Aurobind Vidyarthi, PhD
Associate Research Scientist (Rheumatology, Allergy & Immunology)DownloadHi-Res Photo
Cards
Appointments
Rheumatology
Primary
About
Titles
Associate Research Scientist (Rheumatology, Allergy & Immunology)
Appointments
Rheumatology
Associate Research ScientistPrimary
Other Departments & Organizations
Education & Training
- PhD
- CSIR - Institute of Microbial Technology, Jawaharlal Nehru University (2016)
- MSc
- Panjab University (2009)
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Aurobind Vidyarthi's published research.
Joseph Craft, MD
Bony De Kumar, PhD
Carla Rothlin, PhD
Neima Briggs, MD, PhD
Sourav Ghosh, PhD
Yong Kong, PhD
Publications
2024
The amalgam of naive CD4+ T cell transcriptional states is reconfigured by helminth infection to dampen the amplitude of the immune response
Even Z, Meli A, Tyagi A, Vidyarthi A, Briggs N, de Kouchkovsky D, Kong Y, Wang Y, Waizman D, Rice T, De Kumar B, Wang X, Palm N, Craft J, Basu M, Ghosh S, Rothlin C. The amalgam of naive CD4+ T cell transcriptional states is reconfigured by helminth infection to dampen the amplitude of the immune response. Immunity 2024, 57: 1893-1907.e6. PMID: 39096910, PMCID: PMC11421571, DOI: 10.1016/j.immuni.2024.07.006.Peer-Reviewed Original ResearchCitationsAltmetricConceptsT cell receptorImmune responseNaive CD4<sup>+</sup> T cellsCD4<sup>+</sup> T cellsIFN-IHelminth infectionsNippostrongylus brasiliensis infectionDecreased immune responseType I interferonNaive TT cellsMemory-likeUnrelated antigensTranscriptional changesExtracellular matrixSPF miceCell receptorsI interferonGerm-freeResponse to certain environmental cuesInfectionMiceFunctional changesCell transcriptional statesTranscriptional heterogeneityCBLs downregulation foretells T cell ubiquitination leading to autoimmunity
Vidyarthi A, Craft J. CBLs downregulation foretells T cell ubiquitination leading to autoimmunity. Cell Chemical Biology 2024, 31: 1239-1241. PMID: 39029453, DOI: 10.1016/j.chembiol.2024.06.010.Peer-Reviewed Original ResearchMeSH Keywords and Concepts