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Kevin Sheth, MD

Professor of Neurology and Neurosurgery; Associate Chair for Clinical Research, Department of Neurology; Division Chief, Neurocritical Care and Emergency Neurology

Contact Information

Kevin Sheth, MD

Patient Care Locations

Mailing Address

  • Neurology

    PO Box 208018

    New Haven, CT, 06520-8018

    United States



After completing training in neurology and a fellowship in vascular neurology and neuro-critical care at Harvard, he was appointed the first neurology trained neuro-intensivist at the University of Maryland and R Adams Cowley Shock Trauma Center. At Yale, he is the founding Chief of the Division of Neurocritical Care & Emergency Neurology and Associate Chair for Clinical Research for the Department of Neurology. His interests are in the advancement of therapies for devastating acute neurological syndromes, especially those complicated by brain ischemia, swelling and hemorrhage. He is a nationally recognized clinical and translational scientist and has directed several multicenter studies. In pioneering the development of new strategies to treat brain swelling, his work has changed the fundamental approach to brain injury in the ICU and spurned the creation of new technologies in drug delivery and neuroimaging. His research group uses clinical trials as a platform for discovery, which includes novel imaging and serum based biomarkers for the neuro-ICU. In recent years, this platform has expanded to trials of prevention and recovery in brain injury. His team at Yale has served as a national model for academic critical care neurology units.

He is currently the principal investigator for two NIH U24 Neuroscience Networks, NeuroNEXT and StrokeNet and three additional RO1/UO1 awards from the NIH. Dr. Sheth has served as PI or co-PI for 8 multicenter clinical trials in stroke, as well as chair for clinical endpoint and data safety monitoring committees for several pivotal studies. He is the winner of the prestigious Robert Siekert Award from the American Heart Association (AHA) and the Derek Denny Brown Award from the American Neurological Association. His research has been funded by the NIH, American Academy of Neurology, AHA, and the US Army. Dr. Sheth is the author of over 200 publications and has served on study sections for the NIH, AHA, FDA and NASA. He is an Associate Editor at Neurology and on the editorial boards for Stroke and Neurosurgery. His work has been showcased in The Washington Post, Wall Street Journal, NPR and CNN.

Finally, Dr. Sheth has formed exciting partnerships with entrepreneurs, pharmaceutical companies, and medical device start-ups to bring forward highly innovative solutions. These efforts have resulted in extensive knowledge of FDA pathways, development of phase I-III drug programs, and implementation of new technology into the clinical workspace. His highly collaborative work is dedicated to the improved understanding of neurological disease in the critically ill. Dr. Sheth is committed to the care of his patients with acute brain injury.

Education & Training

  • Fellow, Vascular Neurology & Neurocritical Care
    Massachusetts General Hospital/Brigham & Women's Hospital (2009)
  • Chief Resident
    Massachusetts General Hospital/Brigham & Women's Hospital (2007)
  • Resident
    Massachusetts General Hospital/Brigham & Women's Hospital (2006)
  • Intern
    Brigham and Women's Hospital (2004)
  • MD
    University of Pennsylvania Medical School (2003)
  • BA
    Johns Hopkins University (1999)

Honors & Recognition

AwardAwarding OrganizationDate
Team Science AwardAssociation for Clinical and Translational Science2020
Derek Denny-Brown Young Neurological Scholar AwardAmerican Neurological Association2017
Stroke Care in Emergency Medicine AwardAmerican Heart Association/American Stroke Association2017
Family Centered Care Innovation AwardSociety for Critical Care Medicine2017
Robert G. Siekert Stroke Investigator AwardAmerican Heart Association/American Stroke Association2013
Visiting Professor Award, Mannheim GermanyGerman Society of Neurocritical Care and Emergency Medicine (ANIM) Conference2012
Clinician Scientist AwardPassano Foundation2012
Best Scientific Abstract28th Princeton Stroke Conference2012
Inducted as FellowAmerican Heart Association2012
Clinical Research AwardAmerican Heart Association2011
Clinical Research AwardAmerican Academy of Neurology2010
Alpha Omega AlphaUniversity of Pennsylvania School of Medicine2002
Phi Beta KappaJohns Hopkins University1999

Professional Service

American Society for Clinical InvestigationMember2020 - Present
NINDSNSD-K Clinical Trials Study Section2012 - Present
National Aeronautics Space Administration (NASA)Research and Technology Development to Support Crew Health and Performance in Space Exploration Missions – “Visual Impairment and Intracranial Pressure in Astronauts”2012 - Present
American Heart AssociationProfessional Education Committee2011 - Present
Neurocritical Care SocietyNeurocritical Care Research Network Executive Committee2011 - Present

Departments & Organizations