Linhui Xie

Dr. Linhui Xie earned his Ph.D. in Electrical and Computer Engineering from Purdue University in 2024. During his doctoral studies, he contributed to advancing our understanding of Alzheimer’s disease as a research assistant at the Indiana Alzheimer’s Disease Research Center, where he developed interpretable deep learning and multi-omic integration methods. In 2023, he further expanded his expertise as a visiting student at the University of Pennsylvania, exploring latent space representations to enhance genetic association studies in neurodegenerative disorders.

Currently, Dr. Xie is a postdoctoral associate in the Department of Biomedical Informatics and Data Science at Yale School of Medicine with Dr. María Rodríguez Martínez. His research focuses on computational modeling, bioinformatics, computational systems biology, and interpretable AI. He applies integrative approaches, such as heterogeneous multi-omic data analysis, neuroimaging, and pathway modeling, to investigate neurodegeneration and human brain connectomes. At Yale, he leverages interpretable AI methods to study T cell receptor binding, B cell development, and autoimmune disease mechanisms.

Dr. Xie is inspired by Yale BIDS’ collaborative spirit and its world-renowned interdisciplinary research team. Reflecting on his enthusiasm, he shares: "What excites me most about joining Yale BIDS is the collaborative spirit within its world-renowned interdisciplinary research team. It offers phenomenal training at the intersection of biomedical data science and computational modeling. I am thrilled and eager to gain expertise in data-driven methods to accelerate discoveries in immunology."

Outside of work, Dr. Xie enjoys cycling, running, swimming, cooking, and spending time with his family. One of his most memorable adventures was a 25-day cycling journey spanning approximately 1,300 miles through breathtaking landscapes and high-altitude mountains, blending his love for physical challenges and the outdoors.