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Alan Dardik

MD/PhD, FACS, FAHA
Professor of Surgery (Vascular) and of Cellular and Molecular Physiology; Vice Chair (Faculty Affairs), Surgery

Contact Information

Alan Dardik, MD/PhD, FACS, FAHA

Patient Care Location

  • VA Connecticut Healthcare
    950 Campbell Avenue, Wing Department of Surgery, Ste Bldg 1, Room 4-220
    West Haven, CT, 06516

Lab Location

Office Location

Mailing Address

  • Dardik Lab

    Yale University School of Medicine, 10 Amistad Street; PO Box 208089

    New Haven, CT, 06520-8089

    United States

Alan Dardik
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Appointments

Biography

Dr. Alan Dardik is a surgeon-scientist who uses the power of molecular biology to achieve a modern understanding of vascular disease, using the basic science laboratory to ultimately benefit patients with vascular disease.

Dr. Dardik trained at Yale, the University of Pennsylvania, and the Johns Hopkins Hospital before his appointment to the Yale faculty in 2001. Dr. Dardik focuses his clinical practice on teaching at the VA Connecticut, where he was formerly the Chief of the Vascular Surgery.  Dr. Dardik has won the C. Elton Cahow Award for Outstanding Faculty Teaching from Yale’s Department of Surgery and the Faculty Teaching Award from St. Mary’s Hospital. Dr. Dardik is also a Vice Chair of Yale’s Department of Surgery where he is charged with Faculty Affairs, and he has served as Yale's Interim Division Chief of Vascular and Endovascular Surgery.

The Dardik laboratory studies the healing and function of blood vessels, fistulae and vessel patches that are used in patients having vascular surgery. The laboratory is trying to understand the fundamental molecular mechanisms by which vein graft adaptation and arteriovenous fistula maturation result in positive remodeling and successful adaptation to the arterial environment, yet often proceed, in the long-term, to neointimal hyperplasia and failure. The laboratory also studies novel methods to deliver stem cells to diabetic wounds. The laboratory is funded from the NIH as well as Yale's Department of Surgery.

Dr. Dardik is a past President of the International Society for Vascular Surgery, and has edited the textbook “Vascular Surgery: A Global Perspective.”

Dr. Dardik currently serves as the Editor for the newly-launched journal JVS-Vascular Science and is the President of the Association of VA Surgeons.  He has run several national and international meetings, including the Society for Vascular Surgery Vascular Research Initiatives Conference, and has served on numerous peer review committees including review for the NIH, the VA, and Vascular Cures.

Education & Training

  • MD/PhD
    University of Pennsylvania (1993)
  • BS
    Yale University, New Haven, CT, Computer Science (1986)
  • Fellow
    Vascular Surgery; The Johns Hopkins Hospital
  • Chief Resident
    General Surgery; The Johns Hopkins Hospital
  • Specialist Registrar
    The John Radcliffe Hospital, Oxford, England
  • Postdoctoral Fellow (NIH F32)
    Johns Hopkins University
  • Resident
    The Johns Hopkins Hospital

Activities

  • Invited lecture, The 3rd China Vascular Congress CVC 2018
    Beijing, China 2018
  • Keynote lecture, Frontiers of Simulation and Experimentation for Personalized Cardiovascular Management and Treatment Conference
    London, United Kingdom 2018
  • Grand Rounds Department of Surgery
    Ottawa, Canada 2018
  • Invited lecture, Chinese Chapter Congress of the International Union of Angiology, 13th annual Chinese Capital Vascular Symposium
    Beijing, China 2017
  • Keynote lecture, the 39th Annual Scientific Meeting of the Canadian Society for Vascular Surgery
    Banff, Canada 2017
    Improving the outcome of vein grafts and fistulae: Should surgeons turn veins into arteries?
  • Keynote lecture, The 2nd China Vascular Congress CVC 2017
    Beijing, China 2017
  • Invited lecture, Cambridge University, Cambridge, England
    Cambridge, United Kingdom 2016
  • Visiting Professor lecture, University of Nice, Nice, France
    Nice, France 2016
  • Keynote lecture, 16th Annual Meeting of the Tissue and Cell Engineering Society, London, UK
    London, United Kingdom 2016
    Delivery Of Mesenchymal Stem Cells In Biomimetic Engineered Scaffolds Promotes Healing Of Diabetic Ulcers
  • Invited lecture, 44th annual meeting of the Japanese Society for Vascular Surgery, Tokyo, Japan
    Tokyo, Japan 2016
    Improving the outcome of vein grafts and fistulae: Should surgeons turn veins into arteries?
  • Invited lecture, Department of Surgery, University of Tokyo, Tokyo, Japan
    Tokyo, Japan 2016
    How do veins and patches adapt to their new surgical environment?
  • Presidential Address, International Society for Vascular Surgery
    Athens, Greece 2015
  • Invited lecture, Department of Mechanical Engineering, University College of London
    London, United Kingdom 2015
    How do vascular interventions fail, and what are the opportunities?
  • Invited lectures, 9th China Southern Endovascular Congress; 6th Wang Zhong Gao Vascular Forum
    Changsha, China 2015
    1) Metabolic Syndrome Predicts High Risk Status for Vascular Surgery; 2) What is different about carotid angioplasty in elderly patients?
  • Keynote lecture, European Society for Vascular Surgery spring meeting
    Frankfurt am Main, Germany 2015
    Surgical alchemy: Do surgeons turn veins into arteries?
  • Invited Lecture, Controversies & Updates in Vascular Surgery 2014
    Paris, France 2014
    CEA: What is the current best patch if any? CEA. Quel est le meilleur patch (s’il existe) ?
  • Visiting Professor lecture, University of Milan
    Milano, Italy 2014
    Changing veins into arteries: How does Eph-B4 regulate vessel identity?
  • Faculty organizer, ISVS 2014 China meeting
    Guangzhou, China 2014
    Faculty organizer of the International Society for Vascular Surgery meeting in Guangzhou, China.
  • Invited lecture, Institute of Biomedical Engineering, University College of London
    London, United Kingdom 2014
    Hypoxia-activated mesenchymal stem cells: A novel therapy for diabetic wounds
  • President, International Society for Vascular Surgery
    United States 2014
    The mission of the International Society for Vascular Surgery is: To educate other healthcare professionals, government agencies and the general public concerning the unique services and valuable benefits provided by Vascular Surgery practitioners who are well trained and committed to the specialty in all its nuances. To identify and provide recognition to individuals who meet certain guidelines, which qualify them as, committed and accomplished vascular surgeons. To provide scholarships, travel, poster and abstract awards to fellows in training, in an effort to improve the delivery of care in their respective country.
  • Visiting Professor lecture, Surgical Grand Rounds, Royal National Orthopaedic Hospital, University College of London
    Stanmore, United Kingdom 2013
    What do animal models of ischemia teach us about therapeutic angiogenesis?
  • Visiting Professor lecture, Surgical Grand Rounds, Universidade Federal de Minas Gerais
    Belo Horizonte, Brazil 2013
    Preoperative Management of the Surgical Patient
  • Visiting Professor lecture, Department of Vascular Surgery, Hôpital St. Roch, University of Nice
    Nice, France 2013
    Changing veins into arteries: How does Eph-B4 regulate vessel identity?
  • Visiting Professor lecture, Sun-Yat Sen University School of Medicine
    Guangzhou, China 2013
    Do surgeons turn veins into arteries?
  • Invited lectures, 1st annual Chinese Chapter Congress of the International Union of Angiology
    Beijing, China 2013
    1) Advanced Age and Disease Predict Lack of Satisfaction After Iliac Stent Placement. 2) Factors for consideration for endovascular repair of aortic dissections: A Yale University perspective. 3) Current trends in the treatment of diabetic foot in America (associated Diabetic Foot Symposium).
  • Visiting Professor, XuanWu Hospital, Capital Medical University
    Beijing, China 2013
    Visiting Professor lectures, performance of surgical cases in the operating room.
  • Invited lectures, 40th annual meeting of the Japanese Society of Vascular Surgery
    Nagano-shi, Japan 2012
    1) Endovascular Therapy by vascular surgeons in USA. 2) Therapy for PAD: Strategies by Vascular Surgeons in the USA
  • Invited Lectures, 12th annual meeting of the Encontro Mineiro De Angiologia e Cirurgia Vascular
    Belo Horizonte, Brazil 2012
    1) Behavior of venous grafts and pericardial patches after surgery. 2) Is endovascular treatment the first choice for all patients with PAD? Is there still a role for open surgery? 3) Is it possible to treat TASC D lesions with endovascular techniques? 4) Management of carotid stenosis: What is best, CEA CAS or medical therapy? What do the randomized studies say?
  • Invited lecture, 11th annual Yale-Cambridge Joint Research Program
    Cambridge, United Kingdom 2012
    Understanding vein adaptation to the arterial environment
  • Invited lectures, 11th annual China National Congress of Vascular Surgery
    Changsha, China 2012
    1) How do pericardial patches heal after surgery? 2) Durability considerations for EVAR : selection choices and long term outcomes. 3) Factors for Consideration for Endovascular repair of aortic dissections: a Yale University perspective
  • Modern Alchemy: Turning veins into arteries
    Oxford, United Kingdom 2011
  • Invited Lecture, Controversies & Updates in Vascular Surgery 2011
    Paris, France 2011
    Does a high risk patient for carotid endarterectomy (CEA) exist? / Y-a-t-il des patients à haut risque pour une endartériectomie carotidienne (EAC)
  • Keynote Speaker, 4th China national symposium on vascular disease
    Changsha, China 2011
    New Research on the Etiology of Abdominal Aortic Aneurysms
  • Visiting Professor lecture, Royal Free Hospital
    London, United Kingdom 2011
    Can surgeons turn veins into arteries?
  • Invited lecture - The Litchfield Lecturership
    Oxford, United Kingdom 2011
    Can we turn veins into arteries?
  • Visiting professor lecture, Leeds General Infirmary
    Leeds, United Kingdom 2011
    Healing of vascular grafts and patches: Lessons for tissue engineers
  • Invited lecture, Controversies & Updates in Vascular Surgery 2010
    Paris, France 2010
    La veine peut-elle devenir une artère? Do vein grafts arterialize?
  • Keynote Address, 11th annual congress of the Asian Society for Vascular Surgery
    Kyoto, Japan 2010
    The Future of Bypass Surgery: Lessons from the Embryo
  • Invited Lecture, 9th annual Yale-Cambridge Joint Research Program
    Cambridge, United Kingdom 2010
    Understanding Eph-B4 Control of Vein Graft Adaptation
  • Invited Lectures, CIPRAME (International Conference of Medical Practices) Cardiovascular Disease
    Belo Horizonte, Brazil 2010
    1) Peripheral arterial disease: Diagnosis and Treatment. 2) Cerebrovascular disease: Diagnosis and Treatment
  • Invited lectures, 7th annual Western Vascular Institute Symposium
    Gaillimh, Ireland 2009
    1) Regulation of vessel identity during vein graft adaptation – Are we closer to preventing neointimal hyperplasia?” 2) What’s Happening With Stem Cell Treatments For Lower Limb Ischemia?
  • Invited lecture, 6th annual Western Vascular Institute Symposium
    Gaillimh, Ireland 2008
    Regulation of vessel identity during vein graft adaptation
  • Vascular Biology
    China 2008
    This program is a collaboration between Yale faculty (Dr Alan Dardik) and Central-South University (Dr Chang Shu), encouraging the study of vascular biology. Both basic science (Yale campus) investigations as well as clinical (China campus) investigations are performed.
  • Invited lecture, 35th Annual Meeting of Japanese Society for Vascular Surgery
    Nagoya-shi, Japan 2007
    Peripheral bypass strategy for infrainguinal vascular disease
  • Keynote address, 35th Annual Meeting of Japanese Society for Vascular Surgery
    Nagoya-shi, Japan 2007
    Venous identity is lost but arterial identity is not gained during vein graft adaptation
  • Vascular Biology
    Tokyo, Japan 2007
    This program is a collaboration between Yale faculty (Dr Alan Dardik) and Tokyo Medical University (Dr Toshiya Nishibe), encouraging the study of blood vessels and blood vessel substitutes as used in vascular surgery. Both basic science (Yale campus) investigations as well as clinical (Japan campus) investigations are performed.
  • Invited lecture, Tokyo Medical and Dental University
    Tokyo, Japan 2006
    U.S. update report: Carotid endarterectomy vs. carotid artery stenting
  • Invited lecture, 13th Annual National Conference of the Vascular Society of India
    New Delhi, India 2006
    Carotid endarterectomy: community gold standard for high risk patients
  • Invited lecture, Fujita Health University
    Nagoya-shi, Japan 2005
    Effects of aging on vascular healing
  • Invited lecture, The John Radcliffe Hospital, Oxford University
    Oxford, United Kingdom 1999
    How to build a better blood vessel

Honors & Recognition

AwardAwarding OrganizationDate
The Conrad Jobst LectureshipJobst Vascular Institute2018
SVS Presidential Citation AwardSociety for Vascular Surgery2018
Keynote address, the 39th Annual Scientific Meeting of the Canadian Society for Vascular Surgery, Banff, Canadathe Canadian Society for Vascular Surgery2017
Keynote address, The 2nd China Vascular Congress, Beijing, ChinaThe 2nd China Vascular Congress CVC 20172017
President’s AwardInternational Society for Vascular Surgery2016
The Smithwick Visiting Professorship in Vascular SurgeryBoston University2016
Keynote speaker; 16th Annual Meeting of the Tissue and Cell Engineering Society, London, UKTissue and Cell Engineering Society2016
Keynote speaker; European Society for Vascular Surgery Spring meeting; Frankfurt, GermanyEuropean Society for Vascular Surgery2015
FellowAmerican Surgical Association2015
Master of Arts Degree (honorary)Yale University, New Haven, CT2015
Fellow (FAHA)American Heart Association2014
Keynote Speaker; 11th annual China National Congress of Vascular Surgery, Changsha, ChinaChinese Society for Vascular Surgery2012
Keynote speaker, 12th annual meeting; Belo Horizonte, BrazilEncontro Mineiro De Angiologia e Cirurgia Vascular, Brazil2012
The Litchfield LecturershipOxford University, Oxford, UK2011
Keynote Speaker, 4th annual meeting; Changsha, ChinaChinese National Symposium on Vascular Disease2011
Keynote Speaker, 11th annual congress; Kyoto, JapanAsian Society for Vascular Surgery2010
Distinguished FellowshipSociety for Vascular Surgery2007
Keynote speaker, 35th annual meeting; Nagoya, JapanJapanese Society for Vascular Surgery2007
American College of Surgeons Traveling Fellowship to JapanAmerican College of Surgeons2006
The William J. von Liebig Award (highest ranking vascular surgery basic science research proposal)Lifeline Foundation/American Vascular Association2006
C. Elton Cahow Award for Outstanding Faculty TeachingDepartment of Surgery, Yale University School of Medicine, New Haven, CT2006
Honorable Mention, C. Elton Cahow Award for Outstanding Faculty TeachingDepartment of Surgery, Yale University School of Medicine, New Haven, CT2005
The William J. von Liebig Vascular Academic AwardPeripheral Vascular Surgery Society2004
Faculty Teaching AwardSurgical Residents of St Mary’s Hospital, Waterbury, CT2004
Franklin Martin Faculty Research Fellowship (highest ranking faculty research proposal)American College of Surgeons2002
International Vascular Biology Travel AwardNorth American Vascular Biology Organization2002
E.J.Wylie Traveling FellowshipLifeline Foundation2002
Dennis Jahnigen Career Development Scholar AwardAmerican Geriatrics Society2002
Wylie Scholar in Academic Vascular Surgery AwardVascular Cures2002
Faculty Teaching AwardSurgical Residents of St Mary’s Hospital, Waterbury, CT2002
First Place, Fellow and Resident Paper Competition Chesapeake Vascular Society, Annapolis, MD2000
Surgical Resident and Fellows AwardBaltimore Academy of Surgery, Baltimore, MD1997
Upjohn Award for Clinical ResearchJohns Hopkins University Department of Surgery, Baltimore, MD1997
Upjohn Award for Clinical Research (for outstanding clinical research by a resident member of the Department of Surgery)Johns Hopkins University Department of Surgery, Baltimore, MD1996
Sandoz Surgical Student Research Award (for superior accomplishment in biomedical research)Association for Academic Surgery1993
Balduin Lucke Memorial Prize (for superior research in experimental medicine and biology)University of Pennsylvania School of Medicine, Philadelphia, PA1992
William D Carey Science Award (for an outstanding graduate student in science and engineering)American Association for the Advancement of Science1991
Summa Cum LaudeYale University, New Haven, CT1986
Distinction in the Major, Computer ScienceYale University, New Haven, CT1986
Tau Beta PiYale University, New Haven, CT1985
Phi Beta KappaYale University, New Haven, CT1984
ValedictorianThe Frisch School, Paramus, NJ1982

Professional Service

OrganizationRoleDate
Association of VA Surgeons (AVAS)President2019 - Present
Association of VA SurgeonsPresident-Elect2018 - 2019
Journal of Vascular SurgeryAssociate Editor, Basic Science2018 - Present
Association of VA SurgeonsVice-President2017 - 2018
Agence Nationale de la Recherche (Paris, France)study section2017
Yale University School of MedicineAd Hoc Committee to Review the Criteria for Appointments and Promotions in the Clinician-Educator Track2016 - 2017
NIH NIDDKZRG1 DKUS-J (03) M study section2016
American College of SurgeonsChair, Advisory Council for Vascular Surgery2015 - Present
International Society for Vascular SurgeryMeeting Organizer, ISVS 2015 Annual Congress, Athens, Greece2015
New England Surgical SocietyNew England Surgical Society Scholar Foundation review committee2015 - 2017
Fondazione Cariplo (Milan, Italy)study section2015 - 2017
Society for Vascular SurgeryChair, Research Council2015 - 2018
Society for Vascular SurgeryBoard of Directors2015 - 2018
International Society for Vascular SurgeryPresident2014 - 2016
International Society for Vascular SurgeryMeeting Organizer, ISVS 2014 Annual Congress, Guangzhou China2014
Yale University School of Medicine, Dept of Surgeryreview internal grant applications for the Ohse awards2014 - 2016
Association of VA SurgeonsRecorder2014 - 2017
Yale University School of MedicineSenior Faculty Allotment Committee2013 - 2016
Society for Vascular SurgeryResearch Council2013 - 2018
Journal of Surgical ResearchAssociate Editor2013 - 2017
International Society for Vascular SurgeryVice-President2013 - 2014
Association of VA SurgeonsLocal arrangements committee, Chairman2013 - 2014
AortaEditor for Molecular Biology and Pathophysiology2013 - Present
Society for Vascular SurgeryCourse Director, Emerging Concepts of Vascular Physiology and Therapy, Vascular Research Initiatives Conference (VRIC), Lake Buena Vista, FL2013
Association of VA SurgeonsChairman, Local arrangements committee, AVAS 2014 New Haven meeting2013 - 2014
Rutherford’s Textbook of Vascular Surgery (8th edition)Editor, Basic Science2012 - 2013
Society for Vascular SurgeryCourse Director, Experimental and Applied Vascular Biology, Vascular Research Initiatives Conference (VRIC), Chicago, IL2012
NIH NHLBIBTSS study section2012
NIH NHLBINIH NHLBI Institutional Training Mechanism (NITM) Review Committee2012 - Present
Society for Vascular SurgeryCourse Director, Basic Foundations of Translational Research in Vascular Disease, Vascular Research Initiatives Conference (VRIC), Chicago, IL2011
Association for Academic SurgeryExecutive Committee; Councilor, Class of 20022010 - 2012
Association for Academic SurgeryExecutive Committee; Councilor, Class of 20022010 - 2012
Society for Vascular SurgeryCourse Director, Research Models of Human Vascular Disease, Research Initiatives in Vascular Disease Conference, San Francisco, CA2010
Veterans Affairs (VA)VA Merit Study section; Chair 2011-20122010 - 2012
Society for Vascular SurgeryChair, study section for K08/K23/Wylie traveling/resident/student grants and awards2009 - 2013
International Society for Vascular SurgeryTreasurer2009 - 2013
Society for Vascular SurgeryProgram Committee2009 - 2013
Society for Vascular SurgeryChair of SVS R&E Committee; Faculty Chairman and Course Director of Vascular Research Initiatives Conference (VRIC); Chair, K08/K23/Wylie traveling awards committee2009 - 2013
American Heart AssociationProgram Committee, Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) Spring Conference2009 - 2013
Association of VA SurgeonsResearch Committee2009 - 2012
NIH NHLBIVCMB study section2009
New England Society for Vascular SurgeryExecutive Committee, Councilor-At-Large2008 - 2014
Vascular Cures (Pacific Vascular Research Foundation)Wylie Scholar Award Committee2007 - 2016
American Geriatrics SocietyProgram Committee, Section for Surgical and Related Medical Specialties2007 - 2009
Association for Academic SurgeryProgram Committee2007 - 2009
VascularEditorial Board2007 - Present
Annals of Vascular SurgeryEditorial Board2007 - Present
Society for Vascular SurgeryResearch and Education Committee; Chairman 2009-20132006 - 2013
Peripheral Vascular Surgery SocietySociety Representative to the American College of Surgeons Advisory Council for Vascular Surgery2006 - 2012
VA Connecticut Healthcare Systems, West Haven, CTCompensation and Pay Committee2006 - Present
Journal of Vascular SurgeryEditorial Board2006 - 2012
Eastern Vascular SocietyIssues Committee Chairman 2009-20102006 - 2010
American College of SurgeonsAdvisory Council for Vascular Surgery 2009 - , Liaison to the ACS Program Committee2006 - Present
International Society for Vascular SurgeryRegional Councilor - North America2005 - 2008
VA Connecticut Healthcare Systems, West Haven, CTPreservation-Amputation Care and Treatment (PACT) Committee2005 - Present
Eastern Vascular SocietyYoung Vascular Surgeons Committee2005 - 2009
Association of VA SurgeonsProgram Committee2005 - 2009
New England Society for Vascular SurgeryProgram Committee2004 - 2009
Peripheral Vascular Surgery SocietyMembership Committee2004
Association for Academic SurgeryInformatics and Technology Committee2003 - 2005
Peripheral Vascular Surgery SocietyProgram Committee, Chairman2003 - 2004
Yale University School of Medicine, Department of SurgeryStudent Thesis Committee2002 - Present
VA Connecticut Healthcare Systems, West Haven, CTChair, Surgical Case and Other Invasive Procedure (SOIP) Committee2001 - 2017

Departments & Organizations