InteractionsHumansImmunity, InnateInterferonsMaleMiddle AgedNasopharynxPicornaviridae InfectionsSARS-CoV-2Viral LoadVirus ReplicationConceptsSARS-CoV-2 infectionSARS-CoV-2 exposureSARS-CoV-2Interferon-stimulated genesUpper respiratory tractRespiratory tractEarly SARS-CoV-2 infectionDynamic innate immune responseViral replicationSARS-CoV-2 replicationPatient nasopharyngeal samplesInnate immune responseLow infectious doseViral loadNasopharyngeal samplesImmune responseInfectious doseISG responseAntiviral responseInfection progressionViral transmissionLevel correlatesInfectionISG inductionInitial replicationSingle-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes
Ravindra NG, Alfajaro MM, Gasque V, Huston NC, Wan H, Szigeti-Buck K, Yasumoto Y, Greaney AM, Habet V, Chow RD, Chen JS, Wei J, Filler RB, Wang B, Wang G, Niklason LE, Montgomery RR, Eisenbarth SC, Chen S, Williams A, Iwasaki A, Horvath TL, Foxman EF, Pierce RW, Pyle AM, van Dijk D, Wilen CB. Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes. PLOS Biology 2021, 19: e3001143. PMID: 33730024, PMCID: PMC8007021, DOI: 10.1371/journal.pbio.3001143.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSARS-CoV-2 infectionSARS-CoV-2Human bronchial epithelial cellsInterferon-stimulated genesCell state changesAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSyndrome coronavirus 2 infectionCell tropismCoronavirus 2 infectionCoronavirus disease 2019Onset of infectionCell-intrinsic expressionCourse of infectionAir-liquid interface culturesHost-viral interactionsBronchial epithelial cellsSingle-cell RNA sequencingCell typesIL-1Disease 2019Human airwaysDevelopment of therapeuticsDrug AdministrationViral replication
2018
A surface-display biohybrid approach to light-driven hydrogen production in air
Wei W, Sun P, Li Z, Song K, Su W, Wang B, Liu Y, Zhao J. A surface-display biohybrid approach to light-driven hydrogen production in air. Science Advances 2018, 4: eaap9253. PMID: 29492458, PMCID: PMC5821488, DOI: 10.1126/sciadv.aap9253.Peer-Reviewed Original ResearchCitationsAltmetricConceptsSolar-to-chemical productionHydrogen productionLight-driven hydrogen productionPhotocatalytic hydrogen productionLight-harvesting semiconductorsCadmium sulfide nanoparticlesCatalytic approachSurface-display systemInduce hydrogen productionSulfide nanoparticlesSelf-aggregationPhotosynthetic systemsEncapsulation strategyAerobic conditionsNatural aerobic conditionsIn situ biosynthesisHybrid systemCatalysisHydrogenGlobal energyNanoparticlesCellsSemiconductor
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Clinic Building
789 Howard Avenue, Fl 4th Floor, Rm CB408
New Haven, CT 06519