About
Biography
Education & Training
- MS
- University of Pittsburgh, Clinical Research (2014)
- MBBS
- Christian Medical College, Vellore (2007)
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Nitya Bakshi's published research.
Publications Timeline
A big-picture view of Nitya Bakshi's research output by year.
Lakshmanan Krishnamurti, MD
Inci Yildirim, MD, PhD, MSc
65Publications
768Citations
Publications
2024
Impact of arginine therapy on kyotorphin in children with sickle cell disease and vaso-occlusive pain
Korman R, Hatabah D, Brown L, Harris F, Wilkinson H, Rees C, Bakshi N, Archer D, Dampier C, Morris C. Impact of arginine therapy on kyotorphin in children with sickle cell disease and vaso-occlusive pain. Blood Advances 2024, 8: 3267-3271. PMID: 38527291, PMCID: PMC11226964, DOI: 10.1182/bloodadvances.2023012209.Peer-Reviewed Original ResearchAltmetricCobalamin Deficiency in Children with Sickle Cell Disease
Hatabah D, Kreiger R, Brown L, Harris F, Korman R, Benedit L, Rees C, Bakshi N, Dampier C, Morris C. Cobalamin Deficiency in Children with Sickle Cell Disease. 2024, 1 DOI: 10.1093/jscdis/yoae002.011.Peer-Reviewed Original ResearchAltmetricConceptsPrevalence of B12 deficiencyDiagnosis of B12 deficiencyPlasma methylmalonic acidSickle cell diseaseB12 deficiencyMethylmalonic acidCobalamin deficiencyB12 supplementationEffects of B12 supplementationSecondary analysis of samplesTreatment of acute painCell diseaseMarker of B12 deficiencyElevated plasma methylmalonic acidEmergency departmentNon-deficient groupPhase II randomized controlled trialIrreversible neurological impairmentIncreased nutritional requirementsStudent's t-testPediatric emergency departmentRandomized controlled trialsIV opioidsPearson chi-squareRenal impairmentHigh-impact chronic pain in sickle cell disease: insights from the Pain in Sickle Cell Epidemiology Study (PiSCES).
Jagtiani A, Chou E, Gillespie S, Liu K, Krishnamurti L, McClish D, Smith W, Bakshi N. High-impact chronic pain in sickle cell disease: insights from the Pain in Sickle Cell Epidemiology Study (PiSCES). Pain 2024 PMID: 38787626, DOI: 10.1097/j.pain.0000000000003262.Peer-Reviewed Original ResearchAltmetricConceptsHigh-impact chronic painSickle Cell Epidemiology StudyChronic painProportion of daysUS National Pain StrategySickle cell diseaseNational Pain StrategySelf-care activitiesEpidemiological studiesHigher levels of stressMean pain intensityCohort of individualsPain interferenceLevels of stressPhysical functionHealth outcomesHealthcare utilizationPhysical healthPain strategiesPain burdenPain intensityPain diaryCell diseaseDiary daysAffected subgroupsMediators and Moderators of Cognitive-Behavioral Digital Health Intervention for Youth with Sickle Cell Disease Pain
Srinakarin K, Sanpoori S, Lalloo C, Zhou C, Dampier C, Zempsky W, Badawy S, Bakshi N, Ko Y, Nishat F, Stinson J, Palermo T. Mediators and Moderators of Cognitive-Behavioral Digital Health Intervention for Youth with Sickle Cell Disease Pain. Journal Of Pain 2024, 25: 56. DOI: 10.1016/j.jpain.2024.01.257.Peer-Reviewed Original ResearchConceptsCognitive-behavioral therapyPatient activationSocial supportEffectiveness of cognitive-behavioral therapySymptoms of sickle cell diseaseSelf-efficacyDigital health interventionsSickle cell disease painPain intensity outcomesChronic SCD painParental psychological distressAdolescents' self-efficacySecondary data analysisPre-treatment variablesActivity interventionsAdolescent variablesHealth interventionsIntervention effectsPsychological distressEffect modificationParental distressEducation controlIntensity outcomesPain intensityControl arm
2023
A cognitive–behavioral digital health intervention for sickle cell disease pain in adolescents: a randomized, controlled, multicenter trial
Palermo T, Lalloo C, Zhou C, Dampier C, Zempsky W, Badawy S, Bakshi N, Ko Y, Nishat F, Stinson J. A cognitive–behavioral digital health intervention for sickle cell disease pain in adolescents: a randomized, controlled, multicenter trial. Pain 2023, 165: 164-176. PMID: 37733479, PMCID: PMC10723646, DOI: 10.1097/j.pain.0000000000003009.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsSickle cell diseaseEducation controlSickle Cell Disease PainEvidence-based cognitive behavioral therapySickle cell painAverage pain intensitySignificant healthcare costsCognitive behavioral therapy programCognitive behavioral therapyDigital health interventionsPain daysSCD clinicSecondary outcomesCommon complicationDisease painMulticenter trialPain intensityPain interferenceChronic painPain interventionsEffective implementation strategiesGlobal ImpressionCell diseasePsychosocial distressPainPatient-reported outcomes in children with sickle cell disease at presentation for an acute pain episode
Bakshi N, Liu Z, Gillespie S, Keesari R, Leake D, Khemani K, Kumari P, Rees C, Dampier C, Morris C. Patient-reported outcomes in children with sickle cell disease at presentation for an acute pain episode. Blood Advances 2023, 7: 5103-5107. PMID: 36322873, PMCID: PMC10477437, DOI: 10.1182/bloodadvances.2021006794.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsSickle Cell Disease Treatment with Arginine Therapy (STArT): study protocol for a phase 3 randomized controlled trial
Rees C, Brousseau D, Cohen D, Villella A, Dampier C, Brown K, Campbell A, Chumpitazi C, Airewele G, Chang T, Denton C, Ellison A, Thompson A, Ahmad F, Bakshi N, Coleman K, Leibovich S, Leake D, Hatabah D, Wilkinson H, Robinson M, Casper T, Vichinsky E, Morris C. Sickle Cell Disease Treatment with Arginine Therapy (STArT): study protocol for a phase 3 randomized controlled trial. Trials 2023, 24: 538. PMID: 37587492, PMCID: PMC10433602, DOI: 10.1186/s13063-023-07538-z.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPediatric Emergency Care Applied Research NetworkSickle cell disease treatmentVaso-occlusive episodesSickle cell diseaseSTART trialArginine therapyIntravenous arginineLoading doseNormal saline three timesYoung adultsBlood Institute guidelinesParental opioid usePlacebo loading doseSubstantial illness burdenDisease-modifying therapiesPatient-reported outcomesDisease treatmentPhase 3Emergency medicine providersSaline three timesMulticenter research networkResearch NetworkIntravenous opioidsLast doseStudy drugSex and frequency of pain episodes are associated with acute pain trajectories in adolescents with sickle cell disease
Astles R, Liu Z, Gillespie S, Lai K, Maillis A, Morris C, Lane P, Krishnamurti L, Bakshi N. Sex and frequency of pain episodes are associated with acute pain trajectories in adolescents with sickle cell disease. PAIN Reports 2023, 8: e1084. PMID: 37559677, PMCID: PMC10409410, DOI: 10.1097/pr9.0000000000001084.Peer-Reviewed Original ResearchCitationsAltmetricConceptsHigher health care utilizationHealth care utilizationSickle cell diseaseAcute pain trajectoriesPain intensity scoresEmergency departmentPain trajectoriesPain episodesCell diseaseHigher mean pain intensity scoreIntensity scoresMean pain intensity scoreAcute pain episodesFrequency of painAdolescent female patientsFuture prospective studiesElectronic health recordsIntranasal opioidsPain frequencyAcute painPain intensityRetrospective reviewCare utilizationFemale patientsProspective studyParental perspective on the risk of infertility and fertility preservation options for children and adolescents with sickle cell disease considering hematopoietic stem cell transplantation
Sinha C, Meacham L, Bakshi N, Ross D, Krishnamurti L. Parental perspective on the risk of infertility and fertility preservation options for children and adolescents with sickle cell disease considering hematopoietic stem cell transplantation. Pediatric Blood & Cancer 2023, 70: e30276. PMID: 37051746, PMCID: PMC10544372, DOI: 10.1002/pbc.30276.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsHematopoietic stem cell transplantationRisk of infertilitySickle cell diseaseStem cell transplantationFertility preservationCell transplantationCell diseaseMajor long-term complicationPrimary caregiversIdentical related donorsDisease-free survivalFertility preservation optionsFertility preservation proceduresLong-term complicationsHuman leukocyte antigenConditioning regimenHost diseaseRelated donorsLeukocyte antigenPreservation optionsHCT physiciansSurvival rateAvailable HLAEleven participantsInfertilityIntranasal fentanyl and discharge from the emergency department among children with sickle cell disease and vaso‐occlusive pain: A multicenter pediatric emergency medicine perspective
Rees C, Brousseau D, Ahmad F, Bennett J, Bhatt S, Bogie A, Brown K, Casper T, Chapman L, Chumpitazi C, Cohen D, Dampier C, Ellison A, Grasemann H, Hatabah D, Hickey R, Hsu L, Bakshi N, Leibovich S, Patil P, Powell E, Richards R, Sarnaik S, Weiner D, Morris C, Group and PECARN T. Intranasal fentanyl and discharge from the emergency department among children with sickle cell disease and vaso‐occlusive pain: A multicenter pediatric emergency medicine perspective. American Journal Of Hematology 2023, 98: 620-627. PMID: 36606705, PMCID: PMC10023395, DOI: 10.1002/ajh.26837.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsVaso-occlusive pain episodesSickle cell diseaseIntranasal fentanylEmergency departmentTreatment of childrenMulticenter studyCell diseaseAcademic pediatric emergency departmentOutcome of dischargeVaso-occlusive painAcute care settingPediatric emergency departmentSickling of erythrocytesCross-sectional studyEmergency medicine perspectivePain episodesParenteral analgesicsIntravenous accessMedian ageAdjusted oddsMultivariable associationsFentanylRapid onsetEase of deliveryLogistic regression
Clinical Care
Overview
Clinical Specialties
Pediatric Hematology & Oncology
Fact Sheets
Sickle Cell Disease
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Board Certifications
Pediatric Hematology-Oncology
- Certification Organization
- AB of Pediatrics
- Original Certification Date
- 2015
Pediatrics
- Certification Organization
- AB of Pediatrics
- Original Certification Date
- 2011
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