Carolina Gomis Perez, PhD
Associate Research ScientistDownloadHi-Res Photo
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Contact Info
Cellular & Molecular Physiology
Nanobiology Institute , 850 West Campus Drive ISTC 220B
West Haven, CT 06516
United States
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Titles
Associate Research Scientist
Appointments
Cellular & Molecular Physiology
Associate Research ScientistPrimary
Other Departments & Organizations
Education & Training
- PhD
- University of Siena, Cellular Physiology (2009)
- MSc
- University of Murcia, Biology and Reproductive Technology (2005)
- BS
- University of Miguel Hernandez, Biochemistry (2004)
Research
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Overview
Medical Research Interests
B-Lymphocytes; Biophysics; Cell Membrane; Electrophysiology; Endocytosis; Exocytosis; Liposomes; Membrane Lipids; Optical Tweezers; Physiology
ORCID
0000-0002-6818-4403- View Lab Website
Karatekin Lab
Research at a Glance
Yale Co-Authors
Frequent collaborators of Carolina Gomis Perez's published research.
Publications Timeline
A big-picture view of Carolina Gomis Perez's research output by year.
Research Interests
Research topics Carolina Gomis Perez is interested in exploring.
Ane Landajuela Larma
Erdem Karatekin, PhD
Stephen Waxman, MD, PhD
Sulayman Dib-Hajj, PhD
Benjamin Machta, PhD
Betsy Schulman, PhD
25Publications
725Citations
Cell Membrane
Electrophysiology
Publications
2026
Friction-driven scission: How nonlocal mechanisms contribute to membrane fission across domains of life
Landajuela A, Perez C, Bassereau P, Callan-Jones A, Karatekin E. Friction-driven scission: How nonlocal mechanisms contribute to membrane fission across domains of life. Science Advances 2026, 12: eadz7607. PMID: 41499510, PMCID: PMC12778047, DOI: 10.1126/sciadv.adz7607.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAltmetricMeSH Keywords
2024
Cell Membrane Tension Gradients, Membrane Flows, and Cellular Processes
Yan Q, Gomis Perez C, Karatekin E. Cell Membrane Tension Gradients, Membrane Flows, and Cellular Processes. Physiology 2024, 39: 231-245. PMID: 38501962, PMCID: PMC11368524, DOI: 10.1152/physiol.00007.2024.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricNav1.8 in small dorsal root ganglion neurons contributes to vincristine-induced mechanical allodynia
Nascimento de Lima A, Zhang H, Chen L, Effraim P, Gomis-Perez C, Cheng X, Huang J, Waxman S, Dib-Hajj S. Nav1.8 in small dorsal root ganglion neurons contributes to vincristine-induced mechanical allodynia. Brain 2024, 147: 3157-3170. PMID: 38447953, DOI: 10.1093/brain/awae071.Peer-Reviewed Original ResearchCitations
2022
Membrane fission during bacterial spore development requires cellular inflation driven by DNA translocation
Landajuela A, Braun M, Martínez-Calvo A, Rodrigues CDA, Gomis Perez C, Doan T, Rudner DZ, Wingreen NS, Karatekin E. Membrane fission during bacterial spore development requires cellular inflation driven by DNA translocation. Current Biology 2022, 32: 4186-4200.e8. PMID: 36041438, PMCID: PMC9730832, DOI: 10.1016/j.cub.2022.08.014.Peer-Reviewed Original ResearchCitationsAltmetricRapid propagation of membrane tension at retinal bipolar neuron presynaptic terminals
Perez C, Dudzinski NR, Rouches M, Landajuela A, Machta B, Zenisek D, Karatekin E. Rapid propagation of membrane tension at retinal bipolar neuron presynaptic terminals. Science Advances 2022, 8: eabl4411. PMID: 34985955, PMCID: PMC11580022, DOI: 10.1126/sciadv.abl4411.Peer-Reviewed Original ResearchCitationsAltmetric
2021
An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel
Urrutia J, Aguado A, Gomis-Perez C, Muguruza-Montero A, Ballesteros OR, Zhang J, Nuñez E, Malo C, Chung HJ, Leonardo A, Bergara A, Villarroel A. An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel. BMC Biology 2021, 19: 109. PMID: 34020651, PMCID: PMC8138981, DOI: 10.1186/s12915-021-01040-1.Peer-Reviewed Original ResearchCitations
2020
A 49-residue sequence motif in the C terminus of Nav1.9 regulates trafficking of the channel to the plasma membrane
Sizova D, Huang J, Akin E, Estacion M, Gomis-Perez C, Waxman S, Dib-Hajj S. A 49-residue sequence motif in the C terminus of Nav1.9 regulates trafficking of the channel to the plasma membrane. Journal Of Biological Chemistry 2020, 295: 1077-1090. DOI: 10.1016/s0021-9258(17)49917-0.Peer-Reviewed Original ResearchCitations
2018
Homomeric Kv7.2 current suppression is a common feature in KCNQ2 epileptic encephalopathy
Gomis‐Pérez C, Urrutia J, Marcé‐Grau A, Malo C, López‐Laso E, Felipe‐Rucián A, Raspall‐Chaure M, Macaya A, Villarroel A. Homomeric Kv7.2 current suppression is a common feature in KCNQ2 epileptic encephalopathy. Epilepsia 2018, 60: 139-148. PMID: 30478917, DOI: 10.1111/epi.14609.Peer-Reviewed Original ResearchCitationsAltmetricResilience to Pain: A Peripheral Component Identified Using Induced Pluripotent Stem Cells and Dynamic Clamp
Mis MA, Yang Y, Tanaka BS, Gomis-Perez C, Liu S, Dib-Hajj F, Adi T, Garcia-Milian R, Schulman BR, Dib-Hajj SD, Waxman SG. Resilience to Pain: A Peripheral Component Identified Using Induced Pluripotent Stem Cells and Dynamic Clamp. Journal Of Neuroscience 2018, 39: 382-392. PMID: 30459225, PMCID: PMC6335750, DOI: 10.1523/jneurosci.2433-18.2018.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsAdultChildChronic PainErythromelalgiaExcitatory Postsynaptic PotentialsExomeFemaleGanglia, SpinalHumansImmunohistochemistryIndividualityInduced Pluripotent Stem CellsKCNQ Potassium ChannelsMaleMembrane PotentialsNAV1.7 Voltage-Gated Sodium ChannelPain MeasurementPatch-Clamp TechniquesResilience, PsychologicalSensory Receptor CellsStructural basis and energy landscape for the Ca2+ gating and calmodulation of the Kv7.2 K+ channel
Bernardo-Seisdedos G, Nuñez E, Gomis-Perez C, Malo C, Villarroel Á, Millet O. Structural basis and energy landscape for the Ca2+ gating and calmodulation of the Kv7.2 K+ channel. Proceedings Of The National Academy Of Sciences Of The United States Of America 2018, 115: 2395-2400. PMID: 29463698, PMCID: PMC5873240, DOI: 10.1073/pnas.1800235115.Peer-Reviewed Original ResearchCitationsAltmetric
Academic Achievements & Community Involvement
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Honors
honor Pilot Award : “Membrane Mechanobiology in Alzheimer’s Disease”
04/30/2027, 05/01/2026Yale School of Medicine AwardAlzheimer's Disease Research Center (ADRC)DetailsUnited States
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Mailing Address
Cellular & Molecular Physiology
Nanobiology Institute , 850 West Campus Drive ISTC 220B
West Haven, CT 06516
United States