Anuradha Singh, MD, FAAN (Neurology), FAES
she/her/hers
Clinical Chief of Epilepsy, Department of Neurology and Director of the Comprehensive Epilepsy CenterCards
About
Research
Overview
Medical Research Interests
Epilepsy; Health Care Quality, Access, and Evaluation; Seizures
Publications
2024
Neuropsychiatric complications of coronavirus disease 2019: Mount Sinai Health System cohort study
Gururangan K, Peschansky V, Van Hyfte G, Agarwal P, Blank L, Mathew B, Goldstein J, Kwon C, McCarthy L, Cohen A, Chan A, Deng P, Dhamoon M, Gutzwiller E, Hao Q, He C, Klenofsky B, Lemus H, Marcuse L, Navis A, Heredia Nunez W, Luckey M, Schorr E, Singh A, Tantillo G, Ufongene C, Young J, Balchandani P, Festa J, Naasan G, Charney A, Nadkarni G, Jetté N. Neuropsychiatric complications of coronavirus disease 2019: Mount Sinai Health System cohort study. Journal Of Neurology 2024, 271: 3991-4007. PMID: 38656620, DOI: 10.1007/s00415-024-12370-9.Peer-Reviewed Original ResearchConceptsIn-hospital mortalityAssociated with lower oddsHigher odds of mortalityResultsOur study cohortElectronic medical record databaseChart reviewNeuropsychiatric complicationsNew York City health systemOdds of mortalityAssociated with in-hospital mortalityMultivariate logistic regressionMedical record databaseHealth systemLower oddsHigher oddsIndividual chart reviewSerum inflammatory marker levelsCohort studyPre-existing comorbiditiesRecord databaseCOVID-19Logistic regressionTreated with anticoagulationInflammatory marker levelsComplication of coronavirus diseaseElevated phase amplitude coupling as a depression biomarker in epilepsy
Young J, Chan A, Jette N, Bender H, Saad A, Saez I, Panov F, Ghatan S, Yoo J, Singh A, Fields M, Marcuse L, Mayberg H. Elevated phase amplitude coupling as a depression biomarker in epilepsy. Epilepsy & Behavior 2024, 152: 109659. PMID: 38301454, PMCID: PMC10923038, DOI: 10.1016/j.yebeh.2024.109659.Peer-Reviewed Original ResearchBeck Depression Inventory-IIPhase-amplitude couplingComorbid depressionAssessment of depressive symptomsBeck Depression Inventory-II scoresAssociated with comorbid depressionAnterior cingulate cortexEpilepsy patientsAmplitude couplingPre-operative assessmentElevated phase-amplitude couplingSpectral powerOrbitofrontal cortexCingulate cortexPrimary depressionCase-control comparisonDepressive symptomsBrain regionsBrain activityDepression biomarkersAdult epilepsy patientsDepressionBrain recordingsPatient studiesTreatment targetHealth care access, psychosocial outcomes and mental health in adults living with epilepsy during the COVID-19 pandemic
Mc Carthy L, Mathew B, Blank L, Van Hyfte G, Gotlieb E, Goldstein J, Agarwal P, Kwon C, Singh A, Fields M, Marcuse L, Yoo J, Sivarak E, Gururangan K, Navis A, Jetté N. Health care access, psychosocial outcomes and mental health in adults living with epilepsy during the COVID-19 pandemic. Epilepsy & Behavior 2024, 151: 109617. PMID: 38219607, DOI: 10.1016/j.yebeh.2023.109617.Peer-Reviewed Original ResearchConceptsPatient Health Questionnaire-9Generalized Anxiety Disorder-7Psychosocial outcomesMental healthHealthcare accessCancelled visitsCross-sectional study of adultsHealth care accessCOVID-19 pandemicMental health comorbiditiesPoor mental healthSocial support issuesPoor psychosocial outcomesSymptoms of anxietyCross-sectional studyStudy of adultsCare accessPsychosocial supportHealth comorbiditiesModerate/severe depressionHealth systemTelehealth visitsNeurological carePLWEStandardized questionnaire
2023
Older adults with epilepsy and COVID-19: Outcomes in a multi-hospital health system
Ufongene C, Van Hyfte G, Agarwal P, Goldstein J, Mathew B, Navis A, McCarthy L, Kwon C, Gururangan K, Balchandani P, Marcuse L, Naasan G, Singh A, Young J, Charney A, Nadkarni G, Jette N, Blank L, Group S. Older adults with epilepsy and COVID-19: Outcomes in a multi-hospital health system. Seizure 2023, 114: 33-39. PMID: 38039805, PMCID: PMC10841585, DOI: 10.1016/j.seizure.2023.11.018.Peer-Reviewed Original ResearchConceptsInternational Classification of DiseasesLength of stayOlder adultsDischarge dispositionHigher in-hospital mortalityHealth systemIn-hospital deathIn-hospital mortalityMulti-hospital health systemOdds of in-hospital deathAssociated with increased oddsAssociated with increased odds of in-hospital deathNew York health systemMultivariate logistic regression modelClassification of DiseasesConsecutive older patientsAssociated with higher in-hospital mortalityLogistic regression modelsCompare in-hospital outcomesFactors associated with mortalityNon-routine discharge dispositionAssociated with higher ratesOlder peopleInternational ClassificationAdmitted with COVID-19Responsive Neurostimulation for People With Drug-Resistant Epilepsy and Autism Spectrum Disorder
Fields M, Marsh C, Eka O, Johnson E, Marcuse L, Kwon C, Young J, LaVega-Talbott M, Kurukumbi M, Von Allmen G, Zempel J, Friedman D, Jette N, Singh A, Yoo J, Blank L, Panov F, Ghatan S. Responsive Neurostimulation for People With Drug-Resistant Epilepsy and Autism Spectrum Disorder. Journal Of Clinical Neurophysiology 2023, 41: 64-71. PMID: 35512185, PMCID: PMC10756699, DOI: 10.1097/wnp.0000000000000939.Peer-Reviewed Original ResearchConceptsDrug-resistant epilepsySuper respondersSeizure reductionPromising surgical optionResponsive neurostimulator systemRNS SystemAutism spectrum disorderSurgical candidatesSurgical evaluationSurgical optionsMulticenter studySpectrum disorderGeneral populationResponsive neurostimulationPatientsResponse rateSmall cohortEpilepsyNeurostimulator systemHigh rateRespondersDescriptive statisticsSystem placementBehavioral outcomesDisordersA multicenter retrospective study of patients treated in the thalamus with responsive neurostimulation
Fields M, Eka O, Schreckinger C, Dugan P, Asaad W, Blum A, Bullinger K, Willie J, Burdette D, Anderson C, Quraishi I, Gerrard J, Singh A, Lee K, Yoo J, Ghatan S, Panov F, Marcuse L. A multicenter retrospective study of patients treated in the thalamus with responsive neurostimulation. Frontiers In Neurology 2023, 14: 1202631. PMID: 37745648, PMCID: PMC10516547, DOI: 10.3389/fneur.2023.1202631.Peer-Reviewed Original ResearchAnterior thalamic nucleiSerious adverse eventsGlobal Clinical Impression ScaleVagal nerve stimulationDrug-resistant epilepsyDeep brain stimulationAdverse eventsMost patientsResponsive neurostimulationSeizure reductionResective surgeryResistant epilepsyImpression ScaleSide effectsMedian baseline seizure frequencyDrug-resistant epilepsy patientsRare serious adverse eventsAnti-seizure medicationsDifferent epilepsy centersMeaningful seizure reductionMedian seizure reductionMedication regimen changesBaseline seizure frequencyMulticenter retrospective studyRetrospective multicenter studyIn‐hospital outcomes in patients with and without epilepsy diagnosed with COVID‐19—A cohort study
Ufongene C, Van Hyfte G, Agarwal P, Blank L, Goldstein J, Mathew B, Lin J, Navis A, McCarthy L, Gururangan K, Peschansky V, Kwon C, Cohen A, Chan A, Dhamoon M, Deng P, Gutzwiller E, Hao Q, He C, Nunez W, Klenofsky B, Lemus H, Marcuse L, Roberts M, Schorr E, Singh A, Tantillo G, Young J, Balchandani P, Festa J, Naasan G, Charney A, Nadkarni G, Jetté N. In‐hospital outcomes in patients with and without epilepsy diagnosed with COVID‐19—A cohort study. Epilepsia 2023, 64: 2725-2737. PMID: 37452760, DOI: 10.1111/epi.17715.Peer-Reviewed Original ResearchConceptsLength of stayNon-routine dischargeCharlson Comorbidity IndexIn-hospital outcomesHigher Charlson comorbidity indexFactors associated with higher oddsIntensive care unitInternational Classification of DiseasesOlder ageAssociated with COVID-19 mortalityRegression modelsClassification of DiseasesDecreased LOSLonger length of stayLogistic regression modelsAssociated with mortalityHealth systemOrdinary least squares regression modelsCOVID-19 mortalityOlder adultsRetrospective study of patientsInternational ClassificationHigher oddsMulticenter health systemEvaluate in-hospital outcomesNeuroimaging findings and neurological manifestations in hospitalized COVID-19 patients: Impact of cancer and ventilatory support status
McCarthy L, Khegai O, Goldstein J, Belani P, Pawha P, Kihira S, Mathew B, Gururangan K, Hao Q, Singh A, Navis A, Delman B, Jette N, Balchandani P. Neuroimaging findings and neurological manifestations in hospitalized COVID-19 patients: Impact of cancer and ventilatory support status. PLOS ONE 2023, 18: e0283614. PMID: 36961861, PMCID: PMC10038284, DOI: 10.1371/journal.pone.0283614.Peer-Reviewed Original ResearchConceptsHospitalized COVID-19 patientsMagnetic resonance imagingVentilatory supportNeurological manifestationsCOVID-19 patientsNeuroimaging findingsSupport statusImpact of cancerPolymerase chain reaction-confirmed COVID-19Mount Sinai Health SystemNon-cancer patientsAssociated with neurological manifestationsRetrospective observational studySinai Health SystemClinical neurological manifestationsHealth systemCentral nervous systemCOVID-19 cohortMorbidity associated with COVID-19Cancer statusAcute/subacute infarctionProthrombotic stateCOVID-19Systemic illnessFocal weakness
2022
Neuroimaging Findings & Neurological Symptoms in COVID-19 Patients with & without Cancer: A Retrospective Multi-Center Observational Study
McCarthy L, Khegai O, Goldstein J, Belani P, Pawha P, Kihira S, Mathew B, Gururangan K, Hao Q, Singh A, Navis A, Delman B, Jette N, Balchandani P. Neuroimaging Findings & Neurological Symptoms in COVID-19 Patients with & without Cancer: A Retrospective Multi-Center Observational Study. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2022 DOI: 10.58530/2022/0734.Peer-Reviewed Original ResearchAssociated with neuroimaging abnormalitiesNeuroimaging abnormalitiesCOVID-19 patientsNeurological symptomsRetrospective multi-center observational studyNeurological manifestationsHospitalized COVID-19 patientsNeuroimaging findingsSignal hyperintensitiesMulti-center observational studyAcute/subacute infarctionNeuroimagingRetrospective analysisUltrahigh-Field 7T MRI of the Brain of COVID-19 Patients with Neurological Symptoms: An Initial Study
Rashid S, Khegai O, Jette N, Belani P, Pawha P, Saju S, Navis A, Mathew B, Goldstein J, Gururangan K, Hao Q, Singh A, Becker J, Delman B, Balchandani P. Ultrahigh-Field 7T MRI of the Brain of COVID-19 Patients with Neurological Symptoms: An Initial Study. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2022 DOI: 10.58530/2022/2206.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
Clinical Care
Overview
Anuradha Singh, MD, is a neurologist who specializes in epilepsy and seizures. She is the clinical chief and director of the Yale Comprehensive Epilepsy Center.
As a professor of neurology and neurosurgery at Yale School of Medicine, Dr. Singh is involved in research aimed at enhancing health care quality and access for epilepsy patients. She has published extensively on neurological cases and has shared her insights at numerous professional conferences and educational symposia. Her research contributes to a deeper understanding of epilepsy and the development of innovative treatment strategies.
Also passionate about education and mentorship, Dr. Singh has been instrumental in training medical students, residents, and fellows, earning several teaching awards for her commitment to developing future leaders in neurology.
Dr. Singh completed her medical training at Lady Hardinge Medical College in India. She pursued her neurology residency and a clinical neurophysiology/EEG fellowship at NYU School of Medicine.
Clinical Specialties
Epilepsy & Seizures; Neurology
Fact Sheets
Epilepsy
Learn More on Yale MedicineEpilepsy in Children and Teens
Learn More on Yale MedicinePediatric Sepsis
Learn More on Yale Medicine
Yale Medicine News
Get In Touch
Contacts
Appointment Number
Mailing Address
Yale University
15 York Street
New Haven, Connecticut 06510
United States
Administrative Support
Locations
Lippard Laboratory of Clinical Investigation (LLCI)
Academic Office
15 York Street
New Haven, CT 06510
Patient Care Locations
Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.