Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsSven-Eric Jordt, PhD
he/him/his
Associate Professor of Anesthesiology, Pharmacology & Cancer Biology, University Program of Environmental Health (UPEH), Duke University School of MedicineAbout
Research
Publications
2025
Modeling functional responses to pollutant exposure using modular hydrogel supported vascularized alveolosphere-on-a-chip
Madhurakkat Perikamana S, Kumar V, Mogha P, Duncan L, Angel N, Tata A, Jabba S, Jordt S, Tata P, Varghese S. Modeling functional responses to pollutant exposure using modular hydrogel supported vascularized alveolosphere-on-a-chip. Biomaterials Science 2025 PMID: 40960519, PMCID: PMC12442856, DOI: 10.1039/d5bm00552c.Peer-Reviewed Original ResearchExtracellular matrix-based hydrogelsLow Young's modulusExtracellular matrixModular hydrogelsYoung's modulusHydrogelsMicrofluidic devicesExtracellular matrix proteinsAlveolar type 2Cellular contractilityMatrix stiffnessSize distributionDrug responseThree-dimensional cultureDisease mechanismsMatrixLung biologyAlveolar type 2 cellsAT2 cellsResponse to pollutant exposureCellsDrug discoveryLung fibroblastsMatrix degradationModulusPrevalence of Artificial Sweetener Neotame in US-Marketed Disposable E-Cigarettes
Erythropel H, Jabba S, Mellinghoff R, Garcia-Gallet V, Silinski P, Zimmerman J, Jordt S. Prevalence of Artificial Sweetener Neotame in US-Marketed Disposable E-Cigarettes. JAMA 2025, 334: 448-449. PMID: 40455485, PMCID: PMC12131167, DOI: 10.1001/jama.2025.7398.Peer-Reviewed Original ResearchProteomics, Redox Proteomics, and Metabolomics Profiling of Phosgene-induced Lung Injury in a Murine Model
Clair G, Day N, Daly J, Ushakumary M, Jordt S, Achanta S, Lin V. Proteomics, Redox Proteomics, and Metabolomics Profiling of Phosgene-induced Lung Injury in a Murine Model. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a2448-a2448. DOI: 10.1164/ajrccm.2025.211.abstracts.a2448.Peer-Reviewed Original ResearchAn Acute Porcine Phosgene Pulmonary Injury Model: Potential Biomarkers and Drug Targets
Achanta S, Jordt S, Foster M, Clair G, Lin V, Holmes W. An Acute Porcine Phosgene Pulmonary Injury Model: Potential Biomarkers and Drug Targets. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a4257-a4257. DOI: 10.1164/ajrccm.2025.211.abstracts.a4257.Peer-Reviewed Original ResearchProinflammatory Pulmonary Effects of SARS-CoV-2 Main Protease in Mice and Human Bronchial Epithelial Cells
Caceres A, Jabba S, Jordt S. Proinflammatory Pulmonary Effects of SARS-CoV-2 Main Protease in Mice and Human Bronchial Epithelial Cells. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a6597-a6597. DOI: 10.1164/ajrccm.2025.211.abstracts.a6597.Peer-Reviewed Original Research6-methyl Nicotine in Electronic Cigarettes: Chemical Analysis and Toxicological Properties
Jordt S, Caceres A, Silinski P, Jabba S. 6-methyl Nicotine in Electronic Cigarettes: Chemical Analysis and Toxicological Properties. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a7552-a7552. DOI: 10.1164/ajrccm.2025.211.abstracts.a7552.Peer-Reviewed Original ResearchTransient Receptor Potential channels (TRP) in GtoPdb v.2025.1
Blair N, McKemy D, Nilius B, Oancea E, Owsianik G, Riccio A, Sah R, Stotz S, Tian J, Tong D, Vriens J, Wu L, Xu H, Yang F, Yang W, Yue L, Liu Q, Liu B, Caceres A, Carvacho I, Chaudhuri D, Clapham D, De Clercq K, Delling M, Doerner J, Fan L, Grimm C, Ha K, Hu M, Jabba S, Jordt S, Julius D, Kahle K, Zhu M. Transient Receptor Potential channels (TRP) in GtoPdb v.2025.1. IUPHAR/BPS Guide To Pharmacology CITE 2025, 2025 DOI: 10.2218/gtopdb/f78/2025.1.Peer-Reviewed Original ResearchTRPC channelsTransient receptor potential channelsCongenital stationary night blindnessCalcium-activated cationStore-operated channelsAdenosine diphosphate riboseNumerous splice variantsNMDA receptorsActivate TRPA1Intracellular ATP levelsCation channelsChannel activityMicromolar concentrations of La3+Mucolipidosis type IVNeurodegenerative disorder mucolipidosis type IVDepletion of intracellular calcium storesTRP channelsRegulation of Ca2+ entryAssociated with conduction defectsDetection of noxious heatDevelopment of heat hyperalgesiaDevelopment of thermal hyperalgesiaDynamic intracellular vesicular structuresExtra-synaptic NMDA receptorsInvolvement of TRP channelsPharmacological Modulations of MRGPRX4 by Sensory Cooling Agents (Abstract ID: 161612)
Adinew G, Jordt S, Jabba S. Pharmacological Modulations of MRGPRX4 by Sensory Cooling Agents (Abstract ID: 161612). Journal Of Pharmacology And Experimental Therapeutics 2025, 392: 100676. DOI: 10.1016/j.jpet.2024.100676.Peer-Reviewed Original ResearchMarketing for Sensa: a ‘zero nicotine vapor product’ from a major tobacco company
Robichaud M, Talbot E, Ganz O, Mercincavage M, Erythropel H, Zimmerman J, Jabba S, Jordt S, Delnevo C. Marketing for Sensa: a ‘zero nicotine vapor product’ from a major tobacco company. Tobacco Control 2025, tc-2024-059074. PMID: 39956632, PMCID: PMC12354010, DOI: 10.1136/tc-2024-059074.Peer-Reviewed Original ResearchCalifornia’s Visionary Tobacco Bill—Will the FDA Follow?
Jordt S, Jabba S. California’s Visionary Tobacco Bill—Will the FDA Follow? JAMA 2025, 333: 285-286. PMID: 39621329, PMCID: PMC12132922, DOI: 10.1001/jama.2024.22986.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
News
News
- August 07, 2024
Novel E-Cigarette Products Marketed to Contain Nicotine Analogs Instead of Nicotine Show Discrepancies Between Label Information and Contents
- June 03, 2024Source: Scientific American
How Tobacco Companies Use Chemistry To Get Around Menthol Bans
- September 27, 2023
$20M Federal Grant Renewed for Yale Tobacco Center of Regulatory Science
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