Mario Mekhael
Clinical FellowAbout
Research
Publications
2026
Gastrointestinal Bleeding Risk Associated With Pulse Pressure in Patients With Atrial Fibrillation: A Retrospective Cohort Study (Preprint)
Abou Khalil M, El Khoury C, Moersdorf M, Massad C, El Darzi A, Menassa Y, Atasi M, Bidaoui G, Younes H, Assaf A, Mekhael M, Tsakiris E, Lim C, Noujaim C, Hassan A, Liu Y, Jia Y, Maleckar M, Montiel Quintero R, Kreidieh O, Pandey A, Feng H, Marashly Q, Marrouche N. Gastrointestinal Bleeding Risk Associated With Pulse Pressure in Patients With Atrial Fibrillation: A Retrospective Cohort Study (Preprint). Journal Of Medical Internet Research 2026 DOI: 10.2196/93347.Peer-Reviewed Original Research
2025
Atrial Arrhythmia Burden (SMURDEN) After Ablation of AF Is Associated With Improvement in Quality of Life
Bidaoui G, Feng H, Lim C, Chouman N, Assaf A, Bsoul M, Younes H, Massad C, Jia Y, Liu Y, Mekhael M, Noujaim C, Donnellan E, Kreidieh O, Pandey A, Rao S, Marrouche N. Atrial Arrhythmia Burden (SMURDEN) After Ablation of AF Is Associated With Improvement in Quality of Life. JACC Clinical Electrophysiology 2025, 11: 2421-2433. PMID: 40879592, DOI: 10.1016/j.jacep.2025.07.011.Peer-Reviewed Original ResearchEditorial: Telemedicine in cardiology
Feng H, Mekhael M, Yu D, Lim C, Miao H, Marrouche N. Editorial: Telemedicine in cardiology. Frontiers In Cardiovascular Medicine 2025, 12: 1665285. PMID: 40832140, PMCID: PMC12358368, DOI: 10.3389/fcvm.2025.1665285.Commentaries, Editorials and LettersCharacterization of arrhythmia‐induced cardiomyopathy using magnetic resonance imaging in patients with persistent atrial fibrillation and left ventricular systolic dysfunction – insights from DECAAF II
Assaf A, Feng H, Bsoul M, Bidaoui G, Younes H, Massad C, Mekhael M, Noujaim C, Kreidieh O, Rao S, Pandey A, Sommer P, Mahnkopf C, Marrouche N, Sohns C. Characterization of arrhythmia‐induced cardiomyopathy using magnetic resonance imaging in patients with persistent atrial fibrillation and left ventricular systolic dysfunction – insights from DECAAF II. European Journal Of Heart Failure 2025, 27: 1622-1632. PMID: 40356053, PMCID: PMC12502454, DOI: 10.1002/ejhf.3684.Peer-Reviewed Original ResearchImpact of left atrial myopathy and post-ablation remodeling on quality of life: a DECAAF II sub-analysis
Bidaoui G, Feng H, Chouman N, Assaf A, Lim C, Younes H, Bsoul M, Massad C, Polo F, Jia Y, Liu Y, Hassan A, Rittmeyer W, Mekhael M, Noujaim C, Pandey A, Rao S, Kreidieh O, Marrouche N, Donnellan E. Impact of left atrial myopathy and post-ablation remodeling on quality of life: a DECAAF II sub-analysis. Journal Of Interventional Cardiac Electrophysiology 2025, 68: 1225-1234. PMID: 39899141, PMCID: PMC12399685, DOI: 10.1007/s10840-025-02002-1.Peer-Reviewed Original ResearchApplication of artificial intelligence to analyze data from randomized controlled trials: An example from DECAAF II
Mekhael M, Feng H, Akoum N, Sohns C, Sommer P, Mahnkopf C, Kholmovski E, Bax J, Sanders P, McGann C, Marchlinski F, Mansour M, Hindricks G, Wilber D, Calkins H, Jais P, Younes H, Assaf A, Noujaim C, Lim C, Huang C, Pandey A, Wazni O, Marrouche N. Application of artificial intelligence to analyze data from randomized controlled trials: An example from DECAAF II. Heart Rhythm 2025, 22: 3035-3041. PMID: 39814192, DOI: 10.1016/j.hrthm.2025.01.008.Peer-Reviewed Original Research
2024
Machine Learning‐Driven Identification of Distinct Persistent Atrial Fibrillation Phenotypes: A Cluster Analysis of DECAAF II
Noujaim C, Feng H, Bidaoui G, Huang C, Younes H, Assaf A, Mekhael M, Chouman N, Lim C, Donnellan E, Shamaileh G, Hajjar A, Nelson D, Dhore A, Li D, Marrouche N, Kreidieh O. Machine Learning‐Driven Identification of Distinct Persistent Atrial Fibrillation Phenotypes: A Cluster Analysis of DECAAF II. Journal Of Cardiovascular Electrophysiology 2024, 36: 457-466. PMID: 39716785, DOI: 10.1111/jce.16554.Peer-Reviewed Original ResearchPersonalization of primary prevention: Exploring the role of coronary artery calcium and polygenic risk score in cardiovascular diseases
Mekhael M, Bidaoui G, Falloon A, Pandey A. Personalization of primary prevention: Exploring the role of coronary artery calcium and polygenic risk score in cardiovascular diseases. Trends In Cardiovascular Medicine 2024, 35: 154-163. PMID: 39442739, DOI: 10.1016/j.tcm.2024.10.003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsComputed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseDecision Support TechniquesGenetic Predisposition to DiseaseGenetic Risk ScoreHeart Disease Risk FactorsHumansMultifactorial InheritancePhenotypePrecision MedicinePredictive Value of TestsPrimary PreventionPrognosisRisk AssessmentRisk FactorsVascular CalcificationLesion monitoring parameters as predictors of atrial arrhythmia recurrence after catheter ablation in persistent AF: A DECAAF II sub‐analysis
Mekhael M, Feng H, Younes H, Chouman N, Assaf A, Lim C, Huang C, Donnellan E, Rao S, Marrouche N, Kreidieh O. Lesion monitoring parameters as predictors of atrial arrhythmia recurrence after catheter ablation in persistent AF: A DECAAF II sub‐analysis. Journal Of Cardiovascular Electrophysiology 2024, 35: 2414-2422. PMID: 39402875, PMCID: PMC11650416, DOI: 10.1111/jce.16438.Peer-Reviewed Original ResearchBody mass index as a determinant of scar formation post‐AF ablation: Insights from DECAAF II
Bidaoui G, Tsakiris E, Younes H, Feng H, Assaf A, Chouman N, Bsoul M, Polo F, Jia Y, Liu Y, Lim C, Chamoun N, Mekhael M, Noujaim C, Pandey A, Rao S, Kreidieh O, Marrouche N, Donnellan E. Body mass index as a determinant of scar formation post‐AF ablation: Insights from DECAAF II. Journal Of Cardiovascular Electrophysiology 2024, 35: 2330-2341. PMID: 39350356, PMCID: PMC11650536, DOI: 10.1111/jce.16448.Peer-Reviewed Original Research