Zhonghua Tang
Research Associate 1 MSCards
About
Research
Publications
2025
Distinct transcriptional and epigenomic programs define Hofbauer cells in term placenta
Baráth B, Bojcsuk D, Bene K, Caballero-Sánchez N, Cseh T, de Freitas J, Tzerpos P, Toth M, Tang Z, Guller S, Krasznai Z, Neuperger P, Szebeni G, Nagy G, Deli T, Nagy L. Distinct transcriptional and epigenomic programs define Hofbauer cells in term placenta. JCI Insight 2025, 11: e195801. PMID: 41433105, PMCID: PMC12892902, DOI: 10.1172/jci.insight.195801.Peer-Reviewed Original ResearchRole of Serotonin on Gene Expression and Physiology in Human Cytotrophoblasts and Placenta
Morris N, Guller S, Tang Z, Zhang Y, Siegman E, Milano K, Rudnick G, Kliman H. Role of Serotonin on Gene Expression and Physiology in Human Cytotrophoblasts and Placenta. Endocrinology 2025, 166: bqaf124. PMID: 40898405, PMCID: PMC12399332, DOI: 10.1210/endocr/bqaf124.Peer-Reviewed Original ResearchThis study investigates how serotonin affects placental gene expression and growth, showing its critical role in embryonic development via nuclear protein modification called serotonylation.
2023
Leptin-Mediated Induction of IL-6 Expression in Hofbauer Cells Contributes to Preeclampsia Pathogenesis
Ozmen A, Nwabuobi C, Tang Z, Guo X, Larsen K, Guller S, Blas J, Moore M, Kayisli U, Lockwood C, Guzeloglu-Kayisli O. Leptin-Mediated Induction of IL-6 Expression in Hofbauer Cells Contributes to Preeclampsia Pathogenesis. International Journal Of Molecular Sciences 2023, 25: 135. PMID: 38203306, PMCID: PMC10778808, DOI: 10.3390/ijms25010135.Peer-Reviewed Original Research