Tobacco Center of Regulatory Science
The Yale Tobacco Center of Regulatory Science (TCORS 1.0) was formed at Yale in 2013 under a five-year federal grant to research the influence of flavors, including menthol, on tobacco addiction. The work at Yale and 13 other federally funded research centers has provided science-based knowledge to the U.S. FDA, which regulates tobacco.
In September of 2018, the National Institute of Health and the U.S. Food and Drug Administration renewed a grant for the Yale Tobacco Center of Regulatory Science (TCORS 2.0) to continue to investigate the influence of flavors and sweeteners, and other constituents, on the appeal and addictive potential of traditional tobacco products and newer products like e-cigarettes.
With the overarching goal of reducing appeal and addiction to tobacco products, the Yale TCORS 2.0 will conduct detailed evaluations of the influence of flavors and sweeteners on initiation, continued use and addiction and harm reduction from tobacco products. Cohesive and hypothesis driven, our research incorporates multiple methods and disciplines. The multidisciplinary team includes experts in sensory perception, tobacco addiction, adolescent tobacco use, menthol and irritant receptor biology, nicotinic receptor biology, dopaminergic signaling in brain reward pathways, human behavioral pharmacology, assay and clinical pharmacokinetics of drugs of abuse, analytical chemistry, health economics and decision-making science, and tobacco regulation.
In addition, the center trains scientists, and provides pilot funding to stimulate research related to tobacco regulatory science.
Message to e-cigarette researchers
E-cigarette researchers: You may need to get FDA approval for the use of the e-cigarette as an investigational tobacco product. The FDA outlines, the proposed requirements for obtaining an ITP for all federally funded e-cigarette research. If you have any further questions please contact us.
Learn how you can participate in research studies sponsored by Yale TCORS investigators. Please contact the Center's office at 203-974-7591 or email email@example.com for more information.
Latest TCORS News
- February 16, 2023
Faculty Honored By New Haven County Medical Association
- January 13, 2023Source: Connecticut Public Radio
Why 25? Doctors warn against the negative impact of cannabis use on young adult brains
- November 04, 2022Source: Tobacco Control
Tobacco Promotion Restriction Policies on Social Media
- October 26, 2022
Yale Expert Leads Update of Nicotine Delivery Systems Policy
- September 26, 2022
Building Momentum: WHRY's Undergraduate Fellows Advance Women's Health