Alissa Chen, MD, MPH, MHS
InstructorAbout
Research
Publications
Featured Publications
Efficacy of antiobesity medications for weight reduction in older adults: a systematic review
Chen A, Hajduk A, Grimshaw A, Fried T, Jastreboff A, Lipska K. Efficacy of antiobesity medications for weight reduction in older adults: a systematic review. Obesity 2024 PMID: 39725567, PMCID: PMC12198421, DOI: 10.1002/oby.24160.Peer-Reviewed Original ResearchOlder adultsAntiobesity medicationsStudy of older adultsOlder adults ageAdult ageCardiovascular diseaseRisk of biasAdverse events associated with useWeight reductionStatistically significant weight reductionFood and Drug AdministrationClinical careSystematic reviewInclusion criteriaLimited evidenceBaseline weightPlacebo groupObservational studySeven medicationsAdverse eventsAdultsDrug AdministrationEvaluation studiesMedicationSignificant weight reductionCost-Related Prescription Drug Rationing by Adults With Obesity
Chen A, Borden C, Canavan M, Ross J, Oladele C, Lipska K. Cost-Related Prescription Drug Rationing by Adults With Obesity. JAMA Network Open 2024, 7: e2433000. PMID: 39499520, PMCID: PMC11539006, DOI: 10.1001/jamanetworkopen.2024.33000.Peer-Reviewed Original ResearchTreating Sarcopenic Obesity in the Era of Incretin Therapies: Perspectives and Challenges.
Chen A, Batsis J. Treating Sarcopenic Obesity in the Era of Incretin Therapies: Perspectives and Challenges. Diabetes 2025 PMID: 40644314, DOI: 10.2337/dbi25-0004.Peer-Reviewed Original ResearchSarcopenic obesityOlder adultsMuscle massObesity-related complicationsImproving physical functionPeople aged >Receptor agonistsImprove quality of lifeReduced skeletal muscle massIncretin therapiesLoss of muscle massAdverse eventsGLP-1RAsSkeletal muscle massPreserving muscle massQuality of lifeTreat obesity-related complicationsSignificant health challengesTreat sarcopenic obesityIncreased rate of adverse eventsGlucagon-like peptide 1 receptor agonistsPeptide 1 receptor agonistsPhysical functionMuscle mass lossLifestyle factors
2025
Proportion of Obesity-Related Conditions Attributable to Obesity in US Adolescents and Young Adults
Chetty A, Chen A, Hajduk A, Sharifi M, Nugent J. Proportion of Obesity-Related Conditions Attributable to Obesity in US Adolescents and Young Adults. American Heart Journal 2025, 290: 28-29. DOI: 10.1016/j.ahj.2025.07.065.Peer-Reviewed Original ResearchPopulation attributable fractionBody mass indexObesity-related conditionsYoung adultsUS youthNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyUS adolescentsNutrition Examination SurveyComplex survey methodsNormal body mass indexPrevalence of obesityCross-sectional studyAttributable fractionExamination SurveyNHANES cyclesInsurance statusType 2 diabetesRelative riskLiver steatosisMass indexLogistic regressionAge categoriesObesityExclusion criteriaClinical Characteristics of Adults at Risk of Medicaid Disenrollment Due to HR 1 Work Requirements.
Chetty AK, Ross JS, Chen AS. Clinical Characteristics of Adults at Risk of Medicaid Disenrollment Due to HR 1 Work Requirements. JAMA 2025 PMID: 41032309, DOI: 10.1001/jama.2025.16533.Peer-Reviewed Original ResearchProportion of Obesity-Related Conditions Attributable to Obesity and Overweight in US Youth
Chetty A, Chen A, Hajduk A, Sharifi M, Nugent J. Proportion of Obesity-Related Conditions Attributable to Obesity and Overweight in US Youth. JAMA Pediatrics 2025, 179 PMID: 40853652, PMCID: PMC12379120, DOI: 10.1001/jamapediatrics.2025.2716.Peer-Reviewed Original ResearchExclusion of Older Adults from Obesity Treatment Pivotal Trials of GLP-1RAs and GIP/GLP-1RAs
Chen A, Liang Y, Lipska K, Ross J, Ramachandran R. Exclusion of Older Adults from Obesity Treatment Pivotal Trials of GLP-1RAs and GIP/GLP-1RAs. Journal Of General Internal Medicine 2025, 1-3. PMID: 40728804, DOI: 10.1007/s11606-025-09769-z.Peer-Reviewed Original ResearchCompounded GLP-1 Receptor Agonists: Opportunity for Compassionate Conversation
Chetty A, Chen A. Compounded GLP-1 Receptor Agonists: Opportunity for Compassionate Conversation. Journal Of General Internal Medicine 2025, 1-2. PMID: 40696223, DOI: 10.1007/s11606-025-09765-3.Commentaries, Editorials and LettersPrescribing GLPs for Obesity Treatment for Adults at a University Based Health Maintenance Organization by Race, Ethnicity, and Socioeconomic Status
Chen A, Brunetto W, Canavan M, Lipska K, Richey E, Wilson M, Zarro J, Ross J. Prescribing GLPs for Obesity Treatment for Adults at a University Based Health Maintenance Organization by Race, Ethnicity, and Socioeconomic Status. Journal Of General Internal Medicine 2025, 1-7. PMID: 40588707, DOI: 10.1007/s11606-025-09691-4.Peer-Reviewed Original ResearchHealth maintenance organizationStaff-model health maintenance organizationArea Deprivation IndexBody mass indexLow socioeconomic statusSocioeconomic statusNon-Hispanic patientsPrescription receiptMaintenance organizationBlack patientsPatients of low socioeconomic statusHispanic patientsElectronic health record dataWhite patientsHealth record dataObesity treatmentDesignCross-sectional studyAssociation of raceHighest prevalencePrevalence of prescriptionsSelf-reported raceMain outcome measuresLogistic regression modelsObesity-related conditionsDeprivation index2206-LB: Weight Conversations—Examining Clinicians' Approaches to Discussing Weight during Routine Diabetes Care
DOWER J, GONZALEZ LOPEZ C, BRANDA M, CAMP A, CHEN A, MONTORI V, OCHOA-PRIETO M, LIPSKA K. 2206-LB: Weight Conversations—Examining Clinicians' Approaches to Discussing Weight during Routine Diabetes Care. Diabetes 2025, 74 DOI: 10.2337/db25-2206-lb.Peer-Reviewed Original ResearchDiabetes careClinical encountersStigmatizing languagePrimary care visitsRoutine diabetes careWeight-related conversationsPrimary careUsual careCare visitsChi-square testWeight managementLifestyle changesGLP-1 receptor agonistsType 2 diabetesMedication useCareStatistical significance of relationshipsClinician's approachWeight lossDietary changesCoding recordsWeight conversionCliniciansInterventionRoutine encounters
Clinical Care
Overview
Alissa Chen, MD, MPH, is a primary care physician and researcher who enjoys focusing on prevention.
“In medical school, I completed a master’s in public health. As I learned more about the health care system and how to help patients on a larger level, I knew that primary care was the best way to do that as a physician,” she says. “Primary care is all about prevention, which we do by screening and by treating illnesses early to prevent long-term problems.”
That, Dr. Chen says, is her favorite way to practice medicine. “I want to keep people happy and healthy for a long time as opposed to treating the downstream effects of untreated illnesses,” she says.
The best part of her job, she says, is getting to know her patients and building relationships with them. “It’s just such a beautiful thing to be a part of people’s lives,” she says.
Dr. Chen’s clinical care is largely focused on managing hypertension and diabetes. “Both of theses conditions are complicated and I enjoy dedicating time to help patients understand them,” she says. “For patients, understanding diabetes is like getting a PhD in it. There are so many things patients need to learn to manage it, like how to monitor sugar, give injections, and alter your diet. Similarly, high blood pressure may seem simple, but a deep understanding of it is important when it is an illness patients might not feel on a daily basis. I like finding ways to explain things to people in ways they can understand and partnering with them to figure out which medications work best for them.”
Dr. Chen’s research interests include health care access and affordability and obesity in older adults.
Clinical Specialties
Board Certifications
Obesity Medicine
- Certification Organization
- AB of Obesity Medicine
- Original Certification Date
- 2023
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2022
News
News
- November 11, 2025
New Study Reveals High Disease Burden Among At-Risk Medicaid Beneficiaries
- August 25, 2025
Examining the Impact of Treating and Preventing Obesity to Prevent Obesity-Related Conditions
- May 21, 2025Source: NBC CT
Connecticut Attorney General Takes Action Against Bootleg Weight Loss Drugs
- February 19, 2025
New Study Finds Online Advertising for Compounded Diabetes and Weight-Loss Drugs May Mislead Consumers