Sayed (Ausim) Azizi, MD, PhD, FANA
he/him/his
Cards
About
Research
Publications
2023
A role for the prefrontal cortex in reward, punishment, and animal behavior: an anatomical/functional framework
Azizi S. A role for the prefrontal cortex in reward, punishment, and animal behavior: an anatomical/functional framework. Neuroscience Letters 2023, 808: 137296. DOI: 10.1016/j.neulet.2023.137296.Peer-Reviewed Original Research
2022
Interdisciplinary patient-centred poststroke care in Follow-up After Stroke, Screening and Treatment (FASST) clinic model: a proof-of-concept pilot study
Kim M, Cleymaet S, Kim S, Andres J, Ruchalski C, Kim Y, Azizi S, Sharrief A, Naqvi I. Interdisciplinary patient-centred poststroke care in Follow-up After Stroke, Screening and Treatment (FASST) clinic model: a proof-of-concept pilot study. Integrated Healthcare Journal 2022, 4: e000118. PMID: 37440858, PMCID: PMC10327447, DOI: 10.1136/ihj-2021-000118.Peer-Reviewed Original Research
2021
Role of the cerebellum in the phenotype of neurodegenerative diseases: Mitigate or exacerbate?
Azizi S. Role of the cerebellum in the phenotype of neurodegenerative diseases: Mitigate or exacerbate? Neuroscience Letters 2021, 760: 136105. PMID: 34246702, DOI: 10.1016/j.neulet.2021.136105.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2020
Monoamines: Dopamine, Norepinephrine, and Serotonin, Beyond Modulation, “Switches” That Alter the State of Target Networks
Azizi S. Monoamines: Dopamine, Norepinephrine, and Serotonin, Beyond Modulation, “Switches” That Alter the State of Target Networks. The Neuroscientist 2020, 28: 121-143. PMID: 33292070, DOI: 10.1177/1073858420974336.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsNeurological injuries in COVID-19 patients: direct viral invasion or a bystander injury after infection of epithelial/endothelial cells
Azizi S, Azizi S. Neurological injuries in COVID-19 patients: direct viral invasion or a bystander injury after infection of epithelial/endothelial cells. Journal Of NeuroVirology 2020, 26: 631-641. PMID: 32876900, PMCID: PMC7465881, DOI: 10.1007/s13365-020-00903-7.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAngiotensin-Converting Enzyme 2BetacoronavirusBrainBrain DiseasesBystander EffectCoronavirus InfectionsCOVID-19Epithelial CellsGene Expression RegulationHost-Pathogen InteractionsHumansLungNeuronsOlfaction DisordersPandemicsPeptidyl-Dipeptidase APneumonia, ViralPulmonary EmbolismSARS-CoV-2Signal TransductionSpike Glycoprotein, CoronavirusStroke
2017
Synucleinopathies in neurodegenerative diseases: Accomplices, an inside job and selective vulnerability
Azizi S, Azizi S. Synucleinopathies in neurodegenerative diseases: Accomplices, an inside job and selective vulnerability. Neuroscience Letters 2017, 672: 150-152. PMID: 29217261, DOI: 10.1016/j.neulet.2017.12.003.Peer-Reviewed Original Research
2016
Milton Alter, MD, PhD (1929–2016)
Kelley R, Azizi S. Milton Alter, MD, PhD (1929–2016). Neurology 2016, 87: 976-977. DOI: 10.1212/wnl.0000000000003074.Peer-Reviewed Original ResearchCharacterizing absolute lymphocyte count profiles in dimethyl fumarate–treated patients with MS
Fox R, Chan A, Gold R, Phillips J, Selmaj K, Chang I, Novas M, Rana J, Marantz J, Ambler Z, Ehler E, Havrdova E, Meluzinova E, Rektor I, Talab R, Gold R, Hartung H, Csanyi A, Csiba L, Jakab G, Hintzen R, Polman C, Drozdowski W, Fryze W, Kochanowicz J, Kwiecinski H, Maciejek Z, Schimrigk S, Selmaj K, Szczudlik A, Wajgt A, Belova A, Boiko A, Elchaninov A, Kozlov V, Odinak M, Shvarkov S, Skoromets A, Stolyarov I, Vorobieva O, Zavalishin I, Hillert J, Olsson T, Kappos L, Eraksoy M, Karabudak R, Siva A, Giovannoni G, Hawkins C, Sharief M, Sharrack B, Confavreux C, Ware J, Barnett M, Paine M, Lechner-Scott J, Beran R, Chapman C, Schwartz R, Butzkueven H, Casse R, Macdonell R, Berger T, Fazekas F, Ransmayr G, Vass K, Belachew S, De Deyn P, Decoo D, Dubois B, Medaer R, Seeldrayers P, Sindic C, Gaer L, Vanopdenbosch L, Grgic S, Bar-Or A, Bhan V, Bouchard J, Christie S, Grammond P, Jacques F, Veloso F, Vorobeychik G, Brinar V, Demarin V, Rudež J, Soldo-Butković S, Vurdelja R, Ambler Z, Doležil D, Havrdova E, Kanovsky P, Meluzinova E, Nova'k J, Rektor I, Skoda O, Duchcovská M, Camu W, Antoanela P, Coman I, Confavreux C, Edan G, Gout O, Lebrun-Frenay C, Papeix A, Vermersch P, Bachus-Banaschak K, Berghoff M, Bethke F, Boldt H, Chan A, Diener H, Eisensehr I, Emrich P, Griewing B, Haas J, Heesen C, Hoffmann F, Hufnagel A, Heidenreich F, Kleiter I, Lüer W, Marckmann-Böenke S, Marziniak M, Stangel M, Oschmann P, Rosenkranz T, Schneider H, Siefjediers V, Springub J, Stangel M, Stögbauer F, Bergh F, Tiel-Wilck K, Tinschert K, Grigoriadis N, Karageorgiou C, Kyritsis A, Papadimitriou A, Thomaides T, Vlaikidis N, Salguero Gonzalez L, Chon D, Ordoñez Sarg H, Agrawal C, Behari M, Cu V, Dwivedee S, Kothari S, Kulkarni R, Kushwaha S, Meena A, Mehndiratta M, Chandra Mukherjee S, Pandit L, Shah A, Shukla R, Vijayan K, Achiron A, Flechter S, Milo R, Vaknin-Dembinsky A, Pozzilli C, Daskalovska V, Castro Farfan F, Rangel Guerra R, Leyva I, Oropeza de Alba J, Revilla R, Rivera J, Gavriliuc M, Groppa S, Odainic O, Sanders E, Hupperts R, Mason D, Timmings P, Willoughby E, Czlonkowska A, Dorobek M, Drozdowski W, Fryze W, Hertmanowska H, Kleczkowska M, Kochanowicz J, Kwieciński H, Nowacki P, Podemski R, Potemkowski A, Selmaj K, Stelmasiak Z, Wajgt A, Zielinski T, Daskalovska V, Bajenaru A, Muresanu F, Nica S, Simu M, Drakulić S, Nadj C, Obradovic D, Vojinovic S, Turčáni P, Kahancová E, Kurca E, Lisý L, Krajnak V, Badenhorst F, Green J, Heckmann J, Isaacs M, Kappos L, Linnebank M, Müller S, Buchakchyys'ka N, Goloborodko A, Kobys T, Lebedynets V, Lytvynenko N, Nehrych T, Pasyura I, Ryabichenko T, Voloshina N, Duddy M, Hawkins C, Nicholas R, Palace J, Sharrack B, Silber E, Turner B, Camac A, Chumley W, Crayton H, Dixit S, Edwards K, English J, Freedman S, Gordon N, Gazda S, Goldstick L, Gottschalk P, Grazioli E, Grainger W, Green B, Grelinger B, Gudesblatt M, Gupta A, Hayat G, Hendin B, Henson L, Hentati A, Herrman C, Itkin A, Janus T, Kasper L, Lathi E, Mowry E, Parry G, Perel A, Rao T, Riskind P, Rizvi S, Rossman H, Scott T, Shafer S, Storey J, Thrower B, Rossen M, Tosches W, Trefts L, Turel A, Weinstock-Guttman B, Gold R, Kappos L, Arnold D, Bar-Or A, Giovannoni G, Selmaj K, Dawson K, Gallacher P, Milla C, Yang M, Antel J, Bakris G, Chung R, Kowey P, Polman C, Richert J, Seibert B, Ware J, Brandes D, Brassat D, Cohen B, Diem R, Goldman M, Herndon R, Miller A, Tumani H, Kneebone C, Fedulau A, Likhachev S, Mikhailova E, Naumova H, Decoo D, Sindic C, Gaer L, Grgic S, Sinanovic O, Suljic E, Deleva N, Georgiev D, Haralanov L, Ivanova S, Manchev I, Minchev D, Stamenova P, Tournev I, Vacheva E, Zahariev Z, Howell R, Vindas A, Bar-Or A, Blevins G, Kremenchutzky M, Veloso F, Witt N, Habek M, Rudež J, Soldo-Butković S, Vurdelja R, Doležil D, Havrdova E, Nova'k J, Vaclavik D, Antsov K, Gross-Paju K, Haldre S, Palu A, Toomsoo T, Al Khedr A, Camu W, De Seze J, Debouverie M, Defer G, Labauge P, Moreau T, Rumbach L, Angnstwurm K, Benes H, Berthele A, Boldt H, Christopher A, Derfuß T, Eisensehr I, Emrich P, Feneberg W, Hoffmann F, Hohlfeld R, Hüntemann R, Kallmann B, Kieseier B, Kleiter I, Landefeld H, Lüer W, Masri S, Mäurer M, Nelles G, Oschmann P, Paschen C, Reifschneider G, Sailer M, Schimrigk S, Spiegel-Meixensberger M, Steinbrecher A, Storch-Hagenlocher B, Tackenberg B, Tiel-Wilck K, Karageorgiou C, Papathanasopoulos P, Thomaides T, Vlaikidis N, Arjundas D, Behari M, Shah S, Ghosh A, Ghosh P, Ichaporia N, Khurana D, Kulkarni R, Mehndiratta M, Mehta N, Misra U, Mukherji J, Nellikunja S, Radhakrishnan S, Salem A, Sethi P, Singh G, Lines C, Singh M, Singh Y, Srinivasa R, Vijayan K, Hutchinson M, Sweeney B, Gilad R, Shahien R, Metra M, Paegle A, Daskalovska V, Delgado C, Escamilla J, Estañol B, Lopez N, Macias M, Punzo G, Quiñones S, Renteria M, Santos C, Gavriliuc M, Groppa S, Odainic O, Timmings P, Czlonkowska A, Dorobek M, Drozdowski W, Fryze W, Hertmanowska H, Kaminska A, Kapelusiak-Pielok M, Kleczkowska M, Kochanowicz J, Kwieciński H, Losy J, Nowacki P, Nyka W, Pierzchala K, Podemski R, Potemkowski A, Selmaj K, Stelmasiak Z, Szczudlik A, Tutaj A, Wajgt A, Zielinski T, Chinea A, Balasa R, Ionescu-Dimancea V, Mihancea P, Popescu C, Protosevici L, Drakulić S, Nadj C, Raicevic R, Vojinovic S, Kahancová E, Kurca E, Lisý L, Turčáni P, Arroyo R, Fernández O, Guijarro C, Izquierdo G, Montalbán X, Oreja-Guevara C, Prieto J, Lopez F, Buchakchyys'ka N, Chmyr G, Goloborodko A, Grytsay N, Kobys T, Kushnir G, Lebedynets V, Lytvynenko N, Moskovko S, Nehrych T, Palamar B, Pasyura I, Ryabichenko T, Voloshina N, Apperson M, Applebee A, Asher S, Ayala R, Ayres D, Azizi S, Baker M, Bauer B, Bomprezzi R, Buckler R, Carlini W, Cohan S, Crowell G, Edwards K, Eubank G, Felton W, Fodor P, Foley J, Ford C, Forester M, Fox E, Fox R, Freedman S, Garmany G, Gazda S, Giang D, Glaun B, Gold S, Gottesman M, Gudesblatt M, Herbert J, Herskowitz A, Honeycutt W, Huddlestone J, Hull R, Hunter S, Hutton G, Jacobs D, Janicki M, Khatri B, Kinkel R, Kita M, Krolczyk S, Krupp L, LaGanke C, Levin M, Licht J, Luzzio C, Lynch S, Mattson D, Mikol D, Miller T, Minagar A, Mitchell G, Moses H, Negroski D, Newman S, Pardo G, Patel M, Perel A, Phillips J, Picone M, Rammohan K, Rao T, Rinker J, Sadiq S, Schaeffer J, Sheremata W, Shin R, Shubin R, Silverman S, Smith R, Stein L, Stein M, Steiner D, Steingo B, Sullivan H, Sunter W, Vaishnav A, Vasquez A, Voci J, Warach J, Weinstock-Guttman B, Williams M, Wray S, Fox R, Phillips J, Hutchinson M, Havrdova E, Kita M, Wilson K, Yang M, Dawson K, Antel J, Ware J, Polman C, Kowey P, Chung R, Bakris G, Richert J, Seibert B, Brandes D, Brassat D, Cohen B, Diem R, Goldman M, Herndon R, Miller A, Tumani H, Alfaro-Vidal T, Crespo C, Foster J, Hunter K, Garcia-Gomez A, MacManus D, Miller D, Santana V, Tozer D, Kingshott-Wheeler C, Yousry T. Characterizing absolute lymphocyte count profiles in dimethyl fumarate–treated patients with MS. Neurology Clinical Practice 2016, 6: 220-229. PMID: 27347439, PMCID: PMC4909524, DOI: 10.1212/cpj.0000000000000238.Peer-Reviewed Original ResearchIntracerebral hemorrhage with intraventricular extension and no hydrocephalus may not increase mortality or severe disability
Mahta A, Katz P, Kamel H, Azizi S. Intracerebral hemorrhage with intraventricular extension and no hydrocephalus may not increase mortality or severe disability. Journal Of Clinical Neuroscience 2016, 30: 56-59. PMID: 26972705, DOI: 10.1016/j.jocn.2015.11.028.Peer-Reviewed Original Research
2015
Effects of delayed-release dimethyl fumarate on MRI measures in the phase 3 CONFIRM study
Miller D, Fox R, Phillips J, Hutchinson M, Havrdova E, Kita M, Wheeler-Kingshott C, Tozer D, MacManus D, Yousry T, Goodsell M, Yang M, Zhang R, Viglietta V, Dawson K, Fox R, Phillips J, Hutchinson M, Havrdova E, Kita M, Wilson K, Yang M, Dawson K, Antel J, Ware J, Polman C, Kowey P, Chung R, Bakris G, Richert J, Seibert B, Brandes D, Brassat D, Cohen B, Diem R, Goldman M, Herndon R, Miller A, Tumani H, Alfaro-Vidal T, Crespo C, Foster J, Hunter K, Garcia-Gomez A, MacManus D, Miller D, Santana V, Tozer D, Wheeler-Kingshott C, Yousry T, Kneebone C, Fedulau A, Likhachev S, Mikhailova E, Naumova H, Decoo D, Gaer L, Sindic C, Grgic S, Sinanovic O, Suljic E, Deleva N, Georgiev D, Haralanov L, Ivanova S, Manchev I, Minchev D, Stamenova P, Tournev I, Vacheva E, Zahariev Z, Bar-Or A, Blevins G, Kremenchutzky M, Veloso F, Witt N, Vargas Howell R, Vindas A, Habek M, Rudež J, Soldo-Butković S, Vurdelja R, Doležil D, Havrdova E, Nova'k J, Vaclavik D, Antsov K, Gross-Paju K, Haldre S, Palu A, Toomsoo T, Al Khedr A, Camu W, Debouverie M, Defer G, De Seze J, Labauge P, Moreau T, Pelletier J, Rumbach L, Daskalovska V, Angnstwurm K, Benes H, Berthele A, Boldt H, Christopher A, Derfuß T, Eisensehr I, Emrich P, Feneberg W, Hoffmann F, Hohlfeld R, Hüntemann R, Kallmann B, Kieseier B, Landefeld H, Lüer W, Masri S, Nelles G, Oschmann P, Paschen C, Reifschneider G, Sailer M, Schimrigk S, Spiegel-Meixensberger M, Storch-Hagenlocher B, Tackenberg B, Tiel-Wilck K, Karageorgiou C, Papathanasopoulos P, Thomaides T, Vlaikidis N, Arjundas D, Behari M, Ghosh A, Ghosh P, Ichaporia N, Khurana D, Kulkarni R, Kumar S, Mehndiratta M, Mehta N, Misra U, Mukherji J, Nellikunja S, Salem A, Sethi P, Shah S, Singh G, Singh M, Singh Y, Srinivasa R, Vijayan K, Hutchinson M, Sweeney B, Gilad R, Shahien R, Paegle A, Delgado C, Escamilla J, Estañol B, Lopez M, Macias M, Punzo G, Quiñones S, Renteria M, Santos J, Gavriliuc M, Groppa S, Odainic O, Timmings P, Czlonkowska A, Dorobek M, Drozdowski W, Fryze W, Hertmanowska H, Kaminska A, Kapelusiak-Pielok M, Kleczkowska M, Kochanowicz J, Losy J, Nowacki P, Nyka W, Pierzchala K, Podemski R, Potemkowski A, Selmaj K, Stelmasiak Z, Szczudlik A, Tutaj A, Wajgt A, Zielinski T, Balasa R, Ionescu-Dimancea V, Mihancea P, Popescu C, Protosevici L, Miletić Drakulić S, Nadj C, Raicevic R, Vojinovic S, Kahancová E, Kurca E, Lisý L, Turčáni P, Arroyo R, Fernández O, Guijarro C, Izquierdo G, Lopez F, Montalbán X, Oreja-Guevara C, Prieto J, Buchakchyys'ka N, Chmyr G, Goloborodko A, Kobys T, Kushnir G, Lebedynets V, Lytvynenko N, Moskovko S, Nehrych T, Palamar B, Pasyura I, Ryabichenko T, Voloshina N, Apperson M, Applebee A, Asher S, Ayala R, Ayres D, Azizi S, Baker M, Bauer B, Bomprezzi R, Buckler R, Carlini W, Chinea A, Cohan S, Crowell G, Edwards K, Eubank G, Felton W, Fodor P, Foley J, Ford C, Fox E, Fox R, Forester M, Freedman S, Garmany G, Gazda S, Giang D, Glaun B, Gold S, Gottesman M, Gudesblatt M, Herbert J, Herskowitz A, Honeycutt W, Huddlestone J, Hull R, Hunter S, Hutton G, Jacobs D, Janicki M, Khatri B, Kinkel R, Kita M, Krolczyk S, Krupp L, LaGanke C, Levin M, Licht J, Luzzio C, Lynch S, Mattson D, Mikol D, Miller T, Minagar A, Mitchell G, Moses H, Negroski D, Newman S, Pardo G, Patel M, Perel A, Phillips J, Picone M, Rammohan K, Rao T, Rinker J, Sadiq S, Schaeffer J, Sheremata W, Shin R, Shubin R, Silverman S, Smith R, Stein L, Stein M, Steiner D, Steingo B, Sullivan H, Sunter W, Vaishnav A, Vasquez A, Voci J, Warach J, Weinstock-Guttman B, Williams M, Wray S. Effects of delayed-release dimethyl fumarate on MRI measures in the phase 3 CONFIRM study. Neurology 2015, 84: 1145-1152. PMID: 25681448, PMCID: PMC4371413, DOI: 10.1212/wnl.0000000000001360.Peer-Reviewed Original Research
Clinical Care
Overview
Ausim Azizi, MD, PhD, is the clinical chief of neurodegenerative disorders and specializes in treating patients with cognitive and memory problems.
“More than 20 percent of the U.S. population is over age 65 and given that cognitive and memory disorders are more common in older adults, it’s an important public health issue,” Dr. Azizi says. “Memory and cognition are at the core of one’s personality and there is a stigma and fear attached to dementia. People worry about genetics and transmission, and patients worry about becoming a shell of themselves.”
Dr. Azizi says he focuses on family members and caregivers as well. “Dementia doesn’t just affect the patient. In fact, when a patient stops remembering things, they perhaps suffer the least,” he says. “So, it becomes more about working with family and caregivers to keep patients comfortable and independent and to support the care givers.”
The most rewarding part of his job, he says, is educating patients and families. “I enjoy teaching them about their conditions and how to maintain their independence and give them power to live with their disease and treat the disease as best as we can,” he says.
Dr. Azizi’s research is focused on taking the functional, social, and biological aspects of dementia and determining how to deliver the best quality care to patients, which will also help caregivers, families, and the community.
Clinical Specialties
Neurology; Memory Disorders & Cognitive Neurology
Fact Sheets
Alzheimer's Disease
Learn More on Yale MedicineDementia
Learn More on Yale Medicine
Board Certifications
Neurology
- Certification Organization
- United Council for Neurologic Subspecialties
- Original Certification Date
- 2017
Neurocritical Care
- Certification Organization
- United Council for Neurologic Subspecialties
- Original Certification Date
- 2010
Yale Medicine News
News
News
- July 25, 2026Source: The Miami Herald Online (with Sayed Azizi, MD, PhD)
Alzheimer's blood tests qualifications: Here's how doctors decide if you're an eligible candidate
- December 03, 2025Source: HuffPost
These Are The Ages When Your Brain Has Its Biggest Transformations
- July 21, 2025Source: Hartford Courant
A CT doctor sees new hope for Alzheimer's disease patients and families. He wants you to know why.
- December 19, 2024Source: BuzzFeed
This Simple Activity Could Boost Your Brain Function And Lower Your Risk Of Dementia, And You Can Literally Start Doing It Right Now
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Appointment Number
Mailing Address
Yale Medicine
333 Cedar Street
New Haven, CT 06510
United States
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