Olga Grechukhina, MD
Cards
About
Research
Publications
2024
Reporting Perinatal Substance Use to Child Protective Services: Obstetric Provider Perspectives on the Impact on Care
Kaufman J, Yonkers K, Maltz C, Friedhoff C, Tobon A, Mele A, Tessier-Kay M, Grechukhina O, Lipkind H, Byatt N, Forray A. Reporting Perinatal Substance Use to Child Protective Services: Obstetric Provider Perspectives on the Impact on Care. Journal Of Women's Health 2024 PMID: 38770764, DOI: 10.1089/jwh.2023.0822.Peer-Reviewed Original ResearchOpioid use disorderProvider perspectiveKey informant interviewsCPS involvementNurse practitionersAffect careObstetric patientsCareInformant interviewsPostpartum patientsReporting requirementsCPS reportsProvidersContent analysisPerinatal individualsUse disorderSocial workersThematic areasPatientsFearNursesMandated reportersObstetriciansPostpartumStaffAssociation Between Intrapartum Nitrous Oxide for Labor Analgesia and Short-Term Neonatal Outcomes
Starosta A, Lundsberg L, Culhane J, Partridge C, Grechukhina O, Son M. Association Between Intrapartum Nitrous Oxide for Labor Analgesia and Short-Term Neonatal Outcomes. Obstetrics And Gynecology 2024, 143: 677-682. PMID: 38484306, DOI: 10.1097/aog.0000000000005554.Peer-Reviewed Original ResearchShort-term neonatal outcomesNeonatal intensive care unitNo analgesiaNeonatal outcomesApgar scoreLabor analgesiaComposite outcomeAdverse short-term neonatal outcomesNeonatal intensive care unit admissionSecondary outcomesSingle-center retrospective cohortRetrospective cohort study of individualsCohort study of individualsLow-risk patientsRetrospective cohort studyIntensive care unitElectronic medical recordsNitrous oxide useAnalgesia typeIntrapartum cesareanSingleton gestationsNICU admissionNitrous oxide exposureIntrapartum analgesiaNeonatal hyperbilirubinemia
2023
Severe Maternal Morbidity Review and Preventability Assessment in a Large Academic Center
Grechukhina O, Lipkind H, Lundsberg L, Merriam A, Raab C, Leon-Martinez D, Campbell K. Severe Maternal Morbidity Review and Preventability Assessment in a Large Academic Center. Obstetrics And Gynecology 2023, 141: 857-860. PMID: 36897178, DOI: 10.1097/aog.0000000000005116.Peer-Reviewed Original ResearchConceptsSevere maternal morbiditySystem-level factorsYale-New Haven HospitalRetrospective cohort studyHealth careDetailed case reviewLarge academic centerSMM ratesMaternal morbidityCohort studyPreventability assessmentPreventable causeSMM casesMorbidity reviewAmerican CollegeAcademic centersConsensus criteriaCase reviewPractice changeCareCauseMorbidityHemorrhagePreventabilityReview
2022
Seizing the Window of Opportunity Within 1 Year Postpartum: Early Cardiovascular Screening
Ackerman‐Banks C, Grechukhina O, Spatz E, Lundsberg L, Chou J, Smith G, Greenberg VR, Reddy UM, Xu X, O’Bryan J, Smith S, Perley L, Lipkind HS. Seizing the Window of Opportunity Within 1 Year Postpartum: Early Cardiovascular Screening. Journal Of The American Heart Association 2022, 11: e024443. PMID: 35411781, PMCID: PMC9238464, DOI: 10.1161/jaha.121.024443.Peer-Reviewed Original ResearchConceptsHDP groupBody mass indexChronic hypertensionMonths postpartumHypertension 6Metabolic syndromeMass indexYear postpartumFamily historyMedical conditionsNew diagnosisHigh low-density lipoprotein cholesterolLow-density lipoprotein cholesterolEffective primary prevention strategiesPreexisting medical conditionsProspective cohort studyCVD risk scoreUnderlying medical conditionsCardiovascular disease riskMultidisciplinary care modelMultivariable logistic regressionDevelopment of CVDFirst year postpartumPrimary prevention strategiesHypertensive disordersMaternal-fetal medicine fellows’ perception and comfort with obstetrical ultrasound and prenatal diagnosis
Holliman K, Pluym ID, Grechukhina O, Blumenfeld YJ, Platt LD, Copel JA, Han CS. Maternal-fetal medicine fellows’ perception and comfort with obstetrical ultrasound and prenatal diagnosis. American Journal Of Obstetrics & Gynecology MFM 2022, 4: 100601. PMID: 35217235, DOI: 10.1016/j.ajogmf.2022.100601.Peer-Reviewed Original Research
2021
Maternal outcomes and risk factors for COVID-19 severity among pregnant women
Vouga M, Favre G, Martinez-Perez O, Pomar L, Acebal LF, Abascal-Saiz A, Hernandez MRV, Hcini N, Lambert V, Carles G, Sichitiu J, Salomon L, Stirnemann J, Ville Y, de Tejada BM, Goncé A, Hawkins-Villarreal A, Castillo K, Solsona EG, Trigo L, Cleary B, Geary M, Bartels H, Al-Kharouf F, Malone F, Higgins M, Keating N, Knowles S, Poncelet C, Ribeiro-do-Valle CC, Surita F, Dantas-Silva A, Borrelli C, Luz AG, Fuenzalida J, Carvajal J, Canales MG, Hernandez O, Grechukhina O, Ko AI, Reddy U, Figueiredo R, Moucho M, Pinto PV, De Luca C, De Santis M, de Campos DA, Martins I, Garabedian C, Subtil D, Bohrer B, Da Rocha Oppermann ML, Wender MCO, Schuler-Faccini L, Sanseverino MTV, Giugliani C, Friedrich L, Scherer MH, Mottet N, Ducarme G, Pelerin H, Moreau C, Breton B, Quibel T, Rozenberg P, Giannoni E, Granado C, Monod C, Mueller D, Hoesli I, Bassler D, Heldstab S, Kölble NO, Sentilhes L, Charvet M, Deprest J, Richter J, Van der Veeken L, Eggel-Hort B, Plantefeve G, Derouich M, Calvache AJN, Lopez-Giron MC, Burgos-Luna JM, Escobar-Vidarte MF, Hecher K, Tallarek AC, Hadar E, Haratz KK, Amikam U, Malinger G, Maymon R, Yogev Y, Schäffer L, Toussaint A, Rossier MC, De Sa RAM, Grawe C, Aebi-Popp K, Radan AP, Raio L, Surbek D, Böckenhoff P, Strizek B, Kaufmann M, Bloch A, Boulvain M, Johann S, Heldstab SA, Bernasconi MT, Grant G, Feki A, Brochut AM, Giral M, Sedille L, Papadia A, Brugger RC, Weber B, Fischer T, Kahlert C, Saines KN, Cambou M, Kanellos P, Chen X, Yin M, Haessig A, Ackermann S, Baud D, Panchaud A. Maternal outcomes and risk factors for COVID-19 severity among pregnant women. Scientific Reports 2021, 11: 13898. PMID: 34230507, PMCID: PMC8260739, DOI: 10.1038/s41598-021-92357-y.Peer-Reviewed Original ResearchConceptsSevere maternal outcomesPregnant womenRisk factorsMaternal outcomesPulmonary comorbiditiesHypertensive disordersNeonatal outcomesSevere complicationsHigh riskSevere acute respiratory syndrome coronavirus 2Severe coronavirus disease-19Severe COVID-19 diseaseAcute respiratory syndrome coronavirus 2Neonatal intensive care unitSARS-CoV-2 infectionRespiratory syndrome coronavirus 2Immediate neonatal outcomeIntensive care unitSyndrome coronavirus 2COVID-19 severityCase-control studyCoronavirus disease-19SARS-CoV-2COVID-19 diseaseMaternal disease352 Regional heterogeneity in ultrasound and procedural training in maternal-fetal medicine fellowship: a cross-sectional survey
Holliman K, Pluym I, Grechukhina O, Blumenfeld Y, Platt L, Copel J, Han C. 352 Regional heterogeneity in ultrasound and procedural training in maternal-fetal medicine fellowship: a cross-sectional survey. American Journal Of Obstetrics And Gynecology 2021, 224: s230-s231. DOI: 10.1016/j.ajog.2020.12.373.Peer-Reviewed Original Research
2020
Coronavirus disease 2019 pregnancy outcomes in a racially and ethnically diverse population
Grechukhina O, Greenberg V, Lundsberg LS, Deshmukh U, Cate J, Lipkind HS, Campbell KH, Pettker CM, Kohari KS, Reddy UM. Coronavirus disease 2019 pregnancy outcomes in a racially and ethnically diverse population. American Journal Of Obstetrics & Gynecology MFM 2020, 2: 100246. PMID: 33047100, PMCID: PMC7539936, DOI: 10.1016/j.ajogmf.2020.100246.Peer-Reviewed Original ResearchMeSH KeywordsAdultCommunicable Disease ControlComorbidityCOVID-19COVID-19 TestingEthnicityFemaleHealth Status DisparitiesHospitalizationHumansInfant, NewbornNew YorkObstetrics and Gynecology Department, HospitalPregnancyPregnancy Complications, InfectiousPregnancy OutcomePremature BirthRisk AssessmentRisk FactorsSARS-CoV-2ConceptsCoronavirus disease 2019Severe acute respiratory syndrome coronavirusAcute respiratory syndrome coronavirusSevere diseaseDisease 2019Pregnancy outcomesPositive test resultsClinical coursePostpartum womenRisk factorsHispanic ethnicityHispanic womenSevere acute respiratory syndrome coronavirus 2Coronavirus disease 2019 courseAcute respiratory syndrome coronavirus 2Severe coronavirus disease 2019Respiratory syndrome coronavirus 2Severe acute respiratory syndrome 2Effect of comorbidityWorse clinical courseC-reactive proteinSyndrome coronavirus 2Hypertensive disordersMedical comorbiditiesObese womenVertical transmission of coronavirus disease 2019: a systematic review and meta-analysis
Kotlyar A, Grechukhina O, Chen A, Popkhadze S, Grimshaw A, Tal O, Taylor HS, Tal R. Vertical transmission of coronavirus disease 2019: a systematic review and meta-analysis. American Journal Of Obstetrics And Gynecology 2020, 224: 35-53.e3. PMID: 32739398, PMCID: PMC7392880, DOI: 10.1016/j.ajog.2020.07.049.Peer-Reviewed Original ResearchConceptsSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Syndrome coronavirus 2Coronavirus disease 2019Case series studyPooled proportionCoronavirus 2Disease 2019Vertical transmissionSystematic reviewNasopharyngeal swabsRNA testNeonatal serologySevere acute respiratory syndrome coronavirus 2 positivitySeries studyCoronavirus disease 2019 (COVID-19) infectionCoronavirus disease 2019 (COVID-19) diagnosisTesting of neonatesDisease 2019 infectionHours of birthNewcastle-Ottawa ScaleViral RNA testingNeonatal cord bloodRate of infection1063: Endometrial and myometrial cell CXCL12 expression in response to mechanical injury: implications for placenta accreta.
Grechukhina O, Popkhadze S, Taylor H. 1063: Endometrial and myometrial cell CXCL12 expression in response to mechanical injury: implications for placenta accreta. American Journal Of Obstetrics And Gynecology 2020, 222: s657. DOI: 10.1016/j.ajog.2019.11.1077.Peer-Reviewed Original Research
Clinical Trials
Current Trials
Aspirin to Prevent Preeclampsia in Women With Elevated Blood Pressure and Stage 1 Hypertension (ASPPIRE)
HIC ID2000028023RolePrincipal InvestigatorPrimary Completion Date07/31/2022Recruiting ParticipantsGenderFemaleAge18+ yearsChronic Hypertension and Pregnancy (CHAP) Project (CHAP)
HIC ID2000024291RoleSub InvestigatorPrimary Completion Date12/31/2020Recruiting ParticipantsGenderFemaleAge12+ years
Academic Achievements and Community Involvement
Clinical Care
Overview
Olga Grechukhina, MD, is an obstetrician-gynecologist who specializes in maternal-fetal medicine, or high-risk pregnancies.
Growing up, Dr. Grechukhina says she was always interested in science. “I love medicine because the human body is like a huge puzzle. So many things need to work out and they usually do,” she says. “I was equally fascinated with developing embryos. It’s such a complex process.”
Dr. Grechukhina says she was drawn to maternal-fetal medicine because it’s a mix of everything related to obstetrics, in addition to critical care and radiology. “You are taking care of two patients instead of one. I love that multi-faceted, yet granular, aspect,” she says.
Being with her patients and sharing in their joy or supporting them through difficult times is an honor, she says. “It’s an amazing moment when a woman who has gone through a very complicated pregnancy delivers her baby,” she says.
Dr. Grechukhina’s interests includes severe maternal morbidity. “It’s near miss-events—when a woman gets close to dying—that lead us to have a better understanding of what we, as providers, can do better to prevent such cases from occurring,” she explains.
Clinical Specialties
Maternal-Fetal Medicine
Fact Sheets
Fetal Therapy
Learn More on Yale MedicineHigh-Risk Pregnancy
Learn More on Yale MedicineHypertension (High Blood Pressure) During Pregnancy
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Obstetrics, Gynecology & Reproductive Sciences
333 Cedar Street, PO Box 208063
New Haven, CT 06510
United States
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