Guangyu Tong, PhD
Assistant Professor of Cardiovascular Medicine and Assistant Professor of BiostatisticsDownloadHi-Res Photo
Cards
Appointments
Cardiovascular Medicine
Primary
Biostatistics
Secondary
Additional Titles
Director, Cardiovascular Medicine Analytics Center (CMAC)
Contact Info
Yale University
135 College St, Room 234
New Haven, CT 06510
United States
Appointments
Cardiovascular Medicine
Primary
Biostatistics
Secondary
Additional Titles
Director, Cardiovascular Medicine Analytics Center (CMAC)
Contact Info
Yale University
135 College St, Room 234
New Haven, CT 06510
United States
Appointments
Cardiovascular Medicine
Primary
Biostatistics
Secondary
Additional Titles
Director, Cardiovascular Medicine Analytics Center (CMAC)
Contact Info
Yale University
135 College St, Room 234
New Haven, CT 06510
United States
About
Titles
Assistant Professor of Cardiovascular Medicine and Assistant Professor of Biostatistics
Director, Cardiovascular Medicine Analytics Center (CMAC)
Biography
Dr. Guangyu Tong is the director of the Cardiovascular Medicine Analytics Center (CMAC), which provides statistical analytical support within the Section of Cardiovascular Medicine. He is an associate faculty member at the Center for Methods of Implementation and Prevention Science (CMIPS). He is an experienced biostatistician specializing in both clinical trials and observational studies. His methodological research focuses on pragmatic trial design and analysis, implementation science methods, causal inference, Bayesian statistics, missing data, and meta-analysis. His empirical research spans cardiovascular medicine, gun violence, mental health, crime and delinquency, substance use disorders, genetic determinants of health, and the well-being of immigrants and minorities.
Appointments
Cardiovascular Medicine
Assistant ProfessorPrimaryBiostatistics
Assistant ProfessorSecondary
Other Departments & Organizations
Education & Training
- PhD
- Duke University (2020)
- MA
- Columbia University (2014)
- AB
- Peking University (2012)
Research
Overview
Medical Research Interests
Cardiology; Causality; Gun Violence; Meta-Analysis; Propensity Score; Randomized Controlled Trial
Public Health Interests
Randomized Trials; Bayesian Statistics; Mental Health; Cardiovascular Diseases; Clinical Trials; Health Equity, Disparities, Social Determinants and Justice; Implementation Science
ORCID
0000-0002-7697-5029
Research at a Glance
Yale Co-Authors
Frequent collaborators of Guangyu Tong's published research.
Publications Timeline
A big-picture view of Guangyu Tong's research output by year.
Research Interests
Research topics Guangyu Tong is interested in exploring.
Fan Li, PhD
Jiaqi Tong
Kendra Plourde, PhD
Can Meng, MS, MPH
Denise Esserman, PhD
James Dziura, MPH, PhD
50Publications
414Citations
Publications
2025
Medical therapy and outcomes in REVIVED-BCIS2 and STICHES: an individual patient data analysis
Ryan M, Petrie M, Kontopantelis E, Dodd M, Tong G, Marquis-Gravel G, Docherty K, Clayton T, Lansky A, Mamas M, Rouleau J, Velazquez E, Perera D. Medical therapy and outcomes in REVIVED-BCIS2 and STICHES: an individual patient data analysis. European Heart Journal 2025, ehaf080. PMID: 40048661, DOI: 10.1093/eurheartj/ehaf080.Peer-Reviewed Original ResearchCitationsAltmetricConceptsCoronary artery bypass graftingPercutaneous coronary interventionMedical therapyPrimary outcome eventFollow-upPrimary outcomePatients treated with coronary artery bypass graftingOutcome eventsIndividual patient data analysisCoronary artery bypass graft surgeryIschaemic left ventricular dysfunctionMedian follow-upMulticentre randomized trialLeft ventricular dysfunctionOutcomes of patientsBenefit of coronary artery bypass graftingCompleteness of follow-upArtery bypass graftingCoronary artery diseasePatient data analysisIschaemic cardiomyopathyVentricular dysfunctionSurgical treatmentHeart failurePooled analysisLong-term wage inequality in imperial China: From 202 BCE to 1912 CE
Wu Q, Tong G, Zhou P. Long-term wage inequality in imperial China: From 202 BCE to 1912 CE. PLOS ONE 2025, 20: e0315627. PMID: 39854490, PMCID: PMC11761105, DOI: 10.1371/journal.pone.0315627.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsWage inequalityEvolution of wage inequalityImperial ChinaPolitical mechanismsPeasant classOfficial salarySecular declining trendGovernment recordsDynastic cycleInequalityCommodity pricesAgricultural productionSalaryTechnological mechanismsPeasantsWageQing DynastyChinaDeclining trendDynastyShort-term patternsCommoditySalary ratioSalary benchmarkingLong-term
2024
Randomized in error in pragmatic clinical trials
Tong G, Coronado G, Li C, Li F. Randomized in error in pragmatic clinical trials. Contemporary Clinical Trials 2024, 148: 107764. PMID: 39603383, PMCID: PMC11752791, DOI: 10.1016/j.cct.2024.107764.Peer-Reviewed Original ResearchCitationsAltmetricConceptsPragmatic clinical trialsElectronic health record dataHealth record dataPatient-reported dataExclusion of participantsSelection biasPatients' medical recordsAverage treatment effectOutcomes of participantsUsual carePragmatic trialTreatment effectsIntervention effectsIntention-to-treatOutcomes frameworkPost-randomization exclusionsPotential outcomes frameworkRecord dataCovariate-adjusted estimatesMedical recordsParticipantsClinical trialsInterventionTrialsArm beingA review of current practice in the design and analysis of extremely small stepped-wedge cluster randomized trials
Tong G, Nevins P, Ryan M, Davis-Plourde K, Ouyang Y, Macedo J, Meng C, Wang X, Caille A, Li F, Taljaard M. A review of current practice in the design and analysis of extremely small stepped-wedge cluster randomized trials. Clinical Trials 2024, 22: 45-56. PMID: 39377196, PMCID: PMC11810615, DOI: 10.1177/17407745241276137.Peer-Reviewed Original ResearchCitationsAltmetricConceptsSmall-sample correctionsStepped-wedge cluster randomized trialCluster randomized trialSample size calculation methodGeneralized linear mixed modelsLongitudinal correlation structureSize calculation methodLinear mixed modelsPermutation testSample sizeBayesian approachRandomized trialsCorrelation structureMixed modelsBayesian analysisGeneralized estimating equationsPermutationMedian sample sizeIntervention conditionRandomization methodEquationsHIV Symptom Clusters Among Sexual Minority Men in Ghana, West Africa: A Cross-sectional Study
Akyirem S, Tong G, Aidoo-Frimpong G, Abwoye D, López D, Wilton L, Nelson L. HIV Symptom Clusters Among Sexual Minority Men in Ghana, West Africa: A Cross-sectional Study. Journal Of The Association Of Nurses In AIDS Care 2024, 36: 108-117. PMID: 39208416, DOI: 10.1097/jnc.0000000000000497.Peer-Reviewed Original ResearchConceptsSelf-concept/self-esteemSymptom clustersSexual minority menAssociated with higher distress scoresGastrointestinal symptom clusterLate HIV diagnosisHigher distress scoresSeven symptom clustersAnalyzed cross-sectional dataMinority menCross-sectional studyMultivariate linear regressionCross-sectional dataHIV symptomsDistress scoresHIV diagnosisPsychological symptomsPrevalent symptomsSymptom identificationSymptomsHIVLinear regressionClinical characteristicsNegative Life Events and Emotional Symptoms From Ages 2 to 30 Years
Copeland W, Keen R, Tong G, Shanahan L. Negative Life Events and Emotional Symptoms From Ages 2 to 30 Years. JAMA Network Open 2024, 7: e2429448. PMID: 39207754, PMCID: PMC11362870, DOI: 10.1001/jamanetworkopen.2024.29448.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCross-sectional analysisEmotional symptomsNegative life eventsAssociated with emotional symptomsLife eventsYoung adulthoodAssociated with increased mental health symptomsCohort study analyzed dataStressful eventsTraumatic eventsMental health symptomsCross-sectional associationsLongitudinal analysisAged 2Years of follow-upStudy analyzed dataDevelopmental periodIndividuals aged 2Lifetime traumatic eventsHealth symptomsMain OutcomesLate adolescenceEmotional functioningCohort studyPrimary outcomeTrends in Firearm Injury Prevention Research Funding, Clinical Trials, and Publications in the US, 1985-2022
Lin J, Chang C, McCarthy M, Baker-Butler A, Tong G, Ranney M. Trends in Firearm Injury Prevention Research Funding, Clinical Trials, and Publications in the US, 1985-2022. JAMA Surgery 2024, 159: 461-463. PMID: 38324281, PMCID: PMC10851134, DOI: 10.1001/jamasurg.2023.7461.Peer-Reviewed Original ResearchCitationsAltmetricSociodemographic correlates of late HIV diagnosis among men who have sex with men (MSM) in Ghana
Aidoo-Frimpong G, Tong G, Akyirem S, Abwoye D, Nwanaji-Enwerem U, López D, Wilton L, Nelson L. Sociodemographic correlates of late HIV diagnosis among men who have sex with men (MSM) in Ghana. AIDS Care 2024, 36: 807-815. PMID: 38460152, DOI: 10.1080/09540121.2024.2325071.Peer-Reviewed Original ResearchCitationsConceptsLate HIV diagnosisHIV diagnosisOlder age groupsFactors associated with late HIV diagnosisIncreased risk of late diagnosisAge groupsRisk of late diagnosisImprove public health outcomesBurden of HIVAge-related disparitiesSame-gender sexual contactPublic health outcomesViral load suppressionExposure to HIVMedical engagementTailored interventionsHealth outcomesSociodemographic correlatesMedical servicesTargeted interventionsGhanaian menMSMDemographic variablesIncreased riskInterventionA BAYESIAN MACHINE LEARNING APPROACH FOR ESTIMATING HETEROGENEOUS SURVIVOR CAUSAL EFFECTS: APPLICATIONS TO A CRITICAL CARE TRIAL.
Chen X, Harhay M, Tong G, Li F. A BAYESIAN MACHINE LEARNING APPROACH FOR ESTIMATING HETEROGENEOUS SURVIVOR CAUSAL EFFECTS: APPLICATIONS TO A CRITICAL CARE TRIAL. The Annals Of Applied Statistics 2024, 18: 350-374. PMID: 38455841, PMCID: PMC10919396, DOI: 10.1214/23-aoas1792.Peer-Reviewed Original ResearchCitationsAltmetricHierarchical Bayesian modeling of heterogeneous outcome variance in cluster randomized trials
Tong G, Tong J, Jiang Y, Esserman D, Harhay M, Warren J. Hierarchical Bayesian modeling of heterogeneous outcome variance in cluster randomized trials. Clinical Trials 2024, 21: 451-460. PMID: 38197388, PMCID: PMC11233424, DOI: 10.1177/17407745231222018.Peer-Reviewed Original ResearchCitations
Academic Achievements & Community Involvement
Activities
activity Journal of the American College of Cardiology
04/01/2024 - PresentJournal ServiceStatistical Editoractivity BMC Medicine
07/01/2023 - PresentJournal ServiceEditorial Board Memberactivity American Statistical Association Connecticut Chapter
07/01/2022 - PresentProfessional OrganizationsTreasureractivity JAMA Cardiology
2021 - PresentJournal ServiceRevieweractivity Global Cardiovascular Research Funders Forum
2025 - 2025Peer Review Groups and Grant Study SectionsReview Panel MemberDetailsReviewer for International Research Challenge on Women’s Cardiovascular Health.
Honors
honor Faculty Scholar
07/01/2023National AwardNational Institute of Aging IMPACT CollaboratoryDetailsUnited States
News
News
- December 11, 2024
Paradigm-shifting work brought biostatistics student to YSPH
- November 04, 2024Source: Yale Daily News
Yale experts weigh in on gun violence prevention research possibly under threat
- October 24, 2024
New Analytics Center for Cardiovascular Medicine
- July 02, 2024
Yale Faculty Members Named to JACC Editorial Board
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Contacts
Mailing Address
Yale University
135 College St, Room 234
New Haven, CT 06510
United States