Daniel Chamié, MD, PhD
Assistant Professor of Medicine (Cardiovascular Medicine)Cards
About
Research
Publications
2026
Artificial intelligence-based coronary computed tomography angiography quantification of atherosclerosis burden: comparison with intravascular ultrasound in the INVICTUS Registry
Nakanishi R, Okubo R, Matsuo H, Sobue Y, Kaneko U, Sato H, Fujimoto S, Nozaki Y, Kajiya T, Miyoshi T, Ichikawa K, Abe M, Kitagawa T, Ikenaga H, Osawa K, Saji M, Iguchi N, Nakazawa G, Takahashi K, Ijichi T, Mikamo H, Kurata A, Moroi M, Iijima R, Bandeira D, Demuyakor A, Parise H, Malkasian S, Mintz G, Lansky A, Earls J, Chamié D. Artificial intelligence-based coronary computed tomography angiography quantification of atherosclerosis burden: comparison with intravascular ultrasound in the INVICTUS Registry. European Radiology 2026, 1-14. PMID: 41781729, DOI: 10.1007/s00330-026-12412-y.Peer-Reviewed Original ResearchCoronary CT angiographyLow-attenuation plaqueIntravascular ultrasoundExternal elastic membranePlaque volumeImage processing timeCalcium indexElastic membraneAtherosclerosis burdenNon-calcifiedCoronary segmentsProcessing timeExternal elastic membrane volumeCoronary Computed Tomography AngiographyPredictor of cardiovascular eventsModality findingsNon-diseased segmentsTherapeutic decision-makingRoutine clinical practiceDisease severity spectrumLumen area stenosisPlaque segmentationInter-observer variabilityCardiovascular risk assessmentMinimum lumen areaAbluminus DES+ sirolimus-eluting stent versus everolimus-eluting stent in patients with diabetes and coronary artery disease (ABILITY Diabetes Global): results from a multicentre, randomised controlled trial
Abizaid A, Mehran R, Oliva A, Chamié D, Staico R, Malik F, Vink M, Kurniadi A, Cao D, Capranzano P, Faurie B, Garot P, Hildick-Smith D, Ielasi A, Löffelhardt N, Kedev S, Mylotte D, Milewski K, Paradies V, Schmitz T, Teeuwen K, Testa L, Toelg R, Vochelet F, Vogel B, Wykrzykowska J, Sartori S, Colombo A, Saito S, Morice M, investigators A, Abizaid A, Mehran R, Oliva A, Chamié D, Staico R, Malik F, Vink M, Ahmad W, Allali A, Bouisset F, Cao D, Canville A, Capranzano P, de Winter R, De Rosa S, Faurie B, Forys J, Garot P, Hildick-Smith D, Hovasse T, Ielasi A, Indolfi C, Kedev S, Kośmider M, Kurniadi A, Löffelhardt N, Lhermusier T, Milewski K, Mylotte D, Oemwrasingh R, O'Kane P, Paradies V, Pedrazzini G, Quadri G, Sbarzaglia P, Schofer J, Schmitz T, Skurk C, Teeuwen K, Testa L, Toelg R, Toth G, Vochelet F, Varenne O, Vogel B, Witzenbichler B, Wykrzykowska J, Zurakowski A, Sartori S, Colombo A, Saito S, Morice M. Abluminus DES+ sirolimus-eluting stent versus everolimus-eluting stent in patients with diabetes and coronary artery disease (ABILITY Diabetes Global): results from a multicentre, randomised controlled trial. The Lancet 2026, 407: 227-236. PMID: 41520674, DOI: 10.1016/s0140-6736(25)02157-9.Peer-Reviewed Original ResearchConceptsRandomised controlled trialsPercutaneous coronary interventionSirolimus-eluting stentsXience everolimus-eluting stentControlled TrialsEverolimus-eluting stentFollow-up to deathTarget-lesion revascularisationTarget vessel myocardial infarctionCoronary artery diseaseFollow-upAbsolute risk differenceTarget lesion failureNon-inferiorityCardiovascular deathCox proportional hazards modelsIntention-to-treat analysisProportional hazards modelMyocardial infarctionSES groupCoronary syndromeArtery diseaseNon-ST-elevation acute coronary syndromeType 2 diabetesTime-to-event analysis
2025
Microbubble Contrast Agent Use During Invasive Coronary Microvascular Assessment
Bahl R, Mehta S, Seligman H, Rajkumar C, Gafore S, Sen S, Nijjer S, Al-Lamee R, Chamié D, Bandeira D, Zhou X, Shin M, Tang M, Petraco R. Microbubble Contrast Agent Use During Invasive Coronary Microvascular Assessment. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 103857. PMID: 41268079, PMCID: PMC12629735, DOI: 10.1016/j.jscai.2025.103857.Peer-Reviewed Original ResearchSignal-to-noise ratioSignal qualityCoronary flow reserveDoppler signal qualityUltrasound microbubble contrast agentFlow velocityDoppler-derived coronary flow reserveAssessment of coronary flow velocityMicrovascular assessmentMicrobubble contrast agentsAdministration of SonoVueContrast agent useMicrovascular function assessmentCoronary flow velocityCFR measurementsContrast agentsDoppler signalsAgent useMicrobubble contrastFlow reserveThe Lancet Commission on rethinking coronary artery disease: moving from ischaemia to atheroma
Zaman S, Wasfy J, Kapil V, Ziaeian B, Parsonage W, Sriswasdi S, Chico T, Capodanno D, Colleran R, Sutton N, Song L, Karam N, Sofat R, Fraccaro C, Chamié D, Alasnag M, Warisawa T, Gonzalo N, Jomaa W, Mehta S, Cook E, Sundström J, Nicholls S, Shaw L, Patel M, Al-Lamee R. The Lancet Commission on rethinking coronary artery disease: moving from ischaemia to atheroma. The Lancet 2025, 405: 1264-1312. PMID: 40179933, PMCID: PMC12315672, DOI: 10.1016/s0140-6736(25)00055-8.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCan AI Capture and Quantify Clinical Expertise? Implications for Intracoronary Imaging in Percutaneous Coronary Intervention
Petraco R, Bahl R, Almeida G, Bandeira D, Seligman H, Alloula A, Demuyakor A, Lansky A, Johnson T, Francis D, Mintz G, Shun-Shin M, Chamié D. Can AI Capture and Quantify Clinical Expertise? Implications for Intracoronary Imaging in Percutaneous Coronary Intervention. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 102523. PMID: 40230670, PMCID: PMC11993851, DOI: 10.1016/j.jscai.2024.102523.Peer-Reviewed Original ResearchHigh-Frequency Optical Coherence Tomography: Addressing Common Pitfalls of Traditional Optical Coherence Tomography Imaging
Case B, Wallace R, Chamié D. High-Frequency Optical Coherence Tomography: Addressing Common Pitfalls of Traditional Optical Coherence Tomography Imaging. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 102621. PMID: 40231051, PMCID: PMC11993861, DOI: 10.1016/j.jscai.2025.102621.Commentaries, Editorials and LettersSailing in Dark Waters: The Challenging Management of Recurrent In-Stent Calcified Nodule Protrusion
Bandeira D, Pfau S, Chamié D. Sailing in Dark Waters: The Challenging Management of Recurrent In-Stent Calcified Nodule Protrusion. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 102457. PMID: 40109703, PMCID: PMC11916722, DOI: 10.1016/j.jscai.2024.102457.Peer-Reviewed Original Research
2024
Can Contrast Injections Cause or Propagate Coronary Injuries? Insights From Vessel and Guiding Catheter Hemodynamics
Chamié D, Bahl R, Maia J, Echavarria-Pinto M, Gafore S, Saleh A, Cristea E, Seligman H, Joaquim R, Feres F, Sen S, Al-Lamee R, Centemero M, Baker C, Johnson T, Shun-Shin M, Lansky A, Petraco R. Can Contrast Injections Cause or Propagate Coronary Injuries? Insights From Vessel and Guiding Catheter Hemodynamics. Journal Of The Society For Cardiovascular Angiography & Interventions 2024, 3: 102396. PMID: 39807240, PMCID: PMC11725123, DOI: 10.1016/j.jscai.2024.102396.Peer-Reviewed Original ResearchFollowing the Dynamic Changes of Coronary Atherosclerosis: An Uphill Battle.
Chamié D, Pfau S. Following the Dynamic Changes of Coronary Atherosclerosis: An Uphill Battle. Journal Of The American Heart Association 2024, 13: e037395. PMID: 39435716, PMCID: PMC11935670, DOI: 10.1161/jaha.124.037395.Commentaries, Editorials and LettersIntravascular imaging-guided vs. angiography-guided percutaneous coronary intervention: A systematic review and meta-analysis of randomized controlled trials in high-risk patients and complex coronary anatomies
Teixeira L, Ferreira R, Navalha D, Pasqualotto E, Fae I, Gibicoski T, Chavez M, Talavera A, Athayde G, Chamie D. Intravascular imaging-guided vs. angiography-guided percutaneous coronary intervention: A systematic review and meta-analysis of randomized controlled trials in high-risk patients and complex coronary anatomies. International Journal Of Cardiology 2024, 416: 132510. PMID: 39222885, DOI: 10.1016/j.ijcard.2024.132510.Peer-Reviewed Original ResearchConceptsHigh-risk patientsPercutaneous coronary interventionMeta-analysis of randomized controlled trialsRandomized Controlled TrialsTarget vessel failureComplex coronary anatomyCoronary anatomyComplex lesionsRisk ratioCardiovascular mortalityStent thrombosisMyocardial infarctionControlled TrialsAngiography-guided percutaneous coronary interventionProcedure-related complicationsMeta-analysisRisk of MACEAdverse cardiac eventsConfidence intervalsSystematic reviewIntravascular imagingRandom-effects modelNo significant differenceCardiac eventsPrimary outcome
Academic Achievements & Community Involvement
News
News
- December 09, 2025
Building a Career in Cutting-Edge Intravascular Imaging
- October 28, 2025Source: JSCAI: Conversations in Interventional Cardiology
Coronary Compliance Modification by Intravascular Lithotripsy: New Predictor of Stent Expansion in Calcified Coronary Lesions
- October 21, 2025Source: JSCAI: Conversations in Interventional Cardiology
High-Definition Intravascular Ultrasound Versus Optical Coherence Tomography: Lumen Size and Plaque Morphology
- August 07, 2025Source: Clinical Trial Results
Dr. Daniel Chamie and Dr. C. Michael Gibson discuss: Clinical Utility of Atherosclerosis Imaging: Lessons Learned from Intravascular Ultrasound
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Mailing Address
Yale School of Medicine
135 College Street
New Haven, Connecticut 06510
United States