Thomas D'Hooghe, MD, PhD
Professor (Adjunct) of Obstetrics, Gynecology, and Reproductive SciencesAbout
Titles
Professor (Adjunct) of Obstetrics, Gynecology, and Reproductive Sciences
Education & Training
- PhD
- Leuven University (1994)
- MD
- Leuven University (1985)
Research
Research at a Glance
Publications Timeline
A big-picture view of Thomas D'Hooghe's research output by year.
14Publications
18Citations
Publications
2024
Therapeutic management in women with a diminished ovarian reserve: a systematic review and meta-analysis of randomized controlled trials
Conforti A, Carbone L, Di Girolamo R, Iorio G, Guida M, Campitiello M, Ubaldi F, Rienzi L, Vaiarelli A, Cimadomo D, Ronsini C, Longobardi S, D'Hooghe T, Esteves S, Alviggi C. Therapeutic management in women with a diminished ovarian reserve: a systematic review and meta-analysis of randomized controlled trials. Fertility And Sterility 2024 PMID: 39332623, DOI: 10.1016/j.fertnstert.2024.09.038.Peer-Reviewed Original ResearchAltmetricConceptsDiminished ovarian reserveLive birth rateOvarian reserveRandomized controlled trialsClinical management of womenHigher live birth ratesAssociated with higher live birth ratesMeta-analysis of randomized controlled trialsControlled trialsInvestigate adjuvant treatmentsManagement of womenLow-dose gonadotropinsLuteal phase stimulationBirth ratePOSEIDON criteriaCorifollitropin alfaAdjuvant treatmentGonadotropin regimensGnRH antagonistClomiphene citrateLuteinizing hormoneTherapeutic managementTestosterone supplementationClinical managementRandomized trialsGonadotropin Activity during Early Folliculogenesis and Implications for Polycystic Ovarian Syndrome and Premature Ovarian Insufficiency: A Narrative Review
Longobardi S, Klinger F, Zheng W, Campitiello M, D’Hooghe T, La Marca A. Gonadotropin Activity during Early Folliculogenesis and Implications for Polycystic Ovarian Syndrome and Premature Ovarian Insufficiency: A Narrative Review. International Journal Of Molecular Sciences 2024, 25: 7520. PMID: 39062762, PMCID: PMC11277126, DOI: 10.3390/ijms25147520.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsPolycystic ovary syndromePremature ovarian insufficiencyFollicle-stimulating hormoneEarly folliculogenesisOvarian reservePolycystic ovarian syndromeOvarian insufficiencyLuteinizing hormoneOvarian syndromePool of primordial folliclesFemale fertilityPrimordial follicle activationPrimordial follicle developmentStages of folliculogenesisResponse to gonadotropinsMolecular pathway alterationsInfluence of LHYears of ageGonadotropin-independentGonadotropin-dependentPrimordial folliclesAntral stageAntiepileptic treatmentPathway alterationsFolliculogenesisCirculating microRNAs as Non-Invasive Biomarkers in Endometriosis Diagnosis—A Systematic Review
Vanhie A, Caron E, Vermeersch E, O D, Tomassetti C, Meuleman C, Mestdagh P, D'Hooghe T. Circulating microRNAs as Non-Invasive Biomarkers in Endometriosis Diagnosis—A Systematic Review. Biomedicines 2024, 12: 888. PMID: 38672242, PMCID: PMC11048084, DOI: 10.3390/biomedicines12040888.Peer-Reviewed Original ResearchCitationsDose accuracy of the follitropin alfa pen injector 2.0, the follitropin alfa:lutropin alfa 2:1 combination pen injector 2.0 and the choriogonadotropin alfa pen injector 1.0 used for fertility treatment
Cottell E, Michalet D, Lispi M, Araujo T, Gleixner R, Longobardi S, D’Hooghe T. Dose accuracy of the follitropin alfa pen injector 2.0, the follitropin alfa:lutropin alfa 2:1 combination pen injector 2.0 and the choriogonadotropin alfa pen injector 1.0 used for fertility treatment. Expert Opinion On Drug Delivery 2024, 21: 337-346. PMID: 38299472, DOI: 10.1080/17425247.2024.2311127.Peer-Reviewed Original Research
2023
Response to Individualized vs. conventional ovarian stimulation for in vitro fertilization: a multicenter, randomized, controlled, assessor-blinded, phase 3 noninferiority trial
Longobardi S, D'Hooghe T. Response to Individualized vs. conventional ovarian stimulation for in vitro fertilization: a multicenter, randomized, controlled, assessor-blinded, phase 3 noninferiority trial. Fertility And Sterility 2023, 121: 706. PMID: 38147958, DOI: 10.1016/j.fertnstert.2023.12.024.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsHome Monitoring of Art Cycles
Zheng W, Gerris J, Dancet E, D'Hooghe T. Home Monitoring of Art Cycles. 2023, 539-546. DOI: 10.1201/9781003268611-49.Peer-Reviewed Original ResearchConceptsAssisted reproductive technologyControlled ovarian stimulationOvarian hyperstimulation syndromeHormone testClinic-based monitoringLoss of incomeHyperstimulation syndromeCycle monitoringOvarian responseOvarian stimulationSerum hormone assaysAssess ovarian responseReproductive technologyVaginal ultrasoundHealth approachHormone assaysPrevent complicationsBlood withdrawalTailored treatmentTele-counselingUltrasoundOffice hoursTreatmentIncomeEffectiveness of recombinant human FSH: recombinant human LH combination treatment versus recombinant human FSH alone for assisted reproductive technology in women aged 35–40 years
Bielfeld A, Schwarze J, Verpillat P, Lispi M, Fischer R, Hayward B, Chuderland D, D'Hooghe T, Krussel J. Effectiveness of recombinant human FSH: recombinant human LH combination treatment versus recombinant human FSH alone for assisted reproductive technology in women aged 35–40 years. Reproductive BioMedicine Online 2023, 48: 103725. PMID: 38593745, DOI: 10.1016/j.rbmo.2023.103725.Peer-Reviewed Original ResearchAltmetricConceptsAdvanced maternal ageWomen of advanced maternal ageR-hLHR-hFSHRecombinant human FSHLive birthsClinical pregnancyOvarian stimulationHuman FSHPost hoc analysis of womenRecombinant human LHLive birth rateNormal ovarian reserveNon-interventional studyAssisted reproductive technologyAnalysis of womenPost hoc analysisOvarian reserveMaternal ageEffects of treatmentHuman LHAlone groupPatient groupClinical trialsART treatmentImproving trustworthiness in research in Women's Health: A collective effort by OBGYN Editors
Berghella V, Aviram A, Chescheir N, de Costa C, Dicker P, Goggins A, Gupta J, D'Hooghe T, Odibo A, Papageorghiou A, Saade G, Geary M. Improving trustworthiness in research in Women's Health: A collective effort by OBGYN Editors. European Journal Of Obstetrics & Gynecology And Reproductive Biology 2023, 292: 71-74. PMID: 37976768, DOI: 10.1016/j.ejogrb.2023.11.001.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsPreface: Health economics and outcomes research in reproductive medicine: Methods and comparative effectiveness of treatment protocols
D'Hooghe T. Preface: Health economics and outcomes research in reproductive medicine: Methods and comparative effectiveness of treatment protocols. Best Practice & Research Clinical Obstetrics & Gynaecology 2023, 92: 102424. PMID: 37952324, DOI: 10.1016/j.bpobgyn.2023.102424.Peer-Reviewed Original ResearchAltmetricPreface: Emerging importance of real world evidence in reproductive medicine
D'Hooghe T. Preface: Emerging importance of real world evidence in reproductive medicine. Best Practice & Research Clinical Obstetrics & Gynaecology 2023, 92: 102423. PMID: 37952325, DOI: 10.1016/j.bpobgyn.2023.102423.Peer-Reviewed Original ResearchAltmetric