Priscilla Cristina Cruz, MD, MPH
Hospital ResidentCards
About
Research
Publications
2021
Seminal fluid proteins induce transcriptome changes in the Aedes aegypti female lower reproductive tract
Amaro I, Ahmed-Braimah Y, League G, Pitcher S, Avila F, Cruz P, Harrington L, Wolfner M. Seminal fluid proteins induce transcriptome changes in the Aedes aegypti female lower reproductive tract. BMC Genomics 2021, 22: 896. PMID: 34906087, PMCID: PMC8672594, DOI: 10.1186/s12864-021-08201-0.Peer-Reviewed Original ResearchConceptsSeminal fluid proteinsMale accessory glandsFemale lower reproductive tractTranscript level changesAccessory glandsTranscriptomic changesLower reproductive tractPost-mating responsesArbovirus vectors Aedes aegyptiReproductive tractDifferentially-regulated genesGene expression responsesFluid proteinsSeminal proteinsTranscriptional controlSmall molecule bindingExpression responsesGenesMolecular processesSpermathecaProteinVector Aedes aegyptiSeminal vesiclesNatural matingConclusionsOur resultsThe impact of mating and sugar feeding on blood-feeding physiology and behavior in the arbovirus vector mosquito Aedes aegypti
League G, Degner E, Pitcher S, Hafezi Y, Tennant E, Cruz P, Krishnan R, Castillo S, Alfonso-Parra C, Avila F, Wolfner M, Harrington L. The impact of mating and sugar feeding on blood-feeding physiology and behavior in the arbovirus vector mosquito Aedes aegypti. PLOS Neglected Tropical Diseases 2021, 15: e0009815. PMID: 34591860, PMCID: PMC8509887, DOI: 10.1371/journal.pntd.0009815.Peer-Reviewed Original ResearchConceptsMale accessory gland extractsBlood feedingInitial blood mealPost-mating changesSugar feedingAccessory gland extractsImpact of matingVector mosquito Aedes aegyptiMosquito blood feedingMosquito life historyMosquito Aedes aegyptiMosquito biologyNear hostsBlood mealVectors of virusesFemale behaviorMatingLife historyMating effectBiological crosstalkMosquito ecologyVertebrate hostsFeeding impactVectorial capacityBlood intake