Anh Phu
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About
Biography
Anh was born in Vietnam and moved to San Francisco, California at the age of 11 with his family. Anh graduated from the University of California, Berkeley in 2019 majoring in Molecular and Cell Biology. He then spent the next three years working in Dr. Robert Raffai’s lab at the University of California, San Francisco studying macrophage immunometabolism and microRNAs in atherosclerosis and cardiometabolic disease. His research interests focus on investigating the mechanisms and impact of immune cell’s metabolism and inflammation on chronic inflammatory diseases. His other interests outside of the laboratory include public health projects and serving the underserved communities.
Anh finds it oddly relaxing spending time in the lab to do cell and tissue culture and take care of his experimental mice. Besides that, he enjoys being in the kitchen to cook Vietnamese dishes. In his free time, he also likes to play basketball, soccer, and badminton.
Departments & Organizations
Education & Training
- BA
- University of California, Berkeley, Molecular and Cell Biology (2019)
Research
Research at a Glance
Publications Timeline
A big-picture view of Anh Phu's research output by year.
11Publications
22Citations
Publications
Featured Publications
ApoE expression in macrophages communicates immunometabolic signaling that controls hyperlipidemia-driven hematopoiesis & inflammation via extracellular vesicles.
Phu TA, Ng M, Vu NK, Gao AS, Raffai RL. ApoE expression in macrophages communicates immunometabolic signaling that controls hyperlipidemia-driven hematopoiesis & inflammation via extracellular vesicles. J Extracell Vesicles 2023, 12: e12345. PMID: 37593979, DOI: 10.1002/jev2.12345.Peer-Reviewed Original ResearchIL-4 polarized human macrophage exosomes control cardiometabolic inflammation and diabetes in obesity.
Phu TA, Ng M, Vu NK, Bouchareychas L, Raffai RL. IL-4 polarized human macrophage exosomes control cardiometabolic inflammation and diabetes in obesity. Molecular Therapy : The Journal Of The American Society Of Gene Therapy 2022, 30: 2274-2297. PMID: 35292359, DOI: 10.1016/j.ymthe.2022.03.008.Peer-Reviewed Original ResearchApoE enhances mitochondrial metabolism via microRNA-142a/146a-regulated circuits that suppress hematopoiesis and inflammation in hyperlipidemia.
Phu TA, Vu NK, Ng M, Gao AS, Stoolman JS, Chandel NS, Raffai RL. ApoE enhances mitochondrial metabolism via microRNA-142a/146a-regulated circuits that suppress hematopoiesis and inflammation in hyperlipidemia. Cell Rep 2023, 42: 113206. PMID: 37824329, DOI: 10.1016/j.celrep.2023.113206.Peer-Reviewed Original Research
2023
Polarized macrophages regulate fibro/adipogenic progenitor (FAP) adipogenesis through exosomes.
Liu M, Ng M, Phu T, Bouchareychas L, Feeley BT, Kim HT, Raffai RL, Liu X. Polarized macrophages regulate fibro/adipogenic progenitor (FAP) adipogenesis through exosomes. Stem Cell Res Ther 2023, 14: 321. PMID: 37936229, DOI: 10.1186/s13287-023-03555-6.Peer-Reviewed Original ResearchExomap1 mouse: a transgenic model for in vivo studies of exosome biology.
Fordjour FK, Abuelreich S, Hong X, Chatterjee E, Lallai V, Ng M, Saftics A, Deng F, Carnel-Amar N, Wakimoto H, Shimizu K, Bautista M, Phu TA, Vu NK, Geiger PC, Raffai RL, Fowler CD, Das S, Christenson LK, Jovanovic-Talisman T, Gould SJ. Exomap1 mouse: a transgenic model for in vivo studies of exosome biology. BioRxiv 2023 PMID: 37398219, DOI: 10.1101/2023.05.29.542707.Peer-Reviewed Original ResearchPatients with abdominal aortic aneurysms have reduced levels of microRNA 122-5p in circulating exosomes.
Lopez JL, Ramirez JL, Phu TA, Duong P, Bouchareychas L, Kuhrau CR, Lin PY, Eckalbar WL, Barczak AJ, Rudolph JD, Maliskova L, Conte MS, Vartanian SM, Raffai RL, Oskowitz AZ. Patients with abdominal aortic aneurysms have reduced levels of microRNA 122-5p in circulating exosomes. PLoS One 2023, 18: e0281371. PMID: 36787323, DOI: 10.1371/journal.pone.0281371.Peer-Reviewed Original ResearchExomap1 mouse: A transgenic model for in vivo studies of exosome biology
Fordjour FK, Abuelreich S, Hong X, Chatterjee E, Lallai V, Ng M, Saftics A, Deng F, Carnel-Amar N, Wakimoto H, Shimizu K, Bautista M, Phu TA, Vu NK, Geiger PC, Raffai RL, Fowler CD, Das S, Christenson LK, Jovanovic-Talisman T, Gould SJ. Exomap1 mouse: a transgenic model for in vivo studies of exosome biology. Extracellular Vesicle 2023 , DOI: https://doi.org/10.1016/j.vesic.2023.100030.Peer-Reviewed Original Research
2022
Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research
Mateescu B, Jones JC, Alexander RP, Alsop E, An JY, Asghari M, Boomgarden A, Bouchareychas L, Cayota A, Chang HC, Charest A, Chiu DT, Coffey RJ, Das S, De Hoff P, deMello A, D’Souza-Schorey C, Elashoff D, Eliato KR, Franklin JL, Galas DJ, Gerstein MB, Ghiran IH, Go DB, Gould S, Grogan TR, Higginbotham JN, Hladik F, Huang TJ, Huo X, Hutchins E, Jeppesen DK, Jovanovic-Talisman T, Kim BYS, Kim S, Kim KM, Kim Y, Kitchen RR, Knouse V, LaPlante EL, Lebrilla CB, Lee LJ, Lennon KM, Li G, Li F, Li T, Liu T, Liu Z, Maddox AL, McCarthy K, Meechoovet B, Maniya N, Meng Y, Milosavljevic A, Min BH, Morey A, Ng M, Nolan J, De Oliveira G, Paulaitis ME, Phu TA, Raffai RL, Reátegui E, Roth ME, Routenberg DA, Rozowsky J, Rufo J, Senapati S, Shachar S, Sharma H, Sood AK, Stavrakis S, Stürchler A, Tewari M, Tosar JP, Tucker-Schwartz AK, Turchinovich A, Valkov N, Van Keuren-Jensen K, Vickers KC, Vojtech L, Vreeland WN, Wang C, Wang K, Wang Z, Welsh JA, Witwer KW, Wong DTW, Xia J, Xie YH, Yang K, Zaborowski MP, Zhang C, Zhang Q, Zivkovic AM, Laurent LC. Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research. IScience 2022, 25: 104653. PMID: 35958027, PMCID: PMC9358052, DOI: 10.1016/j.isci.2022.104653.Peer-Reviewed Original ResearchCitationsAltmetric
2021
Visualizing transfer of microbial biomolecules by outer membrane vesicles in microbe-host-communication in vivo.
Bittel M, Reichert P, Sarfati I, Dressel A, Leikam S, Uderhardt S, Stolzer I, Phu TA, Ng M, Vu NK, Tenzer S, Distler U, Wirtz S, Rothhammer V, Neurath MF, Raffai RL, Günther C, Momma S. Visualizing transfer of microbial biomolecules by outer membrane vesicles in microbe-host-communication in vivo. Journal Of Extracellular Vesicles 2021, 10: e12159. PMID: 34664784, PMCID: PMC8524437, DOI: 10.1002/jev2.12159.Peer-Reviewed Original ResearchHigh glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis.
Bouchareychas L, Duong P, Phu TA, Alsop E, Meechoovet B, Reiman R, Ng M, Yamamoto R, Nakauchi H, Gasper WJ, Van Keuren-Jensen K, Raffai RL. High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis. IScience 2021, 24: 102847. PMID: 34381972, PMCID: PMC8333149, DOI: 10.1016/j.isci.2021.102847.Peer-Reviewed Original Research