Manuel Avedissian, MD, MS
YCCI Assistant Director, Research CoordinationDownloadHi-Res Photo
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YCCI Assistant Director, Research Coordination
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Manuel Avedissian's published research.
Joseph Paul Eder, MD
Publications
2021
Ceralasertib-Mediated ATR Inhibition Combined With Olaparib in Advanced Cancers Harboring DNA Damage Response and Repair Alterations (Olaparib Combinations)
Mahdi H, Hafez N, Doroshow D, Sohal D, Keedy V, T. K, LoRusso P, Jürgensmeier J, Avedissian M, Sklar J, Glover C, Felicetti B, Dean E, Mortimer P, Shapiro GI, Eder JP. Ceralasertib-Mediated ATR Inhibition Combined With Olaparib in Advanced Cancers Harboring DNA Damage Response and Repair Alterations (Olaparib Combinations). JCO Precision Oncology 2021, 5: 1432-1442. PMID: 34527850, PMCID: PMC8437220, DOI: 10.1200/po.20.00439.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsHigh-grade serous ovarian cancerComplete responseResponse rateClinical benefit ratePartial response ratePrimary end pointOverall response rateHomologous recombination repair deficiencySerous ovarian cancerPoly (ADP-ribose) polymerase (PARP) inhibitorsPrior therapyUnacceptable toxicityEntire cohortRefractory cancerBenefit rateOvarian cancerPromising therapyPatientsBasket trialsDay 1End pointOlaparibPolymerase inhibitorsTherapyAdditional studies
2016
Training Persons with Spinal Cord Injury to Ambulate Using a Powered Exoskeleton.
Asselin PK, Avedissian M, Knezevic S, Kornfeld S, Spungen AM. Training Persons with Spinal Cord Injury to Ambulate Using a Powered Exoskeleton. J Vis Exp 2016 PMID: 27340808, DOI: 10.3791/54071.Peer-Reviewed Educational Materials
2013
Improved motor performance in chronic spinal cord injury following upper-limb robotic training.
Cortes M, Elder J, Rykman A, Murray L, Avedissian M, Stampas A, Thickbroom GW, Pascual-Leone A, Krebs HI, Valls-Sole J, Edwards DJ. Improved motor performance in chronic spinal cord injury following upper-limb robotic training. NeuroRehabilitation 2013, 33: 57-65. PMID: 23949034, DOI: 10.3233/NRE-130928.Peer-Reviewed Original Research