Donald Lannin, MD
Professor Emeritus of Surgery (Oncology)DownloadHi-Res Photo
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Professor Emeritus of Surgery (Oncology)
Biography
Dr. Lannin graduated from the University of Minnesota where he also completed his General Surgery residency and went on to do a fellowship in oncology funded by the National Institutes of Health. He rose through the ranks to Professor of Surgery at East Carolina University and joined the faculty at Yale in 2002. With nearly 30 years of experience in surgery, he has been instrumental in building The Breast Center -- Smilow Cancer Hospital at Yale-New Haven, serving as its Executive Director from 2002 to 2010.
Last Updated on May 26, 2024.
Departments & Organizations
Education & Training
- Resident
- University of Minnesota Minneapolis, MN (1982)
- Fellow
- National Institutes of Health (1980)
- Intern
- University of Minnesota Minneapolis, MN (1975)
- MD
- University of Minnesota (1974)
- BA
- Stanford University (1970)
Research
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Overview
Medical Research Interests
Breast Diseases; Breast Neoplasms; Surgical Oncology
ORCID
0000-0001-8700-7675
Research at a Glance
Yale Co-Authors
Frequent collaborators of Donald Lannin's published research.
Publications Timeline
A big-picture view of Donald Lannin's research output by year.
Research Interests
Research topics Donald Lannin is interested in exploring.
Anees Chagpar, MD, MBA, MPH, FACS, FRCS(C)
David Rimm, MD, PhD
Elizabeth Berger, MD, MS, FACS
Erin Hofstatter, MD
Gregory Zanieski, MD, FACS
Lajos Pusztai, MD, DPhil
32Publications
2,029Citations
Breast Neoplasms
Breast Diseases
Publications
2022
AMACR Expression is a Potential Diagnostic Marker in Apocrine Lesions of Breast, and is Associated with High Histologic Grade and Lymph Node Metastases in Some Invasive Apocrine Breast Cancers
Lerner G, Tang H, Singh K, Golestani R, St Claire S, Humphrey P, Lannin D, Janostiak R, Harigopal M. AMACR Expression is a Potential Diagnostic Marker in Apocrine Lesions of Breast, and is Associated with High Histologic Grade and Lymph Node Metastases in Some Invasive Apocrine Breast Cancers. Clinical Breast Cancer 2022, 23: 199-210. PMID: 36577560, DOI: 10.1016/j.clbc.2022.11.012.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsInvasive ductal carcinomaTriple-negative breast cancerHigh histologic gradeApocrine differentiationAMACR expressionEstrogen receptorApocrine DCISER-/PRHistologic gradeProgesterone receptorApocrine featuresBreast cancerHuman epidermal growth factor 2 (HER2) statusLack of ERDistant metastasis-free survivalDiagnostic markerInitial N stageLack estrogen receptorApocrine breast cancerLymph node metastasisNegative breast cancerAndrogen receptor mRNACoA racemase expressionBenign breast tissueBreast cancer cohortBreast Cancer Screening: Is There Room for De-escalation?
Kim L, Lannin D. Breast Cancer Screening: Is There Room for De-escalation? Current Breast Cancer Reports 2022, 14: 153-161. PMID: 36404936, PMCID: PMC9640864, DOI: 10.1007/s12609-022-00465-z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricASO Visual Abstract: Association of Medicaid Expansion on Postmastectomy Reconstruction Rates
Le Blanc J, Golshan M, Lannin D, Greenup R, Berger E, Saridakis A, Horowitz N, Zanieski G, Avraham T, Mastrioanni M, Park T. ASO Visual Abstract: Association of Medicaid Expansion on Postmastectomy Reconstruction Rates. Annals Of Surgical Oncology 2022, 29: 2191-2192. DOI: 10.1245/s10434-021-10944-9.Peer-Reviewed Original ResearchThe Effect of Black Cohosh on Ki67 expression and Tumor Volume: A Pilot Study of Ductal Carcinoma in Situ Patients
Trant A, Chagpar A, Wei W, Neumeister V, Rimm D, Stavris K, Lurie B, Frederick C, Andrejeva L, Raghu M, Killelea B, Horowitz N, Lannin D, Knill-Selby E, Sturrock T, Hofstatter E. The Effect of Black Cohosh on Ki67 expression and Tumor Volume: A Pilot Study of Ductal Carcinoma in Situ Patients. Integrative Cancer Therapies 2022, 21: 15347354221137290. PMID: 36444764, PMCID: PMC9716631, DOI: 10.1177/15347354221137290.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsTumor volumeBlack cohoshSitu patientsDuctal carcinomaAnti-inflammatory effectsTumor cellular proliferationBreast cancer treatmentCellular proliferationWilcoxon signed-rank testDCIS patientsAdverse eventsEligible subjectsWindow trialsCore biopsyInvasive diseaseKi67 expressionSigned-rank testBreast cancerGrade 3Hormone changesPatientsQuantitative immunofluorescenceBC extractSignificant toxicityCancer treatment
2017
Association of LN Evaluation with Survival in Women Aged 70 Years or Older With Clinically Node-Negative Hormone Receptor Positive Breast Cancer
Chagpar AB, Hatzis C, Pusztai L, DiGiovanna MP, Moran M, Mougalian S, Sanft T, Evans S, Hofstatter E, Wilson LD, Lannin DR. Association of LN Evaluation with Survival in Women Aged 70 Years or Older With Clinically Node-Negative Hormone Receptor Positive Breast Cancer. Annals Of Surgical Oncology 2017, 24: 3073-3081. PMID: 28766195, DOI: 10.1245/s10434-017-5936-x.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsBreast cancer-specific survivalLN evaluationPositive breast cancerOverall survivalBreast cancerHormone receptor-positive breast cancerWomen Aged 70 YearsReceptor-positive breast cancerLymph node evaluationCancer-specific survivalLower hazard rateLN surgeryBetter OSPatient ageSEER databasePatient selectionTumor characteristicsSEER dataPatientsNode evaluationHormone receptorsCancerSurvivalTreatment variablesNCDBRegional variation in breast cancer surgery: Results from the National Cancer Database (NCDB)
Chiu AS, Thomas P, Killelea BK, Horowitz N, Chagpar AB, Lannin DR. Regional variation in breast cancer surgery: Results from the National Cancer Database (NCDB). The American Journal Of Surgery 2017, 214: 907-913. PMID: 28736057, DOI: 10.1016/j.amjsurg.2017.07.008.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsAre Small Breast Cancers Good because They Are Small or Small because They Are Good?
Lannin DR, Wang S. Are Small Breast Cancers Good because They Are Small or Small because They Are Good? The New England Journal Of Medicine 2017, 376: 2286-91. PMID: 28591529, DOI: 10.1056/nejmsr1613680.Peer-Reviewed Original ResearchCitationsAltmetricIntraoperative Injection of Technetium‐99m Sulfur Colloid for Sentinel Lymph Node Biopsy in Breast Cancer Patients: A Single Institution Experience
Berrocal J, Saperstein L, Grube B, Horowitz NR, Chagpar AB, Killelea BK, Lannin DR. Intraoperative Injection of Technetium‐99m Sulfur Colloid for Sentinel Lymph Node Biopsy in Breast Cancer Patients: A Single Institution Experience. Surgery Research And Practice 2017, 2017: 5924802. PMID: 28492062, PMCID: PMC5406738, DOI: 10.1155/2017/5924802.Peer-Reviewed Original ResearchCitationsAltmetricConceptsNonsentinel lymph nodesLymph nodesSentinel lymph nodesIntraoperative injectionSulfur colloidNode biopsySentinel lymphSentinel nodesAdditional positive nonsentinel lymph nodesPositive nonsentinel lymph nodesPositive sentinel lymph nodesSentinel lymph node biopsyLymph node biopsySentinel node biopsySingle institution experienceBreast cancer patientsLong-term resultsAxillary dissectionInstitution experienceMetastatic carcinomaCancer patientsBreast centerMedian numberPatientsBiopsy
2016
Characteristics and treatment of human epidermal growth factor receptor 2 positive breast cancer: 43,485 cases from the National Cancer Database treated in 2010 and 2011
Killelea BK, Chagpar AB, Horowitz NR, Lannin DR. Characteristics and treatment of human epidermal growth factor receptor 2 positive breast cancer: 43,485 cases from the National Cancer Database treated in 2010 and 2011. The American Journal Of Surgery 2016, 213: 426-432. PMID: 27769548, DOI: 10.1016/j.amjsurg.2016.05.018.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAdenocarcinomaAdultAgedBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, LobularChemotherapy, AdjuvantDatabases, FactualFemaleHumansIncidenceInflammatory Breast NeoplasmsLymphatic MetastasisMaleMastectomyMastectomy, SegmentalMiddle AgedNeoplasm InvasivenessPaget's Disease, MammaryRacial GroupsReceptor, ErbB-2United StatesConceptsHER2-positive tumorsHuman epidermal growth factor receptor-2-positive breast cancerNational Cancer DatabasePositive breast cancerPositive tumorsBreast cancerCancer DatabaseHER2-negative tumorsInvasive breast cancerAmerican Cancer SocietyAsian/Pacific IslandersNon-Hispanic whitesBreast preservationPositive nodesHER2 positivityLymphovascular invasionNegative tumorsTumor sizeHER2 statusTreatment characteristicsCancer casesCancer SocietyAmerican CollegeTumorsYoung women
2013
Triple-negative breast cancer: molecular characterization and targeted therapies
Nicholson A, Bishop J, Lannin D, Killelea B, Guo X, Cha C, Dixon J. Triple-negative breast cancer: molecular characterization and targeted therapies. Breast Cancer Management 2013, 2: 417-430. DOI: 10.2217/bmt.13.40.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsConceptsBreast cancerTriple-negative breast cancerAggressive breast cancerCancer Genome Atlas NetworkAggressive subtypeSingle therapyClinical trialsTherapeutic targetExtensive molecular characterizationMolecular alterationsIndividual cancersCancerTherapyMolecular targetsMolecular reviewMolecular characterizationRelated mutationsSubtypesTrials
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