About
Research
Overview
Anesthesia is applied neuroscience, and neuroscience uses anesthesia as a powerful experimental probe to understand how brain networks give rise to consciousness—and how disrupting those networks alters cognition and behavior.
The Helfrich Lab investigates the neurophysiology of unconscious states and their consequences for human cognition, using primarily scalp electroencephalography (EEG) to characterize shared and state-specific neural mechanisms across anesthesia, sleep, and disorders of consciousness.
Our work asks whether anesthesia can be re-engineered to more closely resemble sleep rather than coma, thereby reducing postoperative cognitive side effects while potentially harnessing sleep’s restorative functions, and whether anesthetic perturbations can serve as diagnostic probes to predict recovery trajectories in patients with coma or other disorders of consciousness. The overarching goal of this research is to translate mechanistic insights into improved clinical care for all patients.
Medical Research Interests
Academic Achievements & Community Involvement
Clinical Care
Overview
Janna D. Helfrich, MD, is an anesthesiologist who cares for adults before, during, and after surgery. She focuses on providing safe anesthesia care and supporting patients through all phases of their surgical experience.
Dr. Helfrich cares for patients with a wide range of medical conditions who need anesthesia for surgery or procedures. She monitors vital signs such as blood pressure, heart rate, and breathing, and adjusts anesthesia medications to keep patients comfortable and safe. She also has training in intensive care and prehospital emergency care, which helps her manage patients who are critically ill or at higher risk during surgery.
As an assistant professor at Yale School of Medicine, Dr. Helfrich studies how anesthesia affects the brain and consciousness. Her research uses brainwave recordings, called EEG, to compare anesthesia with natural sleep and with conditions such as coma. She aims to better understand how changes in brain activity under anesthesia may affect thinking and memory after surgery, and how this knowledge can be used to improve patient care.
Dr. Helfrich earned her medical degree and a medical doctorate from Charite University Medical Center Berlin. She completed residency training in anesthesiology at University Medical Center Tuebingen and University Medical Center Hamburg-Eppendorf, all in Germany. She also pursued fellowship training in prehospital emergency care and intensive care medicine at University Medical Center Hamburg-Eppendorf, and a postdoctoral fellowship in neuroscience at the University of California at Berkeley.
Clinical Specialties
Board Certifications
Anesthesiology
- Certification Organization
- German Board Certificate
- Original Certification Date
- 2022
Links
Get In Touch
Contacts
Yale School of Medicine
333 Cedar St, Dept of Anesthesiology
New Haven, CT 06510
United States
Locations
Brady Memorial Laboratory
Lab
310 Cedar Street, Fl 4, Rm 419
New Haven, CT 06510
Patient Care Locations
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