Murat Basar, PhD
Associate Research ScientistCards
About
Research
Publications
Featured Publications
Enhancing outcomes in IVF laboratories: navigating the human element through leadership and emotional intelligence
Basar M. Enhancing outcomes in IVF laboratories: navigating the human element through leadership and emotional intelligence. Journal Of Assisted Reproduction And Genetics 2024, 41: 2557-2567. PMID: 39225839, PMCID: PMC11535114, DOI: 10.1007/s10815-024-03239-x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsLeadership styleHuman factorsTeam dynamicsEmotional intelligenceHuman elementManagement developmentStaff well-beingToxic workplacesLeadershipEI trainingPromote emotional intelligenceSoft skillsOperational frameworkWell-beingReview contemporary literatureAcademic communityTeamTechnical expertisePersonality dynamicsContemporary literatureInterpersonal aspectsStyleWorkplaceStaff membersEmbryology with precision: effective quality control in the in vitro fertilization laboratory
Basar M, Unsal E, Ergun Y. Embryology with precision: effective quality control in the in vitro fertilization laboratory. Current Opinion In Obstetrics & Gynecology 2024, 36: 200-207. PMID: 38572581, DOI: 10.1097/gco.0000000000000945.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPreimplantation genetic testingIn vitro fertilizationIntracytoplasmic sperm injectionProportion of mature oocytesIn vitro fertilization treatmentClinical pregnancy rateClinical practiceIn vitro fertilization laboratoryEmbryo development ratesImprove IVF outcomesSuccess rateImproving clinical outcomesField of reproductive medicineSperm injectionIVF outcomesClinical outcomesIVF treatmentDiagnostic accuracySuccess rate of IVF treatmentIVF proceduresPregnancy rateGenetic testingMature oocytesReproductive medicineGenetics laboratoriesBeyond Earth’s bounds: navigating the frontiers of Assisted Reproductive Technologies (ART) in space
Chaplia O, Mathyk B, Nichols-Burns S, Basar M, Halicigil C. Beyond Earth’s bounds: navigating the frontiers of Assisted Reproductive Technologies (ART) in space. Reproductive Biology And Endocrinology 2024, 22: 123. PMID: 39394617, PMCID: PMC11468284, DOI: 10.1186/s12958-024-01290-y.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAssisted Reproductive TechnologyIn vitro embryo developmentReproductive technologyRadiation-induced damageGamete handlingClinical embryologistsReproductive endocrinologistsTemperature limitEmbryo cultureReproductive medicineLow Earth orbitEmbryo developmentDeep space travelEarth orbitSpace environmentInterplanetary speciesEarth-boundMicrofluidic devicesCryopreservationUnderstanding how space travel affects the female reproductive system to the Moon and beyond
Mathyk B, Imudia A, Quaas A, Halicigil C, Karouia F, Avci P, Nelson N, Guzeloglu-Kayisli O, Denbo M, Sanders L, Scott R, Basar M, Guevara-Cerdán A, Strug M, Monseur B, Kayisli U, Szewczyk N, Mason C, Young S, Tasoglu S, Costes S, Beheshti A. Understanding how space travel affects the female reproductive system to the Moon and beyond. Npj Women's Health 2024, 2: 20. DOI: 10.1038/s44294-024-00009-z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsHypothalamic-pituitary-gonadalFemale reproductive systemEndometrial receptivityReproductive endocrinologyHealthy live birthPreimplantation embryo developmentHypothalamic-pituitary-gonadal (HPG) axisFemale reproductive healthReproductive systemOvarian folliculogenesisCircadian rhythm changesLive birthsEmbryo implantationFemale reproductive endocrinologyEffects of space travelPregnancySpace travelReproductive healthEmbryo developmentRhythm changesAdverse effectsEndocrinologySuccessful transitionEffects of spaceflightInterplanetary speciesThe burnout: a silent saboteur in in vitro fertilization laboratories
Basar M, Duzcu T. The burnout: a silent saboteur in in vitro fertilization laboratories. Journal Of Assisted Reproduction And Genetics 2025, 42: 2497-2513. PMID: 40495039, PMCID: PMC12423373, DOI: 10.1007/s10815-025-03537-y.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAssisted Reproductive TechnologyPatient care outcomesCross-sectional surveyEmotional burnout levelEvidence-based strategiesReduced patient satisfactionConsequences of burnoutCare outcomesBurnout prevalenceStaff sustainabilityAssisted reproductive technology successIn vitro fertilization laboratorySynthesized findingsProtocol adherenceBurnout levelsOccupational stressorsPatient satisfactionExcessive workloadSystematic reviewBurnout assessmentMeta-analysesRoutine quality assurancePatient outcomesBurnoutSystem issues
2025
Impact of body weight on IVF: pathophysiology, outcomes, and clinical considerations
Sekula N, Basar M, Pal L. Impact of body weight on IVF: pathophysiology, outcomes, and clinical considerations. Current Opinion In Obstetrics & Gynecology 2025, 37: 130-140. PMID: 40172001, DOI: 10.1097/gco.0000000000001023.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsIVF outcomesExcess weightIVF cycle outcomesIVF treatment cyclesLive birth rateCycle outcomesImpact of excess weightAssociation of excess weightImpact of body weightClinical pregnancyExcess body weightBirth rateBody weightIVFAdverse implicationsUterine receptivityDetrimental implicationsWeight excessTreatment cyclesInflammatory processInsulin resistancePathogenic mechanismsClinical considerationsOutcomesDNA repair
2024
Artificial Intelligence in IVF Laboratories: Elevating Outcomes Through Precision and Efficiency
Hew Y, Kutuk D, Duzcu T, Ergun Y, Basar M. Artificial Intelligence in IVF Laboratories: Elevating Outcomes Through Precision and Efficiency. Biology 2024, 13: 988. PMID: 39765654, PMCID: PMC11727220, DOI: 10.3390/biology13120988.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsArtificial intelligenceIn vitro fertilizationPattern recognition capabilitiesHuman-machine interfaceData securityReducing human errorIn vitro fertilization laboratoryDeep learningNeural networkMachine learningAI technologyAlgorithmic biasRecognition capabilityReproductive medicineHuman errorSperm selectionEffects of AIStandard processIntelligenceIncreased accuracySensitivity fieldPersonalized treatment plansQuality assuranceOperational efficiencyLearningComparison of the Mitophagy and Apoptosis Related Gene Expressions in Waste Embryo Culture Medium of Female Infertility Types
Kütük D, Öner Ç, Başar M, Akcay B, Olcay İ, Çolak E, Selam B, Cincik M. Comparison of the Mitophagy and Apoptosis Related Gene Expressions in Waste Embryo Culture Medium of Female Infertility Types. Life 2024, 14: 1507. PMID: 39598305, PMCID: PMC11595419, DOI: 10.3390/life14111507.Peer-Reviewed Original ResearchPolycystic ovary syndromePoor ovarian reservePINK1 gene expressionGene expressionOocyte-to-embryo transitionEmbryo culture fluidApoptosis related gene expressionNormorespondersIVF centerInfertility typeCellular parametersMitochondrial DNAP53 gene expressionOvarian reserveFemale infertilityRelated gene expressionPINK1HumaninMitochondrial dysfunctionReal time PCRMfn2Embryonic development periodInfertile patientsMfn1Culture fluidEfficacy of the GnRH Agonist Trigger in Oocyte and Embryo Quality Through Mitochondrial Unfolded Protein Response
Basar M. Efficacy of the GnRH Agonist Trigger in Oocyte and Embryo Quality Through Mitochondrial Unfolded Protein Response. Experimed 2024, 14: 21-25. DOI: 10.26650/experimed.1401479.Peer-Reviewed Original ResearchMitochondrial Unfolded Protein Response Gene Clpp Is Required for Oocyte Function and Female Fertility
Ergun Y, Imamoglu A, Cozzolino M, Demirkiran C, Basar M, Garg A, Yildirim R, Seli E. Mitochondrial Unfolded Protein Response Gene Clpp Is Required for Oocyte Function and Female Fertility. International Journal Of Molecular Sciences 2024, 25: 1866. PMID: 38339144, PMCID: PMC10855406, DOI: 10.3390/ijms25031866.Peer-Reviewed Original ResearchConceptsCaseinolytic peptidase PMouse modelProtein homeostasisStress responseUnfolded protein stress responseProtein stress responseCumulus/granulosa cellsOocyte competenceOocyte functionGlobal deletionFunctional abnormalitiesGenes clpPMetabolic stress responseFemale subfertilityFemale infertilityOocyte-specificOocytesReproductive functionMtUPRMiceProtein degradationReproductive competenceFemale fertilityDeletionHomeostasis
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Yale Fertility Center
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200 West Campus Drive, Fl 2nd
Orange, CT 06477
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203.737.3988