Gordon Sze, MD
Professor Emeritus of Radiology and Biomedical ImagingCards
About
Research
Publications
2026
Enhanced Detection of Acute Ischemic Stroke With Low-Field MRI
Sorby-Adams A, Pinter N, Demopoulos A, Kirsch J, Jaikumar V, Nelson O, Bacchi S, Guo J, Parry B, Brigger H, Johnson I, de Havenon A, Sze G, O’Halloran R, Pitts J, Lee V, Muir K, Nimjee S, Siddiqui A, Keenan K, Rosen M, Iglesias J, Sheth K, Goldstein J, Kimberly W. Enhanced Detection of Acute Ischemic Stroke With Low-Field MRI. Stroke Vascular And Interventional Neurology 2026, 6: e002110. PMID: 41815314, PMCID: PMC12959426, DOI: 10.1161/svin.125.002110.Peer-Reviewed Original ResearchMagnetic resonance imagingAcute ischemic strokeDiffusion-weighted imagingIschemic strokeMD imagesLesion detectionSingle-directionLow-field magnetic resonance imagingPositive predictive valueDiagnosis of acute ischemic strokeSD imagesCut-pointsLow signal-to-noise ratioDetection of acute ischemic strokeClinically feasible time frameDetection of lesionsSignal-to-noise ratioDiagnostic confidenceC-arm systemDiagnostic accuracyPredictive valueStroke mimicsLesionsResonance imagingCooling systemDetecting patterns of atrophy in cognitively impaired individuals using portable, low-field MRI
Farnan A, Sorby-Adams A, Guo J, Dickson J, Gomez L, DeSenna A, Kirsch J, Smith J, Peasley E, Ford J, Payabvash S, Sze G, Fesharaki-Zadeh A, van Dyck C, Rosen M, Sheth K, Iglesias J, de Havenon A, Pozo A, Gomez-Isla T, Kimberly W. Detecting patterns of atrophy in cognitively impaired individuals using portable, low-field MRI. Imaging Neuroscience 2026, 4: imag.a.1075. PMID: 41503006, PMCID: PMC12770908, DOI: 10.1162/imag.a.1075.Peer-Reviewed Original ResearchMild cognitive impairmentBrain regionsBrain volumeCognitive impairmentPatterns of atrophyCognitively impaired individualsAlzheimer's diseaseNucleus accumbensAged subjectsVascular comorbiditiesNeuroimaging approachesLF-MRIRegional atrophyEvaluation of patientsAmygdalaLow-field MRIVentral diencephalonBrainCaudateImpaired individualsCortexLateral ventricleHealthy volunteersThird ventricleConventional MRI
2025
Predicting White Matter Hyperintensity: Leveraging Portable Magnetic Resonance Imaging for Accessible Brain Health Screening
Johnson I, Brigger H, Smith J, Peasley E, Champagne A, Littig L, Lalwani D, Sze G, Payabvash S, Safdar B, D'Onofrio G, Wira C, Iglesias J, Rosen M, Sorby-Adams A, Kimberly W, Sheth K, de Havenon A. Predicting White Matter Hyperintensity: Leveraging Portable Magnetic Resonance Imaging for Accessible Brain Health Screening. American Journal Of Neuroradiology 2025, 46: 1786-1792. PMID: 40081846, PMCID: PMC12406303, DOI: 10.3174/ajnr.a8734.Peer-Reviewed Original ResearchWhite matter hyperintensitiesWMH measuresMagnetic resonance imagingConventional MRIScreening pilot programRisk factorsValidation cohortHigh-risk individualsAcute neurologic pathologyVascular risk factorsTertiary care hospitalSystolic blood pressure >Resonance imagingDevelopment cohortWhite matter hyperintensities burdensHealth screeningTobacco useBlood pressure >Emergency departmentCare hospitalPortable MRIRisk scoreScreening toolPilot programPrimary outcome
2024
Quantifying White Matter Hyperintensity and Brain Volumes in Heterogeneous Clinical and Low-Field Portable MRI
Laso P, Cerri S, Sorby-Adams A, Guo J, Mateen F, Goebl P, Wu J, Liu P, Li H, Young S, Billot B, Puonti O, Sze G, Payabavash S, DeHavenon A, Sheth K, Rosen M, Kirsch J, Strisciuglio N, Wolterink J, Eshaghi A, Barkhof F, Kimberly W, Iglesias J. Quantifying White Matter Hyperintensity and Brain Volumes in Heterogeneous Clinical and Low-Field Portable MRI. 2011 IEEE International Symposium On Biomedical Imaging: From Nano To Macro 2024, 00: 1-5. PMID: 40851670, PMCID: PMC12369672, DOI: 10.1109/isbi56570.2024.10635502.Peer-Reviewed Original Research
2023
Detection of Intracerebral Hemorrhage Using Low-Field, Portable Magnetic Resonance Imaging in Patients With Stroke
Mazurek M, Parasuram N, Peng T, Beekman R, Yadlapalli V, Sorby-Adams A, Lalwani D, Zabinska J, Gilmore E, Petersen N, Falcone G, Sujijantarat N, Matouk C, Payabvash S, Sze G, Schiff S, Iglesias J, Rosen M, de Havenon A, Kimberly W, Sheth K. Detection of Intracerebral Hemorrhage Using Low-Field, Portable Magnetic Resonance Imaging in Patients With Stroke. Stroke 2023, 54: 2832-2841. PMID: 37795593, PMCID: PMC11103256, DOI: 10.1161/strokeaha.123.043146.Peer-Reviewed Original ResearchA Novel Portable, Mobile MRI: Comparison with an Established Low-Field Intraoperative MRI System
Bossert S, Unadkat P, Sheth K, Sze G, Schulder M. A Novel Portable, Mobile MRI: Comparison with an Established Low-Field Intraoperative MRI System. Asian Journal Of Neurosurgery 2023, 18: 492-498. PMID: 38152522, PMCID: PMC10749856, DOI: 10.1055/s-0043-1760857.Peer-Reviewed Original ResearchBrain imaging with portable low-field MRI
Kimberly W, Sorby-Adams A, Webb A, Wu E, Beekman R, Bowry R, Schiff S, de Havenon A, Shen F, Sze G, Schaefer P, Iglesias J, Rosen M, Sheth K. Brain imaging with portable low-field MRI. Nature Reviews Bioengineering 2023, 1: 617-630. PMID: 37705717, PMCID: PMC10497072, DOI: 10.1038/s44222-023-00086-w.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSparse k-space dataK-space dataImage reconstructionUseful diagnostic imagesReconstruction algorithmLow power requirementsNew applicationsLF-MRIDiagnostic imagesNew approachNew opportunitiesHardwareConventional systemMachineOngoing developmentPower requirementsAlgorithmImagesTechnological innovationFurther innovationNoise cancellationNoise ratioTechnologyRequirementsInformation
2017
Apparent Diffusion Coefficient Value Changes and Clinical Correlation in 90 Cases of Cytomegalovirus-Infected Fetuses with Unremarkable Fetal MRI Results
Kotovich D, Guedalia JSB, Hoffmann C, Sze G, Eisenkraft A, Yaniv G. Apparent Diffusion Coefficient Value Changes and Clinical Correlation in 90 Cases of Cytomegalovirus-Infected Fetuses with Unremarkable Fetal MRI Results. American Journal Of Neuroradiology 2017, 38: 1443-1448. PMID: 28522662, PMCID: PMC7959907, DOI: 10.3174/ajnr.a5222.Peer-Reviewed Original ResearchConceptsCytomegalovirus-infected fetusesFetal MRVABS-II scoresADC valuesCytomegalovirus infectionFetal brainApparent diffusion coefficient (ADC) value changesNeurocognitive assessmentIntrauterine cytomegalovirus infectionCase of cytomegalovirusMost brain areasFetal MR imagingVABS-IIDiffuse reductionIntrauterine infectionNeurodevelopmental impairmentClinical findingsBasal gangliaUnremarkable findingsClinical correlationBrain evaluationRetrospective analysisAge control groupTemporal lobeMRI results
2016
Prenatal stress alters amygdala functional connectivity in preterm neonates
Scheinost D, Kwon SH, Lacadie C, Sze G, Sinha R, Constable RT, Ment LR. Prenatal stress alters amygdala functional connectivity in preterm neonates. NeuroImage Clinical 2016, 12: 381-388. PMID: 27622134, PMCID: PMC5009231, DOI: 10.1016/j.nicl.2016.08.010.Peer-Reviewed Original ResearchConceptsPrenatal stress exposurePreterm neonatesPreterm birthPrenatal stressStress exposureTerm controlsFunctional connectivityAmygdala connectivityNeuropsychiatric disordersResting-state functional magnetic resonance imagingPrenatal stress altersEarly life stressFunctional magnetic resonance imagingMagnetic resonance imagingPeristriate cortexPrenatal exposureHigh riskMaternal stressIndependent cohortNeonatesLeft amygdalaSubcortical regionsResonance imagingAmygdalaCohort
2015
Glyburide Advantage in Malignant Edema and Stroke (GAMES-RP) Trial: Rationale and Design
Sheth KN, Elm JJ, Beslow LA, Sze GK, Kimberly WT. Glyburide Advantage in Malignant Edema and Stroke (GAMES-RP) Trial: Rationale and Design. Neurocritical Care 2015, 24: 132-139. PMID: 26268138, DOI: 10.1007/s12028-015-0189-7.Peer-Reviewed Original ResearchConceptsAdverse eventsCerebral edemaContinuous infusionHigh riskAnterior circulation ischemic strokeDiffusion-weighted image (DWI) lesionsAnterior circulation infarctionLarge territory infarctionMalignant cerebral edemaPrimary efficacy outcomeSerious adverse eventsLarge hemispheric strokeYears of ageStudy infusionEfficacy outcomesTerritory infarctionIschemic strokeNeurological deteriorationRankin ScaleSymptom onsetDecompressive craniectomyMulticenter trialBrain edemaHemispheric strokeStroke trials
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Radiology & Biomedical Imaging; Neuroradiology
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Diagnostic Radiology
- Certification Organization
- AB of Radiology
- Original Certification Date
- 1985
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Radiology & Biomedical Imaging
PO Box 208042, Tompkin's East 2
New Haven, CT 06520-8042
United States
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