Skip to Main Content

Jonathan Koff MD

Associate Professor Term; Director, Adult Cystic Fibrosis Program

Contact Information

Jonathan Koff, MD

Patient Care Locations

Lab Location

Office Location

Mailing Address

  • PO Box 208057, 300 Cedar Street

    New Haven, CT, 06520-8057

    United States

Jonathan Koff
DownloadHi-Res Photo


Dr. Koff received his undergraduate degree from Hamilton College and his medical degree from Case Western Reserve University. He completed residency training in Internal Medicine at Brown University. He then completed fellowship training in Pulmonary & Critical Care Medicine at the University of California, San Francisco (UCSF). This included research in the Cardiovascular Research Institute in the laboratory of his mentor, Jay A. Nadel, M.D., and dedicated fellowship training in adult cystic fibrosis and lung transplantation. Dr. Koff joined the faculty at UCSF where his clinical responsibilities included: Associate Director of the Adult Cystic Fibrosis Program and member of the Lung Transplantation Program. Dr. Koff joined the faculty at Yale University in 2011 to Direct the Adult Cystic Fibrosis Program and to continue his research that focuses on pulmonary immunology.

Education & Training

  • MD
    Case Western Reserve University School of Medicine (2000)
  • BA
    Hamilton College, World Politics Major (1993)
  • Fellowship
    University of California - San Francisco
  • Fellowship
    University of California - San Francisco
  • Residency
    Brown University Alpert Medical School
  • Board Certification
    AB of Internal Medicine, Pulmonary Disease (2005, recertified: 2015)
  • Board Certification
    AB of Internal Medicine, Critical Care Medicine (Internal Medicine) (2006, recertified: 2016)

Honors & Recognition

AwardAwarding OrganizationDate
Gilead Sciences Research ScholarCystic Fibrosis2013
New Haven’s FinestConnecticut Chapter, Cystic Fibrosis Foundation2013
Cystic Fibrosis Foundation Center Quality Award (presented to Yale CF Center by national Cystic Fibrosis Foundation)National Cystic Fibrosis Foundation2011
Mentored Clinical Scientist Development Award (K08 HL0923288)NIH2009, 2014
Fellowship Travel AwardFederation of Clinical Immunology Societies (FOCIS) Conference2009
Adult Care Excellence (PACE) AwardCystic Fibrosis Foundation Program2009
5th Year Fellowship Award (RT 49233N)Cystic Fibrosis Foundation2008
Ruth L. Kirschstein National Research Service Award NIH (NRSA: F32HL088822-01)2007
Excellence in Direct TeachingHaile T. Debas Academy of Medical2006
Resident Teaching AwardDepartment of Medicine Brown University2003
Frederick C. Robbins AwardCase Western Reserve University School of Medicine2000
Raymond Kiwala Award for ExcellenceCase Western Reserve University School of Medicine1998
International Health Fellowship AwardCase Western Reserve University School of Medicine1997

Professional Service

UCSFMember2019 - Present
UCSFMember2015 - 2019
Cystic Fibrosis Foundation Research Development Program, University of California San FranciscoReviewer2015 - Present
American Thoracic Society, Respiratory, Cell, and Molecular Biology Assembly Mentoring ProgramMentor2014 - Present
Board of Directors, Connecticut Chapter of the Cystic Fibrosis FoundationMember2014 - Present
Fellowship Applicant Evaluations, Section of Pulmonary, Critical Care & Sleep MedicineInterviewer2012 - Present
Yale University Cystic Fibrosis Family DayVolunteer2012 - Present
American Journal of Respiratory Cell and Molecular Biology, American Journal of Physiology- Lung Cellular and Molecular Physiology, Cytokine, DrugsReviewer2010 - Present
American Thoracic SocietyMember2003 - Present

Departments & Organizations