Santiago Callegari, MD
Hospital ResidentCards
About
Research
Publications
2026
Evolving dynamic needs for patient-reported outcomes assessment in individuals with an abdominal aortic aneurysm (AAA): A systematic review.
Smolderen K, Tapia C, Dennis B, Callegari S, Dahl M, Lindholt J, Van Herzeele I, Romain G, Mena-Hurtado C. Evolving dynamic needs for patient-reported outcomes assessment in individuals with an abdominal aortic aneurysm (AAA): A systematic review. Vascular Medicine 2026, 1358863x261417234. PMID: 41854119, DOI: 10.1177/1358863x261417234.Peer-Reviewed Original ResearchPatient-reported outcomesMental health assessmentAbdominal aortic aneurysmHealth assessmentPatient-centered dimensionsPatient-centered carePatient-reported outcome assessmentsHealth status instrumentsPatient-centered experiencePatient-reported outcome evaluationPatient-reported outcome studyMeasures of social connectionEmotional Well-BeingBiopsychosocial profilePhysical symptomsOutcome assessmentSystematic reviewResponse burdenDisease burdenTreatment satisfactionAbdominal aortic aneurysm (AAAClinical complexityAdaptive testingWell-beingSingle itemsLung and Venous Excess Ultrasound Correlation With Intracardiac Pressures Before and After Decongestion in Critically Ill Patients With Acute Decompensated Heart Failure
Jimenez J, Narula S, Callegari S, Argaiz E, Chen E, Arroyo R, Miao J, Feldman Z, Ali T, Donroe J, Miller P. Lung and Venous Excess Ultrasound Correlation With Intracardiac Pressures Before and After Decongestion in Critically Ill Patients With Acute Decompensated Heart Failure. Critical Care Explorations 2026, 8: e1385. PMID: 41805782, PMCID: PMC12978832, DOI: 10.1097/cce.0000000000001385.Peer-Reviewed Original ResearchConceptsPulmonary artery occlusion pressureAcute decompensated heart failureDecompensated heart failureRight atrial pressureCritically ill patientsRenal venous stasis indexHeart failurePulsatility fractionIll patientsIntracardiac pressuresLung ultrasoundHemodynamic monitoringPulmonary artery catheter placementIntracardiac filling pressuresCardiac filling pressuresLung ultrasound scoreMultiple organ dysfunctionArtery catheter placementPilot study of adultsArtery occlusion pressureCardiac intensive carePaired measurementsUltrasound correlationStudy of adultsCatheter placementRole of Depression and Anxiety in Peripheral Artery Disease: Correlates, Outcomes, and Considerations for Treatment
Callegari S, Mubarak E, Romain G, Golledge J, Mena-Hurtado C, Smolderen K. Role of Depression and Anxiety in Peripheral Artery Disease: Correlates, Outcomes, and Considerations for Treatment. Arteriosclerosis Thrombosis And Vascular Biology 2026, 46: e322135. PMID: 41711026, PMCID: PMC13007888, DOI: 10.1161/atvbaha.125.322135.Peer-Reviewed Original ResearchConceptsPeripheral arterial diseaseArtery diseasePeripheral artery disease managementAssociated with high mortalityCardiovascular disease managementMetabolic risk factorsAnxiety assessmentAnxietyLong-term outcomesProgression of peripheral arterial diseaseDepressionExercise therapyHealth statusMajor amputationBehavioral mechanismsTreatment outcomesTeam-basedSurgical approachBiopsychosocial circumstancesTreatment planningDisease managementHigh riskRisk factorsVessel patencyWorse disease
2025
Behavioral and Mental Health Considerations for Patients Experiencing Vasculogenic Claudication
Callegari S, Mena-Hurtado C, Smolderen K. Behavioral and Mental Health Considerations for Patients Experiencing Vasculogenic Claudication. 2025, 145-162. DOI: 10.1007/978-3-032-02460-2_11.Peer-Reviewed Original ResearchPeripheral arterial diseaseMental health considerationsPatient experienceImpact of peripheral arterial diseaseHealth considerationsMental health problemsHolistic careHealth problemsPsychological factorsPsychological functioningClaudicationTreatment successStage of diseaseMultidimensional approachArtery diseaseOutcomesPatientsCareVasculogenic claudicationInterventionRisk assessmentPeriprocedural outcomes of embolic protection device use in carotid artery stenting
Callegari S, Romain G, Balasquide Odeh O, Tapia C, Pinto D, Rahman M, Vashist A, Smolderen K, Mena-Hurtado C. Periprocedural outcomes of embolic protection device use in carotid artery stenting. Journal Of Vascular Surgery 2025, 83: 738-746.e3. PMID: 41077289, DOI: 10.1016/j.jvs.2025.10.004.Peer-Reviewed Original ResearchCarotid artery stentingEmbolic protection devicesIn-Hospital MortalityNational quality improvement effortsPeriprocedural outcomesAssociated with higher oddsCumulative incidenceQuality improvement effortsArtery stentingCox proportional hazards regressionAssociated with higher in-hospitalAssociated with lower mortalityEPD groupHigher in-hospitalVascular Quality Initiative registryRisk of deathCarotid artery stenosisHigher oddsManagement of carotid artery stenosisMortality outcomesImprovement effortsTranscarotid artery revascularizationPropensity score matchingHazards regressionDevice useApplying a Random Forest Approach in Predicting Health Status in Patients with Carotid Artery Stenosis 30 Days Post Stenting
Qureshi O, Mena‐Hurtado C, Romain G, Cleman J, Callegari S, Smolderen K. Applying a Random Forest Approach in Predicting Health Status in Patients with Carotid Artery Stenosis 30 Days Post Stenting. Stroke Vascular And Interventional Neurology 2025, 5: e001938. PMID: 41608717, PMCID: PMC12697605, DOI: 10.1161/svin.125.001938.Peer-Reviewed Original ResearchHealth statusMultivariate linear regression modelComponent summaryStroke Scale scoreLinear regression modelsScale scoreHealth status outcomesMental component summaryPhysical component summaryHealth status scoresShort Form SurveyHealth status benefitsRegression modelsDecision-making discussionsHigh riskHistory of strokeNational Institutes of Health Stroke Scale scoreNational InstituteCarotid artery stentingProtection of patientsVisual analogue scaleHealth outcomesStatus outcomesNon-Hispanic/LatinoObstructive pulmonary diseasePulmonary Artery Catheter Timing and Outcomes for Patients With Cardiogenic Shock
Safiriyu I, Callegari S, Gastanadui M, El Zarif T, Ali T, Jacobs M, Desai N, Gage A, Jentzer J, Elliott A, Katz J, Miller P. Pulmonary Artery Catheter Timing and Outcomes for Patients With Cardiogenic Shock. JACC Heart Failure 2025, 13: 102609. PMID: 40811933, DOI: 10.1016/j.jchf.2025.102609.Peer-Reviewed Original ResearchAssociation between depressive symptoms and health status outcomes in patients with symptomatic peripheral artery disease
Jacque F, Mubarak E, Romain G, Poghni P, Cleman J, Mares A, Callegari S, Scierka L, Mena-Hurtado C, Smolderen K. Association between depressive symptoms and health status outcomes in patients with symptomatic peripheral artery disease. Journal Of Psychosomatic Research 2025, 196: 112339. PMID: 40753799, PMCID: PMC12455933, DOI: 10.1016/j.jpsychores.2025.112339.Peer-Reviewed Original ResearchConceptsPeripheral Artery QuestionnaireHealth status outcomesPeripheral artery questionnaire scoresPeripheral arterial diseaseDepressive symptomsHealth statusStatus outcomesIntegration of depression managementPeripheral artery disease careDepression severityBaseline health statusPatient Health QuestionnaireBaseline depressive symptomsSevere depressive symptomsArtery diseaseAssociated with adverse clinical outcomesSymptomatic peripheral arterial diseaseAdverse clinical outcomesDepression managementSpecialty careHealth QuestionnairePropensity-matched cohortPHQ-8Summary scoreClinical outcomesComparative Study of Bone-Avid SPECT Tracers: In Search of a Diagnostic Target of Cardiac Amyloidosis
Zohora F, Lin A, Jang S, Vermillion B, Burns R, Callegari S, DePino A, Liu C, Miller E, Thorn S, Sinusas A. Comparative Study of Bone-Avid SPECT Tracers: In Search of a Diagnostic Target of Cardiac Amyloidosis. Journal Of Nuclear Cardiology 2025, 50: 102377. DOI: 10.1016/j.nuclcard.2025.102377.Peer-Reviewed Original ResearchDiabetes status and long-term mortality and major amputation outcomes following revascularization in chronic limb-threatening ischemia
Callegari S, Romain G, Aggarwal A, Cleman J, Smolderen K, Mena-Hurtado C. Diabetes status and long-term mortality and major amputation outcomes following revascularization in chronic limb-threatening ischemia. Journal Of Vascular Surgery 2025, 82: 1401-1411.e5. PMID: 40348290, DOI: 10.1016/j.jvs.2025.04.065.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaLower-extremity bypassSub-hazard ratiosPeripheral vascular interventionsDM statusRisk of deathLimb-threatening ischemiaTeam-based careShared decision-makingCumulative incidenceDiabetes mellitusMedicare claims dataCumulative incidence of mortalityAll-Cause MortalityType of revascularizationAmputation outcomesCare offerFine-Gray modelClaims dataCumulative incidence of deathLong-term mortalityMortality riskCox regression modelsHazard ratioDiabetes status
Academic Achievements & Community Involvement
News
News
- April 13, 2026
Internal Medicine 2027 - 2028 Chief Resident Announcement
- November 05, 2024
Yale Researchers at American Heart Association Scientific Session 2024
- September 10, 2024
Microvasculature Imaging Shows Promise for Peripheral Artery Disease Management
- August 14, 2024
Peripheral Artery Disease Treatment: Changing the Status Quo