Gabriele Floris
Associate Research ScientistCards
About
Research
Publications
2026
α2-Adrenergic receptor modulates 5-HT2A-mediated behavioral effects of MDMA and psilocybin in mice
Rosado A, Yu A, Yang J, Rondeau J, Floris G, Basu A, Staszko S, Dibbs M, Feng J, Li Y, Warner-Schmidt J, Kelmendi B, Krystal J, Pittenger C, Kwan A, Kaye A. α2-Adrenergic receptor modulates 5-HT2A-mediated behavioral effects of MDMA and psilocybin in mice. Molecular Psychiatry 2026, 1-12. PMID: 42414551, DOI: 10.1038/s41380-026-03713-1.Peer-Reviewed Original Research
2025
Prefrontal 5α-reductase 2 mediates male-specific acute stress response
Cadeddu R, Braccagni G, Floris G, Branca C, Corridori E, Salviati S, Sánchez P, Santovito L, Torres J, Ortega E, Pinna G, Moos P, Scheggi S, Bortolato M. Prefrontal 5α-reductase 2 mediates male-specific acute stress response. Science Advances 2025, 11: eadr0563. PMID: 39841836, PMCID: PMC11753402, DOI: 10.1126/sciadv.adr0563.Peer-Reviewed Original Research
2024
Neuroinflammatory history results in overlapping transcriptional signatures with heroin exposure in the nucleus accumbens and alters responsiveness to heroin in male rats
Floris G, Zanda M, Dabrowski K, Daws S. Neuroinflammatory history results in overlapping transcriptional signatures with heroin exposure in the nucleus accumbens and alters responsiveness to heroin in male rats. Translational Psychiatry 2024, 14: 500. PMID: 39702361, PMCID: PMC11659471, DOI: 10.1038/s41398-024-03203-4.Peer-Reviewed Original ResearchPsilocybin reduces heroin seeking behavior and modulates inflammatory gene expression in the nucleus accumbens and prefrontal cortex of male rats
Floris G, Dabrowski K, Zanda M, Daws S. Psilocybin reduces heroin seeking behavior and modulates inflammatory gene expression in the nucleus accumbens and prefrontal cortex of male rats. Molecular Psychiatry 2024, 30: 1801-1816. PMID: 39433903, PMCID: PMC12015112, DOI: 10.1038/s41380-024-02788-y.Peer-Reviewed Original Research“Weeding out” violence? Translational perspectives on the neuropsychobiological links between cannabis and aggression
Bortolato M, Braccagni G, Pederson C, Floris G, Fite P. “Weeding out” violence? Translational perspectives on the neuropsychobiological links between cannabis and aggression. Aggression And Violent Behavior 2024, 78: 101948. PMID: 38828012, PMCID: PMC11141739, DOI: 10.1016/j.avb.2024.101948.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsThe sinking platform test: a novel paradigm to measure persistence in animal models
Floris G, Godar S, Braccagni G, Piras I, Ravens A, Zanda M, Huentelman M, Bortolato M. The sinking platform test: a novel paradigm to measure persistence in animal models. Neuropsychopharmacology 2024, 49: 1373-1382. PMID: 38396257, PMCID: PMC11251282, DOI: 10.1038/s41386-024-01827-0.Peer-Reviewed Original Research
2023
Orbitofrontal intronic circular RNA from Nrxn3 mediates reward learning and motivation for reward
Dabrowski K, Floris G, Gillespie A, Daws S. Orbitofrontal intronic circular RNA from Nrxn3 mediates reward learning and motivation for reward. Progress In Neurobiology 2023, 232: 102546. PMID: 38036039, PMCID: PMC10843848, DOI: 10.1016/j.pneurobio.2023.102546.Peer-Reviewed Original ResearchOrbitofrontal cortex microRNAs support long-lasting heroin seeking behavior in male rats
Zanda M, Floris G, Daws S. Orbitofrontal cortex microRNAs support long-lasting heroin seeking behavior in male rats. Translational Psychiatry 2023, 13: 117. PMID: 37031193, PMCID: PMC10082780, DOI: 10.1038/s41398-023-02423-4.Peer-Reviewed Original Research
2022
Increased Voluntary Alcohol Consumption in Mice Lacking GABAB(1) Is Associated With Functional Changes in Hippocampal GABAA Receptors
Floris G, Asuni G, Talani G, Biggio F, Pisu M, Zanda M, Contu L, Maciocco E, Serra M, Follesa P. Increased Voluntary Alcohol Consumption in Mice Lacking GABAB(1) Is Associated With Functional Changes in Hippocampal GABAA Receptors. Frontiers In Behavioral Neuroscience 2022, 16: 893835. PMID: 35755407, PMCID: PMC9218813, DOI: 10.3389/fnbeh.2022.893835.Peer-Reviewed Original ResearchThe steroidogenic inhibitor finasteride reverses pramipexole-induced alterations in probability discounting
Floris G, Scheggi S, Pes R, Bortolato M. The steroidogenic inhibitor finasteride reverses pramipexole-induced alterations in probability discounting. Brain Research Bulletin 2022, 181: 157-166. PMID: 35122898, PMCID: PMC9012661, DOI: 10.1016/j.brainresbull.2022.01.020.Peer-Reviewed Original Research
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