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John K Forrest

MD, FACC, FSCAI
Associate Professor of Medicine (Cardiovascular Medicine); Director of Interventional Cardiology, Cardiovascular Medicine; Director of Structural Heart Disease, Yale Medicine; Director, Structural Heart Disease Program, Cardiovascular Medicine

Contact Information

John K Forrest, MD, FACC, FSCAI

Patient Care Location

Mailing Address

  • Cardiovascular Medicine

    PO Box 208017

    New Haven, CT 06520-8017

    United States

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Related Links

Yale Medicine

Patient Care

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Appointments

Education & Training

  • Fellowship
    Yale University School of Medicine (2012)
  • Fellowship
    Yale University (2010)
  • Residency
    Yale-New Haven Hospital/Traditional Program (2008)
  • Internship
    Yale-New Haven Hospital/Traditional Program (2006)
  • MD
    Yale University School of Medicine (2005)
  • BS
    Bowdoin College, History and Biochemistry

Activities

  • Transcatheter Versus Surgical Aortic Valve Replacement in Aortic Stenosis Patients at Low Surgical Risk: 3-year Outcomes from the Evolut Low Risk Trial
    Hangzhou, China 2023
    Transcatheter Versus Surgical Aortic Valve Replacement in Aortic Stenosis Patients at Low Surgical Risk: 3-year Outcomes from the Evolut Low Risk Trial
  • EVOLUT: New Trials, New Technologies (OPTIMIZE PRO and SMART)
    Boston, MA, United States 2022
    EVOLUT: New Trials, New Technologies (OPTIMIZE PRO and SMART)
  • TAVR and Bicuspid Aortic Valve Disease: Update on the Evidence
    Boston, MA, United States 2022
    TAVR and Bicuspid Aortic Valve Disease: Update on the Evidence
  • Cerebral Embolic Protection in TAVR: Selective use in Vulnerable Patients
    Boston, MA, United States 2022
    Cerebral Embolic Protection in TAVR: Selective use in Vulnerable Patients
  • The Evolut Supra‐Annular, Self‐Expanding Transcatheter Aortic Bioprosthesis Provides Symmetric Scaffolding for Optimal Leaflet Coaptation Despite Variable Annular Morphology
    Boston, MA, United States 2022
    The Evolut Supra‐Annular, Self‐Expanding Transcatheter Aortic Bioprosthesis Provides Symmetric Scaffolding for Optimal Leaflet Coaptation Despite Variable Annular Morphology
  • My "Best Practice’" Routine Bicuspid TAVR
    Miami, FL, United States 2022
    My "Best Practice’" Routine Bicuspid TAVR
  • TAVR in Bicuspid Valves Technical Pearls: Valve Choice, Sizing, and Positioning
    Chicago, IL, United States 2022
    TAVR in Bicuspid Valves Technical Pearls: Valve Choice, Sizing, and Positioning
  • Progress in Self-Expanding TAVR: Evolut PRO Plus and Beyond
    Chicago, IL, United States 2022
    Progress in Self-Expanding TAVR: Evolut PRO Plus and Beyond
  • Cerebral Embolic Protection and TAVR
    Orlando, FL, United States 2021
    Cerebral Embolic Protection and TAVR
  • TAVR for Bicuspid Aortic Stenosis: Temporal Trends and Outcomes
    Hangzhou, China 2021
    TAVR for Bicuspid Aortic Stenosis: Temporal Trends and Outcomes
  • Between a Rock and a Hard Place: Calcium, Calcium, and More Calcium
    Miami, FL, United States 2021
    Between a Rock and a Hard Place: Calcium, Calcium, and More Calcium
  • Balancing Contemporary Bicuspid Data
    Miami, FL, United States 2021
    Balancing Contemporary Bicuspid Data
  • Complete 2-year Follow-Up from Evolut Low Risk Trial
    Miami, FL, United States 2021
    Complete 2-year Follow-Up from Evolut Low Risk Trial
  • TAVR in Women and Bicuspids
    Virtual Meeting 2021
    TAVR in Women and Bicuspids
  • Management of Coronary Disease Pre-and Post TAVR: Guidelines, Tips and Tricks
    On-line Virtual Conference 2020
    Management of Coronary Disease Pre-and Post TAVR: Guidelines, Tips and Tricks
  • TAVR Optimization Strategies in Complex Anatomies: Bicuspid
    Virtual Conference 2020
    TAVR Optimization Strategies in Complex Anatomies: Bicuspid
  • Updates of Evolut Low Risk Trial
    Hangzhou, China 2020
    Updates of Evolut Low Risk Trial
  • Primary Results of Evolut Low Risk Bicuspid Study
    Hangzhou, China 2020
    Primary Results of Evolut Low Risk Bicuspid Study
  • Blueprint for Bicuspid Treatment: TAVR Implant Strategies for Bicuspid Patients
    Virtual Conference 2020
    Evolut Platform: Design Features, Outcomes, Implantation Tips and Tricks and Future Visions
  • Critical Review of Evidence: TAVR in Low Risk Bicuspid Patients
    Virtual Conference 2020
    Critical Review of Evidence: TAVR in Low Risk Bicuspid Patients
  • TAVR Foundations for Fellows
    San Francisco, CA, United States 2019
    TAVR Foundations for Fellows
  • TAVR in Bicuspid Aortic Valves
    San Francisco, CA, United States 2019
    TAVR in Bicuspid Aortic Valves
  • TAVR with High Risk for Coronary Obstruction
    San Francisco, CA, United States 2019
    TAVR with High Risk for Coronary Obstruction
  • Incidence and Outcomes of Patient-Prosthesis Mismatch Following Self-expanding Transcatheter Aortic Valve Replacement: An Analysis From the STS/ACC TVT Registry
    San Francisco, CA, United States 2019
    Incidence and Outcomes of Patient-Prosthesis Mismatch Following Self-expanding Transcatheter Aortic Valve Replacement: An Analysis From the STS/ACC TVT Registry
  • Latest Clinical Data in Bicuspid Disease
    Chicago, IL, United States 2019
    Latest Clinical Data in Bicuspid Disease
  • Transcatheter Therapies: Potential Realized
    New Orleans, LA, United States 2019
    Transcatheter Therapies: Potential Realized
  • Valvular Heart Disease in 2019: A Field Transformed
    New Orleans, LA, United States 2019
    Valvular Heart Disease in 2019: A Field Transformed
  • Con: Cerebral Embolic Protection is a Niche Concept
    Las Vegas, NV, United States 2019
    Con: Cerebral Embolic Protection is a Niche Concept
  • New Technologies for Brain Protection During TAVR
    Las Vegas, NV, United States 2019
    New Technologies for Brain Protection During TAVR
  • TAVR in Patients with a Bicuspid Anatomy
    New York, NY, United States 2019
    TAVR in Patients with a Bicuspid Anatomy
  • Self-Expanding Transcatheter Aortic Valve Replacement in Patients with Severe Aortic Stenosis and Bicuspid Morphology: A Report from the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry
    Washington, DC, United States 2019
    Self-Expanding Transcatheter Aortic Valve Replacement in Patients with Severe Aortic Stenosis and Bicuspid Morphology: A Report from the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry
  • TAVR Foundations for Fellows
    San Diego, CA, United States 2018
    TAVR Foundations for Fellows
  • The Road to Perdition: Severe Aortic Stenosis with Bicuspid Valve Disease
    San Diego, CA, United States 2018
    The Road to Perdition: Severe Aortic Stenosis with Bicuspid Valve Disease
  • Paravalvular Leak Post-TAVR
    San Diego, CA, United States 2018
    Paravalvular Leak Post-TAVR
  • Coronary Obstruction After TAVR
    San Diego, CA, United States 2018
    Coronary Obstruction After TAVR
  • 30-Day Outcomes Following Transcatheter Aortic Valve Replacement with the Evolut PRO Valve in Commercial Use: Report from the STS/ACC TVT Registry
    San Diego, CA, United States 2018
    30-Day Outcomes Following Transcatheter Aortic Valve Replacement with the Evolut PRO Valve in Commercial Use: Report from the STS/ACC TVT Registry
  • Cerebral Embolic Protection During TAVR
    San Diego, CA, United States 2018
    Cerebral Embolic Protection During TAVR
  • Structural Heart Disease in 2018: Moving from TAVR to TMVR and More
    Farmington, CT, United States 2018
    Structural Heart Disease in 2018: Moving from TAVR to TMVR and More
  • Debate: Cerebral Embolic Protection Should be Used in All (Most) Cases
    Chicago, IL, United States 2018
    Debate: Cerebral Embolic Protection Should be Used in All (Most) Cases
  • The Evolut PRO TAVR System: Confronting the Issues (Valve Sizing, New Pacemakers, Paravalvular Leak, and Extreme Calcification
    Chicago, IL, United States 2018
    The Evolut PRO TAVR System: Confronting the Issues (Valve Sizing, New Pacemakers, Paravalvular Leak, and Extreme Calcification
  • Challenging Structural Cases by the Experts: Predicting and Managing Coronary Obstruction during TAVR
    Orlando, FL, United States 2018
    Challenging Structural Cases by the Experts: Predicting and Managing Coronary Obstruction during TAVR
  • 1-Year Outcomes With the Evolut PRO Self-Expanding Repositionable Transcatheter Aortic Valve With Pericardial Wrap
    Orlando, FL, United States 2018
    1-Year Outcomes With the Evolut PRO Self-Expanding Repositionable Transcatheter Aortic Valve With Pericardial Wrap
  • Evolut R TAVR - Technology Review Including Evolut 34mm and PRO
    Denver, CO, United States 2017
    Evolut R TAVR - Technology Review Including Evolut 34mm and PRO
  • Low Incidence of Paravalvular Leak at 6 Months with the New Self-Expanding Repositionable Transcatheter Aortic Valve with Pericardial Wrap
    Denver, CO, United States 2017
    Low Incidence of Paravalvular Leak at 6 Months with the New Self-Expanding Repositionable Transcatheter Aortic Valve with Pericardial Wrap
  • TAVR Shift to Intermediate-Risk Patients: Practical Considerations for the Heart Team and Hospitals
    Denver, CO, United States 2017
    TAVR Shift to Intermediate-Risk Patients: Practical Considerations for the Heart Team and Hospitals
  • Evolut R Snapshots I - The New Evolut R PRO System
    Chicago, IL, United States 2017
    Evolut R Snapshots I - The New Evolut R PRO System
  • Ask the Experts - How Do I Manage These Challenge Case Scenarios?
    Chicago, IL, United States 2017
    Ask the Experts - How Do I Manage These Challenge Case Scenarios?
  • Optimizing Post-Dilation with Self-Expanding Valves - Does Balloon Choice Matter?
    Chicago, IL, United States 2017
    Optimizing Post-Dilation with Self-Expanding Valves - Does Balloon Choice Matter?
  • Will SURTAVI Change my Practice: TAVI for Patients with Intermediate Risk?
    Paris, IDF, France 2017
    Will SURTAVI Change my Practice: TAVI for Patients with Intermediate Risk?
  • Recorded Case: Transcatheter Aortic Valve Replacement using Evolut Pro Valve
    Paris, IDF, France 2017
    Recorded Case: Transcatheter Aortic Valve Replacement using Evolut Pro Valve
  • Transcatheter Mitral Valve-in-Ring with Concomitant Para-Ring Leak Closure
    Paris, IDF, France 2017
    Transcatheter Mitral Valve-in-Ring with Concomitant Para-Ring Leak Closure
  • How to Build a Successful Multidisciplinary Interventional Program: Balancing Pressures of Good Practice and Good Research
    New Orleans, LA, United States 2017
    How to Build a Successful Multidisciplinary Interventional Program: Balancing Pressures of Good Practice and Good Research
  • Procedural Perfection: Ideal TAVR Using the Evolut - All the Tips and Tricks
    New Orleans, LA, United States 2017
    Procedural Perfection: Ideal TAVR Using the Evolut - All the Tips and Tricks
  • Managing Complex Paravalvular Leaks
    Atlanta, GA, United States 2017
    Managing Complex Paravalvular Leaks
  • 30-Day Safety and Echocardiographic Outcomes Following Transcatheter Aortic Valve Replacement with the Self-Expanding Repositionable Evolut PRO System
    Washington, DC, United States 2017
    30-Day Safety and Echocardiographic Outcomes Following Transcatheter Aortic Valve Replacement with the Self-Expanding Repositionable Evolut PRO System
  • Next Generation TAVI Technologies
    Prague, Prague, Czech Republic 2017
    Next Generation TAVI Technologies
  • How to Mitigate the Risk of PVL post TAVR
    Prague, Prague, Czech Republic 2017
    How to Mitigate the Risk of PVL post TAVR
  • Transcatheter Aortic Valve Replacement in Women Versus Men: An Analysis of the CoreValve US Pivotal and Continued Access Trials
    San Francisco, CA, United States 2015
    Transcatheter Aortic Valve Replacement in Women Versus Men: An Analysis of the CoreValve US Pivotal and Continued Access Trials
  • Current Status of TAVR with the Self-Expanding CoreValve System
    Atlanta, GA, United States 2015
    Current Status of TAVR with the Self-Expanding CoreValve System
  • Debate: Is TAVR or SAVR More Appropriate for All Comers: Pro
    Atlanta, GA, United States 2015
    Debate: Is TAVR or SAVR More Appropriate for All Comers: Pro
  • Complex Cases Using a Self-Expanding TAVR
    Atlanta, GA, United States 2015
    Complex Cases Using a Self-Expanding TAVR
  • US Perspective: Optimizing Patient Selection and Imaging for TAVR
    Washington, DC, United States 2014
    US Perspective: Optimizing Patient Selection and Imaging for TAVR
  • A True Hybrid Case: Off-Pump CABG and TAVR (Direct Aortic Approach using a 31mm CoreValve) in Patient with Left Main Disease, Bicuspid Aortic Valve Stenosis, and Severe Thrombocytopenia
    Washington, DC, United States 2014
    A True Hybrid Case: Off-Pump CABG and TAVR (Direct Aortic Approach using a 31mm CoreValve) in Patient with Left Main Disease, Bicuspid Aortic Valve Stenosis, and Severe Thrombocytopenia
  • Transcatheter Aortic Valve Replacement 2014
    New London, CT, United States 2014
    Transcatheter Aortic Valve Replacement 2014
  • Innovation: New Frontier in Implantable Therapies: Clinical Need, Regulatory Challenges, and Market Opportunities
    London, England, United Kingdom 2014
    Innovation: New Frontier in Implantable Therapies: Clinical Need, Regulatory Challenges, and Market Opportunities
  • Focus of TAVR: Program, Patient Selections, and Complications
    Medellín, Antioquia, Colombia 2013
    Focus of TAVR: Program, Patient Selections, and Complications
  • Treating Iliac, SFA, and Critical Limb Ischemia - Patient Screening, Prognosis, Treatment Options and Outcomes
    Medellín, Antioquia, Colombia 2013
    Treating Iliac, SFA, and Critical Limb Ischemia - Patient Screening, Prognosis, Treatment Options and Outcomes
  • Recorded Case: Retrograde RCA CTO via RV Marginal: The Beating Corsair
    Miami, FL, United States 2012
    Recorded Case: Retrograde RCA CTO via RV Marginal: The Beating Corsair
  • Complex Carotid Stenting
    Orlando, FL, United States 2011
    Complex Carotid Stenting
  • Evaluation of everolimus-eluting and paclitaxel eluting stents in patients with jailed side branches: two-year results from the SPIRIT IV trial
    Paris, IDF, France 2011
    Evaluation of everolimus-eluting and paclitaxel eluting stents in patients with jailed side branches: two-year results from the SPIRIT IV trial
  • Device Choices for Percutaneous Aortic Paravalvular Leak Closure
    Vancouver, BC, Canada 2011
    Device Choices for Percutaneous Aortic Paravalvular Leak Closure

Honors & Recognition

AwardAwarding OrganizationDate
ACC Emerging Leadership FacultyAmerican College of Cardiology2019
Yale Advanced Emerging Leadership Program2017
Fellow of the American College of Cardiology2016
Yale-New Haven Hospital Nurses Choice Award2016
Fellow of the Society for Cardiovascular Angiography and Interventions2015
The John P. Peters PrizeYale School of Medicine2005
NIH/NHLBI Student Research Grant AwardNIH/NHLBI2004
Yale Club of New Haven ScholarYale Club of New Haven2001, 2002, 2003, 2004
NIH Summer Research Fellowship AwardNIH2001

Professional Service

OrganizationRoleDate
Yale New Haven Health SystemAortic Stenosis Care Signature Pathway2022
PROGRESS (TAVR for Moderate Aortic Stenosis and Cardiac Dysfunction) TrialNational/International Screening Committee2022 - Present
China Valve (Hangzhou)Moderator2022 - Present
Structural Heart Advisory Board, Medtronic IncBoard Member2022 - Present
Structrual Heart Data Evidence and Publications Committee, MedtronicChair2022 - Present
Yale University- Davenport CollegeFaculty Fellow at Davenport College Yale University2021 - Present
HVC Research Leadership CommitteeExecutive Committee Member2021 - Present
Yale New Haven Heath SystemLumedx Steering Committee2021 - Present
PROGRESS (TAVR for Moderate Aortic Stenosis and Cardiac Dysfunction) TrialNational/International Steering Committee2021 - Present
EVOLUT R Low Risk Randomized Clinical TrialNational/International Principal Investigator2021 - Present
American College of CardiologySTS/ACC TVT Mitral Risk Model Committee2021 - Present
Transcatheter Valve Therapies (TVT)Annual Meeting2021 - Present
New England Structural Heart ConsortiumAnnual Meeting2021 - Present
St. Thomas Day SchoolChairman Board 2021-present2021 - Present
New England Structural Heart ConsortiumAnnual Meeting2021 - Present
New England Structural Heart ConsortiumAnnual Meeting2021 - Present
Journal of American College of Cardiology (JACC)Guest Editor2021 - Present
Journal of the American Medical Association (JAMA)Reviewer2021 - Present
Journal of the Society for Cardiovascular Angiography (JSCAI)Editorial Board Member2021 - Present
Journal of the Society for Cardiovascular Angiography (JSCAI)Reviewer2021 - Present
Journal of American College of Cardiology (JACC)Reviewer2020 - Present
JAMA CardiologyReviewer2020 - Present
St. Thomas Day SchoolBoard Vice President2019 - 2021
Society for Cardiovascular Angiography and Interventions (SCAI)Annual Meeting2019 - 2020
Transcatheter Cardiovascular Therapeutics (TCT)Annual Meeting Abstract Review Committee2019 - Present
Society for Cardiovascular Angiography and InterventionsAnnual Meeting2019 - Present
Transcatheter Cardiovascular TherapeuticsAbstract Selection Committee2019 - Present
Global Advisory Board, Medtronic IncBoard Member2019 - Present
New England Structural Heart Annual MeetingCo-Director2018 - Present
New England Structural Heart ConsortiumBoard of Directors2018 - Present
BICUSPID TAVR Clinical TrialNational Steering Committee2018 - 2020
BICUSPID TAVR Clinical TrialNational Screening Committee2018 - 2020
REFLECT 3 Clinical TrialNational Screening Committee2018 - 2020
Yale University School of MedicineMission Statement Committee2018 - 2019
New England Structural Heart ConsortiumFounding Member2018
BICUSPID TAVR Clinical TrialNational Principal Investigator2018 - Present
APOLLO Transcatheter Mitral Valve Replacement Clinical TrialNational Screening Committee2018 - Present
APOLLO Transcatheter Mitral Valve Replacement Clinical TrialNational Steering Committee2018 - Present
American College of CardiologySTS/ACC TVT TAVR Risk Model Committee2018 - Present
American College of CardiologyAbstract Selection Committee: Aortic Valve Disease2018 - Present
Transcatheter Cardiovascular Therapeutics (TCT)Annual Meeting2018 - Present
Transcatheter Valve TherapiesAnnual meeting (late breaking clinical trials, cases, innovation, moderated posters) reviewer2018 - Present
American College of CardiologyAnnual session Abstract Selection Committee Aorta Valve Disease2018 - Present
Journal of American College of Cardiology - Cardiovascular Interventions (JACC- Intervenions)Reviewer2018 - Present
Yale University School of MedicineQuality Committee2017 - 2019
Yale New Haven Health SystemYale New Haven Health Systems Quality Committee2017 - 2019
American College of CardiologyTVT Dataset Update Working Group2017 - 2019
Yale New Haven HospitalHVC/ED Collaborative2017 - Present
TAVR UNLOAD Clinical TrialNational Screening Committee2017 - Present
EVOLUT R Low Risk Randomized TAVR TrialNational Steering Committee2017 - Present
Transcatheter Valve Therapies (TVT)Annual Meeting2017 - Present
American College of CardiologyTVT Dataset Update2017 - Present
Transcatheter Valve Therapies (TVT)Abstract Grader 2017 - Present
Transcatheter Cardiovascular TherapiesAnnual meeting Session Chair2017 - Present
Transcatheter Valve TherapiesAnnual meeting, Abstract Selection Committee2017 - Present
Transcatheter Valve TherapiesAnnual meeting Session Chair2017 - Present
AortaEditorial Board Member2017 - Present
US Advisory Board, Boston ScientificBoard Member2017 - Present
TAVR 2.0 Clinical TrialChair of National Steering Committee2016 - 2018
TAVR 2.0 Clinical TrialChair of National Screening Committee2016 - 2017
Yale University School of MedicineHeart Care Team2016 - Present
TAVR 2.0 Clinical TrialNational Principal Investigator2016 - Present
Structural Heart Advisory Board, Edwards LifesciencesBoard Member2016 - Present
Yale-New Haven HospitalYale-New Haven Patient Experience Committee2015 - 2020
St. Thomas Day SchoolMember Board of Governor's2015 - 2019
FANTOM II Clinical TrialData Safety Monitoring Board (DSMB)2015 - 2018
ABLATE Clinical TrialClinical Event Committee (CEC)2015 - 2016
Yale University School of MedicineYale Medical Leadership Council2015 - Present
Yale New Haven HospitalYale medical Leadership Committee (MLC/JLC)2015 - Present
MedtronicMedtronic Fundamentals of TAVR Fellows Course Co-Director2015 - Present
EdwardsEdwards TAVR Fellows Course Co-Director2015 - Present
MedtronicMedtronic Advanced Users Evolut R Program Co-Chair2015 - Present
American Journal of Cardiology, Catheterization and Cardiovascular InterventionsReviewer2015 - Present
Fundamentals of TAVR, Medtronic IncCo-Director2015 - Present
DEFLECT III Clinical TrialClinical Event Committee (CEC)2014 - 2015
Transcatheter Valve Therapies (TVT)Annual Meeting2014 - Present
DEFLECT II Clinical TrialClinical Event Committee (CEC)2013 - 2014
Transcatheter Cardiovascular Therapeutics (TCT)Annual Meeting2013 - Present
DEFLECT I Clinical TrialClinical Event Committee (CEC)2012 - 2013

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