Jessica Gois Santana
Postgraduate AssociateAbout
Research
Publications
2026
Neoadjuvant PD-1 Inhibition prior to Partial Cryoablation of Murine Hepatocellular Carcinoma Modulates the Tumor Microenvironment toward Favorable Immunological Profiles
Kao T, Santana J, Meister E, Shewarega A, Israel J, Peschke L, Tefera J, Matuschewski N, Sobirey R, Zhang X, Gebauer B, Madoff D, Savic L, Chapiro J. Neoadjuvant PD-1 Inhibition prior to Partial Cryoablation of Murine Hepatocellular Carcinoma Modulates the Tumor Microenvironment toward Favorable Immunological Profiles. Journal Of Vascular And Interventional Radiology 2026, 37: 108585. PMID: 41690670, PMCID: PMC13052828, DOI: 10.1016/j.jvir.2026.108585.Peer-Reviewed Original Research
2025
Liver pH imaging for diagnosis and prognosis
Santana J, Kurdi S, Chapiro J, Hyder F, Coman D. Liver pH imaging for diagnosis and prognosis. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2025 DOI: 10.58530/2025/1803.Peer-Reviewed Original ResearchTransmembrane pH imaging distinguishes glycolytic and oxidative phenotypes in gliomas
Coman D, Mishra S, Kurdi S, Santana J, Hyder F. Transmembrane pH imaging distinguishes glycolytic and oxidative phenotypes in gliomas. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2025 DOI: 10.58530/2025/3064.Peer-Reviewed Original ResearchCommentary on: Comparative Analysis of Systemic Immune Responses and Metastatic Risks in Tumor Ablation: An Animal Study of Radiofrequency Ablation and Irreversible Electroporation with Immune Modulation
Gois Santana J, Chapiro J. Commentary on: Comparative Analysis of Systemic Immune Responses and Metastatic Risks in Tumor Ablation: An Animal Study of Radiofrequency Ablation and Irreversible Electroporation with Immune Modulation. CardioVascular And Interventional Radiology 2025, 48: 536-537. PMID: 40097621, DOI: 10.1007/s00270-025-04009-7.Commentaries, Editorials and LettersWomen’s Leadership Development at the Yale School of Medicine: Preliminary Evaluation of an Innovative Program
David D, Arora I, Hussein A, Santana J, Crusto C, Latimore D. Women’s Leadership Development at the Yale School of Medicine: Preliminary Evaluation of an Innovative Program. Women's Health Reports 2025, 6: whr.2024.0188. PMID: 40308350, PMCID: PMC12040562, DOI: 10.1089/whr.2024.0188.Peer-Reviewed Original Research
2024
Molecular MRI of T-cell immune response to cryoablation in immunologically hot vs. cold hepatocellular carcinoma
Santana J, Shewarega A, Nam D, Duncan J, Madoff D, Hyder F, Coman D, Chapiro J. Molecular MRI of T-cell immune response to cryoablation in immunologically hot vs. cold hepatocellular carcinoma. JHEP Reports 2024, 7: 101294. PMID: 40028344, PMCID: PMC11870164, DOI: 10.1016/j.jhepr.2024.101294.Peer-Reviewed Original ResearchEffect of Incomplete Cryoablation and Matrix Metalloproteinase Inhibition on Intratumoral CD8+ T-Cell Infiltration in Murine Hepatocellular Carcinoma.
Shewarega A, Santana J, Nam D, Berz A, Tefera J, Kahl V, Mishra S, Coman D, Duncan J, Roberts S, Wetter A, Madoff D, Chapiro J. Effect of Incomplete Cryoablation and Matrix Metalloproteinase Inhibition on Intratumoral CD8+ T-Cell Infiltration in Murine Hepatocellular Carcinoma. Radiology 2024, 310: e232365. PMID: 38349244, PMCID: PMC10902598, DOI: 10.1148/radiol.232365.Peer-Reviewed Original ResearchTransmembrane pH gradient imaging in rodent glioma models
Mishra S, Santana J, Mihailovic J, Hyder F, Coman D. Transmembrane pH gradient imaging in rodent glioma models. NMR In Biomedicine 2024, 37: e5102-e5102. PMID: 38263680, PMCID: PMC10987279, DOI: 10.1002/nbm.5102.Peer-Reviewed Original Research
2023
Hepatic Hypertrophy in Normal and Cirrhotic Livers Following Portal Vein Embolization: Comparative Assessment of 2 Different Embolic Regimens in a Large Animal Model
Kuhn T, Kahl V, Wang Y, Berz A, Shewarega A, Santana J, Antoch G, Chapiro J, Schlachter T, Madoff D. Hepatic Hypertrophy in Normal and Cirrhotic Livers Following Portal Vein Embolization: Comparative Assessment of 2 Different Embolic Regimens in a Large Animal Model. Journal Of Vascular And Interventional Radiology 2023, 34: 2162-2172.e2. PMID: 37634850, DOI: 10.1016/j.jvir.2023.08.024.Peer-Reviewed Original ResearchPredicting tumor recurrence on baseline MR imaging in patients with early-stage hepatocellular carcinoma using deep machine learning
Kucukkaya A, Zeevi T, Chai N, Raju R, Haider S, Elbanan M, Petukhova-Greenstein A, Lin M, Onofrey J, Nowak M, Cooper K, Thomas E, Santana J, Gebauer B, Mulligan D, Staib L, Batra R, Chapiro J. Predicting tumor recurrence on baseline MR imaging in patients with early-stage hepatocellular carcinoma using deep machine learning. Scientific Reports 2023, 13: 7579. PMID: 37165035, PMCID: PMC10172370, DOI: 10.1038/s41598-023-34439-7.Peer-Reviewed Original Research