Jesus Maldonado Vazquez
Associate Research ScientistCards
About
Research
Publications
2026
Silicon photonic biosensor for the detection of an epileptic biomarker
Maldonado J, Gu Y, Zhao J, Zaveri H. Silicon photonic biosensor for the detection of an epileptic biomarker. Progress In Biomedical Optics And Imaging 2026, 13842: 5. DOI: 10.1117/12.3080904.Peer-Reviewed Original Research
2025
Rapid Multianalyte Quantification of Brain Chemistry Using Si-Nanoribbon Bio-Field-Effect Transistor Sensors
Maldonado J, Rajagopalan V, Gu Y, Eid T, Spencer D, Zaveri H. Rapid Multianalyte Quantification of Brain Chemistry Using Si-Nanoribbon Bio-Field-Effect Transistor Sensors. ACS Applied Materials & Interfaces 2025, 17: 59148-59160. PMID: 41104714, DOI: 10.1021/acsami.5c15695.Peer-Reviewed Original ResearchConceptsSemiconductor field effect transistorReal-time biosensingField-effect transistorsSi nanoribbonsLimit of detectionGamma-aminobutyric acidReal-time detection capabilityArtificial cerebrospinal fluidNanowire devicesComplex biological matricesContinuous real-time monitoringTransistor sensorsLabel-free detectionSurface functionalizationBiological matricesExcitatory-inhibitory balanceSensor surfaceAptamer bioreceptorsBuffer solutionSensorNanosensing platform
2024
A CMOS Nanosensing System For Continuous Brain Multianalyte Monitoring
Gu Y, Vazquez J, Murray D, Zaveri H, Spencer D. A CMOS Nanosensing System For Continuous Brain Multianalyte Monitoring. 2024, 00: 693-697. DOI: 10.1109/ectc51529.2024.00113.Peer-Reviewed Original Research
2023
Recognition of the interaction between the bioactive peptide Val–Pro–Pro and the minimal promoter region of genes SOD and CAT using QCM-D and docking studies
Pérez-Vielma N, Gómez-López M, Maldonado J, Correa-Basurto J, Martínez-Godínez M, Miliar-García Á. Recognition of the interaction between the bioactive peptide Val–Pro–Pro and the minimal promoter region of genes SOD and CAT using QCM-D and docking studies. Analytical Methods 2023, 15: 2979-2988. PMID: 37309667, DOI: 10.1039/d3ay00265a.Peer-Reviewed Original ResearchProgress in Plasmonic Sensors as Monitoring Tools for Aquaculture Quality Control
Quintanilla-Villanueva G, Maldonado J, Luna-Moreno D, Rodríguez-Delgado J, Villarreal-Chiu J, Rodríguez-Delgado M. Progress in Plasmonic Sensors as Monitoring Tools for Aquaculture Quality Control. Biosensors 2023, 13: 90. PMID: 36671925, PMCID: PMC9856096, DOI: 10.3390/bios13010090.Peer-Reviewed Original ResearchConceptsSource of high-quality proteinFish meat productsHigh-quality proteinsWorld's growing populationMeat productsFish healthNutritional significanceFarm facilitiesAquaculturePathogen outbreaksCommercial stageBiochemical indicatorsEnvironmental pollutionFiber-optic surface plasmon resonanceSolvent useSample pre-treatmentEnvironmental hazardsSurface plasmon resonancePlasmonic-based sensorsPre-treatmentBiosecurityLack of traceabilityFarmsFishMonitoring tool
2022
Current Trends in Photonic Biosensors: Advances towards Multiplexed Integration
Ramirez J, García D, Maldonado J, Fernández-Gavela A. Current Trends in Photonic Biosensors: Advances towards Multiplexed Integration. Chemosensors 2022, 10: 398. DOI: 10.3390/chemosensors10100398.Peer-Reviewed Original ResearchLab-on-a-chipSurface plasmon resonancePhotonic biosensorsPhotonic crystalsLab-on-a-chip biosensorsRing resonatorLab-on-a-chip platformsMicrofluidic cellInterferometric biosensorBiosensorPlasmon resonanceResonanceMultiplex integrationOpticsReal-life diseasesCommercial solutionsDetection principlePhotonsA Fully Integrated CMOS-controlled Scalable Microfluidics and Pneumatic-free Cell Actuation and Cytometry Sensing Device
Zhu C, Maldonado J, Sengupta K. A Fully Integrated CMOS-controlled Scalable Microfluidics and Pneumatic-free Cell Actuation and Cytometry Sensing Device. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2022, 00: 1279-1282. PMID: 36086451, DOI: 10.1109/embc48229.2022.9871457.Peer-Reviewed Original ResearchConceptsChip-scale systemsSilicon-based integrated circuitsLow costEnd-to-endCMOS chipDriving capabilityCell actuatorsBiomedical applicationsMassive scaleComplex computationsMoore's lawSensing systemSystem complexitySeparation capabilityReal-timeSensing platformSyringe pumpPoint-of-care diagnostic platformCapabilityCMOSActuatorPlatformSensingCircuitChip
2021
CMOS-Based Electrokinetic Microfluidics With Multi-Modal Cellular and Bio-Molecular Sensing for End-to-End Point-of-Care System
Zhu C, Maldonado J, Sengupta K. CMOS-Based Electrokinetic Microfluidics With Multi-Modal Cellular and Bio-Molecular Sensing for End-to-End Point-of-Care System. IEEE Transactions On Biomedical Circuits And Systems 2021, 15: 1250-1267. PMID: 34914597, DOI: 10.1109/tbcas.2021.3136165.Peer-Reviewed Original ResearchConceptsEnd-to-endBio-molecular sensingMassive scalabilityFluid flowChip-scale systemsElectrokinetic fluid flowEnd-to-end systemFluid flow controlBio-sensing devicesCompact form factorCMOS ICsFlow controlFluid velocityMicrofluidic channelSilicon chipReceiver arrayLP processBased assayPOC diagnosticsDesign spaceCMOSPoint-of-care systemElectrode arrayMulti-ModalCell manipulationCMOS-Driven Pneumatic-Free Scalable Microfluidics and Fluid Processing with Label-Free Cellular and Bio-Molecular Sensing Capability for an End-to-End Point-of-Care System
Zhu C, Maldonado J, Tang H, Venkatesh S, Sengupta K. CMOS-Driven Pneumatic-Free Scalable Microfluidics and Fluid Processing with Label-Free Cellular and Bio-Molecular Sensing Capability for an End-to-End Point-of-Care System. 2021, 64: 278-280. DOI: 10.1109/isscc42613.2021.9365843.Peer-Reviewed Original ResearchEnd-to-endEnd-to-end systemHandheld platformsKernel functionMolecular diagnostic platformsPoint-of-carePoint-of-care systemPoint-of-care applicationsSensing technologyAssay chemistrySensing componentsBiosensing systemAc electro-osmosisCell sensingElectro-kinetic flowPressure-driven flowPoint-of-care devicesCMOS-basedPlatformChip-scale platformDiagnostic platformCell manipulation techniquesSingular systemsCellsFlow control
2020
Ultrasensitive Label-Free Detection of Unamplified Multidrug-Resistance Bacteria Genes with a Bimodal Waveguide Interferometric Biosensor
Maldonado J, González-Guerrero A, Fernández-Gavela A, González-López J, Lechuga L. Ultrasensitive Label-Free Detection of Unamplified Multidrug-Resistance Bacteria Genes with a Bimodal Waveguide Interferometric Biosensor. Diagnostics 2020, 10: 845. PMID: 33086716, PMCID: PMC7589074, DOI: 10.3390/diagnostics10100845.Peer-Reviewed Original ResearchMultidrug-resistant bacteriaAntimicrobial resistanceGram-negative antimicrobial resistanceManagement of healthcare-associated infectionsIncidence of deathHealthcare-Associated InfectionsAccurate therapeutic interventionsExtended-spectrumDrug resistancePatient outcomesTherapeutic interventionsDiagnostic toolGene sequencesBiosensor methodologyInfectionBacteria genesDiagnostic platformBimodal waveguide interferometerGenesAttomolar levelBacteriaPatientsSequenceClinicDrug